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50741
Features of cerebral stroke course in patients with diabetes mellitus according to the REGION-M register
Published 2019-11-01“…Patients with diabetes were older than patients without diabetes and impaired glucose tolerance (73,7+11,1 years vs 69,6±14,7 years (p<0,05)), more often had a history of coronary artery disease (74,2% vs 52,3%, respectively (p<0,05)) myocardial infarction (29,6% and 16,6%, respectively (p<0,05)). …”
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50742
The Level of Adipokine Metrnl and Its Relationship with Inflammation and Insulin Resistance in Patients with Obstructive Sleep Apnea Syndrome
Published 2023-10-01“…General data of the 3 groups was collected, including fasting blood glucose (FBG), fasting insulin (FINS), total cholesterol (TC), triglycerides (TG), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), glycosylated hemoglobin A1c (HbA1c), uric acid (UA), Metrnl, nuclear factor-κB (NF-κB), IL-6, TNF-α, IL-10 and IL-4 levels. …”
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50743
The opportunities and challenges of the disease-modifying immunotherapy for type 1 diabetes: A systematic review and meta-analysis
Published 2024-05-01“…We included clinical trials of immunotherapy conducted in patients with T1D that reported the incidence of hypoglycemia or changes from baseline in at least one of following outcomes: 2 h and 4 h mixed-meal-stimulated C-peptide area under the curve (AUC), fasting C-peptide, daily insulin dosage, glycated hemoglobin (HbA1c) and fasting plasma glucose (FPG). The results were computed as the weighted mean differences (WMDs) or odds ratios (ORs) and 95% confidence intervals (CIs) in random-effect model. …”
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50744
2型糖尿病患者的随访频率和临床结局:一项基于多中心真实数据的前瞻性分析
Published 2022-05-01“…Patients with HFF showed significantly greater decrease in percentage changes of fasting blood glucose (−4.95% ± 37.96% vs −2.21% ± 43.08%, P < .0001) and glycosylated hemoglobin (HbA1c) (−12.14% ± 19.78% vs −9.67% ± 20.29%, P < .0001) after adjustments compared to those with LFF. …”
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50745
Effects of Daily Raspberry Consumption on Immune-Metabolic Health in Subjects at Risk of Metabolic Syndrome: A Randomized Controlled Trial
Published 2020-12-01“…The intervention did not significantly affect plasma insulin, glucose, inflammatory marker concentrations, nor blood pressure. …”
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50746
Risk factors of hemorrhagic transformation in acute ischaemic stroke: A systematic review and meta-analysis
Published 2023-02-01“…Common predictors for symptomatic ICH (sICH) after reperfusion therapies were age and serum glucose level. Atrial fibrillation (OR = 3.867, 95% CI 1.970–7.591, I2 = 29.1%), NIHSS score (OR = 1.082, 95% CI 1.060–1.105, I2 = 54.5%) and onset-to-treatment time (OR = 1.003, 95% CI 1.001–1.005, I2 = 0.0%) were predictors of sICH after IVT. …”
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50747
Comparative evaluation of ethyl acetate and n‐Hexane extracts of Cannabis sativa L. leaves for muscle function restoration after peripheral nerve lesion
Published 2023-06-01“…A prominent increase in total antioxidant capacity (TAC) (M = 3.76, SD = 0.38, p < .001) and momentous decrease in total oxidant status (TOS) (M = 11.28, SD = 5.71, p < .001) along with blood glucose level indicated significant difference (M = 105.5, SD = 9.12, p < 0.001) in treatment 1 group. …”
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50748
Dysregulated glucuronic acid metabolism exacerbates hepatocellular carcinoma progression and metastasis through the TGFβ signalling pathway
Published 2022-08-01“…Results GSTZ1 was universally silenced in both human and murine HCC cells, and its deficiency contributed to HCC metastasis in vitro and in vivo. UDP‐glucose 6‐dehydrogenase (UGDH)‐mediated UDP‐glucuronic acid (UDP‐GlcUA) accumulation promoted hepatoma cell migration upon GSTZ1 loss. …”
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50749
Lipidome characterisation and sex-specific differences in type 1 and type 2 diabetes mellitus
Published 2024-03-01“…The models were adjusted by sex, age, hypertension, dyslipidaemia, body mass index, glucose, smoking, systolic blood pressure, triglycerides, HDL cholesterol, LDL cholesterol, alternate Mediterranean diet score (aMED) and estimated glomerular filtration rate (eGFR); diabetes duration and glycated haemoglobin (HbA1c) were also included in the comparison between T1D and T2D. …”
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50750
Cost-effectiveness of two screening strategies based on Chinese diabetes risk score for pre-diabetes in China
Published 2022-11-01“…The screening strategy of the control group was screening for pre-DM by fasting plasma glucose (FPG) test in adults undergoing annual health examination and no screening in adults without an annual health examination (status quo). …”
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50751
Positive association between insulin resistance and fatty liver disease in psoriasis: evidence from a cross-sectional study
Published 2024-04-01“…IR was assessed using the triglyceride glucose (TyG) and TyG-body mass index (TyG-BMI) indicators. …”
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50752
Sphenoid sinus is a rare site for tumor-induced osteomalacia: A case report and literature review
Published 2023-03-01“…Interestingly, 2-deoxy-2-[fluorine-18]fluoro-d-glucose positron emission tomography/computed tomography (18F-FDG PET/CT) detected a tumor in the axilla and another in the sphenoid sinus, but only the tumor in the sphenoid sinus had somatostatin receptor (SSTR) expression in 68-gallium 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid octreotate (Ga-68 DOTATATE) PET/CT. …”
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50753
Is it possible to achieve an acceptable disease control by dietary therapy alone in Berardinelli Seip type 1? Experience from a case report
Published 2023-06-01“…Biochemistry, hormonal evaluation, 75 mg oral glucose tolerance test, cardiac evaluation and abdominal ultrasound were performed, revealing no abnormalities. …”
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50754
High-frequency repetitive transcranial magnetic stimulation (rTMS) protects against ischemic stroke by inhibiting M1 microglia polarization through let-7b-5p/HMGA2/NF-κB signaling...
Published 2022-08-01“…Methods Previously reported 10 Hz rTMS protocol that regulated astrocytic polarization was used to stimulate transient middle cerebral artery occlusion (MCAO) rats and oxygen and glucose deprivation/reoxygenation (OGD/R) injured BV2 cells. …”
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50755
Antioxidant Effect of the Ethyl Acetate Extract of <i>Potentilla indica</i> on Kidney Mitochondria of Streptozotocin-Induced Diabetic Rats
Published 2023-09-01“…At the end of the treatment, fasting blood glucose (FBG) levels, creatinine, blood urea nitrogen (BUN), and uric acid were estimated. …”
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50756
Fenbendazole Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice via Suppression of Fibroblast-to-Myofibroblast Differentiation
Published 2022-11-01“…Further studies showed that FBZ significantly inhibited glucose consumption, moderated glycolytic metabolism in fibroblasts, thus activated adenosine monophosphate-activated protein kinase (AMPK), and reduced the activation of the mammalian target of rapamycin (mTOR) pathway, thereby inhibiting transforming growth factor-β (TGF-β1)-induced fibroblast-to-myofibroblast differentiation and collagen synthesis. …”
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50757
Study on the construction technology of β-alanine synthesizing Escherichia coli based on cellulosome assembly
Published 2023-06-01“…To avoid pollution caused by traditional production methods, the synthesis of β-alanine has been gradually replaced by microbial fermentation and enzyme catalysis, which is a green, mild, and high-yield biosynthesis method.Methods: In this study, we constructed an Escherichia coli recombinant strain for efficient β-alanine production using glucose as the raw material. The microbial synthesis pathway of L-lysine-producing strain, Escherichia coli CGMCC 1.366, was modified using gene editing by knocking out the aspartate kinase gene, lysC. …”
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50758
Diabetic ketoacidosis in a pediatric intensive care unit
Published 2017-03-01“…The following data regarding 52 admissions were analyzed: age, sex, weight, body surface area, signs, symptoms and severity on admission, blood gas, blood glucose, glycated hemoglobin, serum osmolarity, and index of mortality. …”
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50759
L’hormone de croissance recombinante : intérêt et risques potentiels de son utilisation pour la production laitière bovine
Published 1998-02-01“…Simultanément, la GH oriente le métabolisme du tissu adipeux et du muscle vers une mobilisation et une oxydation accrues des acides gras, et une épargne du glucose. L’administration de rbGH a peu d’effets directs sur la fonction de reproduction, mais tend indirectement à la retarder, lorsqu’elle est initiée avant la fécondation, en raison de la diminution transitoire du bilan énergétique des vaches. …”
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50760
3384 Serum Metabolites from the Trimethylamine Pathway Associate with Left Ventricular Diastolic Function: The Bogalusa Heart Study
Published 2019-03-01“…Covariates adjusted for included sex, age, race, education, alcohol drinking, cigarette smoking, heart rate, systolic blood pressure, glomerular filtrate rate, body mass index, low density lipoprotein cholesterol, high density lipoprotein cholesterol, hemoglobin A1c, serum triglycerides, as well as blood pressure-, lipid-, and glucose-lowering medications. RESULTS/ANTICIPATED RESULTS: After stringent Bonferroni correction for multiple testing, four TMA-associated metabolites as well the TMA score were significantly associated with diastolic function. …”
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