Growth and Biochemical Composition Characteristics of <i>Arthrospira platensis</i> Induced by Simultaneous Nitrogen Deficiency and Seawater-Supplemented Medium in an Outdoor Racewa... by Hualian Wu, Tao Li, Jinting Lv, Zishuo Chen, Jiayi Wu, Na Wang, Houbo Wu, Wenzhou Xiang

“…On the contrary, a profound reduction was observed in protein, lipid, and pigment contents. Glucose, the main monosaccharide in the <i>A. platensis</i> biomass, increased from 77.81% to 93.75% of total monosaccharides. …”
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Circulating circular RNA profiles associated with celiac disease seropositivity in children with type 1 diabetes by Juan-juan Zhang, Jun-qi Wang, Xu Xu, Li-dan Zhang, Cai-ping Zhang, Wen-li Lu, Wei-qiong Gu, Zhi-ya Dong, Yuan Xiao, Zhen-wei Xia

“…Data on clinical characteristics (i.e., blood glucose control, residual islet function, and daily insulin dosage) and immunophenotypes (i.e., islet autoantibodies and immune cell subsets) were collected.ResultsIn total, 35.0% of patients were positive for CDAbs. …”
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Analysis of the relationship between the gut microbiota enterotypes and colorectal adenoma by Miwei Lv, Miwei Lv, Miwei Lv, Jiawei Zhang, Jiawei Zhang, Jiaxin Deng, Jiaxin Deng, Jiancong Hu, Jiancong Hu, Qinghua Zhong, Qinghua Zhong, Mingli Su, Mingli Su, Dezheng Lin, Dezheng Lin, Tian Xu, Xuhao Bai, Juan Li, Juan Li, Xuefeng Guo, Xuefeng Guo

“…Logistic regression analysis showed that Prevotella enterotype was an independent risk factor for colorectal adenoma.DiscussionThe Prevotella enterotype may increase the occurrence of colorectal adenoma through inflammatory association and interference with glucose and lipid metabolism in human body. In conclusion, the differences we observed between different enterotypes add a new potential factor to the development of colorectal adenoma.…”
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SYSTEMI - systemic organ communication in STEMI: design and rationale of a cohort study of patients with ST-segment elevation myocardial infarction by Florian Bönner, Christian Jung, Amin Polzin, Ralf Erkens, Lisa Dannenberg, Rojda Ipek, Madlen Kaldirim, Mareike Cramer, Patricia Wischmann, Oana-Patricia Zaharia, Christian Meyer, Ulrich Flögel, Bodo Levkau, Axel Gödecke, Jens Fischer, Nicolaj Klöcker, Martina Krüger, Michael Roden, Malte Kelm

“…Systemic metabolism will be approached by serial liquid biopsies and analysed with respect to glucose and lipid metabolism as well as oxygen transport. …”
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Randomized controlled trial for time-restricted eating in overweight and obese young adults by Li-min Zhang, Zhan Liu, Jia-qi Wang, Rui-qiang Li, Jing-yi Ren, Xian Gao, Shuai-shuai Lv, Lu-yao Liang, Fan Zhang, Bo-wen Yin, Yan Sun, Hao Tian, Hui-chen Zhu, Yu-tian Zhou, Yu-xia Ma

“…Compared with control, 6-h eTRE reduced systolic blood pressure, mean glucose, fasting insulin, insulin resistance, leptin, and thyroid axis activity, whereas lTRE only reduced leptin. …”
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Maternal Folic Acid Supplementation Differently Affects the Small Intestinal Phenotype and Gene Expression of Newborn Lambs from Differing Litter Sizes by Zhen Li, Bo Wang, Heqiong Li, Luyang Jian, Hailing Luo, Bing Wang, Can Zhang, Xingang Zhao, Ying Xue, Sijia Peng, Shuxian Zuo

“…Meanwhile, the expression levels of insulin-like growth factor I (<i>IGF-I</i>), B-cell lymphoma-2 (<i>BCL-2)</i> and sodium/glucose co-transporter-1 (<i>SGLT1</i>) in the small intestines of the newborn lambs were increased, while the opposite was true for Bcl2-associated × (<i>BAX)</i> in response to FA supplementation (<i>p</i> < 0.05). …”
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MTHFR Gene Polymorphisms and Cardiovascular Risk Factors, Clinical-Imagistic Features and Outcome in Cerebral Venous Sinus Thrombosis by Anca Elena Gogu, Dragos Catalin Jianu, Victor Dumitrascu, Horia Ples, Alina Zorina Stroe, Daniel Docu Axelerad, Any Docu Axelerad

“…The protocol included demographic (age, sex), clinical, neuroimagistic features, paraclinic (genetic polymorphism of <i>MTHFR</i>, factor V <i>G1691A</i>—Leiden, prothrombin <i>G20210A</i>, PAI-1 <i>675 4G/5G</i>; Homocysteine level, the lipid profile, blood glucose and Glycohemoglobin HbA1c, high- sensitive C- reactive protein- hsCRP) data, as well as treatment and outcome. …”
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A pilot study of contrast-enhanced electrical impedance tomography for real-time imaging of cerebral perfusion by Yuyan Zhang, Yuyan Zhang, Yuyan Zhang, Jian’an Ye, Jian’an Ye, Yang Jiao, Weirui Zhang, Weirui Zhang, Tao Zhang, Tao Zhang, Xiang Tian, Xiang Tian, Xuetao Shi, Xuetao Shi, Feng Fu, Feng Fu, Liang Wang, Canhua Xu, Canhua Xu

“…Both of groups were injected with glucose, an electrical impedance-enhanced contrast agent, through the right internal carotid artery under EIT monitoring. …”
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Quality of life in the course of a one-year use of an advanced hybrid closed-loop system in adults with type 1 diabetes previously naïve to advanced diabetes technology by Katarzyna Cyranka, Katarzyna Cyranka, Katarzyna Cyranka, Bartłomiej Matejko, Bartłomiej Matejko, Anna Juza, Anna Juza, Beata Kieć-Wilk, Beata Kieć-Wilk, Ohad Cohen, Maciej T. Malecki, Maciej T. Malecki, Tomasz Klupa, Tomasz Klupa

“…At month 6 of the study, patients were switched from the sensor GS3 (Continuous Glucose Monitoring) system, powered by Guardian™ Sensor 3) to GS4. …”
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Relationship between retinal microvascular impairment and subclinical atherosclerosis in SLE by Paola Conigliaro, Massimo Cesareo, Maria Sole Chimenti, Carlo Nucci, Raffaele Mancino, Sara Ferrigno, Stefano Rizza, Susanna Longo, Carolina Nesi, Federico Carlucci, Alberto Bergamini, Massimo Federici

“…Patients with SLE showed higher triglycerides (p=0.019), Triglycerides-Glucose (TyG) Index (p=0.035), ACC/AHA guidelines (p=0.001), Framingham Risk Scores (p=0.008) and a reduced superficial (p&lt;0.001) and deep (p=0.005) whole retinal vessel density (VD) compared with HCs.In SLE univariate analysis, deep whole VD showed a negative correlation with IMT (p=0.027), age (p=0.001), systolic blood pressure (p=0.011), QRISK3 Score (p&lt;0.001), Systemic Lupus International Collaborating Clinics Damage Index (p=0.006) and apolipoprotein B (p=0.021), while a positive correlation was found with female sex (p=0.029). …”
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The relationship between different exercise conditions and pericoronary inflammation as quantified by coronary CTA in coronary artery disease by Huaze Xi, Mengyuan Jing, Qiu Sun, Yuanyuan Wang, Hao Zhu, Junlin Zhou

“…Sex (P = 0.016; odds ratio [OR]: 0.673), high-density lipoprotein (P = 0.006; OR: 0.601), low-density lipoprotein (P = 0.001; OR. 0.762), hypertension (P = 0.000; OR: 0.762), smoking (P = 0.005; OR: 0.670), and postprandial glucose (P = 0.030; OR: 0.812), household income (P = 0.038; OR:1.117), and body mass index (P = 0.000; OR:1.084) were the risk factors for elevated RCA-FAI values in the patients with coronary artery disease group. …”
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Ozone therapy: protocol for treating canine parvovirus infection by Tiago Gonçalves dos Santos, Jéssica Rodrigues Orlandin, Matheus Ferreira de Almeida, Rodrigo Ferreira Scassiotti, Vanessa Cristina Oliveira, Sarah Ingrid Pinto Santos, Vitória Mattos Pereira, Priscilla Avelino Ferreira Pinto, Clésio Gomes Mariano Junior, Carlos Eduardo Ambrósio

“…Before treatment and after 24 and 48 hours, the following clinical signs were evaluated: episodes of emesis and diarrhea, weight, hydration, blood glucose level, abdominal pain, and blood count. One control group animal died within the first hours of hospitalization. …”
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Efficacy and Safety of Low-dose Oral Prednisolone for Patients with Refractory Hunner-type Interstitial Cystitis by Yoshiyuki Akiyama, Aya Niimi, Akira Nomiya, Satoru Taguchi, Yuta Yamada, Yusuke Sato, Daisuke Yamada, Daichi Maeda, Tetsuo Ushiku, Haruki Kume, Yukio Homma

“…No patients discontinued treatment due to adverse events, although hypertension and glucose intolerance occurred in two patients, but these were resolved by temporal medications. …”
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A2DS2 Score Combined With Clinical and Neuroimaging Factors Better Predicts Stroke-Associated Pneumonia in Hyperacute Cerebral Infarction by Yaoyao Yu, Tianyi Xia, Zhouli Tan, Huwei Xia, Shenping He, Han Sun, Xifan Wang, Haolan Song, Weijian Chen

“…Therefore, we combined these variables into a new SAP prediction model with the C-statistic of 0.84 (95% CI: 0.78–0.90). Fasting plasma glucose (OR = 1.404; 95% CI: 1.202–1.640; P &lt; 0.001), NIHSS score (OR = 1.088; 95% CI: 1.010–1.172; P = 0.026), previous stroke (OR = 4.333; 95% CI: 1.645–11.418; P = 0.003), SAP (OR = 3.420; 95% CI: 1.332–8.787; P = 0.011), basal ganglia-dilated perivascular spaces (BG-dPVS) (OR = 2.124; 95% CI: 1.313–3.436; P = 0.002), and core infarct volume (OR = 1.680; 95% CI: 1.166–2.420; P = 0.005) were independently associated with poor outcome. …”
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Evaluation of miRNA-143 and miRNA-145 Expression and Their Association with Vitamin-D Status Among Obese and Non-Obese Type-2 Diabetic Patients by Aladel A, Khatoon F, Khan MI, Alsheweir A, Almutairi MG, Almutairi SO, Almutairi FK, Osmonaliev K, Beg MMA

“…A positive correlation was observed between miRNA-143 and miRNA-145 expression and decreased vitamin-D status in T2DM had significant association with impaired blood glucose fasting (p=0.001) and HDL level (p< 0.0001). …”
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β-Hydroxybutyrate inhibits apoptosis in bovine neutrophils through activating ERK1/2 and AKT signaling pathways by Yuxiang Song, Kexin Wang, Juan J. Loor, Qianming Jiang, Yuchen Yang, Shang Jiang, Siyuan Liu, Jiyuan He, Xiancheng Feng, Xiliang Du, Lin Lei, Wenwen Gao, Guowen Liu, Xinwei Li

“…Neutrophils were isolated from 5 multiparous cows (within 3 wk postpartum) with serum BHB concentrations <0.6 mM and glucose concentrations >3.5 mM. In a series of experiments, neutrophils were treated with increasing concentrations of BHB (0, 0.6, 2, and 3 mM for 10 h) and time (0, 2, 4, 6, 8, and 10 h with 2 mM). …”
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The Effects of Nano-Curcumin Supplementation on Risk Factors for Cardiovascular Disease: A GRADE-Assessed Systematic Review and Meta-Analysis of Clinical Trials by Damoon Ashtary-Larky, Mahnaz Rezaei Kelishadi, Reza Bagheri, Seyedeh Parisa Moosavian, Alexei Wong, Sayed Hossein Davoodi, Pardis Khalili, Frédéric Dutheil, Katsuhiko Suzuki, Omid Asbaghi

“…According to the results of this study, nano-curcumin supplementation was associated with improvements in the glycemic profile by decreasing fasting blood glucose (FBG) (WMD: −18.14 mg/dL; 95% CI: −29.31 to −6.97; <i>p</i> = 0.001), insulin (WMD: −1.21 mg/dL; 95% CI: −1.43 to −1.00; <i>p</i> < 0.001), and HOMA-IR (WMD: −0.28 mg/dL; 95% CI: −0.33 to −0.23; <i>p</i> < 0.001). …”
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Discovery of Novel DPP-IV Inhibitors as Potential Candidates for the Treatment of Type 2 <i>Diabetes Mellitus</i> Predicted by 3D QSAR Pharmacophore Models, Molecular Docking and <... by Azizullo Musoev, Sodik Numonov, Zhuhong You, Hongwei Gao

“…Dipeptidyl peptidase-IV (DPP-IV) rapidly breaks down the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP). Thus, the use of DPP-IV inhibitors to retard the degradation of endogenous GLP-1 is a possible mode of therapy correcting the defect in incretin-related physiology. …”
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Association between body mass index and chronic metabolic diseases in Chinese aged population by JIANG Ying, LI Qingyao, CHEN Zhiqi, WANG Jialu, LI Yun, XU Renying

“…Systolic blood pressure ≥140 mmHg (1 mmHg=0.133 kPa), diastolic blood pressure ≥90 mmHg, or self-reported hypertension history was defined as hypertension. Fasting blood glucose ≥7.0 mmol/L or self-reported history of diabetes was defined as diabetes. …”
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Probiotics for the Treatment of Docetaxel-Related Weight Gain of Breast Cancer Patients—A Single-Center, Randomized, Double-Blind, and Placebo-Controlled Trial by Zhang Juan, Zhang Qing, Liang Yongping, Liyuan Qian, Wei Wu, Yanguang Wen, Jianbin Tong, Jianbin Tong, Jianbin Tong, Boni Ding

“…The primary outcome: the changes in body weight and body-fat percentage of the patients were measured by a designated physician using a fat analyzer, and the secondary outcomes: the fasting insulin, plasma glucose, and lipids were directly obtained from the Hospital Information System (HIS); The metabolites were measured using liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS); The fecal microbiome was analyzed using bacterial 16S ribosomal RNA (rRNA) gene sequence. …”
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