Development and preclinical evaluation of multifunctional hydrogel for precise thermal protection during thermal ablation by Bowen Zheng, Peng Zhang, Qijun Lv, Tao Wu, Yadong Liu, Junjie Tang, Yanping Ma, Lili Cheng, Langtao Xu, Yizhen Wang, Yifan Xue, Jie Liu, Jie Ren

“…Therefore, an adjunctive thermoprotective hydrodissection technique with constant injection of 5% glucose (5% Glu) has currently been adopted for clinical application, but this may be hazardous to humans. …”
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Anti-Diabetic Activity of Glycyrrhetinic Acid Derivatives FC-114 and FC-122: Scale-Up, In Silico, In Vitro, and In Vivo Studies by Samuel Álvarez-Almazán, Luz Cassandra Solís-Domínguez, Paulina Duperou-Luna, Teresa Fuerte-Gómez, Martin González-Andrade, María E. Aranda-Barradas, Juan Francisco Palacios-Espinosa, Jaime Pérez-Villanueva, Félix Matadamas-Martínez, Susana Patricia Miranda-Castro, Crisóforo Mercado-Márquez, Francisco Cortés-Benítez

“…Results showed that both GA derivatives have potent PTP1B inhibitory activity being FC-122, a dual PTP1B/α-glucosidase inhibitor that could increase insulin sensitivity and reduce intestinal glucose absorption. Molecular docking, molecular dynamics, and enzymatic kinetics studies revealed the inhibition mechanism of FC-122 against α-glucosidase. …”
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Associations of fatty acids composition and estimated desaturase activities in erythrocyte phospholipids with biochemical and clinical indicators of cardiometabolic risk in non-dia... by Ivana Šarac, Jasmina Debeljak-Martačić, Marija Takić, Vuk Stevanović, Jelena Milešević, Milica Zeković, Tamara Popović, Jovica Jovanović, Nevena Kardum Vidović

“…Correlations were made with anthropometric, biochemical (serum glucose, triacylglycerols, LDL-C, HDL-C, ALT, AST, and their ratios) and clinical (blood pressure) indicators of cardiometabolic risk. …”
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Comparative Analysis of Clinical and Environmental Strains of Exophiala spinifera by Long-Reads Sequencing and RNAseq Reveal Adaptive Strategies by Yinggai Song, Yinggai Song, Yinggai Song, Minghao Du, Nickolas Menezes da Silva, Nickolas Menezes da Silva, Ence Yang, Vania A. Vicente, G. Sybren de Hoog, G. Sybren de Hoog, G. Sybren de Hoog, Ruoyu Li, Ruoyu Li, Ruoyu Li

“…Comparative transcriptome analysis demonstrated that 16 single-copy genes were significantly differentially expressed upon incubation in brain-heart infusion broth vs. Sabouraud glucose broth. Most of the single-copy genes upregulated with Brain Heart Infusion (BHI) were transporters. …”
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Weaker SARS-CoV-2 vaccine responses in nonalcoholic fatty liver disease with advanced liver fibrosis by David Hakimian, Johnny Amer, Alaa Jammal, Asher Shafrir, Yael Milgrom, Mohammad Masarowah, Wadi Hazou, Yuval Ishay, Ashraf Imam, Adi Francis, Abed Khalaileh, Rifaat Safadi

“…The strong response subgroup had lower metabolic comorbidities, including glucose hemostasis, hypertension, and dyslipidemia (p < 0.04). …”
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PACS-2 deficiency in tubular cells aggravates lipid-related kidney injury in diabetic kidney disease by Chanyue Zhao, Li Li, Chenrui Li, Chengyuan Tang, Juan Cai, Yu Liu, Jinfei Yang, Yiyun Xi, Ming Yang, Na Jiang, Yachun Han, Yan Liu, Shilu Luo, Li Xiao, Lin Sun

“…Transfection of HK2 cells with PACS-2 siRNA under high glucose plus palmitic acid (HGPA) condition aggravated lipid deposition and increased the expression of SOAT1 and sterol regulatory element-binding proteins (SREBPs), while the effect was blocked partially in that of co-transfection of SOAT1 siRNA. …”
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A Gender-, Age-, and Weight Status-Specific Analysis of the High Prevalence of Hyperuricemia Among Chinese Children and Adolescents with Obesity by Liu M, Cao B, Luo Q, Song Y, Shi Y, Cheng M, Liu K, Mao D, Wang X, Gong C

“…Multivariable logistic regression analyses showed that boy (OR=2.844, 95% CI 2.024– 3.998), age (OR=1.253, 95% CI 1.155– 1.360), BMI-Z score (OR=2.132, 95% CI 1.438– 3.162), fasting blood glucose (OR=0.907, 95% CI 0.860– 0.956), phosphorus (OR=4.123, 95% CI 2.349– 7.239), alkaline phosphatase (OR=1.002, 95% CI 1.001– 1.004), creatinine (OR=1.067, 95% CI 1.037– 1.098), urea nitrogen (OR=1.193, 95% CI 1.032– 1.378), aspartate aminotransferase (OR=1.016, 95% CI 1.002– 1.030), triglycerides (OR=1.339, 95% CI 1.075– 1.667), and high-density lipoprotein cholesterol (OR=0.381, 95% CI 0.160– 0.910) were independently associated with odds of HUA (P all< 0.05).Conclusion: The prevalence of HUA in Chinese obese children and adolescents is unexpectedly high. …”
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CORRELATION BETWEEN PULSE PRESSURE (MEAN VALUE OVER 24 HOURS) AND CHRONIC KIDNEY DISEASE IN HYPERTENSIVE PATIENTS by Alexandru Mincă, Maria Daniela Tănăsescu, Andra Elena Balcangiu-Stroescu, Alexandru Diaconescu, Delia Timofte, Ciprian Alexandru Boţocan, Laura Răducu, Dorin Dragoş, Dorin Ionescu, Mircea Nicolae Penescu

“…The aim of this study is to evaluate the presence / absence of the correlation between pulse pressure (PP, determined by ambulatory blood pressure monitoring (ABPM)) and traditional and non-traditional cardiovascular (CV) risk factors: age, sex, blood glucose, proteinuria / microalbuminuria, uric acid, ESR, fibrinogen, total cholesterol, HDL – cholesterol), triglyceridemia, Hb, in renal and non-renal hypertensive patients. …”
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Process quality of type 2 diabetes mellitus care and association with patient perceived attributes of family doctor service in urban general practices, Beijing, China by Feiyue Wang, Yun Wei, Meirong Wang, Zhaolu Pan, Guanghui Jin, Xiaoqin Lu

“…Regular follow up (p = 0.039), plasma blood glucose (p = 0.020), blood pressure (p = 0.026), body mass index (p = 0.044) and foot (p = 0.005) monitoring as well as each of the 6 health counseling indicators (all the p values < 0.05) were more likely to be received by patients when continuity of care was ensured. …”
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Glutamine Metabolism Supports the Functional Activity of Immune Cells against Aspergillus fumigatus by Daniela Antunes, Samuel M. Gonçalves, Vasiliki Matzaraki, Cláudia S. Rodrigues, Relber A. Gonçales, Joana Rocha, Jorge Sáiz, António Marques, Egídio Torrado, Ricardo Silvestre, Fernando Rodrigues, Frank L. van de Veerdonk, Coral Barbas, Mihai G. Netea, Vinod Kumar, Cristina Cunha, Agostinho Carvalho

“…ABSTRACT The reprogramming of cellular metabolism of immune cells is an essential process in the regulation of antifungal immune responses. In particular, glucose metabolism has been shown to be required for protective immunity against infection with Aspergillus fumigatus. …”
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Ancestral and environmental patterns in the association between triglycerides and other cardiometabolic risk factorsResearch in context by Karlijn A.C. Meeks, Amy R. Bentley, Charles Agyemang, Henrike Galenkamp, Bert-Jan H. van den Born, Nordin M.J. Hanssen, Ayo P. Doumatey, Adebowale A. Adeyemo, Charles N. Rotimi

“…We compared the strength of association between TG with hypertension, blood pressure, BMI, waist circumference, type 2 diabetes (T2D), and fasting glucose across West African (WA), East African (EA), and European (EU) ancestry populations residing in three vastly different environmental settings: sub-Saharan Africa, United States, and Europe. …”
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<i>Plasmodium knowlesi</i> (<i>Pk</i>) Malaria: A Review & Proposal of Therapeutically Rational Exchange (T-REX) of <i>Pk</i>-Resistant Red Blood Cells by Ryan Philip Jajosky, Shang-Chuen Wu, Philip G. Jajosky, Sean R. Stowell

“…When Fy(a-b-) RBC units are scarce (e.g., in Malaysia), clinicians can consider the risks and benefits of transfusing plausibly <i>Pk</i>-resistant RBCs, such as glucose-6-phosphate dehydrogenase deficient (G6PDd) RBCs and Southeast Asian ovalocytes (SAO). …”
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Higher magnesium levels are associated with better glycaemic control and diabetes remission post-bariatric surgery by Silva MM, Neves JS, Borges-Canha M, Mendes AP, Fonseca MJ, Mendonça F, Ferreira MJ, Salazar D, Pedro J, Guerreiro V, Lau E, Varela A, Freitas P, Carvalho D, CRIO group

“…Pre-BS, patients with Mg deficiency had poorer glycaemic control – HbA1c 7.2 ± 1.6% vs 6.4 ± 1.0% (p < 0.001), fasting plasma glucose 146.2 ± 58.8 mg/dL vs 117.5 ± 36.6 mg/dL (p < 0.001) and were under a greater number of anti-diabetic drugs 1.0 (IQR 0–2.0) vs 1.0 (IQR 0–1.0) (p = 0.002). …”
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Nutritional and Physicochemical Characteristics of Innovative High Energy and Protein Fruit- and Date-Based Bars by Hani A. Alfheeaid, Hassan Barakat, Sami A. Althwab, Khalid Hamid Musa, Dalia Malkova

“…Sugar profile analysis of the DBB and the FBB showed dependable changes based on date or fruit content. Fructose, glucose, and maltose contents were higher in the FBB than in the DBB, while sucrose content was higher in the DBB than in the FBB. …”
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Network meta-analysis on the effects of finerenone versus SGLT2 inhibitors and GLP-1 receptor agonists on cardiovascular and renal outcomes in patients with type 2 diabetes mellitu... by Yaofu Zhang, Li Jiang, Junheng Wang, Tongxin Wang, Chieh Chien, Weijun Huang, Xiaozhe Fu, Yonghua Xiao, Qiang Fu, Shidong Wang, Jinxi Zhao

“…Abstract Objective To evaluate the cardiovascular and renal benefits of finerenone, sodium-glucose cotransporter-2 inhibitors (SGLT2i) and glucagonlike peptide-1 receptor agonists (GLP-1 RA) in patients with Type 2 Diabetes Mellitus (T2DM) and chronic kidney disease (CKD) with network meta-analysis. …”
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Maintained imbalance of triglycerides, apolipoproteins, energy metabolites and cytokines in long-term COVID-19 syndrome patients by Georgy Berezhnoy, Rosi Bissinger, Anna Liu, Claire Cannet, Hartmut Schäfer, Katharina Kienzle, Michael Bitzer, Michael Bitzer, Helene Häberle, Siri Göpel, Christoph Trautwein, Yogesh Singh, Yogesh Singh, Yogesh Singh

“…Interestingly, LTCS and acute COVID-19 samples were distinguished mostly by their phenylalanine, 3-hydroxybutyrate (3-HB) and glucose concentrations, illustrating an imbalanced energy metabolism. …”
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Clinical Utility of Pepsin and Bile Acid in Tracheal Secretions for Accurate Diagnosis of Aspiration in ICU Patients by Dirk Bandorski, Khodr Tello, Harun Erdal, Janine Sommerlad, Jochen Wilhelm, Istvan Vadasz, Matthias Hecker, Dieter Walmrath, Werner Seeger, Ekaterina Krauss, Stefan Kuhnert

“…Pepsin levels were measured with an ELISA kit, while bile acid, uric acid, glucose, IL-6, and pH value in the tracheal secretion were analyzed using standardized lab methods. …”
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Study of relationships between taste receptor gene (<i>TAS1R2</i>) polymorphism rs4920566 and sugar sensitivity and food preference of sweet products by K. A. Frank, L. A. Gordeeva, E. N. Voronina, N. S. Velichkovich, E. A. Sokolova, E. G. Polenok, S. A. Mun, T. V. Tamarzina

“…Gender  was  a  significant  factor  affecting  the  taste  perception  of  the  sweetness  sugars  (maltose,  glucose,  sucrose and fructose) in students. Young  men more often than young  women  could  not distinguish  the taste of four sugars (β=-2.93(0.99), p=0.003). …”
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Interaction of Culture Medium and Artificial Light Type on Pigmentation of Micro-Propagated <i>Opuntia</i> Plants by Hector Silos Espino, R. Escalera García, D. Moncada González, Luis L. Valera-Montero, S. Flores Benítez, M. Ortiz Morales, H. S. Guzmán Maldonado, Nivia Escalante-Garcia, Ernesto Olvera-Gonzalez

“…Sequencing primer-amplified fragments for GT showed high similarity to uridine diphospho (UDP)-glucose from other species. This allows us to infer that it is possible to obtain products of high therapeutic value in the near future under controlled conditions.…”
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Machine learning‐based risk prediction of malignant arrhythmia in hospitalized patients with heart failure by Qi Wang, Bin Li, Kangyu Chen, Fei Yu, Hao Su, Kai Hu, Zhiquan Liu, Guohong Wu, Ji Yan, Guohai Su

“…Oral antiarrhythmic drug, left bundle branch block, serum magnesium, d‐dimer, and random blood glucose were significant predictors in half or more of the models. …”
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