Untargeted Metabolomics Insights into Newborns with Congenital Zika Infection by Estéfane da C. Nunes, Ana M. B. de Filippis, Taiane do E. S. Pereira, Nieli R. da C. Faria, Álvaro Salgado, Cleiton S. Santos, Teresa C. P. X. Carvalho, Juan I. Calcagno, Flávia L. L. Chalhoub, David Brown, Marta Giovanetti, Luiz C. J. Alcantara, Fernanda K. Barreto, Isadora C. de Siqueira, Gisele A. B. Canuto

“…Significant alterations in essential and non-essential amino acids, as well as carbohydrates (including aldohexoses, such as glucose or mannose) and their derivatives (urea and pyruvic acid), were observed in the metabolic profiles analyzed. …”
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A Lead-Based Fragment Library Screening of the Glycosyltransferase WaaG from <i>Escherichia coli</i> by Federico Riu, Alessandro Ruda, Olof Engström, Claudio Muheim, Hani Mobarak, Jonas Ståhle, Paul Kosma, Antonio Carta, Daniel O. Daley, Göran Widmalm

“…In the presence of UDP-Glc²⁻, the best-docked pose of disaccharide <b>C4²⁻</b> is proximate to the glucose-binding site of WaaG. A study of the variation in angle and distance was performed on the different portions of WaaG (N-, the C- domains and the hinge region). …”
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<i>Bacillus subtilis</i>: As an Efficient Bacterial Strain for the Reclamation of Water Loaded with Textile Azo Dye, Orange II by Muhammad Ikram, Mohammad Naeem, Muhammad Zahoor, Marlia Mohd Hanafiah, Adeleke Abdulrahman Oyekanmi, Noor Ul Islam, Midrar Ullah, Mater H. Mahnashi, Amer Al Ali, Naif A. Jalal, Farkad Bantun, Aiman M. Momenah, Abdul Sadiq

“…To achieve maximum decolorization, the experimental conditions were optimized whereby maximum degradation was achieved at: a 25 ppm dye concentration, pH 7, a temperature of 35 °C, a 1000 mg/L concentration of glucose, a 1000 mg/L urea concentration, a 666.66 mg/L NaCl concentration, an incubation period of 3 days, and with hydroquinone as a redox mediator at a concentration of 66.66 mg/L. …”
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Mitigation of diabetes type II-induced nephropathy by ellagic acid nanoformulations: Amended glycemic control, oxidative stress, inflammation, and induced apoptosis by Steve Harakeh, Saber Hassan Saber, Nagla El-Shitany, Soad S. Ali, Turki Alamri, Mohammed W. Al-Rabia, Addisu Demeke Teklemariam, Kawther A. Zaher, Zeina W. Sharawi, Shafiul Haque, Manal Naseeb, Eram A. Albajri, Shaker Mousa

“…Additionally, EN and/or M effectively mitigated lipid peroxidation (LPO) levels in the affected kidneys, reduced fasting serum glucose, and lowered C-reactive protein (CRP) levels. …”
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Intracarotid Infusion of Redox-Active Manganese Porphyrin, MnTnBuOE-2-PyP⁵⁺, following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats by Xuan Li, Weina Duan, Li Du, Dongmei Chu, Peng Wang, Zhong Yang, Xingguang Qu, Zhenxing Yang, Ines Batinic-Haberle, Ivan Spasojevic, David S. Warner, James D. Crapo, Miriam M. Treggiari, Huaxin Sheng

“…All physiological parameters, including blood pressure, blood gas, glucose, and temperature, were well controlled during ischemia. …”
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Prostate cancer–Exercise and Metformin Trial (Pre-EMpT): study protocol for a feasibility factorial randomized controlled trial in men with localised or locally advanced prostate c... by Lucy McGeagh, Luke A. Robles, Raj Persad, Edward Rowe, Amit Bahl, Jonathan Aning, Anthony Koupparis, Paul Abrams, Claire Perks, Jeffrey Holly, Lyndsey Johnson, Constance Shiridzinomwa, Amarnath Challapalli, Ellie Shingler, Hilary Taylor, Jon Oxley, Meda Sandu, Richard M. Martin, J. Athene Lane

“…The Prostate cancer–Exercise and Metformin Trial examines that feasibility of randomising participants diagnosed with localised or locally advanced prostate cancer to interventions that modify physical activity and blood glucose levels. The primary outcomes are randomisation rates and adherence to the interventions over 6 months. …”
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Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma by Chin-Ho Tsao, Chin-Ho Tsao, Chin-Ho Tsao, Rong-Hong Jhou, Chien-Chih Ke, Chun-Wei Chang, Chi-Wei Chang, Bang-Hung Yang, Wen-Sheng Huang, Bing-Fu Shih, Ren-Shyan Liu, Ren-Shyan Liu, Ren-Shyan Liu, Ren-Shyan Liu, Ren-Shyan Liu

“…Because these two tracers revealed the lipogenic and glycolytic activity, respectively, which implies an antagonism between lipogenic metabolism and glucose metabolism in HCC. In addition, dual-tracer PET/CT not only revealed the lipogenic activity but also predicted the treatment response to lipogenesis-targeted therapy. …”
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Double diabetes as an effect modifier for adverse perinatal outcome in pregnant women with type 1 diabetes mellitus – a retrospective multicenter cohort study by Aneta Malinowska-Polubiec, Agnieszka Zawiejska, Ewa Romejko-Wolniewicz, Grzegorz Poprawski, Iwona Towpik, Jacek Brązert, Zuzanna Handziuk, Krzysztof Czajkowski

“…DDiab status was defined as T1DM plus pre-pregnancy obesity defined as BMI≥30 kg/m2 measured at the first antenatal visit (DDiabOb), or T1DM plus pre-pregnancy IR defined as eGDR (estimated Glucose Disposal Rate) below the 25th centile for the cohort measured at the first antenatal visit (DDiabIR). …”
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Impact of FAPI-46/dual-tracer PET/CT imaging on radiotherapeutic management in esophageal cancer by Simone Wegen, Karina Claus, Philipp Linde, Johannes Rosenbrock, Maike Trommer, Thomas Zander, Armin Tuchscherer, Christiane Bruns, Hans Anton Schlößer, Wolfgang Schröder, Marie-Lisa Eich, Thomas Fischer, Klaus Schomäcker, Alexander Drzezga, Carsten Kobe, Katrin Sabine Roth, Jasmin Josefine Weindler

“…In our analysis, we describe the impact of dual-tracer imaging with Gallium-68-radiolabeled inhibitors of FAP (FAPI-46-PET/CT) and fluorodeoxy-D-glucose (FDG-PET/CT) on the radiotherapeutic management of primary esophageal cancer (EC). …”
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Improving mental health in black men through a 24-week community-based lifestyle change intervention: the black impact program by Joshua J. Joseph, Timiya S. Nolan, Guy Brock, Amaris Williams, Songzhu Zhao, Alicia McKoy, Bjorn Kluwe, Faith Metlock, Katherine Campanelli, James B. Odei, Monique T. Khumalo, Dana Lavender, John Gregory, Darrell M. Gray

“…The change in cardiovascular health scores, defined as objective metrics of LS7 (LS5 [blood pressure, total cholesterol, fasting glucose, body mass index and smoking]), by baseline mental health were evaluated using linear mixed-effects models with an interaction term (time*baseline mental health variable) and a random intercept for each participant. …”
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Metabolic Effects of Gastrectomy and Duodenal Bypass in Early Gastric Cancer Patients with T2DM: A Prospective Single-Center Cohort Study by Young Ki Lee, Eun Kyung Lee, You Jin Lee, Bang Wool Eom, Hong Man Yoon, Young-Il Kim, Soo Jeong Cho, Jong Yeul Lee, Chan Gyoo Kim, Sun-Young Kong, Min Kyong Yoo, Yul Hwangbo, Young-Woo Kim, Il Ju Choi, Hak Jin Kim, Mi Hyang Kwak, Keun Won Ryu

“…Groups 1 and 2 showed a significant reduction in postprandial glucose (−97.9 and −67.8 mg/dL), body mass index (−2.1 and −2.3 kg/m²), and glycosylated hemoglobin (group 1 only, −0.5% point) (all <i>p</i> < 0.05). …”
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Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells by Zijian Fang, Shiqian Chen, Yusman Manchanda, Stavroula Bitsi, Philip Pickford, Alessia David, Maria M. Shchepinova, Ivan R. Corrêa Jr, David J. Hodson, Johannes Broichhagen, Edward W. Tate, Frank Reimann, Victoria Salem, Guy A. Rutter, Tricia Tan, Stephen R. Bloom, Alejandra Tomas, Ben Jones

“…The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of blood glucose homeostasis. Ligand-specific differences in membrane trafficking of the GLP-1R influence its signalling properties and therapeutic potential in type 2 diabetes. …”
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Course of pregnancy and delivery in women with the disorders of carbohydrate metabolism by E.V. Shaposhnikova, M.I. Bazina, M.M. Mentsik, E.V. Shageeva, T.A. Shageev

“…</i> </p> <p> <i><b>Keywords</b>: pregnancy, gestational diabetes, disorders of carbohydrate metabolism, glucose tolerance test, delivery, perinatal outcomes.…”
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Fungal Treatment for the Valorization of Technical Soda Lignin by Mariane Daou, Clementina Farfan Soto, Amel Majira, Laurent Cézard, Betty Cottyn, Florian Pion, David Navarro, Lydie Oliveira Correia, Elodie Drula, Eric Record, Sana Raouche, Stéphanie Baumberger, Craig B. Faulds

“…The three fungi could grow on the technical lignin alone, and the growth rate increased when the media were supplemented with glucose or maltose. The proteomic analysis of the culture supernatants after three days of growth revealed the secretion of numerous Carbohydrate-Active Enzymes (CAZymes). …”
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Fever-like temperature impacts on Staphylococcus aureus and Pseudomonas aeruginosa interaction, physiology, and virulence both in vitro and in vivo by E. C. Solar Venero, M. B. Galeano, A. Luqman, M. M. Ricardi, F. Serral, D. Fernandez Do Porto, S. A. Robaldi, B. A. Z. Ashari, T. H. Munif, D. E. Egoburo, S. Nemirovsky, J. Escalante, B. Nishimura, M. S. Ramirez, F. Götz, P. M. Tribelli

“…Altered metabolic features at 39 °C included arginine biosynthesis and the periplasmic glucose oxidation in S. aureus and P. aeruginosa monocultures respectively. …”
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Identification of angiogenesis-related genes in diabetic foot ulcer using machine learning algorithms by Xingkai Wang, Lei Meng, Juewei Zhang, Linxuan Zou, Zhuqiang Jia, Xin Han, Lin Zhao, Mingzhi Song, Zhen Zhang, Junwei Zong, Shouyu Wang, Ming Lu

“…Furthermore supporting this finding were the results of Western blot and real-time quantitative polymerase chain reaction (RT-qPCR), which showed decreased THBD expression in human umbilical vein endothelial cells (HUVECs) cultivated under high glucose. Conclusions: The findings implicate that THBD may influence DFU progression as a potential target for regulating angiogenesis, providing a valuable direction for future studies.…”
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Amoxicillin modulates gut microbiota to improve short-term high-fat diet induced pathophysiology in mice by Suresh Kumar, V. Samuel Raj, Ayaan Ahmad, Vikram Saini

“…The short course of amoxicillin treatment to HFD-fed mice resulted in beneficial effects by significantly reducing fasting blood glucose and skewing the number of thrombocytes towards a normal range. …”
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Autophagosomes Defeat Ferroptosis by Decreasing Generation and Increasing Discharge of Free Fe2+ in Skin Repair Cells to Accelerate Diabetic Wound Healing by Shengnan Cui, Xi Liu, Yong Liu, Wenzhi Hu, Kui Ma, Qilin Huang, Ziqiang Chu, Lige Tian, Sheng Meng, Jianlong Su, Wenhua Zhang, Haihong Li, Xiaobing Fu, Cuiping Zhang

“…Here, it is hypothesized that SAPs derived from human umbilical vein endothelial cells (HUVECs) can restore the function of skin repair cells by inhibiting ferroptosis to promote diabetic wound healing. High glucose (HG)‐caused ferroptosis in human dermal fibroblasts (HDFs) is observed in vitro, which results in impaired cellular function. …”
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Exogenous mitochondrial transplantation improves survival and neurological outcomes after resuscitation from cardiac arrest by Kei Hayashida, Ryosuke Takegawa, Yusuke Endo, Tai Yin, Rishabh C. Choudhary, Tomoaki Aoki, Mitsuaki Nishikimi, Atsushi Murao, Eriko Nakamura, Muhammad Shoaib, Cyrus Kuschner, Santiago J. Miyara, Junhwan Kim, Koichiro Shinozaki, Ping Wang, Lance B. Becker

“…The beneficial effects on survival were associated with improvements in rapid recovery of arterial lactate and glucose levels, cerebral microcirculation, lung edema, and neurological function. …”
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Cellulase hyper-production by Trichoderma reesei mutant SEU-7 on lactose by Chengcheng Li, Fengming Lin, Le Zhou, Lei Qin, Bingzhi Li, Zhihua Zhou, Mingjie Jin, Zhan Chen

“…However, until now the induction efficiency of most soluble carbon sources, especially lactose and glucose, is still inferior to cellulose despite extensive efforts have been made by either optimizing the fermentation process or constructing the recombinant strains. …”
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