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51481
Development and Mechanistic Insight into the Enhanced Cytotoxic Potential of Parvifloron D Albumin Nanoparticles in EGFR-Overexpressing Pancreatic Cancer Cells
Published 2019-11-01“…Albumin nanoparticles (BSA NPs) were produced through a desolvation method. Glucose cross-linking and bioactive functionalization profiles of BSA platform were elucidated and analysed using static lattice atomistic simulations in vacuum. …”
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51482
Prospective Study Reveals Host Microbial Determinants of Clinical Response to Fecal Microbiota Transplant Therapy in Type 2 Diabetes Patients
Published 2022-03-01“…We observed a statistically significant decrease in HbA1c% (from 7.565 ± 0.148 to 7.190 ± 0.210, p<0.01), blood glucose (from 8.483 ± 0.497 to 7.286 ± 0.454 mmol/L, p<0.01), and uric acid (from 309.4 ± 21.5 to 259.1 ± 15.8 µmol/L, p<0.01) while a significant increase in postprandial C-peptide (from 4.503 ± 0.600 to 5.471 ± 0.728 ng/ml, p<0.01) at 12 weeks after FMT. …”
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51483
Co-Treatment of Purified Annatto Oil (<i>Bixa orellana</i> L.) and Its Granules (Chronic<sup>®</sup>) Improves the Blood Lipid Profile and Bone Protective Effects of Testosterone i...
Published 2021-08-01“…The following parameters were evaluated: food/water intake, weight, HDL, LDL, glucose, triglycerides (TG), total cholesterol (TC), alkaline phosphatase levels, blood phosphorus and calcium contents, femur weight, structure (through scanning electron microscopy), and calcium content (through atomic absorption spectrophotometry). …”
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51484
The effects of cool roofs on health, environmental, and economic outcomes in rural Africa: study protocol for a community-based cluster randomized controlled trial
Published 2024-01-01“…We are collecting outcome data on one primary endpoint - heart rate, (a measure of heat stress) and 22 secondary outcomes encompassing indoor climate parameters, blood pressure, body temperature, heat-related outcomes, blood glucose, sleep, cognition, mental health, health facility utilization, economic and productivity outcomes, mosquito count, life satisfaction, gender-based violence, and food consumption. …”
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51485
Nanomicellar Formulations Loaded with Histamine and Paclitaxel as a New Strategy to Improve Chemotherapy for Breast Cancer
Published 2023-02-01“…The aim of this work is to improve the therapeutic index of PTX through the design and characterization of novel nanomicellar polymeric formulations composed of a biocompatible copolymer Soluplus<sup>®</sup> (S), surface-decorated with glucose (GS), and co-loaded either with histamine (HA, 5 mg/mL) and/or PTX (4 mg/mL). …”
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51486
Association of outdoor artificial light at night with metabolic syndrome and the modifying effect of tree and grass cover
Published 2023-10-01“…MetS was defined by fasting blood glucose (FG), triglyceride (TG), high-density lipoprotein cholesterol (HDL-C), blood pressure (BP), and waist circumference (WC). …”
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51487
Intramuscular [<sup>18</sup>F]F-FDG Administration for Successful PET Imaging of Golden Hamsters in a Maximum Containment Laboratory Setting
Published 2022-11-01“…We propose the use of intramuscular (IM) administration of 2-deoxy-2[<sup>18</sup>F]fluoro-D-glucose ([<sup>18</sup>F]F-FDG) for PET imaging of hamsters in a biosafety level 4 (BSL-4) laboratory setting. …”
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51488
Empagliflozin is associated with lower cardiovascular risk compared with dipeptidyl peptidase-4 inhibitors in adults with and without cardiovascular disease: EMPagliflozin compaRat...
Published 2023-08-01“…Abstract Background Studies that have reported lower risk for cardiovascular outcomes in users of Sodium–Glucose Cotransporter-2 Inhibitors (SGLT-2i) are limited by residual cofounding and lack of information on prior cardiovascular disease (CVD). …”
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51489
Variety and quantity of dietary protein intake from different sources and risk of new-onset diabetes: a Nationwide Cohort Study in China
Published 2022-01-01“…New-onset diabetes was defined as self-reported physician-diagnosed diabetes or fasting glucose ≥7.0mmol/L or glycated hemoglobin ≥6.5% during the follow-up. …”
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51490
SIRT6 deficiency in endothelial cells exacerbates oxidative stress by enhancing HIF1α accumulation and H3K9 acetylation at the Ero1α promoter
Published 2023-08-01“…Methods The HUVECs model of oxygen–glucose deprivation/reperfusion (OGD/R) was established to simulate the endothelial IRI in vitro. …”
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51491
Effects of bisphenol A exposure at different circadian time on hepatic lipid metabolism in mice
Published 2022-12-01“…At ZT3 and ZT15, BPA did not alter body weight, plasma glucose, plasma total cholesterol, plasma low density lipoprotein cholesterol, and plasma triglycerides (P>0.05). …”
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51492
The Effects of Eight Weeks’ Very Low-Calorie Ketogenic Diet (VLCKD) on Liver Health in Subjects Affected by Overweight and Obesity
Published 2023-02-01“…Moreover, fasting blood glucose, insulin, triglycerides, total cholesterol, LDL-cholesterol, ALT, γGT, and FT3 blood concentrations, as well as insulin resistance (quantified by HOMAIR) and systolic and diastolic blood pressure levels, were significantly lower after VLCKD (<i>p</i> < 0.01 for all the parameters). …”
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51493
Relationship between sheep feces scores and gastrointestinal microorganisms and their effects on growth traits and blood indicators
Published 2024-02-01“…Significant differences were observed in Aspartate aminotransferase, Glucose, Total bilirubin, and Red Blood Cell Count between groups (p < 0.05). …”
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51494
Design, Synthesis, and Development of Pyrazolo[1,5-<i>a</i>]pyrimidine Derivatives as a Novel Series of Selective PI3K<i>δ</i> Inhibitors: Part II—Benzimidazole Derivatives
Published 2022-07-01“…Due to the high expression of these proteins in many human cells and their involvement in metabolism regulation, normal embryogenesis, or maintaining glucose homeostasis, the inhibition of PI3K (especially the first class which contains four subunits: <i>α</i>, <i>β</i>, <i>γ</i>, <i>δ</i>) is considered to be a promising therapeutic strategy for the treatment of inflammatory and autoimmune diseases such as systemic lupus erythematosus (SLE) or multiple sclerosis. …”
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51495
Pesquisa sobre escleroterapia líquida em varizes dos membros inferiores Survey on liquid sclerotherapy of lower limb varicose veins
Published 2013-03-01“…Gloves were worn during the procedure by 79.74% of the physicians; compression was employed by 52.59%; regarding physical activity after sclerotherapy , 46.12% of the physicians did not restrict, while 52.59% of them approved exercise after 1-3 days; ways to reduce pain during the procedure were used by 43.53% of the respondents; glucose 75% turned out to be the sclerosing agent most used by 35.34%; the most frequent systemic complication was lipothymia at 7.76%, and the most frequent local complication was hyperchromia at 66.38%; regarding sun exposure after the procedure: 28.02% released after the sclerotherapy with sunscreen, 24.57% after 15-30 days, and 25.43% after a period less than 15 days. …”
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51496
The <i>Opuntia</i> Effect Improves Dam-Kid Metabolic Markers, Augments Colostrum Quality and Enhances Kid-To-Dam Behavioral Interactions in Crossbred Goats and their Offspring unde...
Published 2020-05-01“…LW, BCS, and blood samples to quantify serum glucose (GLU) levels were collected weekly from day −25 up to day +15 in both dams (pre- and post-partum) and kids (post-partum). …”
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51497
Metabolite patterns associated with individual response to supervised exercise therapy in patients with intermittent claudication
Published 2022-01-01“…This alters energy expenditure in myoblasts by decreasing glucose uptake and may induce an acquired skeletal muscle myopathy. …”
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51498
Long-term green-Mediterranean diet may favor fasting morning cortisol stress hormone; the DIRECT-PLUS clinical trial
Published 2023-11-01“…Higher baseline FMC was directly associated with age, dysglycemia, MRI-assessed visceral adiposity, fasting plasma glucose (FPG), high-sensitivity C-reactive-protein (hsCRP), testosterone, Progesterone and TSH levels (p ≤ 0.05 for all). …”
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51499
基础胰岛素治疗2型糖尿病的有效性、安全性、初始最佳剂量和最佳维持剂量范围:一项meta分析的系统综述
Published 2023-05-01“…Abstract Aims To investigate the effectiveness, safety, optimal starting dose, optimal maintenance dose range, and target fasting plasma glucose of five basal insulins in insulin‐naïve patients with type 2 diabetes mellitus. …”
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51500
Biogenic Synthesis of Silver Nanoparticles Using <i>Catharanthus roseus</i> and Its Cytotoxicity Effect on Vero Cell Lines
Published 2022-09-01“…Moreover, five groups of rats including control and diabetic groups (NC1, PC2, DG1, DG2, and DG3) were investigated for their blood glucose and glycemic control analysis. Conclusions: The <i>C.…”
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