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51441
Characterization and Process Optimization for Enhanced Production of Polyhydroxybutyrate (PHB)-Based Biodegradable Polymer from <i>Bacillus flexus</i> Isolated from Municipal Solid...
Published 2023-03-01“…The highest PHB production by <i>B. flexus</i> was obtained after 48 h of incubation (3.9 g/L) at pH 7.0 (3.7 g/L), 35 °C (3.5 g/L) with glucose (4.1 g/L) and peptone (3.4 g/L) as carbon and nitrogen sources, respectively. …”
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51442
Targeting YAP1‐regulated Glycolysis in Fibroblast‐Like Synoviocytes Impairs Macrophage Infiltration to Ameliorate Diabetic Osteoarthritis Progression
Published 2024-02-01“…In addition, the yes‐associated protein 1 (YAP1)/thioredoxin‐interacting protein (TXNIP) signaling axis is demonstrated to play a crucial role in regulating glucose transporter 1 (GLUT1)‐dependent glycolysis in FLSs, thereby controlling the expression of a series of adhesion molecules such as intercellular adhesion molecule‐1 (ICAM‐1) which may subsequently fine‐tune the infiltration of M1‐polarized synovial macrophages in DOA patients and db/db diabetic OA mice. …”
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51443
Radiological Findings Increased the Successful of COVID-19 Diagnosis in Hospitalized Patients Suspected of Respiratory Viral Infection but with a Negative First SARS-CoV-2 RT-PCR R...
Published 2022-03-01“…There were differences between the groups in the platelet count and the levels of D-dimer, procalcitonin, and glucose (<i>p</i> < 0.05). Chest CT scans categorized as COVID-19 Reporting and Data System 5 (CO-RADS 5) were more frequent in the COVID-19 group than in the control group (91.7% vs. 52.6%; <i>p</i> = 0.003). …”
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51444
Simultaneously Screening for Liver Steatosis and Fibrosis in Romanian Type 2 Diabetes Mellitus Patients Using Vibration-Controlled Transient Elastography with Controlled Attenuatio...
Published 2022-07-01“…In multivariate analyses, BMI (β = 0.349, <i>p</i> < 0.001), fasting plasma glucose (β = 0.211, <i>p</i> = 0.006), and triglycerides (β = 0.132, <i>p</i> = 0.044) were predictors of S3. …”
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51445
Prognostic effect of stress hyperglycemia ratio on patients with severe aortic stenosis receiving transcatheter aortic valve replacement: a prospective cohort study
Published 2024-02-01“…The formula used to determine SHR was as follows: admission blood glucose (mmol/L)/(1.59×HbA1c[%]–2.59). The primary endpoint was defined as all-cause mortality, while secondary endpoints included a composite of cardiovascular mortality or readmission for heart failure, and major adverse cardiovascular events (MACE) including cardiovascular mortality, non-fatal myocardial infarction, and non-fatal stroke. …”
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51446
Mulberry leaf extract improves non-specific immunity and antioxidant capacity of largemouth bass (Micropterus salmoides) fed a high-starch diet
Published 2022-11-01“…Plasma C3 levels in the MLE3, MLE4, and MLE5 groups were significantly higher than those in the HSD group. In addition, glucose (GLU) levels in the MLE3, MLE4, and MLE5 groups were significantly lower than those in the HSD group. …”
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51447
Taohong siwu decoction attenuates AIM2 and NLRC4 inflammasomes by ameliorates deoxyribonucleic acid damage after ischemic stroke
Published 2022-08-01“…Therefore, we constructed an IS model (I/R) in rats and performed oxygen-glucose deprivation/reoxygenation (OGD/R) on BV2 cells. …”
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51448
Epidemic Status, Disease Burden and Prediction of Cardiovascular Diseases in China, 1990-2019
Published 2024-01-01“…Risk factors associated with death from cardiovascular diseases mainly included smoking, second-hand smoke, alcohol consumption, low physical activity, high fasting blood glucose, high systolic blood pressure, high BMI, high low density lipoprotein cholesterol and renal insufficiency. …”
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51449
The use of progeroid DNA repair-deficient mice for assessing anti-aging compounds, illustrating the benefits of nicotinamide riboside
Published 2022-10-01“…Here, we further utilize the short lifespan and early onset of signs of neurological degeneration in Ercc1Δ/− and Xpg−/− mice to test compounds that influence nutrient sensing (metformin, acarbose, resveratrol), inflammation (aspirin, ibuprofen), mitochondrial processes (idebenone, sodium nitrate, dichloroacetate), glucose homeostasis (trehalose, GlcNAc) and nicotinamide adenine dinucleotide (NAD+) metabolism. …”
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51450
Untargeted stable isotope-resolved metabolomics to assess the effect of PI3Kβ inhibition on metabolic pathway activities in a PTEN null breast cancer cell line
Published 2022-10-01“…Cells were fed with [U-13C] glucose and treated for 1, 3, 6, and 24 h with 0.5 µM AZD8186 or vehicle, extracted by an optimized sample preparation protocol and analyzed by LC-QTOF-MS. …”
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51451
Pyridyl Methylsulfinyl Benzimidazole Derivatives as Promising Agents against <i>Giardia lamblia</i> and <i>Trichomonas vaginalis</i>
Published 2022-12-01“…Here, we tested five synthesized benzimidazole derivatives as possible drugs for treating giardiasis and trichomoniasis, probing the bifunctional enzyme glucose 6-phosphate dehydrogenase::6-phosphogluconolactone from <i>G. lamblia</i> (GlG6PD::6PGL) and <i>T. vaginalis</i> (TvG6PD::6PGL) as a drug target. …”
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51452
<i>Cannabis sativa</i> L. Inflorescences from Monoecious Cultivars Grown in Central Italy: An Untargeted Chemical Characterization from Early Flowering to Ripening
Published 2020-04-01“…Citric acid, malic acid and glucose showed the highest content in the late flowering period, whereas the content of proline drastically decreased after June in all cultivars. …”
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51453
A case report of anti-GAD65 antibody-positive autoimmune encephalitis in children associated with autoimmune polyendocrine syndrome type-II and literature review
Published 2023-11-01“…At presentation, he had uncontrolled blood glucose levels with elevated HbA1c levels. Additionally, the serum and CSF autoantibodies were positive against the anti-GAD65 antibody with the titer of 1:100 and 1:32 respectively. …”
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51454
The Impact of Decaffeinated Green Tea Extract on Fat Oxidation, Body Composition and Cardio-Metabolic Health in Overweight, Recreationally Active Individuals
Published 2021-02-01“…Fat oxidation (‘FAT<sub>MAX</sub>’ and steady state exercise protocols), body composition, cardio-metabolic and blood measures (serum glucose, insulin, leptin, adiponectin, glycerol, free fatty acids, total cholesterol, high [HDL-c] and low-density lipoprotein cholesterol [LDL-c], triglycerides, liver enzymes and bilirubin) were assessed at baseline, week 4 and 8. …”
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51455
Puerarin Inhibits NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis via P2X7 Receptor in Cardiomyocytes and Macrophages
Published 2023-08-01“…Additionally, we employed D-glucose-induced H9C2 rat cardiomyocytes and lipopolysaccharide-treated RAW264.7 mouse mononuclear macrophages as the in vitro model on DCM research, which is close to the pathological conditions. …”
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51456
Development and optimization of vildagliptin solid lipid nanoparticles loaded ocuserts for controlled ocular delivery: A promising approach towards treating diabetic retinopathy
Published 2024-06-01“…VLD-SLNPs-OCUs might benefit retinal microvascular blood flow beyond blood glucose control and may be considered a promising approach to treating diabetic retinopathy.…”
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51457
Intrauterine Growth Restriction Affects Colonic Barrier Function <i>via</i> Regulating the Nrf2/Keap1 and TLR4-NF-κB/ERK Pathways and Altering Colonic Microbiome and Metabolome Hom...
Published 2024-02-01“…IUGR altered the concentrations of plasma glucose, total protein, triglycerides, and cholesterol. …”
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51458
ANÁLISIS DE RESISTENCIA INSULÍNICA, TOLERANCIA A LA GLUCOSA Y TESTOSTERONA EN MUJERES JÓVENES CON SÍNDROME DE OVARIO POLIQUÍSTICO AGRUPADAS POR ÍNDICE DE MASA CORPORAL
Published 2006-01-01“…Total testosterone, 2-h oral glucose tolerance test (OGTT), and body mass index (BMI) were performed in all patients. …”
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51459
Regulation of Fungal Morphogenesis and Pathogenicity of <i>Aspergillus flavus</i> by Hexokinase AfHxk1 through Its Domain Hexokinase_2
Published 2023-11-01“…Hexokinase AfHxk1 is a critical enzyme in fungal glucose metabolism. However, the role of AfHxk1 in <i>A. flavus</i> development, aflatoxin biosynthesis, and virulence has not yet been explored. …”
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51460
油茶蒲纯化多糖的制备与组分、结构分析Preparation and component, structure analysis of purified polysaccharides from Camellia oleifera fruit hull
Published 2023-04-01“…The monosaccharide composition of the purified polysaccharide of Camellia oleifera fruit hull was fucose 0.64%, arabinose 7.68%, galactose 3.74%, glucose 76.43%, xylose 2.77%, mannose 1.60%, galacturonic acid 5.34%, glucuronic acid 1.33%, and mannuronic acid 0.47%. …”
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