CircDOCK7 facilitates the proliferation and adipogenic differentiation of chicken abdominal preadipocytes through the gga-miR-301b-3p/ACSL1 axis by Weihua Tian, Ye Liu, Wenhui Zhang, Ruixue Nie, Yao Ling, Bo Zhang, Hao Zhang, Changxin Wu

“…Functionally, the gain- and loss-of-function experiments showed that circDOCK7 promoted proliferation, G0/G1- to S-phase progression, and glucose uptake capacity of chicken abdominal preadipocytes, in parallel with adipogenic differentiation characterized by remarkably increased intracellular lipid droplet accumulation and triglyceride and acetyl coenzyme A content in differentiated chicken abdominal preadipocytes. …”
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Study protocol for family model diabetes self-management education with Marshallese participants in faith-based organizations by Pearl A. McElfish, Sheldon Riklon, Rachel S. Purvis, Christopher R. Long, Holly C. Felix, Jonell S. Hudson, Derek Alik, Joseph Henske, Dinesh Edem, Gail O'Connor, Janine Boyers, Brett Rowland, James P. Selig

“…Secondary measures include glucose, weight, body mass index, blood pressure, diabetes self-management behaviors, and diabetes management self-efficacy. …”
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Platelet-derived thrombospondin 1 promotes immune cell liver infiltration and exacerbates diet-induced steatohepatitis by Taesik Gwag, Sangderk Lee, Zhenyu Li, Alana Newcomb, Josephine Otuagomah, Steven A. Weinman, Ying Liang, Changcheng Zhou, Shuxia Wang

“…Results: Although TSP1 deletion in platelets did not affect diet-induced steatosis, TSP1Δpf4 mice exhibited attenuated NASH and liver fibrosis, accompanied by improvements in plasma glucose and lipid homeostasis. Furthermore, TSP1Δpf4 mice showed reduced intrahepatic platelet accumulation, activation, and chemokine production, correlating with decreased immune cell infiltration into the liver. …”
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Prevalence and Associated Risk Factors of Urinary Tract Infection among Diabetic Patients: A Cross-Sectional Study by Anas Elyas Ahmed, Suhaila Abdelkarim, Maria Zenida, Maisa Ali Hussein Baiti, Atyaf Abbas Yahya Alhazmi, Bushra Ahmed Hussain Alfaifi, Rania Qarmoush Mohammed Majrabi, Nidaa Qasem M. Khormi, Alyaj Alla Ali Hakami, Rafa Abdu Mohammed Alqaari, Raffan Ahmed Alhasani, Ramzi Abdu Alajam, Mohammed M. Alshehri, Aqeel M. Alenazi, Bader Alqahtani, Meshal Alshamrani, Ahmed Alhowimel, Siddig Ibrahim Abdelwahab

“…Additionally, various factors, such as socio-demographics, type of DM, fasting blood glucose, regular diabetes monitoring, comorbid chronic diseases, HbA1c, body mass index (BMI), and duration of DM, are also thought to predispose individuals to developing UTIs more frequently when they have DM. …”
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1-year weight change after diabetes diagnosis and long-term incidence and sustainability of remission of type 2 diabetes in real-world settings in Hong Kong: An observational cohor... by Hongjiang Wu, Aimin Yang, Eric S H Lau, Xinge Zhang, Baoqi Fan, Ronald C W Ma, Alice P S Kong, Elaine Chow, Wing-Yee So, Juliana C N Chan, Andrea O Y Luk

“…Diabetes remission was defined as 2 consecutive HbA1c <6.5% measurements at least 6 months apart in the absence of glucose-lowering drugs (GLDs) and with no record of GLDs at least 3 months before these measurements. …”
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Genome-wide association study identifies novel candidate loci or genes affecting stalk strength in maize by Shuhui Xu, Xiao Tang, Xiaomin Zhang, Houmiao Wang, Weidong Ji, Chenwu Xu, Zefeng Yang, Pengcheng Li

“…By combining the GWAS data with public gene expression data, 56 candidate genes within 50 kb of the significant SNPs were identified, including genes encoding flavonol synthase (GRMZM2G069298, ZmFLS2), nitrate reductase (GRMZM5G878558, ZmNR2), glucose-1-phosphate adenylyltransferase (GRMZM2G027955), and laccase (GRMZM2G447271). …”
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circDNMT1 Promotes Malignant Progression of Gastric Cancer Through Targeting miR-576-3p/Hypoxia Inducible Factor-1 Alpha Axis by Hanghang Li, Hanghang Li, Bo Cao, Bo Cao, Ruiyang Zhao, Ruiyang Zhao, Tian Li, Xingming Xu, Hao Cui, Huan Deng, Huan Deng, Jingwang Gao, Jingwang Gao, Bo Wei

“…Glycolysis of GC cells was detected based on the levels of glucose uptake, the lactate acid, ATP and pyruvic acid production and the extracellular acidification and oxygen consumption rates. …”
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Combined Therapy with a CCR2/CCR5 Antagonist and FGF21 Analogue Synergizes in Ameliorating Steatohepatitis and Fibrosis by Tobias Puengel, Sander Lefere, Jana Hundertmark, Marlene Kohlhepp, Christian Penners, Frederique Van de Velde, Bruno Lapauw, Anne Hoorens, Lindsey Devisscher, Anja Geerts, Stephanie Boehm, Qihong Zhao, John Krupinski, Edgar D. Charles, Bradley Zinker, Frank Tacke

“…Fibroblast growth factor 21 (FGF21) may improve NASH by modulating lipid and glucose metabolism. We compared effects of single drug to combination treatment as therapeutic strategies against NASH. (2) Methods: We analyzed serum samples and liver biopsies from 85 nonalcoholic fatty liver disease (NAFLD) patients. …”
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<i>C9ORF72</i> Repeat Expansion Affects the Proteome of Primary Skin Fibroblasts in ALS by Marta Lualdi, Adeena Shafique, Edoardo Pedrini, Luisa Pieroni, Viviana Greco, Massimo Castagnola, Giorgia Cucina, Lucia Corrado, Alice Di Pierro, Fabiola De Marchi, Lara Camillo, Claudia Colombrita, Marianna D’Anca, Tiziana Alberio, Sandra D’Alfonso, Mauro Fasano

“…Moreover, we highlighted novel molecular pathways (nuclear and mitochondrial transports, vesicle trafficking, mitochondrial bioenergetics, glucose metabolism, ER-phagosome crosstalk and Slit/Robo signaling pathway) which might be further investigated as <i>C9ORF72</i>-specific pathogenetic mechanisms. …”
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Preliminary investigation of the effect of non-cardiac surgery on intraoperative islet and renal function: a single-center prospective cohort study by Yongtao Sun, Xiaoning Zhang, Min Zhang, Yongle Guo, Yongle Guo, Tao Sun, Mengjie Liu, Xiaojun Gao, Yang Liu, Zhongquan Gao, Zhongquan Gao, Lina Chen, Xiaoyan Du, Yuelan Wang, Yuelan Wang

“…The correlation analysis showed that hematocrit (HCT) and hemoglobin (HB) were negatively correlated with fasting plasma glucose (FPG) (p &lt; 0.05), MAP was positively correlated with C-peptide (p &lt; 0.05), and HCT and Hb were positively correlated with serum creatinine (SCr) (p &lt; 0.05). …”
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Clinical [¹⁸F]FSPG Positron Emission Tomography Imaging Reveals Heterogeneity in Tumor-Associated System x_c⁻ Activity by Amy R. Sharkey, Norman Koglin, Erik S. Mittra, Sangwon Han, Gary J. R. Cook, Timothy H. Witney

“…[¹⁸F]FSPG time–activity curves (TACs) for normal organs, primary tumors and metastases were subsequently compared to ¹⁸F-2-fluoro-2-deoxy-D-glucose ([¹⁸F]FDG) PET/CT at 60 min post injection (p.i.). …”
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Causality of particulate matter on cardiovascular diseases and cardiovascular biomarkers by Qiubo Wang, Qiubo Wang, Zhimiao Wang, Mingyou Chen, Wei Mu, Zhenxing Xu, Mei Xue

“…To explore the causality of PM on CVDs and cardiovascular biomarkers, we conducted a Mendelian randomization (MR) analysis.MethodIn this study, we obtained summary-level data for CVDs and cardiovascular biomarkers including atrial fibrillation (AF), heart failure (HF), myocardial infarction (MI), ischemic stroke (IS), stroke subtypes, body mass index (BMI), lipid traits, fasting glucose, fasting insulin, and blood pressure from several large genome-wide association studies (GWASs). …”
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Disrupting arrhythmia in a professional male wrestler athlete after rapid weight loss and high-intensity training—Case report by Aleksandra Milovančev, Aleksandra Milovančev, Tatjana Miljković, Tatjana Miljković, Aleksandra Ilić, Aleksandra Ilić, Anastazija Stojšić Milosavljević, Anastazija Stojšić Milosavljević, Milovan Petrović, Milovan Petrović, Roberto Roklicer, Nemanja Lakičević, Tatjana Trivić, Patrik Drid

“…After P1 RWL simulation, he lost 5.15% of body weight in 3 days, which resulted in lower blood glucose levels, higher urea, creatinine, creatine kinase (CK), CK-MB levels, and slightly increased levels of NT pro-BNP, ECG revealed sinus rhythm with one ventricular premature beat (VPB), 24-h continuous electrocardiogram (ECG) revealed frequent ventricular premature beats (PVB) 2,150/ 24 h, with two couplets, and 8 PAC. …”
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A prospective study of risk factors for neurological complications in childhood bacterial meningitis by Sadie Namani, Zvonko Milenković, Bulëza Koci

“…Initial pleocytosis > 5,000 cells/mm3, pleocytosis > 5,000 cells/mm3 after 48 hours, CSF/blood glucose ratio < 0.20, female gender, previous treatment with antibiotics, community-acquired infection, duration of illness > 48 hours, presence of comorbidity, and primary focus of infection were not associated with increased risk for the development of neurological complications. …”
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An increase in myocardial 18-fluorodeoxyglucose uptake is associated with left ventricular ejection fraction decline in Hodgkin lymphoma patients treated with anthracycline by Matteo Sarocchi, Matteo Bauckneht, Eleonora Arboscello, Selene Capitanio, Cecilia Marini, Silvia Morbelli, Maurizio Miglino, Angela Giovanna Congiu, Giorgio Ghigliotti, Manrico Balbi, Claudio Brunelli, Gianmario Sambuceti, Pietro Ameri, Paolo Spallarossa

“…At the cellular level, this cardiotoxicity includes deranged cardiac glucose metabolism. Methods By reviewing the hospital records from January 2008 through December 2016, we selected HL patients meeting the following criteria: ≥ 18 year-old; first-line DOX-containing chemotherapy; no diabetes and apparent cardiovascular disease; 18-fluoro-deoxyglucose positron emission tomography (18FDG-PET) scans before treatment (PETSTAGING), after 2 cycles (PETINTERIM) and at the end of treatment (PETEOT); at least one echocardiography ≥ 6 months after chemotherapy completion (ECHOPOST). …”
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Daily running enhances molecular and physiological circadian rhythms in skeletal muscle by Nuria Casanova-Vallve, Drew Duglan, Megan E. Vaughan, Marie Pariollaud, Michal K. Handzlik, Weiwei Fan, Ruth T. Yu, Christopher Liddle, Michael Downes, Julien Delezie, Rebecca Mello, Alanna B. Chan, Pål O. Westermark, Christian M. Metallo, Ronald M. Evans, Katja A. Lamia

“…Patterns of gene expression were analyzed using Gene Set Enrichment Analysis (GSEA) and Detection of Differential Rhythmicity (DODR). Blood glucose, lactate, and ketones, and muscle and liver glycogen were measured before and after exercise. …”
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Entrevista motivacional no autogerenciamento de cuidados a adolescentes com diabetes tipo 1: revisão integrativa [Motivational interviewing and self-management among adolescents wi... by Laura Martins Mendes Cavaleiro Brito, Maria da Conceição dos Santos Oliveira Cunha, Amanda Newle Sousa Silva, Maria Veraci Oliveira Queiroz

“…The studies used different methods for applying motivational interviewing in differing circumstances, and their findings revealed positive impacts on self-management among adolescents with type-1 diabetes, especially on blood glucose monitoring and/or on glycated hemoglobin levels. …”
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Microenvironment responsive nanocomposite hydrogel with NIR photothermal therapy, vascularization and anti-inflammation for diabetic infected wound healing by Shuangli Zhu, Bangjiao Zhao, Maocai Li, Hao Wang, Jiayi Zhu, Qingtao Li, Huichang Gao, Qi Feng, Xiaodong Cao

“…Metformin had a pH and glucose responsive release behavior to treat different wound microenvironment intelligently. …”
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Text message-based intervention, Keeping in Touch (KiT), to support youth as they transition to adult type 1 diabetes care: a protocol for a multisite randomised controlled superio... by Gillian L Booth, Peter Austin, Laura Desveaux, Elise Mok, Melanie Henderson, Meranda Nakhla, Joseph A Cafazzo, Valeria E Rac, Rayzel Shulman, Geetha Sanmugalingham, Anne-Sophie Brazeau, Marley Greenberg, Jessica Kichler, Ellen Goldbloom, Alanna Landry, Ian Zenlea, Madison Taylor

“…Secondary outcomes, measured at 6 and 12 months, include transition readiness, perceived T1D-related stigma, time between final paediatric and first adult diabetes visits, haemoglobin A1c, and other glycaemia measures (for continuous glucose monitor users), diabetes-related hospitalisations and emergency department visits and the cost of implementing the intervention. …”
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Quality and Quantity of Protein Intake Influence Incidence of Type 2 Diabetes Mellitus in Coronary Heart Disease Patients: From the CORDIOPREV Study by Silvia de la Cruz-Ares, Francisco M. Gutiérrez-Mariscal, Juan F. Alcalá-Díaz, Gracia M. Quintana-Navarro, Alicia Podadera-Herreros, Magdalena P. Cardelo, José D. Torres-Peña, Antonio P. Arenas-de Larriva, Pablo Pérez-Martínez, Javier Delgado-Lista, Elena M. Yubero-Serrano, José López-Miranda

“…At baseline and during the follow-up, patients underwent medical examination and blood and oral glucose tolerance tests. Information on patient’s dietary intake was gathered by registered dietitians using a validated food frequency questionnaire. …”
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