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51021
Efficacy of celecoxib add-on treatment for immuno-metabolic depression: Protocol of the INFLAMED double-blind placebo-controlled randomized controlled trial
Published 2023-02-01“…Explorative analyses will be performed on the role of CRP, IL-6, TNF-α, cholesterol, triglycerides, glucose, BMI, waist and hip circumference. Ethics and dissemination: This protocol has been approved by the Medical Ethics Review Board of the Amsterdam UMC, location VUmc (2022.0015) on 2-6-2022, as well as by the competent authority in The Netherlands: CCMO, on 3-8-2022. …”
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51022
Characterization of Fruit Development, Antioxidant Capacity, and Potential Vasoprotective Action of Peumo (<i>Cryptocarya alba</i>), a Native Fruit of Chile
Published 2021-12-01“…Also, the assay of isolated rat aorta with endothelium-dependent relaxation damage demonstrated that the peumo extract induced vascular protection, depending on its concentration under a high glucose condition. These results demonstrate that these endemic fruits have a good chance as ingredients or foods with functional properties.…”
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51023
Coronary inflammation based on pericoronary adipose tissue attenuation in type 2 diabetic mellitus: effect of diabetes management
Published 2024-03-01“…Abstract Background Coronary inflammation plays crucial role in type 2 diabetes mellitus (T2DM) induced cardiovascular complications. Both glucose-lowering drug interventions (GLDIS) and glycemic control (GC) status potentially correlate coronary inflammation, as indicated by changes in pericoronary adipose tissue (PCAT) attenuation, and thus influence cardiovascular risk. …”
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51024
<sup>1</sup>H-NMR-Based Metabolomics in Autism Spectrum Disorder and Pediatric Acute-Onset Neuropsychiatric Syndrome
Published 2022-11-01“…In supervised models, the metabolomic profile of ASD was significantly different from controls (<i>p</i> = 0.0001), with skewed concentrations of asparagine, aspartate, betaine, glycine, lactate, glucose, and pyruvate. Metabolomic separation was also observed between PANS and ASD subjects (<i>p</i> = 0.02), with differences in the concentrations of arginine, aspartate, betaine, choline, creatine phosphate, glycine, pyruvate, and tryptophan. …”
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51025
Identifying the Metabolic Signatures of PPARD-Overexpressing Gastric Tumors
Published 2022-01-01“…As the PPARD mice aged from 10 weeks to 35 weeks and 55 weeks, we observed significant changes in levels of the metabolites inosine monophosphate (<i>p</i> = 0.0054), adenosine monophosphate (<i>p</i> = 0.009), UDP-glucose (<i>p</i> = 0.0006), and oxypurinol (<i>p</i> = 0.039). …”
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51026
Mechanisms of Dihuang (Rehmanniae Radix) in treating diabetic nephropathy complicated with depression based on network pharmacology
Published 2022-06-01“…Conclusion: Based on network parmacology, this study preliminarily predict the effects of Dihuang (Rehmanniae Radix) in treating DN complicated with depression by regulating inflammation, glucose metabolism, nution nerve, etc.…”
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51027
Untargeted Plasma Metabolomics Unravels a Metabolic Signature for Tissue Sensitivity to Glucocorticoids in Healthy Subjects: Its Implications in Dietary Planning for a Healthy Life...
Published 2021-06-01“…These results, combined with a higher glucose, sorbitol, and lactate abundance, suggest a higher Cori cycle, polyol pathway, and inter-tissue one-carbon metabolism rate and a lower fat mobilization rate at the fasting state in the most sensitive compared to the most resistant group. …”
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51028
In Silico-Based Design and In Vivo Evaluation of an Anthranilic Acid Derivative as a Multitarget Drug in a Diet-Induced Metabolic Syndrome Model
Published 2021-09-01“…It was evaluated in a diet-induced MetS rat model and simultaneously lowered blood pressure, glucose, total cholesterol, and triglyceride levels after a 14-day treatment. …”
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51029
Initial indicators for the prognosis of Acinetobacter Baumannii bacteremia in children
Published 2023-09-01“…However, CRP (p = 0.000) and blood glucose(p = 0.036) were significantly higher in the death group than those in the survival group. …”
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51030
Associations of antidiabetic drugs with diabetic retinopathy in people with type 2 diabetes: an umbrella review and meta-analysis
Published 2024-01-01“…This study was registered with PROSPERO (CRD42022332052).ResultsWith trial evidence from 11 systematic reviews and meta-analyses, we found that the use of glucagon-like peptide-1 receptor agonists (GLP-1 RA), sodium-glucose cotransporter-2 inhibitors (SGLT-2i), or dipeptidyl peptidase-4 inhibitors (DPP-4i) was not statistically associated with the risk of DR, compared to either placebo (RR: GLP-1 RA, 0.98, 0.89-1.08; SGLT-2i, 1.00, 95% CI 0.79-1.27; DPP-4i, 1.17, 0.99-1.39) or other antidiabetic drugs. …”
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51031
Phenolic Constituents from <i>Wendlandia tinctoria</i> var. <i>grandis</i> (Roxb.) DC. Stem Deciphering Pharmacological Potentials against Oxidation, Hyperglycemia, and Diarrhea: P...
Published 2022-09-01“…Furthermore, the computational modeling study supported the current in vitro and in vivo findings, and the isolated constituents had a higher or comparable binding affinity for glutathione reductase and urase oxidase enzymes, glucose transporter 3 (GLUT 3), and kappa-opioid receptor, inferring potential antioxidant, hypoglycemic, and antidiarrheal properties, respectively. …”
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51032
Supplementation of feed and water after long-duration road transportation: The effects on welfare and rumen fermentation in goats
Published 2023-03-01“…TRT0 and TRT1 goats had POST plasma glucose concentrations above their PRE values (p < 0.05). …”
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51033
Comparing the differences of physicochemical properties and volatiles in semi-dry Hakka rice wine and traditional sweet rice wine via HPLC, GC–MS and E-tongue analysis
Published 2023-12-01“…The total sugar (16.13 mg/mL) of semi-dry HRW was significantly lower than that of TSRW (135.79 mg/mL), especially the trehalose, glucose, sucrose and maltose. Its alcohol content was significantly higher than that of TSRW. …”
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51034
Cardiomyocyte infection by Trypanosoma cruzi promotes innate immune response and glycolysis activation
Published 2023-02-01“…Using gene editing and pharmacological inhibitors, we found that T. cruzi uptake was mediated in part by the glucose-facilitated transporter GLUT4 and that the attenuation of glycolysis, HIF-1α activation, or GLUT4 expression decreased T. cruzi infection. …”
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51035
使用基础胰岛素治疗成人2型糖尿病:亚太地区循证临床实践指南
Published 2023-06-01“…Abstract The objective of this study was to provide recommendations regarding effectiveness, safety, optimal starting dose, optimal maintenance dose range, and target fasting plasma glucose of five basal insulins (glargine U‐300, degludec U‐100, glargine U‐100, detemir, and insulin protamine Hagedorn) in insulin‐naïve adult patients with type 2 diabetes in the Asia‐Pacific region. …”
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51036
فرط سكر الدم عند القبول و الاختلاطات ضمن المشفى عند مرضى احتشاء العضلة القلبية الحاد مع ارتفاع قطعة ST ....
Published 2019-04-01“…Patients were classified according to their admission blood glucose into two groups , the first group was admission hyperglycemia (defined ≥ 200 mg/dl) , whereas the second group was without admission hyperglycemia , to assess its impact on In-hospital complications (Acute heart failure , Cardiogenic shock , Bleeding ). …”
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51037
Dietary Antioxidants, Quality of Nutrition and Cardiovascular Characteristics among Omnivores, Flexitarians and Vegetarians in Poland—The Results of Multicenter National Representa...
Published 2023-01-01“…In women, vegetarians had substantially lower BMI than omnivores (<i>p</i> < 0.05) and flexitarians (<i>p</i> < 0.05) and a lower mean serum glucose compared with omnivores (<i>p</i> < 0.01) and flexitarians (<i>p</i> < 0.05). …”
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51038
Diagnostic milk biomarkers for predicting the metabolic health status of dairy cattle during early lactation
Published 2023-01-01“…Blood metabolic parameters included β-hydroxybutyrate (BHB), nonesterified fatty acids, glucose, insulin-like growth factor-1 (IGF-1) and insulin. …”
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51039
A multi-center study on glucometabolic response to bariatric surgery for different subtypes of obesity
Published 2022-11-01“…Still, the bariatric surgery significantly reduced their blood glucose (median HbA1c decreased by 27.2%). The hypermetabolic obesity-hyperinsulinemia (HMO-I) group was characterized by severe insulin resistance and high incidence of hyperinsulinemia (87.8%) pre-surgery, which had been greatly alleviated post-surgery. …”
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51040
The Expression of Two Distinct Sets of Glycolytic Enzymes Reveals Differential Effects of Glycolytic Reprogramming on Pancreatic Ductal Tumorigenesis in Mice
Published 2023-11-01“…Pancreatic ductal adenocarcinoma (PDAC) is associated with enhanced aerobic glycolysis through elevated glucose uptake and the upregulated expression of genes encoding rate-limiting glycolytic enzymes. …”
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