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  1. 50921
  2. 50922

    The Tyrosine Phosphatase SHP2: A New Target for Insulin Resistance? by Céline Saint-Laurent, Laurène Mazeyrie, Mylène Tajan, Romain Paccoud, Isabelle Castan-Laurell, Philippe Valet, Thomas Edouard, Jean-Philippe Pradère, Cédric Dray, Armelle Yart

    Published 2022-08-01
    “…Many studies have documented that SHP2 modulation disrupted glucose homeostasis, pointing out a relationship between its dysfunction and insulin resistance, and the therapeutic potential of its targeting. …”
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  3. 50923

    Glycated hemoglobin level dynamics in COVID-19 survivors: 12 months follow-up study after discharge from hospital. by Marina Shestakova, Irina Kononenko, Zilya Kalmykovа, Tatyana Markova, Elena Kaplun, Mar'yana Lysenko, Natalya Mokrysheva

    Published 2022-01-01
    “…Patients were examined during the acute COVID-19 phase and in early (6-8 weeks) and late (52±2 weeks) periods after recovery. Oral glucose tolerance test was performed in the group with initial HbA1c > 6.0% to clarify the diagnosis.…”
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  4. 50924

    Critical Left Ventricular Ejection Fraction and Its Possible Pathogenesis in STEMI Patients with Supra-normal Ejection Fraction after Primary PCI by HAO Xiao, ZHAO Mei, LI Shuren

    Published 2022-02-01
    “…Data were collected, including baseline characteristics (gender, smoking history, drinking history, family history of cardiovascular disease, angina in the past one month, diabetes history, hypertension history, stroke history, old myocardial infarction, age, body mass index, pulse rate, and mean arterial pressure) , time of onset of chest pain〔including time from symptom onset to first medical contact, time from symptom onset to first antiplatelet therapy, time from symptom onset to first anticoagulation, symptom onset to balloon time (SBT) , door-to-balloon (D-to-B) time〕, periprocedural data 〔pre-procedural TIMI flow grade, collateral circulation, treatment of non-infarct related artery (NIRA) , thrombus aspiration, IABP application, anticoagulant medication, pre-procedural use of β-blockers, renin-angiotensin-aldosterone system inhibitors (RAASi) , or statins, intra-procedural application of tirofiban and prourokinase, post-procedure TIMI flow grade〕, laboratory test results (leukocyte count, Neutrophil count, lymphocyte count, hemoglobin, hematocrit, platelet count, potassium ion, urea nitrogen, creatinine, random blood glucose, eGFR, total cholesterol, triacylglycerol, high-density lipoprotein, low-density lipoprotein, very low-density lipoprotein, non-high density lipoprotein, creatine kinase, creatine kinase isozyme) and transthoracic echocardiographic data. …”
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  5. 50925
  6. 50926

    Serum folic acid: an effective indicator for arteriogenic erectile dysfunction by Xingliang Feng, Xingliang Feng, Yangyang Mei, Pinpeng Xie, Pinpeng Xie, Zhaoyu Xing, Zhaoyu Xing, Xiaogang Wang, Xiaogang Wang, Li Cui, Li Cui, Renfang Xu, Renfang Xu

    Published 2023-07-01
    “…There were no statistically significant inter-group differences on any basic parameters, including age, body mass index, fasting blood glucose, total cholesterol, and triglyceride. For further analysis, we divided the arteriogenic ED group into three subgroups by PSV range to compare serum FA levels among these subgroups. …”
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  7. 50927

    Effects of Pantothenic Acid Supplementation on Growth Performance, Carcass Traits, Plasma Parameters of Starter White Pekin Ducks Fed a Corn–Soybean Meal Diet by Jing Tang, Yongbao Wu, Bo Zhang, Zhiguo Qi, Dawei Luo, Jian Hu, Wei Huang, Zhengkui Zhou, Ming Xie, Shuisheng Hou

    Published 2021-09-01
    “…Among all ducks, the birds fed the basal diet with no supplementation of pantothenic acid had the lowest body weight, average daily weight gain (ADG), average daily feed intake (ADFI), breast meat yield, and plasma pantothenic acid and glucose contents (<i>p</i> < 0.05), and the greatest plasma UA content (<i>p</i> < 0.05). …”
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  8. 50928

    Hepatic Activin E mediates liver-adipose inter-organ communication, suppressing adipose lipolysis in response to elevated serum fatty acids by John D. Griffin, Joanne M. Buxton, Jeffrey A. Culver, Robert Barnes, Emily A. Jordan, Alexis R. White, Stephen E. Flaherty, Barbara Bernardo, Trenton Ross, Kendra K. Bence, Morris J. Birnbaum

    Published 2023-12-01
    “…Objective: The liver is a central regulator of energy metabolism exerting its influence both through intrinsic processing of substrates such as glucose and fatty acid as well as by secreting endocrine factors, known as hepatokines, which influence metabolism in peripheral tissues. …”
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  9. 50929

    Cadmium exposure causes transcriptomic dysregulation in adipose tissue and associated shifts in serum metabolites by Yi Zhu, Ping Cheng, Junxuan Peng, Sishuo Liu, Jie Xiang, Dandan Xu, Yuan Chen, Zhijian Chen, Xiaofeng Wang, Chi Luo, Peiwei Xu, Jinghao Sheng

    Published 2024-03-01
    “…Exposure to Cd can lead to various metabolic disturbances, notably disrupting glucose and lipid homeostasis. Despite this recognition, the direct impact of Cd exposure on lipid metabolism within adipose tissue, and the mechanisms underlying these effects, have not been fully elucidated. …”
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  10. 50930

    QIL1 mutation causes MICOS disassembly and early onset fatal mitochondrial encephalopathy with liver disease by Virginia Guarani, Claude Jardel, Dominique Chrétien, Anne Lombès, Paule Bénit, Clémence Labasse, Emmanuelle Lacène, Agnès Bourillon, Apolline Imbard, Jean-François Benoist, Imen Dorboz, Mylène Gilleron, Eric S Goetzman, Pauline Gaignard, Abdelhamid Slama, Monique Elmaleh-Bergès, Norma B Romero, Pierre Rustin, Hélène Ogier de Baulny, Joao A Paulo, J Wade Harper, Manuel Schiff

    Published 2016-09-01
    “…QIL1 absence in patients’ fibroblasts was associated with MICOS disassembly, abnormal cristae, mild cytochrome c oxidase defect, and sensitivity to glucose withdrawal. QIL1 expression rescued cristae defects, and promoted re-accumulation of MICOS subunits to facilitate MICOS assembly. …”
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  11. 50931

    Body Composition Parameters, Adiponectin, Leptin and Adiponectin/Leptin Ratio are Correlated with LH/FSH Ratio in Women with PCOS but not in Women without PCOS by Gita Pratama, Budi Wiweko, Asmarinah, Indah Suci Widyahening, Trinovita Andraini, Hartanto Bayuaji, Andon Hestiantoro

    Published 2024-01-01
    “…Body composition parameters, including body weight, body mass index (BMI), waist circumference (WC), waist to hip ratio (WHR), percent body fat (PBF), visceral fat area (VFA), percent subcutaneous fat (PSF) and skeletal muscle mass (SMM), were measured; levels of fasting glucose, fasting insulin, testosterone, and sex hormone binding globulin (SHBG) were measured; and homeostatic model assessment for insulin resistance (HOMA-IR) values, anti-Mullerian hormone (AMH), free androgen index (FAI), Ferriman-Gallwey (FG) score, adiponectin levels, leptin levels, adiponectin/leptin ratio, LH, FSH and LH/FSH ratio were measured. …”
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  12. 50932

    Central Role of Sibling Small RNAs NgncR_162 and NgncR_163 in Main Metabolic Pathways of Neisseria gonorrhoeae by Thomas Steiner, Marie Zachary, Susanne Bauer, Martin J. Müller, Markus Krischke, Sandra Radziej, Maximilian Klepsch, Bruno Huettel, Wolfgang Eisenreich, Thomas Rudel, Dagmar Beier

    Published 2023-02-01
    “…Indeed, these roles were confirmed by metabolomics and metabolic flux analysis, which revealed a bipartite metabolic network with glucose degradation for the supply of anabolic pathways and the usage of amino acids via the citric acid cycle for energy metabolism. …”
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  13. 50933

    Prediabetes Is Associated with Increased Prevalence of Sleep-Disordered Breathing by Enric Sánchez, Esther Sapiña-Beltrán, Ricard Gavaldà, Ferran Barbé, Gerard Torres, Ariadna Sauret, Mireia Dalmases, Carolina López-Cano, Liliana Gutiérrez-Carrasquilla, Marcelino Bermúdez-López, Elvira Fernández, Francisco Purroy, Eva Castro-Boqué, Cristina Farràs-Sallés, Reinald Pamplona, Dídac Mauricio, Cristina Hernández, Rafael Simó, Albert Lecube, on behalf of the ILERVAS Project Collaborators

    Published 2022-03-01
    “…A cross-sectional study conducted on 966 middle-aged subjects without known pulmonary disease (311 patients with prediabetes and 655 controls with normal glucose metabolism) was conducted. Prediabetes was defined by glycated hemoglobin (HbA1c), and a nonattended overnight home sleep study was performed. …”
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  14. 50934

    Management Strategies for Hyperglycemia Associated with the α-Selective PI3K Inhibitor Alpelisib for the Treatment of Breast Cancer by Tsvetalina Tankova, Elżbieta Senkus, Maria Beloyartseva, Simona Borštnar, Doina Catrinoiu, Mona Frolova, Alinta Hegmane, Andrej Janež, Mladen Krnić, Zoltan Lengyel, Yiola Marcou, Laura Mazilu, Bela Mrinakova, Ruth Percik, Katarina Petrakova, Gábor Rubovszky, Margarita Tokar, Eduard Vrdoljak

    Published 2022-03-01
    “…Lifestyle modifications, mainly comprising a reduced-carbohydrate diet, and a designated stepwise, personalized antihyperglycemic regimen, based on metformin, sodium–glucose co-transporter 2 inhibitors, and pioglitazone, are the main tools required to address the insulin-resistant hyperglycemia induced by alpelisib. …”
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  15. 50935

    Effect of the ratio of dietary metabolizable energy to nitrogen content on production performance, serum metabolites, rumen fermentation parameters, and bacterial diversity in yaks by Xiaojing Liu, Jie Li, Jie Li, Lizhuang Hao, Allan Degen, Dongyang Wang, Yonggui Ma, Jianzhang Niu, Yanfen Cheng, Yanfen Cheng, Shujie Liu

    Published 2022-10-01
    “…Group MY had higher ruminal NH3-N content than group HY and had a higher serum glucose content but lower urea content, lactate dehydrogenase, and creatine kinase content than group LY. …”
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  16. 50936

    Pasture-finishing of bison improves animal metabolic health and potential health-promoting compounds in meat by Stephan van Vliet, Amanda D. Blair, Lydia M. Hite, Jennifer Cloward, Robert E. Ward, Carter Kruse, Herman A. van Wietmarchsen, Nick van Eekeren, Scott L. Kronberg, Frederick D. Provenza

    Published 2023-04-01
    “…Relative to pasture-finished animals, the muscle of pen-finished animals displayed elevated glucose metabolites (~ 1.6-fold), triglycerides (~ 2-fold), markers of oxidative stress (~ 1.5-fold), and proteolysis (~ 1.2-fold). …”
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  17. 50937

    Leucine‐enriched whey protein supplementation, resistance‐based exercise, and cardiometabolic health in older adults: a randomized controlled trial by Ben Kirk, Kate Mooney, Sara Vogrin, Matthew Jackson, Gustavo Duque, Omid Khaiyat, Farzad Amirabdollahian

    Published 2021-12-01
    “…Outcome measures including arterial stiffness (pulse wave velocity), fasting plasma/serum biomarkers [glucose/glycated haemoglobin, total cholesterol, low‐density lipoprotein (LDL), high‐density lipoprotein, insulin, resistin, leptin, adiponectin, C‐reactive protein, tumour necrosis factor‐alpha, interleukin‐6, cystatin‐C, & ferritin], insulin resistance (HOMA‐IR), and kidney function (eGFR) were measured before and after intervention. …”
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  18. 50938

    Chemical Composition and Mechanism of Zuoci Pill in Treating Perimenopausal Hearing Loss Based on Network Pharmacology and Molecular Docking Technology by DIAO He, BAI Wenpei, ZHAO Lidong

    Published 2024-04-01
    “…Conclusion The 90 active ingredients in Zuoci pill, such as quercetin, act on 226 potential proteins such as AKT1 to regulate the antioxidant stress of tissues and cells, metabolism of blood lipids and glucose, and anti-tumor pathway, directly or indirectly protect the perimenopausal hearing function, IL-1&#x03B2; may be one of the key target proteins.…”
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  19. 50939

    Prediction of Type 2 Diabetic Nephropathy Based on BP Neural Network Optimized by Sparrow Search Algorithm by ZOU Qiong, WU Xi, ZHANG Yang, WAN Yi, CHEN Changsheng

    Published 2024-03-01
    “…Univariate analysis of risk factors for type 2 DN showed statistically significant for age, BMI, duration of diabetes, fasting blood glucose (FBG) , glycosylated hemoglobin (HbA1c) , low-density lipoprotein (LDL) , high-density lipoprotein (HDL) , triacylglycerol (TG) , systolic blood pressure (SBP) and diastolic blood pressure (DBP) (P&lt;0.05) . …”
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  20. 50940

    Association of stress hyperglycemia ratio and in-hospital mortality in patients with coronary artery disease: insights from a large cohort study by Wei Xu, Qirui Song, Xiang Wang, Zinan Zhao, Xuyang Meng, Chenxi Xia, Yibo Xie, Chenguang Yang, Ying Guo, Yatong Zhang, Fang Wang

    Published 2022-10-01
    “…Patients with an estimated glomerular filtration rate < 30 ml/min, cancer, or missing blood glucose/HbA1c data were excluded; therefore, 8,196 patients were included in the final analysis. …”
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