Analysis of Quality and Volatile Components in Different Varieties of Pumpkin by Linhong CHEN, Manqin FU, Shengyong LU, Lu LI, Yujuan ZHONG, Junxing LI, Gengsheng XIAO

“…Starch content ranged from 1.06% to 3.65%, showing that 221-09 was the highest and Heixiaobao was the lowest. Fructose and glucose contents were ranged from 21.39 to 57.97 mg/g and 15.74 to 39.51 mg/g, respectively, both of which were the highest value in 221-09 and the lowest value in Xiangyuanzao. …”
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Oxidative stress and impaired insulin secretion in cystic fibrosis pig pancreas by Yunxia O'Malley, Mitchell C. Coleman, Xingshen Sun, Junying Lei, Jianrong Yao, Casey F. Pulliam, Paige Kluz, Michael L. McCormick, Yaling Yi, Yumi Imai, John F. Engelhardt, Andrew W. Norris, Douglas R. Spitz, Aliye Uc

“…Isolated CF pig islets had significantly increased DHE oxidation, peroxide production, reduced insulin secretion in response to high glucose and diminished secretory index compared to non-CF islets. …”
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β-Hydroxybutyrate as an epigenetic modifier: Underlying mechanisms and implications by Yanqiu He, Xi Cheng, Tingting Zhou, Dongze Li, Juan Peng, Yong Xu, Wei Huang

“…Ketogenic diets (KD) have been used as metabolic therapy for over a hundred years, it is well known that ketone bodies and BHB not only serve as ancillary fuel substituting for glucose but also induce anti-oxidative, anti-inflammatory, and cardioprotective features via binding to several target proteins, including histone deacetylase (HDAC), or G protein-coupled receptors (GPCRs). …”
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Effects of Smartphone-Based Remote Interventions on Dietary Intake, Physical Activity, Weight Control, and Related Health Benefits Among the Older Population With Overweight and Ob... by Na Zhang, Mingzhu Zhou, Muxia Li, Guansheng Ma

“…Compared with groups PI and C, group DPI showed a significant decrease in systolic blood pressure (−8.15 vs −3.04 mmHg and −8.15 vs −3.80 mmHg, respectively; P<.05), triglyceride (−0.48 vs 0.11 mmol/L and −0.48 vs 0.18 mmol/L, respectively; P<.05), and fasting blood glucose (−0.77 vs 0.43 mmol/L and −0.77 vs 0.14 mmol/L, respectively; P<.05). …”
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Abstract 109: Endonasal Endoscopic Approach Associated Cerebral Vasospasm and Management: A Case Report by Nefize P. Turan, Matthew Bower, Abdullah Bin Zahid, Ryan P. Lee, Shih‐Chun Lin, Murugappan Ramanathan Jr, Adam Schiavi, Justin M. Caplan

“…Lumbar puncture demonstrated 13 WBC/cu mm with lymphocytic predominance(90%), 23 RBC/cu mm, glucose 89mg/dl, protein 30mg/dl. CSF cultures were negative. …”
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Preoperative Oral Carbohydrate (CHO) Supplementation Is Beneficial for Clinical and Biochemical Outcomes in Patients Undergoing Elective Cesarean Delivery under Spinal Anaesthesia—... by Katarzyna Kotfis, Arleta Wojciechowska, Małgorzata Zimny, Dominika Jamioł-Milc, Aleksandra Szylińska, Sebastian Kwiatkowski, Karolina Kaim, Barbara Dołęgowska, Ewa Stachowska, Maciej Zukowski, Maria Pankowiak, Andrzej Torbé, Paul Wischmeyer

“…Laboratory results in the CHO group showed higher plasma pH (<i>p</i> = 0.001) and glucose (<i>p</i> < 0.001), lower F2-isoprostane in plasma (<i>p</i> = 0.049) and urine (<i>p</i> = 0.018), lower urine F2-isoprostane/creatinine ratio (<i>p</i> = 0.045) than in the SF group. …”
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Alteration of Growth Performance, Antioxidant Capacity, Tissue Fatty Acid Profiles, and Lipid Metabolism of Mud Crab (Scylla paramamosain) Juvenile in Response to Different Dietary... by Fang Fang, Ye Yuan, Min Jin, Yingying Zhang, Tingting Zhu, Jiaxiang Luo, Zheng Yang, Chen Guo, Lefei Jiao, Xiaojun Yan, Qicun Zhou

“…Relative gene expression levels of 6-phosphogluconate dehydrogenase (6pgd) as well as glucose-6-phosphate dehydrogenase (g6pd) have been significantly upregulated in 0.40 and 2.50 g kg-1 ARA groups. …”
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The influence of dapagliflozin on cardiac remodeling, myocardial function and metabolomics in type 1 diabetes mellitus rats by Eder Anderson Rodrigues, Camila Moreno Rosa, Dijon Henrique Salome Campos, Felipe Cesar Damatto, Gilson Masahiro Murata, Lidiane Moreira Souza, Luana Urbano Pagan, Mariana Gatto, Jessica Yumi Brosler, Hebreia Oliveira Almeida Souza, Mario Machado Martins, Luciana Machado Bastos, Suzana Erico Tanni, Katashi Okoshi, Marina Politi Okoshi

“…Abstract Background Sodium-glucose cotransporter (SGLT)2 inhibitors have displayed beneficial effects on the cardiovascular system in diabetes mellitus (DM) patients. …”
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<i>Chiranthodendron pentadactylon</i> Larreat (<i>Sterculiaceae</i>), a Potential Nephroprotector against Oxidative Damage Provoked by STZ-Induced Hyperglycemia in Rats by Eira Santiago-Balmaseda, David Segura-Cobos, María Eugenia Garín-Aguilar, Rubén San Miguel-Chávez, José Melesio Cristóbal-Luna, Eduardo Madrigal-Santillán, Gabriel Alfonso Gutierrez-Rebolledo, Germán Alberto Chamorro-Cevallos, Ricardo Pérez-Pastén-Borja

“…Antioxidant potential in vitro was determined with DPPH and total phenolic tests; antioxidant evaluation in vivo was performed in diabetic rats administered daily via the intragastric route (100 and 200 mg/kg) for 6 weeks; serum glucose/creatinine, food/water consumption, and urinary volume were measured. …”
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Effect of small peptide chelated iron on growth performance, immunity and intestinal health in weaned pigs by Limei M. Sun, Bing Yu, Yuheng H. Luo, Ping Zheng, Zhiqing Huang, Jie Yu, Xiangbing Mao, Hui Yan, Junqiu Luo, Jun He

“…The expression levels of sodium/glucose co-transporter-1 (SGLT1) in ileum (quadratic, P < 0.05) increased quadraticly by different levels of SPCI addition and amino acid transporter-1 (CAT1) in jejunum(P < 0.05) also increased by 100 mg/kg SPCI addition. …”
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Prebiotic Therapy with Inulin Associated with Low Protein Diet in Chronic Kidney Disease Patients: Evaluation of Nutritional, Cardiovascular and Psychocognitive Parameters by Silvia Lai, Sandro Mazzaferro, Maurizio Muscaritoli, Daniela Mastroluca, Massimo Testorio, Adolfo Perrotta, Ylenia Esposito, Maria Carta, Linda Campagna, Marta Di Grado, Cesarina Ramaccini, Sabrina De Leo, Alessandro Galani, Maria Ida Amabile, Alessio Molfino

“…Moreover, at T2 the intervention group showed a reduction in serum insulin (<i>p</i> = 0.008) and fasting glucose levels (<i>p</i> = 0.022), HOMA-IR (<i>p</i> = 0.004), as well as lower total serum cholesterol (<i>p</i> = 0.012), triglycerides (<i>p</i> = 0.016), C-reactive protein (<i>p</i> = 0.044) and homocysteine (<i>p</i> = 0.044) and higher HDL (<i>p</i> < 0.001) with respect to baseline. …”
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Chemical and Bioactive Screening of Green Polyphenol-Rich Extracts from Chestnut By-Products: An Approach to Guide the Sustainable Production of High-Added Value Ingredients by Daniele Bobrowski Rodrigues, Lavínia Veríssimo, Tiane Finimundy, Joana Rodrigues, Izamara Oliveira, João Gonçalves, Isabel P. Fernandes, Lillian Barros, Sandrina A. Heleno, Ricardo C. Calhelha

“…The leaf extracts obtained by MAC-HE and UAE-HE presented the highest concentration of phenolic compounds (70.92 ± 2.72 and 53.97 ± 2.41 mg.g⁻¹ extract dw, respectively), whereas, for burs and shells, the highest recovery of total phenolic compounds was achieved by using UAE-HE and UAE-W (36.87 ± 1.09 and 23.03 ± 0.26 mg.g⁻¹ extract dw, respectively). Bis-HHDP-glucose isomers, chestanin and gallic acid were among the most abundant compounds. …”
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CIRP attenuates acute kidney injury after hypothermic cardiovascular surgery by inhibiting PHD3/HIF-1α-mediated ROS-TGF-β1/p38 MAPK activation and mitochondrial apoptotic pathways... by Peiyao Zhang, Liting Bai, Yuanyuan Tong, Shengwen Guo, Wenlong Lu, Yue Yuan, Wenting Wang, Yu Jin, Peng Gao, Jinping Liu

“…Then, we established the hypothermic oxygen–glucose deprivation (OGD) model using HK-2 cells transfected with siRNA to verify the downstream pathways and explore potential pharmacological approach. …”
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Effects of light therapy on sleep and circadian rhythm in older type 2 diabetics living in long-term care facilities: a randomized controlled trial by Qin Wang, Qin Wang, Shuang Wu, Zhenhua Luo, Lihui Pu, Xiaoxia Wang, Maoting Guo, Mingjiao Zhang, Hongxia Tang, Mengjie Chen, Laixi Kong, Ping Huang, Liyuan Chen, Zhe Li, Zhe Li, Dan Zhao, Zhenzhen Xiong, Zhenzhen Xiong

“…However, no discernible alterations in blood glucose levels were detected in this study.…”
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From Diabetes Care to Heart Failure Management: A Potential Therapeutic Approach Combining SGLT2 Inhibitors and Plant Extracts by Micaela Gliozzi, Roberta Macrì, Anna Rita Coppoletta, Vincenzo Musolino, Cristina Carresi, Miriam Scicchitano, Francesca Bosco, Lorenza Guarnieri, Antonio Cardamone, Stefano Ruga, Federica Scarano, Saverio Nucera, Rocco Mollace, Irene Bava, Rosamaria Caminiti, Maria Serra, Jessica Maiuolo, Ernesto Palma, Vincenzo Mollace

“…Over the years, multiple pharmacological approaches aimed at controlling blood glucose levels were unable to significantly reduce diabetes-related cardiovascular events. …”
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Biocompatible MXene (Ti₃C₂T_x) Immobilized with Flavin Adenine Dinucleotide as an Electrochemical Transducer for Hydrogen Peroxide Detection in Ovar... by Ramila D. Nagarajan, Preethika Murugan, Kanagaraj Palaniyandi, Raji Atchudan, Ashok K. Sundramoorthy

“…The optimization of FAD deposition, amount of Ti₃C₂T_x loading, effect of pH and the interference study with common biochemicals such as glucose, lactose, dopamine (DA), potassium chloride (KCl), ascorbic acid (AA), amino acids, uric acid (UA), oxalic acid (OA), sodium chloride (NaCl) and acetaminophen (PA) have been carried out. …”
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Partial Characterization and Immunomodulatory Effects of Exopolysaccharides from <i>Streptococcus thermophilus</i> SBC8781 during Soy Milk and Cow Milk Fermentation by Hajime Nakata, Yoshiya Imamura, Sudeb Saha, René Emanuel Lobo, Shugo Kitahara, Shota Araki, Mikado Tomokiyo, Fu Namai, Masanori Hiramitsu, Takashi Inoue, Keita Nishiyama, Julio Villena, Haruki Kitazawa

“…EPS-s and EPS-m had heteropolysaccharide structures formed by galactose, glucose, rhamnose, ribose, and mannose, although with different monomer proportions. …”
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Comparative analysis of different response criteria at early phase after PD-1 blockade in non-small lung cancer by Kyoichi Kaira, Ou Yamaguchi, Ichiro Naruse, Yukihiro Umeda, Takeshi Honda, Satoshi Watanabe, Kosuke Ichikawa, Shin Yanagisawa, Norimitsu Kasahara, Tetsuya Higuchi, Kosuke Hashimoto, Yu Miura, Ayako Shiono, Atsuto Mouri, Hisao Imai, Kunihiko Iizuka, Tamotsu Ishizuka, Koichi Minato, Satoshi Suda, Hiroshi Kagamu, Keita Mori, Nobuhiko Seki, Ichiei Kuji

“…Methods A total of 54 patients with advanced NSCLC who had 2-deoxy-2-[fluorine-18]-fluoro-D-glucose PET or CT at baseline, and 4 and 9 weeks after PD-1 blockade, were registered. …”
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Metabolomic analysis in spondyloarthritis: A systematic review by Tianwen Huang, Tianwen Huang, Tianwen Huang, Yaoyu Pu, Yaoyu Pu, Yaoyu Pu, Xiangpeng Wang, Xiangpeng Wang, Xiangpeng Wang, Yanhong Li, Yanhong Li, Yanhong Li, Hang Yang, Hang Yang, Hang Yang, Yubin Luo, Yubin Luo, Yubin Luo, Yi Liu, Yi Liu, Yi Liu

“…SpA patients showed higher levels of glucose, succinic acid, malic acid and lactate in carbohydrate metabolism, higher glycerol levels and lower fatty acid (especially unsaturated fatty acid) levels in lipid metabolism, and lower levels of tryptophan and glutamine in amino acid metabolism than healthy controls. …”
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Treatment-Induced Neuropathy in Diabetes (TIND)—Developing a Disease Model in Type 1 Diabetic Rats by Petra Baum, Severin Koj, Nora Klöting, Matthias Blüher, Joseph Classen, Sabine Paeschke, Martin Gericke, Klaus V. Toyka, Marcin Nowicki, Joanna Kosacka

“…We serially examined blood glucose and HbA1c levels, motor- and sensory/mixed afferent conduction velocities (mNCV and csNCV) and peripheral nerve morphology, including intraepidermal nerve fiber density and numbers of Iba-1 (ionized calcium binding adaptor molecule 1) positive macrophages in the sciatic nerve. …”
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