Silencing the Adipocytokine NOV: A Novel Approach to Reversing Oxidative Stress-Induced Cardiometabolic Dysfunction by Maayan Waldman, Shailendra P. Singh, Hsin-Hsueh Shen, Ragin Alex, Rita Rezzani, Gaia Favero, Edith Hochhauser, Ran Kornowski, Michael Arad, Stephen J. Peterson

“…Inhibiting NOV expression increases PGC-1, a key component of cardiac bioenergetics, as well as key signaling components of metabolic change, resulting in improved glucose tolerance, improved mitochondrial function, and decreased inflammation. …”
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Comparative genomics reveals insight into the phylogeny and habitat adaptation of novel Amycolatopsis species, an endophytic actinomycete associated with scab lesions on potato tub... by Thippawan Wannawong, Wuttichai Mhuantong, Wuttichai Mhuantong, Pipat Macharoen, Nantawan Niemhom, Jaruwan Sitdhipol, Neungnut Chaiyawan, Sarinna Umrung, Somboon Tanasupawat, Nakarin Suwannarach, Nakarin Suwannarach, Yukihiro Asami, Yukihiro Asami, Nattakorn Kuncharoen

“…Strain MEP2-6T is a gram-positive filamentous bacteria characterized by meso-diaminopimelic acid in cell wall peptidoglycan and arabinose, galactose, glucose, and ribose in whole-cell hydrolysates. Diphosphatidylglycerol, phosphatidylglycerol, phosphatidylethanolamine, and hydroxy-phosphatidylethanolamine were the major phospholipids, of which MK-9(H6) was the predominant menaquinone, whereas iso-C16:0 and iso-C15:0 were the major cellular fatty acids. …”
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ROS Induced by <i>Streptococcus agalactiae</i> Activate Inflammatory Responses via the TNF-α/NF-κB Signaling Pathway in Golden Pompano <i>Trachinotus ovatus</i> (Linnaeus, 1758) by Jie Gao, Mingjian Liu, Huayang Guo, Kecheng Zhu, Bo Liu, Baosuo Liu, Nan Zhang, Dianchang Zhang

“…After infection with <i>S. agalactiae</i>, the content of reactive oxygen species (ROS) in serum was significantly increased (<i>p</i> < 0.05). Serum levels of glucose (GLU), alanine aminotransferase (ALT), aspartate aminotransferase (AST), and malondialdehyde (MDA) increased and then decreased (<i>p</i> < 0.05), reaching a maximum at 6 h. …”
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Determination of Soluble Sugar and Organic Acid Components and Evaluation of Taste Quality of 11 Main Cultivars of Lentinula edodes by Wanchao CHEN, Wen LI, Di WU, Zhong ZHANG, Shuai ZHOU, Yan YANG, Jinsong ZHANG, Hailong YU

“…The results showed that four kinds of soluble sugar, mannitol, trehalose, arabinose and glucose, in which mannitol and trehalose were main. …”
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Omega-6 fatty acids and the risk of cardiovascular disease: insights from a systematic review and meta-analysis of randomized controlled trials and a Mendelian randomization study by Mohsen Mazidi, Niloofar Shekoohi, Niki Katsiki, Maciej Banach, the Lipid and Blood Pressure Meta-analysis Collaboration (LBPMC) Group

“…In contrast, MR showed that individuals with higher serum omega-6 acid – adrenic acid (AA) levels had a greater risk for CHD events (IVW β = 0.526), MI (IVW β = 0.606) and large artery stroke (IVW β = 1.694), as well as increased levels of fasting blood glucose (FBG) (IVW β = 0.417), low-density lipoprotein cholesterol (LDL-C) (IVW β = 0.806), high-density lipoprotein cholesterol (HDL-C) (IVW β = 0.820), and lower levels of triglycerides (TG) (IVW β = –1.064) and total cholesterol (TC) (IVW β = –1.064). …”
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Development of UPLC-MS/MS Method to Study the Pharmacokinetic Interaction between Sorafenib and Dapagliflozin in Rats by Xueru He, Ying Li, Yinling Ma, Yuhao Fu, Xuejiao Xun, Yanjun Cui, Zhanjun Dong

“…Dapagliflozin (DAPA), a sodium–glucose cotransporter-2 inhibitor (SGLT2i), is widely used in patients with T2DM. …”
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Neurofibromatosis Type 1 Has a Wide Spectrum of Growth Hormone Excess by Fady Hannah-Shmouni, Giampaolo Trivellin, Pablo Beckers, Lefkothea P. Karaviti, Maya Lodish, Christina Tatsi, Adekunle M. Adesina, Fotini Adamidou, Gesthimani Mintziori, Jami L. Josefson, Martha Quezado, Constantine A. Stratakis

“…GH excess was confirmed by the failure to suppress GH (<1 ng/mL) on oral glucose tolerance test (OGTT, <i>n</i> = 9) and frequent overnight sampling of GH levels (<i>n</i> = 6). …”
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Risk factors associated with attendance at postpartum blood pressure follow-up visit in discharged patients with hypertensive disorders of pregnancy by Jingjing Li, Qin Zhou, Yixuan Wang, Lufen Duan, Guangjuan Xu, Liping. Zhu, Liping Zhou, Lan Peng, Lian. Tang, Yanxia. Yu

“…Likewise, females with HDP in China should have a BP evaluation continuously for at least 42 days postpartum and have BP, urine routine, and lipid and glucose screening for 3 months postpartum. Methods This study is a prospective cohort study of postpartum discharged HDP patients. …”
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Acid pH Strategy Adaptation through <i>NRG1</i> in <i>Ustilago maydis</i> by José Alejandro Sánchez-Arreguin, José Ruiz-Herrera, F. de Jesus Mares-Rodriguez, Claudia Geraldine León-Ramírez, Lino Sánchez-Segura, Patricio Adrián Zapata-Morín, Jordan Coronado-Gallegos, Elva Teresa Aréchiga-Carvajal

“…Among previously described specific functions of this transcriptional regulator, it was found to be involved in glucose repression, metabolic adaptation to adverse conditions, cellular transport, cell rescue, defense and interaction with an acidic pH environment.…”
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Time-of-Day-Dependent Effects of Bromocriptine to Ameliorate Vascular Pathology and Metabolic Syndrome in SHR Rats Held on High Fat Diet by Michael Ezrokhi, Yahong Zhang, Shuqin Luo, Anthony H. Cincotta

“…While the improvement of glycemic control is largely the result of improved postprandial hepatic glucose metabolism and insulin action, the mechanisms underlying the drug’s cardioprotective effects are less well defined. …”
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Pattern of Adiponectin, Osteocalcin, Irisin, FGF-21, and MCP-1 According to the Body Size Phenotype: Could They Be Markers of Metabolic Health in Mexican-Mestizo Middle-Aged Women? by Lourdes Balcázar-Hernandez, Lourdes Basurto, Leticia Manuel-Apolinar, Sara Vega-García, Norma Basurto-Acevedo, Carlos Martínez-Murillo, Rosalinda Sánchez-Arenas

“…Variations in levels of some adipokines, myokines, osteokines, hepatokines and inflammatory cytokines contribute to abnormal glucose and lipid metabolism. The aim of this study was to determine the pattern of adiponectin, osteocalcin (OCN), irisin, FGF-21, and MCP-1 according to the body size phenotype of middle-aged women, and their associations with BMI, visceral adipose tissue (VAT), and HOMA-IR. …”
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SVCT2 Overexpression and Ascorbic Acid Uptake Increase Cortical Neuron Differentiation, Which Is Dependent on Vitamin C Recycling between Neurons and Astrocytes by Katterine Salazar, Francisca Espinoza, Gustavo Cerda-Gallardo, Luciano Ferrada, Rocío Magdalena, Eder Ramírez, Viviana Ulloa, Natalia Saldivia, Ninoschka Troncoso, María José Oviedo, María José Barahona, Fernando Martínez, Francisco Nualart

“…The effect of WZB117, a selective glucose/DHA transporter 1 (GLUT1) inhibitor expressed in glial cells, was also studied. …”
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A Bioinspired Flexible Sensor for Electrochemical Probing of Dynamic Redox Disequilibrium in Cancer Cells by Zhongyuan Zeng, Jian Wang, Shuang Zhao, Yuchan Zhang, Jingchuan Fan, Hui Wu, Jiajia Chen, Zaikuan Zhang, Zexuan Meng, Lu Yang, Renzhi Wang, Bo Zhang, Guixue Wang, Chen‐Zhong Li, Guangchao Zang

“…Additionally, the intracellular redox disequilibrium and H2O2 release caused by DHA are positively correlated with the abundance and activity of glucose transporter 1 (GLUT1). In conclusion, this work has revealed the potential mechanism underlying the ability of AA to selectively kill tumor cells through the construction and use of PtNFs/CoPi@CC. …”
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Physical, Nutritional, and Bioactive Properties of Mandacaru Cladode Flour (<i>Cereus jamacaru</i> DC.): An Unconventional Food Plant from the Semi-Arid Brazilian Northeast by Ana Cristina S. Martins, Gracy Kelly V. de V. Medeiros, Jaielison Yandro P. da Silva, Vanessa B. Viera, Paternak de S. Barros, Marcos dos S. Lima, Marcelo S. da Silva, Josean F. Tavares, Yuri M. do Nascimento, Evandro F. da Silva, Juliana K. B. Soares, Evandro L. de Souza, Maria Elieidy G. de Oliveira

“…Using HPLC chromatography, glucose was identified as the predominant sugar (1.33 g/100 g), followed by four organic acids, especially malic acid (9.41 g/100 g) and citric acid (3.96 g/100 g). …”
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Walnut Prevents Cognitive Impairment by Regulating the Synaptic and Mitochondrial Dysfunction via JNK Signaling and Apoptosis Pathway in High-Fat Diet-Induced C57BL/6 Mice by Jong Hyun Moon, Jong Min Kim, Uk Lee, Jin Yong Kang, Min Ji Kim, Hyo Lim Lee, Hye Rin Jeong, Min Ji Go, Hyun-Jin Kim, Hye Won Park, Chul-Woo Kim, Sung Jin Park, Ho Jin Heo

“…To evaluate the neuro-protective effect of GC, 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), 2′,7′-dichlorodihydrofluorecein diacetate (DCF-DA) analysis were conducted in H₂O₂ and high glucose-induced neuronal PC12 cells and hippocampal HT22 cells. …”
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Association between growth differentiation factor 15 levels and gestational diabetes mellitus: A combined analysis by Yi-Cheng Lu, Yi-Cheng Lu, Song-Liang Liu, Yu-Shan Zhang, Fei Liang, Xiao-Yan Zhu, Xiao-Yan Zhu, Yue Xiao, Jing Wang, Cong Ding, Sudipta Banerjee, Jie-Yun Yin, Qiu-Ping Ma

“…ObjectiveGestational diabetes mellitus (GDM) is a common glucose metabolism disease occurs in pregnancy that affects both maternal and neonatal health. …”
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Effect of dihydroquercetin on the toxic properties of nickel nanoparticles by Ivan V. Gmoshinski, Mikhail A. Ananyan, Vladimir A. Shipelin, Nikolay A. Riger, Eleonora N. Trushina, Oksana K. Mustafina, Galina V. Guseva, Anastasya S. Balakina, Alexey I. Kolobanov, Sergey A. Khotimchenko, Dmitriy Yu. Ozherelkov

“…After the dihydroquercetin treatment, the group that consumed 53.7 nm nickel nanoparticles demonstrated lower blood serum glucose, triglycerides, low-density lipoprotein cholesterol, and creatinine. …”
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Increased Circulating Levels of Growth Differentiation Factor 15 in Association with Metabolic Disorders in People Living with HIV Receiving Combined Antiretroviral Therapy by Pere Domingo, María Gracia Mateo, Joan Villarroya, Rubén Cereijo, Ferran Torres, Joan C. Domingo, Laura Campderrós, José M. Gallego-Escuredo, María del Mar Gutierrez, Isabel Mur, Noemí Corbacho, Francesc Vidal, Francesc Villarroya, Marta Giralt

“…Correlations with lipids, glucose homeostasis, fat distribution, and CVR were explored. …”
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Functional Autoreactive Anti-β2 Adrenergic Antibodies May Contribute to Insulin Resistance Profile in Patients with Chronic Chagas Disease by Luz María Rodeles, Miguel Hernán Vicco, Álvaro Siano, Leonardo Andrés Fuchs, Luz María Peverengo, Silvia Sanchez Puch, Cora Beatriz Cymeryng, Iván Sergio Marcipar, Pablo Arias

“…This study aimed to determine the prevalence of anti-β2AR Abs in patients with CCD, as well as the correlation of these Abs with the presence of glucose and lipid metabolism disturbances, in order to explore their association with an insulin resistance profile. …”
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Sappanone a prevents diabetic kidney disease by inhibiting kidney inflammation and fibrosis via the NF-κB signaling pathway by Zhe Wang, Zhida Chen, Xinyi Wang, Yepeng Hu, Jing Kong, Jiabin Lai, Tiekun Li, Bibi Hu, Yikai Zhang, Xianan Zheng, Xiaoxian Liu, Shengyao Wang, Shengyao Wang, Shu Ye, Qiao Zhou, Chao Zheng, Chao Zheng

“…Similarly, in glomerular mesangial cells, SA pretreatment decreased high glucose (HG)-induced proliferation, inflammatory cytokines excretion, and fibrotic molecules expression. …”
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