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51281
The effect of dietary carbohydrate and calorie restriction on weight and metabolic health in overweight/obese individuals: a multi-center randomized controlled trial
Published 2023-05-01“…Serum triglycerides were significantly reduced in the LC + CR diet group compared with the LC or CR diet alone. Plasma glucose, homeostasis model assessment of insulin resistance, and cholesterol concentrations (total, LDL, and HDL) did not change significantly between the groups during the 12-week intervention. …”
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51282
Evaluating the correlation of sclerostin levels with obesity and type 2 diabetes in a multiethnic population living in Kuwait
Published 2024-04-01“…Furthermore, SOST levels showed a significant positive correlation with gender, age, waist circumference, systolic and diastolic blood pressure, fasting blood glucose, HbA1c, insulin, total cholesterol, triglycerides, HDL, LDL, ALT, and AST (p-Value ≥0.05). …”
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51283
Enhancing Metabolic Efficiency through Optimizing Metabolizable Protein Profile in a Time Progressive Manner with Weaned Goats as a Model: Involvement of Gut Microbiota
Published 2022-04-01“…Here, using weaned goats as a model, we report that animals adapted to high rumen-undegradable protein diet in a dynamic manner by enriching fecal community that could effectively move toward and scavenge nutrients such as glucose and amino acids and, thereafter, elicit butyrate and BCAA production. …”
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51284
Cumulative Lactation and Clinical Metabolic Outcomes at Mid-Life among Women with a History of Gestational Diabetes
Published 2022-02-01“…Using data from the Diabetes & Women’s Health Study (2012–2014; <i>n</i> = 577), a longitudinal cohort of women with past GDM from the Danish National Birth Cohort (1996–2002), we assessed associations of cumulative lactation duration (none, <6 months, 6–12 months, ≥12–24 months, and ≥24 months) with clinical metabolic outcomes (including type 2 diabetes [T2D], prediabetes, and obesity) and cardiometabolic biomarkers (including biomarkers of glucose/insulin metabolism, fasting lipids, inflammation, and anthropometrics) 9–16 years after enrollment when women were at mid-life. …”
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51285
Chemical Characterization and Immunomodulatory Activity of Fucoidan from <i>Sargassum hemiphyllum</i>
Published 2022-12-01“…The SHF, with a molecular weight of 1166.48 kDa (44.06%, <i>w</i>/<i>w</i>), consisted of glucose (32.68%, <i>w</i>/<i>w</i>), galactose (24.81%, <i>w</i>/<i>w</i>), fucose (20.75%, <i>w</i>/<i>w</i>), xylose (6.98%, <i>w</i>/<i>w</i>), mannose (2.76%, <i>w</i>/<i>w</i>), other neutral monosaccharides, and three uronic acids, including glucuronic acid (5.39%, <i>w</i>/<i>w</i>), mannuronic acid (1.76%, <i>w</i>/<i>w</i>), and guronuronic acid (1.76%, <i>w</i>/<i>w</i>). …”
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51286
Melatonin ameliorates serobiochemical alterations and restores the cardio-nephro diabetic vascular and cellular alterations in streptozotocin-induced diabetic rats
Published 2023-03-01“…The serum biochemical analysis of diabetic STZ rats showed a significant (P < 0.05) increase in the concentrations of blood glucose, total oxidative capacity (TOC), CK-MB, endothelin-1, myoglobin, H-FABP, ALT, AST, urea, and creatinine as compared to control rats. …”
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51287
A Novel Sulfated Glycoprotein Elicitor Extracted from the Moroccan Green Seaweed <i>Codium decorticatum</i> Induces Natural Defenses in Tomato
Published 2022-04-01“…The AGB and AGP extracts contained 37.67% and 48.38% of the total carbohydrates, respectively, and were mainly composed of galactose, glucose, arabinose, and a minor amount of xylose and rhamnose. …”
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51288
Clinical Features of Non-Alcoholic Fatty Liver Disease in the Non-Lean Population
Published 2023-05-01“…Patients in the obesity group had a significantly lower level of gamma-glutamyl transpeptidase, higher levels of platelet, glucose, prothrombin time, and more common of moderate to severe inflammatory activity when compared to those in the overweight group. …”
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51289
Diabetes Mellitus in Prader-Willi Syndrome: Natural History during the Transition from Childhood to Adulthood in a Cohort of 39 Patients
Published 2021-11-01“…These results underline the need for early identification of patients at risk, prevention of obesity, and repeated blood glucose monitoring during the transition period.…”
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51290
Effects of PPM1K rs1440581 and rs7678928 on serum branched-chain amino acid levels and risk of cardiovascular disease
Published 2021-01-01“…Lifestyle intervention had little influence on the serum levels of fasting plasma glucose (FPG), TG, HDL-c, alanine aminotransferase (ALT), AST and creatinine (CREA) in subjects with rs1440581 CC genotype or rs7678928 TT genotype (p> .05). …”
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51291
Real-World Treatment Patterns according to Clinical Practice Guidelines in Patients with Type 2 Diabetes Mellitus and Established Cardiovascular Disease in Korea: Multicenter, Retr...
Published 2024-03-01“…Background Recent diabetes management guidelines recommend that sodium-glucose cotransporter 2 inhibitors (SGLT2is) or glucagon-like peptide 1 receptor agonists (GLP-1RAs) with proven cardiovascular benefits should be prioritized for combination therapy in patients with type 2 diabetes mellitus (T2DM) and established cardiovascular disease (CVD). …”
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51292
Metabolic risk in schoolchildren is associated with low levels of cardiorespiratory fitness, obesity, and parents’ nutritional profile
Published 2016-07-01“…The metabolic risk profile was calculated by summing the standardized values of high density lipoproteins and low density lipoproteins, triglycerides, glucose and systolic blood pressure. The parents’ nutritional status was evaluated by self-reported weight and height data, for body mass index calculating. …”
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51293
Therapeutic mechanism of baicalein in peritoneal dialysis-associated peritoneal fibrosis based on network pharmacology and experimental validation
Published 2023-05-01“…Importantly, using a mouse model of peritoneal fibrosis by intraperitoneally injecting 4.25% glucose dialysate, we found that baicalein treatment significantly attenuated peritoneal fibrosis, as evident by decreased collagen deposition, protein expression of α-SMA and fibronectin, and peritoneal thickness, at least, by reducing the expression of MMP2, suggesting that baicalein may have therapeutic potential in suppressing peritoneal dialysis-related fibrosis.…”
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51294
Predicting hypertension by obesity- and lipid-related indices in mid-aged and elderly Chinese: a nationwide cohort study from the China Health and Retirement Longitudinal Study
Published 2023-04-01“…We examined 13 obesity- and lipid-related indices, including waist circumference (WC), body mass index (BMI), waist-height ratio (WHtR), visceral adiposity index (VAI), a body shape index (ABSI), body roundness index (BRI), lipid accumulation product index (LAP), conicity index (CI), Chinese visceral adiposity index (CVAI), triglyceride-glucose index (TyG-index) and their combined indices (TyG-BMI, TyG-WC, TyG-WHtR). …”
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51295
The F-actin modifier villin regulates insulin granule dynamics and exocytosis downstream of islet cell autoantigen 512
Published 2016-08-01“…Moreover, in cells depleted either of villin or Ica512 F-actin cages restraining cortical SGs were enlarged, basal secretion was increased while glucose-stimulated insulin release was blunted. The latter changes were reverted by overexpressing villin in Ica512-depleted cells, but not vice versa. …”
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51296
Dietary N-carbamylglutamate and L-arginine supplementation improves redox status and suppresses apoptosis in the colon of intrauterine growth-retarded suckling lambs
Published 2022-12-01“…Both mRNA and protein levels of C/EBP homologous protein 10 (CHOP10), B-cell lymphoma/leukaemia 2 (Bcl-2) -associated X protein (Bax), apoptosis antigen 1 (Fas), activating transcription factor 6 (ATF6), caspase 3, and glucose-regulated protein 78 (GRP78) were lower (P < 0.05) while glutathione peroxidase 1 (GPx1), Bcl-2 and catalase (CAT) levels were higher (P < 0.05) in colonic tissue for IUGR + Arg and IUGR + NCG lambs compared with IUGR lambs. …”
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51297
Is exercise a medicine or a vaccine adjuvant? A Look at Obesity and Covid-19
Published 2022-09-01“…These include reducing the incidence of a number of different cancers, lowering the risk of excessive weight gain (along with related health problems as well as diabetes), and improving cardiovascular health (as well as reducing the risk of high blood pressure in addition to heart stroke) (Ghardashi-Afousi et al., 2018).The acute effect of exercise has been shown to lead to a transient decrease in triglyceride levels, an increase in HDL cholesterol levels, a decrease in blood pressure, a decrease in insulin resistance, and an improvement in glucose control. Regular exercise increases blood flow and oxygen to the brain which improves memory and mental function. …”
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51298
Prevalence of Hyperuricemia and Its Correlation with Cardiometabolic Index in Xinjiang Region
Published 2024-03-01“…In the comparison between the HUA group and non-HUA group, there was no statistically significant difference in stroke history and HDL-C levels (P>0.05) ; the differences in gender, age, ethnicity, history of coronary heart disease, hypertension and diabetes, diastolic blood pressure (DBP) , systolic blood pressure (SBP) , urea nitrogen (UN) , blood uric acid (SUA) , creatinine, fasting plasma glucose (FPG) , triacylglycerol (TG) , total cholesterol (TC) , low-density lipoprotein cholesterol (LDL-C) , BMI, waist-to-height ratio (WHtR) , and CMI were statistically significant (P<0.05) . …”
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51299
RFX6 facilitates aerobic glycolysis‐mediated growth and metastasis of hepatocellular carcinoma through targeting PGAM1
Published 2023-12-01“…Abstract Background Hepatocellular carcinoma (HCC) cells undergo reprogramming of glucose metabolism to support uncontrolled proliferation, of which the intrinsic mechanism still merits further investigation. …”
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51300
Corni Fructus extracts ameliorate Streptozotocin-Induced diabetes in mice via regulating AMPK/ACC/CPT-1 signaling pathway
Published 2023-08-01“…The results showed that CF can inhibit the body weight loss, decrease blood glucose and regulate serum lipid contents in T2DM mice. …”
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