血清低密度脂蛋白胆固醇浓度与糖尿病风险之间的关联: 一项前瞻性队列研究 by Jiaojiao Huang, Hong Lin, Shuangyuan Wang, Mian Li, Tiange Wang, Zhiyun Zhao, Yu Xu, Min Xu, Jieli Lu, Yuhong Chen, Guang Ning, Weiqing Wang, Yufang Bi, Long Wang

“…A standard 75‐g oral glucose tolerance test was conducted at baseline and follow‐up visits to diagnose diabetes. …”
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Dietary <span style="font-variant: small-caps">l</span>-carnitine Supplementation Modifies the Lipopolysaccharide-Induced Acute Phase Reaction in Dairy Cows by Jennifer Meyer, Susanne Ursula Kononov, Sandra Grindler, Johanna Tröscher-Mußotter, Mohamad Taher Alaedin, Jana Frahm, Liane Hüther, Jeannette Kluess, Susanne Kersten, Dirk von Soosten, Ulrich Meyer, Erika Most, Klaus Eder, Helga Sauerwein, Jana Seifert, Korinna Huber, Anja Wegerich, Jürgen Rehage, Sven Dänicke

“…Group CAR maintained a higher insulin level compared to group CON even up to 72 h pi which might support glucose utilization following an APR.…”
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Protective effect of metformin on the retina of type 2 diabetic rats and its regulation on serum cystatin C by Hui-Ling Bai, Xiao-Yan Zhu, Qin Liu, Yan-Ying Zhang, Wan-Rong Kang, Shu Zhang

“…After 3mo of intervention, fasting blood glucose(FBG)and fasting serum insulin(FINS)indexes of the three groups were measured respectively, and the homeostasis model assessment of insulin resistance(HOMA-IR)was calculated and analyzed; The serum Cys C, tumor necrosis factor-α(TNF-α), the levels of Interleukin-8(IL-8), vascular endothelial growth factor(VEGF)and reactive oxygen species(ROS)were measured, and we observed the retinal tissue and vascular morphology of rats by FFA, HE staining and transmission electron microscopy; rats in metformin intervention group B began to give metformin by gavage 3mo after the course of T2DM, and other rats were given normal saline. …”
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Neonatal outcomes according to different therapies for gestational diabetes mellitus by Amanda L. da Silva, Augusto R. do Amaral, Daniela S. de Oliveira, Lisiane Martins, Mariana R. e Silva, Jean Carl Silva

“…The study included women aged at least 18 years, with a singleton pregnancy, who met the criteria for gestational diabetes mellitus. Blood glucose levels, fetal abdominal circumference, body mass index and gestational age were considered for treatment decision-making. …”
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Phenolic Content, Antioxidant, Antibacterial, Antihyperglycemic, and α-Amylase Inhibitory Activities of Aqueous Extract of <i>Salvia lavandulifolia</i> Vahl by Firdaous Remok, Soukaina Saidi, Aman Allah Gourich, Khalid Zibouh, Mohamed Maouloua, Fadwa El Makhoukhi, Naoual El Menyiy, Hanane Touijer, Mohamed Bouhrim, Sevser Sahpaz, Ahmad Mohammad Salamatullah, Mohammed Bourhia, Touriya Zair

“…Finally, the inhibitory effect of the α-amylase enzyme as well as the antihyperglycaemic effect was evaluated in vivo in normal rats overloaded with starch or D-glucose. The aqueous extract obtained by use of the decoction of leaves of <i>S. lavandulifolia</i> contains 246.51 ± 1.69 mg EQ of gallic acid/g DE, 23.80 ± 0.12 mg EQ quercetin/g DE, and 2.46 ± 0.08 mg EQ catechin /g DE. …”
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Relationship between the level of serum SUA and CysC and diabetic retinopathy in patients with type 2 diabetes mellitus by Kun Cheng, Jin-Feng Xie, Gang-Xue Tang, Qian-Wei Huang, Sheng Huang

“…The levels of fasting plasma glucose(FPG), hemoglobin Alc(HbA1c), SUA and CysC in control group, T2DM group, NPDR group and PDR group were gradually increased(all P&#x0026;#x003C;0.001). …”
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Brazilian green propolis improves gut microbiota dysbiosis and protects against sarcopenic obesity by Takuro Okamura, Masahide Hamaguchi, Ryo Bamba, Hanako Nakajima, Yuta Yoshimura, Tomonori Kimura, Yoshitaka Hashimoto, Saori Majima, Takafumi Senmaru, Emi Ushigome, Naoko Nakanishi, Mai Asano, Masahiro Yamazaki, Yuichiro Nishimoto, Takuji Yamada, Chizuru Fujikura, Takashi Asama, Nobuaki Okumura, Hiroshi Takakuwa, Ryoichi Sasano, Michiaki Fukui

“…Results Propolis improved the glucose tolerance (P < 0.001), increased the grip strength (P < 0.001) and the weight of soleus (P = 0.006) and plantaris muscles (P = 0.008). …”
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Using endogenous glycogen as relaxation agent for imaging liver metabolism by MRI by Shizhen Chen, Mou Jiang, Yaping Yuan, Baolong Wang, Yu Li, Lei Zhang, Zhong-Xing Jiang, Chaohui Ye, Xin Zhou

“…Glycogen plays essential roles in glucose metabolism. Imaging glycogen in the liver, the major glycogen reservoir in the body, may shed new light on many metabolic disorders. 13C magnetic resonance spectroscopy (MRS) has become the mainstream method for monitoring glycogen in the body. …”
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Predictive Value of Baseline FDG-PET/CT for the Durable Response to Immune Checkpoint Inhibition in NSCLC Patients Using the Morphological and Metabolic Features of Primary Tumors by Ken Kudura, Nando Ritz, Tim Kutzker, Martin H. K. Hoffmann, Arnoud J. Templeton, Robert Foerster, Michael C. Kreissl, Kwadwo Antwi

“…Objectives: We aimed to investigate the predictive value of baseline 2-deoxy-2-[¹⁸F]fluoro-D-glucose positron emission tomography/computed tomography (FDG-PET/CT) for durable responses to immune checkpoint inhibitors (ICIs) by linking the morphological and metabolic features of primary tumors (PTs) in nonsmall cell lung cancer (NSCLC) patients. …”
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Effects of Spinach Extract and Licorice Extract on Growth Performance, Antioxidant Capacity, and Gut Microbiota in Weaned Piglets by Jiahao Zhu, Jincong Lian, Haibin Deng, Junyi Luo, Ting Chen, Jiajie Sun, Yongliang Zhang, Yongan Yang, Pingxiang Liu, Qianyun Xi

“…Moreover, the MIX group exhibited a significant up-regulation of serum total protein, globulin, albumin, glucose, and triglyceride levels in comparison to the CON group (<i>p</i> < 0.05). …”
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Intensity Dependent Effects of Interval Resistance Training on Myokines and Cardiovascular Risk Factors in Males With Obesity by Ali Ataeinosrat, Ayoub Saeidi, Hossein Abednatanzi, Hiwa Rahmani, Asieh Abbassi Daloii, Zhaleh Pashaei, Vida Hojati, Gholam Basati, Ali Mossayebi, Ismail Laher, Michaela G. Alesi, Anthony C. Hackney, Trisha A. VanDusseldorp, Hassane Zouhal, Hassane Zouhal

“…Changes in fat mass, VO2peak, HDL, TG, glucose, activin A, decorin were not significant in LIIRT compared to the control group, while changes in activin A, follistatin, and TFG-β1 levels were greater in HIIRT and MIIRT groups compared to the LIIRT group (p&lt;0.05).ConclusionThe LIIRT, MIIRT, and HIIRT protocols all produced beneficial changes in decorin, activin A, follistatin, myostatin, and TGF-β1 levels, and cardiometabolic risk factors, with greater effects from the MIIRT and HIIRT protocols compared to LIIRT.…”
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Mitochondrial antioxidant SkQ1 decreases inflammation following hemorrhagic shock by protecting myocardial mitochondria by Bo Jia, Jingjing Ye, Lebin Gan, Rui Li, Mengwei Zhang, Diya Sun, Lin Weng, Yufei Xiong, Jun Xu, Peng Zhang, Wei Huang, Ming Zheng, Tianbing Wang

“…Mitochondria-targeted antioxidant SkQ1 attenuated the increased ROS induced by HS in myocardial tissues and by oxygen-glucose deprivation (OGD) in cardiomyocytes. Ultrastructurally, SkQ1 protected the myocardial mitochondrial structure and reduced the release of the peripheral blood mtDNA after HS. …”
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Diversity and biological activities of medicinal plants of Santiago island (Cabo Verde) by Maria M. Romeiras, Anyse P. Essoh, Sílvia Catarino, Joceline Silva, Katelene Lima, Eromise Varela, Mónica Moura, Isildo Gomes, Maria Cristina Duarte, Maria Paula Duarte

“…For α-glucosidase, the detected inhibitory activity (IC50 values from 2.0 ± 0.2 μg/mL to 9.9 ± 1.2 μg/mL) was significantly higher than that of acarbose, suggesting that extracts of both species can delay glucose absorption, thereby assisting in slowing down the progression of diabetes. …”
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Effects of different load weights on the work performance and physiological and hematobiochemical responses in working water buffalo by Visoky Paján-Jiménez, Fernando David Pazmiño-Rodríguez, Patricia Roldán-Santiago, Anna Dutro-Aceves, Luis Alberto de la Cruz-Cruz, Cristian Larrondo

“…However, 500 kg loads resulted in slower average speed (2.4 km, p = 0.0164), shorter working period (2.39 h, p < 0.0001) and distance traveled (7.29 km, p < 0.0001), and less total number of trips (8.27 trips, p < 0.0001) compared to 350 and 200 kg load weights (3.45 and 3.52 km/h, 2.55 and 2.79 h, 8.71 and 9.75 km, 10.94 and 16.61 trips, respectively); and the heaviest loads resulted in significantly higher (p < 0.005) respiratory rate, pulse, heart rate, rectal temperature, glucose, lactate dehydrogenase, creatine kinase, total protein, white blood cell count, neutrophils, lymphocytes, monocytes, eosinophils, and basophils. …”
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High folate receptor expression in gliomas can be detected in vivo using folate-based positron emission tomography with high tumor-to-brain uptake ratio divulging potential future... by Maxwell W. G. Miner, Heidi Liljenbäck, Heidi Liljenbäck, Jenni Virta, Salli Kärnä, Riikka Viitanen, Petri Elo, Maria Gardberg, Jarmo Teuho, Jarmo Teuho, Jarmo Teuho, Piritta Saipa, Johan Rajander, Hasan Mansour A Mansour, Nathan A. Cleveland, Philip S. Low, Xiang-Guo Li, Xiang-Guo Li, Xiang-Guo Li, Anne Roivainen, Anne Roivainen, Anne Roivainen, Anne Roivainen

“…Animals were divided into two groups, and were PET/CT imaged with either [18F]FOL or 2-deoxy-2-18F-fluoro-D-glucose ([18F]FDG) on 19 and 32-days post glioma grafting. …”
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Ultrasonic-Assisted Extraction, Structural Characteristics, and Antioxidant Activities of Polysaccharides from <i>Alpinia officinarum</i> Hance by Xuejing Jia, Guanghuo Liu, Yun Huang, Zipeng Li, Xiaofei Liu, Zhuo Wang, Rui Li, Bingbing Song, Saiyi Zhong

“…AOP30 had the lowest molecular weight of 11.07 kDa and mainly consisted of glucose (89.88%). The half inhibitory concentration (IC₅₀) value of AOP30 and AOP70 was lower than that of AOP50 in the ability to scavenge the ABTS radical, while a reverse trend was observed in reducing ferric ions. …”
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Novel Photosensitizer β-Mannose-Conjugated Chlorin e6 as a Potent Anticancer Agent for Human Glioblastoma U251 Cells by Yo Shinoda, Kohei Kujirai, Kohei Aoki, Mai Morita, Masato Masuda, Lihao Zhang, Zhou Kaixin, Akihiro Nomoto, Tsutomu Takahashi, Yayoi Tsuneoka, Jiro Akimoto, Hiromi Kataoka, Rioko Rachi, Atsushi Narumi, Tomokazu Yoshimura, Shigenobu Yano, Yasuyuki Fujiwara

“…The PDT effects of β-M-Ce6 were compared with those of talaporfin sodium (TS) and our previously reported photosensitizer β-glucose-conjugated chlorin e6 (β-G-Ce6). Cellular uptake of each photosensitizer and subcellular distribution were analyzed by fluorescence microscopy. β-M-Ce6 showed 1000× more potent PDT effects than those of TS, and these were similar to those of β-G-Ce6. β-M-Ce6 accumulation in U251 cells was much faster than TS accumulation and distributed to several organelles such as the Golgi apparatus, mitochondria, and lysosomes. …”
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Whole Body 3.0 T Magnetic Resonance Imaging in Lymphomas: Comparison of Different Sequence Combinations for Staging Hodgkin’s and Diffuse Large B Cell Lymphomas by Arash Latifoltojar, Mark K. J. Duncan, Maria Klusmann, Harbir Sidhu, Alan Bainbridge, Deena Neriman, Francesco Fraioli, Jonathan Lambert, Kirit M. Ardeshna, Shonit Punwani

“…To investigate the diagnostic value of different whole-body magnetic resonance imaging (WB-MRI) protocols for staging Hodgkin and diffuse-large B-cell lymphomas (HL and DLBCL), twenty-two patients (M/F 12/10, median age 32, range 22–87, HL/DLBCL 14/8) underwent baseline WB-MRI and ¹⁸F-2-fluoro-2-deoxy-D-glucose (¹⁸F-FDG) positron emission tomography (PET) fused with computed tomography (CT) scan ¹⁸F-FDG-PET-CT. …”
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A CASE OF DAPSONE-INDUCED HEMOLYTİC ANEMİA RELATED TO G6PD ENZYME DEFİCİENCY by Ali Dogan, Omer Ekıncı, Narin Yıldırım Dogan, Sinan Demırcıoglu, Cengiz Demır, Cihan Ural, Ramazan Esen

“…Here, we present a case diagnosed with pemphigus vulgaris who was determined to have Glucose-6-phosphate dehydrogenase (G6PD) deficiency based on the tests performed subsequent to hemolytic anemia that occurred during dapsone therapy. …”
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Fatty Liver as Potential Biomarker of Atherosclerotic Damage in Familial Combined Hyperlipidemia by Giuseppe Mandraffino, Carmela Morace, Maria Stella Franzè, Veronica Nassisi, Davide Sinicropi, Maria Cinquegrani, Carlo Saitta, Riccardo Scoglio, Sebastiano Marino, Alessandra Belvedere, Valentina Cairo, Alberto Lo Gullo, Michele Scuruchi, Giovanni Raimondo, Giovanni Squadrito

“…Lipid profile, fasting plasma glucose and insulin were determined by standard methods. …”
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