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50961
Untargeted Metabolomics Insights into Newborns with Congenital Zika Infection
Published 2021-04-01“…Significant alterations in essential and non-essential amino acids, as well as carbohydrates (including aldohexoses, such as glucose or mannose) and their derivatives (urea and pyruvic acid), were observed in the metabolic profiles analyzed. …”
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50962
A Lead-Based Fragment Library Screening of the Glycosyltransferase WaaG from <i>Escherichia coli</i>
Published 2022-02-01“…In the presence of UDP-Glc<sup>2−</sup>, the best-docked pose of disaccharide <b>C4<sup>2−</sup></b> is proximate to the glucose-binding site of WaaG. A study of the variation in angle and distance was performed on the different portions of WaaG (N-, the C- domains and the hinge region). …”
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50963
<i>Bacillus subtilis</i>: As an Efficient Bacterial Strain for the Reclamation of Water Loaded with Textile Azo Dye, Orange II
Published 2022-09-01“…To achieve maximum decolorization, the experimental conditions were optimized whereby maximum degradation was achieved at: a 25 ppm dye concentration, pH 7, a temperature of 35 °C, a 1000 mg/L concentration of glucose, a 1000 mg/L urea concentration, a 666.66 mg/L NaCl concentration, an incubation period of 3 days, and with hydroquinone as a redox mediator at a concentration of 66.66 mg/L. …”
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50964
Mitigation of diabetes type II-induced nephropathy by ellagic acid nanoformulations: Amended glycemic control, oxidative stress, inflammation, and induced apoptosis
Published 2023-10-01“…Additionally, EN and/or M effectively mitigated lipid peroxidation (LPO) levels in the affected kidneys, reduced fasting serum glucose, and lowered C-reactive protein (CRP) levels. …”
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50965
Intracarotid Infusion of Redox-Active Manganese Porphyrin, MnTnBuOE-2-PyP<sup>5+</sup>, following Reperfusion Improves Long-Term, 28-Day Post-Stroke Outcomes in Rats
Published 2023-10-01“…All physiological parameters, including blood pressure, blood gas, glucose, and temperature, were well controlled during ischemia. …”
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50966
Prostate cancer–Exercise and Metformin Trial (Pre-EMpT): study protocol for a feasibility factorial randomized controlled trial in men with localised or locally advanced prostate c...
Published 2022-08-01“…The Prostate cancer–Exercise and Metformin Trial examines that feasibility of randomising participants diagnosed with localised or locally advanced prostate cancer to interventions that modify physical activity and blood glucose levels. The primary outcomes are randomisation rates and adherence to the interventions over 6 months. …”
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50967
Dual-tracer positron emission tomography/computed tomography as an imaging probe of de novo lipogenesis in preclinical models of hepatocellular carcinoma
Published 2022-09-01“…Because these two tracers revealed the lipogenic and glycolytic activity, respectively, which implies an antagonism between lipogenic metabolism and glucose metabolism in HCC. In addition, dual-tracer PET/CT not only revealed the lipogenic activity but also predicted the treatment response to lipogenesis-targeted therapy. …”
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50968
Double diabetes as an effect modifier for adverse perinatal outcome in pregnant women with type 1 diabetes mellitus – a retrospective multicenter cohort study
Published 2023-07-01“…DDiab status was defined as T1DM plus pre-pregnancy obesity defined as BMI≥30 kg/m2 measured at the first antenatal visit (DDiabOb), or T1DM plus pre-pregnancy IR defined as eGDR (estimated Glucose Disposal Rate) below the 25th centile for the cohort measured at the first antenatal visit (DDiabIR). …”
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50969
Impact of FAPI-46/dual-tracer PET/CT imaging on radiotherapeutic management in esophageal cancer
Published 2024-04-01“…In our analysis, we describe the impact of dual-tracer imaging with Gallium-68-radiolabeled inhibitors of FAP (FAPI-46-PET/CT) and fluorodeoxy-D-glucose (FDG-PET/CT) on the radiotherapeutic management of primary esophageal cancer (EC). …”
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50970
Improving mental health in black men through a 24-week community-based lifestyle change intervention: the black impact program
Published 2024-01-01“…The change in cardiovascular health scores, defined as objective metrics of LS7 (LS5 [blood pressure, total cholesterol, fasting glucose, body mass index and smoking]), by baseline mental health were evaluated using linear mixed-effects models with an interaction term (time*baseline mental health variable) and a random intercept for each participant. …”
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50971
Metabolic Effects of Gastrectomy and Duodenal Bypass in Early Gastric Cancer Patients with T2DM: A Prospective Single-Center Cohort Study
Published 2021-09-01“…Groups 1 and 2 showed a significant reduction in postprandial glucose (−97.9 and −67.8 mg/dL), body mass index (−2.1 and −2.3 kg/m<sup>2</sup>), and glycosylated hemoglobin (group 1 only, −0.5% point) (all <i>p</i> < 0.05). …”
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50972
Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells
Published 2020-11-01“…The glucagon-like peptide-1 receptor (GLP-1R) is an important regulator of blood glucose homeostasis. Ligand-specific differences in membrane trafficking of the GLP-1R influence its signalling properties and therapeutic potential in type 2 diabetes. …”
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50973
Course of pregnancy and delivery in women with the disorders of carbohydrate metabolism
Published 2020-09-01“…</i> </p> <p> <i><b>Keywords</b>: pregnancy, gestational diabetes, disorders of carbohydrate metabolism, glucose tolerance test, delivery, perinatal outcomes.…”
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50974
Fungal Treatment for the Valorization of Technical Soda Lignin
Published 2021-01-01“…The three fungi could grow on the technical lignin alone, and the growth rate increased when the media were supplemented with glucose or maltose. The proteomic analysis of the culture supernatants after three days of growth revealed the secretion of numerous Carbohydrate-Active Enzymes (CAZymes). …”
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50975
Fever-like temperature impacts on Staphylococcus aureus and Pseudomonas aeruginosa interaction, physiology, and virulence both in vitro and in vivo
Published 2024-02-01“…Altered metabolic features at 39 °C included arginine biosynthesis and the periplasmic glucose oxidation in S. aureus and P. aeruginosa monocultures respectively. …”
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50976
Identification of angiogenesis-related genes in diabetic foot ulcer using machine learning algorithms
Published 2023-12-01“…Furthermore supporting this finding were the results of Western blot and real-time quantitative polymerase chain reaction (RT-qPCR), which showed decreased THBD expression in human umbilical vein endothelial cells (HUVECs) cultivated under high glucose. Conclusions: The findings implicate that THBD may influence DFU progression as a potential target for regulating angiogenesis, providing a valuable direction for future studies.…”
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50977
Amoxicillin modulates gut microbiota to improve short-term high-fat diet induced pathophysiology in mice
Published 2022-10-01“…The short course of amoxicillin treatment to HFD-fed mice resulted in beneficial effects by significantly reducing fasting blood glucose and skewing the number of thrombocytes towards a normal range. …”
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50978
Autophagosomes Defeat Ferroptosis by Decreasing Generation and Increasing Discharge of Free Fe2+ in Skin Repair Cells to Accelerate Diabetic Wound Healing
Published 2023-09-01“…Here, it is hypothesized that SAPs derived from human umbilical vein endothelial cells (HUVECs) can restore the function of skin repair cells by inhibiting ferroptosis to promote diabetic wound healing. High glucose (HG)‐caused ferroptosis in human dermal fibroblasts (HDFs) is observed in vitro, which results in impaired cellular function. …”
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50979
Exogenous mitochondrial transplantation improves survival and neurological outcomes after resuscitation from cardiac arrest
Published 2023-03-01“…The beneficial effects on survival were associated with improvements in rapid recovery of arterial lactate and glucose levels, cerebral microcirculation, lung edema, and neurological function. …”
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50980
Cellulase hyper-production by Trichoderma reesei mutant SEU-7 on lactose
Published 2017-10-01“…However, until now the induction efficiency of most soluble carbon sources, especially lactose and glucose, is still inferior to cellulose despite extensive efforts have been made by either optimizing the fermentation process or constructing the recombinant strains. …”
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