Reconstruction of a Genome-Scale Metabolic Network for Shewanella oneidensis MR-1 and Analysis of its Metabolic Potential for Bioelectrochemical Systems by Jiahao Luo, Jiahao Luo, Qianqian Yuan, Yufeng Mao, Fan Wei, Juntao Zhao, Wentong Yu, Wentong Yu, Shutian Kong, Yanmei Guo, Jingyi Cai, Xiaoping Liao, Zhiwen Wang, Hongwu Ma

“…The simulation of microbial fuel cells indicated that expanding the substrate spectrum of MR-1 to highly reduced feedstocks, such as glucose and glycerol, would be beneficial for electron generation. …”
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The sGC Activator Runcaciguat Has Kidney Protective Effects and Prevents a Decline of Kidney Function in ZSF1 Rats by Jan R. Kraehling, Agnes Benardeau, Tibor Schomber, Laura Popp, Julia Vienenkoetter, Heidrun Ellinger-Ziegelbauer, Mira Pavkovic, Elke Hartmann, Krystyna Siudak, Alexius Freyberger, Ina Hagelschuer, Ilka Mathar, Joerg Hueser, Michael G. Hahn, Volker Geiss, Frank Eitner, Peter Sandner

“…Additionally, average blood glucose levels measured as HbA1C, triglycerides, and cholesterol were increased by five times, twenty times, and four times, respectively, in obese ZSF1 compared to lean rats. …”
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Efficacy of Russian insulin biosimilars for type 1 diabetes in adolescents by V.V. Platonov, T.A. Dubinina, E.M. Patrakeeva, A.M. Rezvykh, N.V. Kazachenko

“…Blood sugar levels were measured by flash glucose monitoring (FGM). Time in the target range (TIR), time above the target range (TAR), time below the target range (TBR), and glycated hemoglobin (HbA1c) in the original insulin therapy and 3 and 6 months after switching to Russian biosimilars were evaluated. …”
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Short Duration Alagebrium Chloride Therapy Prediabetes Does Not Inhibit Progression to Autoimmune Diabetes in an Experimental Model by Danielle J. Borg, Pouya Faridi, Kai Lin Giam, Peta Reeves, Amelia K. Fotheringham, Domenica A. McCarthy, Sherman Leung, Micheal S. Ward, Brooke E. Harcourt, Rochelle Ayala, Jean L. Scheijen, David Briskey, Nadine L. Dudek, Casper G. Schalkwijk, Raymond Steptoe, Anthony W. Purcell, Josephine M. Forbes

“…ALT pre-treatment, prior to transfer of primed GC98 CD8⁺ T cell receptor transgenic T cells, reduced blood glucose concentrations and delayed diabetes, suggesting islet effects rather than immune modulation by ALT. …”
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Quantitative Research of 11C-CFT and 18F-FDG PET in Parkinson’s Disease: A Pilot Study With NeuroQ Software by Xun Sun, Xun Sun, Fang Liu, Fang Liu, Qingyao Liu, Qingyao Liu, Yongkang Gai, Yongkang Gai, Weiwei Ruan, Weiwei Ruan, Dilani Neranjana Wimalarathne, Dilani Neranjana Wimalarathne, Fan Hu, Fan Hu, Xubo Tan, Xubo Tan, Xiaoli Lan, Xiaoli Lan

“…Dopamine transporter (DAT) and glucose metabolism imaging have been applied in the diagnosis of Parkinson’s disease (PD). …”
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The brain protection of MLKL inhibitor necrosulfonamide against focal ischemia/reperfusion injury associating with blocking the nucleus and nuclear envelope translocation of MLKL a... by Xian-Yong Zhou, Bo Lin, Wei Chen, Rui-Qi Cao, Yi Guo, Ali Said, Taous Khan, Hui-Ling Zhang, Yong-Ming Zhu

“…In a transient middle cerebral artery occlusion (tMCAO) rat model in vivo, and an oxygen-glucose deprivation and reoxygenation (OGD/Re) injury model in both primary cultured astrocytes and human astrocytes, we show that necrosulfonamide (NSA), a MLKL specific inhibitor, reduces infarction volume and improves neurological deficits in tMCAO-treated rats. …”
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Cerebrovascular, Cognitive and Cardiac Benefits of SGLT2 Inhibitors Therapy in Patients with Atrial Fibrillation and Type 2 Diabetes Mellitus: Results from a Global Federated Healt... by Riccardo Proietti, José Miguel Rivera-Caravaca, Raquel López-Gálvez, Stephanie L. Harrison, Francisco Marín, Paula Underhill, Eduard Shantsila, Garry McDowell, Manlio Vinciguerra, Rhys Davies, Clarissa Giebel, Deirdre A. Lane, Gregory Y. H. Lip

“…Background: Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are effective anti-diabetic drugs improving cardiovascular outcomes in type 2 diabetes mellitus (T2DM) patients. …”
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Metabolic and functional substrates of impulsive decision-making in individuals with heroin addiction after prolonged methadone maintenance treatment by Qian Lv, Miao Zhang, Haifeng Jiang, Yilin Liu, Shaoling Zhao, Xiaomin Xu, Wenlei Zhang, Tianzhen Chen, Hang Su, Jiangtao Zhang, Heqiu Wang, Jianmin Zhang, Yuanjing Feng, Yongqiang Li, Biao Li, Min Zhao, Zheng Wang

“…We acquired functional magnetic resonance imaging (fMRI) data from 37 subjects with heroin addiction receiving long-term MMT and 33 healthy controls who performed a probabilistic reversal learning task, and measured their resting-state brain glucose using fluorine-18-fluorodeoxyglucose positron emission tomography (18F-FDG PET). …”
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Incidence and risk factors of gestational diabetes mellitus in Goba town, Southeast Ethiopia: a prospective cohort study by Vijay Kumar Chattu, Biniyam Sahiledengle, Yohannes Tekalegn, Demisu Zenbaba, Girma Beressa, Fikreab Desta, Daniel Atlaw, Tesfaye Assefa, Wogene Negash, Anwar Tahir, Tadele Regasa, Ayele Mamo, Zinash Teferu Enegeda, Damtew Solomon, Habtamu Gezahegn, Kebebe Bekele, Alelign Tasew, Fikadu Nugusu, Zerihun Shiferaw, Zegeye Feleke, Zegeye Regassa, Negesso Duguma

“…We aimed to assess the incidence of, and risk factors for, GDM in Goba town, Southeast Ethiopia.Design Prospective cohort study.Setting Goba town, Southeast Ethiopia.Participants Four hundred eighty pregnant women on antenatal care follow-up from 30 April to 30 September 2021.Primary and secondary outcomes Incidence and risk factors of GDM using fasting capillary blood glucose. Log-binomial model was used to identify the risk factors of GDM. …”
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Mechanism of Tripterygium wilfordii Hook.F.- Trichosanthes kirilowii Maxim decoction in treatment of diabetic kidney disease based on network pharmacology and molecular docking by Lingfei Lu, Lingfei Lu, Jinting Peng, Peijun Wan, Peijun Wan, Hongcheng Peng, Hongcheng Peng, Jiandong Lu, Jiandong Lu, Guoliang Xiong

“…Furthermore, the DKD model of human renal tubular cells (HK-2) induced by high glucose (HG) was selected, and the predicted results were verified by western blot analysis and immunofluorescence.Results: A total of 31 active components of LTD were screened out, and 196 targets were identified based on the TCMSP database. …”
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Association of Dietary Acid Load with the Prevalence of Metabolic Syndrome among Participants in Baseline Survey of the Japan Multi-Institutional Collaborative Cohort Study by Kokichi Arisawa, Sakurako Katsuura-Kamano, Hirokazu Uemura, Nguyen Van Tien, Asahi Hishida, Takashi Tamura, Yoko Kubo, Mineko Tsukamoto, Keitaro Tanaka, Megumi Hara, Toshiro Takezaki, Daisaku Nishimoto, Teruhide Koyama, Etsuko Ozaki, Sadao Suzuki, Takeshi Nishiyama, Kiyonori Kuriki, Aya Kadota, Naoyuki Takashima, Hiroaki Ikezaki, Masayuki Murata, Isao Oze, Keitaro Matsuo, Haruo Mikami, Yohko Nakamura, Kenji Takeuchi, Kenji Wakai

“…After adjusting for potential confounders, higher NEAP scores were associated with a significantly increased odds ratio (OR) of MetS, obesity, high blood pressure, and high fasting blood glucose. These associations remained significant after further adjustment for carbohydrate intake or two nutrient-pattern scores significantly associated with MetS. …”
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Nutrition and cataract in low-income Mexicans: experience in an Eye Camp by Claudia P Sánchez-Castillo, José Lara, José Romero-Keith, Guillermo Castorena, Antonio R Villa, Norma López, José Pedraza, Omar Medina, Carolina Rodríguez, Federico Chávez-Peón Medina, W.Philip T. James

“…The patients had high BMI values, with 32% of men and 30% of women overweight, and 2% and 14%, respectively, obese, with higher glucose, cholesterol and triglyceride values reflecting enhanced insulin resistance and lipid abnormalities. …”
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A Presurgical Unfavorable Prediction Scale of Endovascular Treatment for Acute Ischemic Stroke by Jingwei Li, Jingwei Li, Jingwei Li, Jingwei Li, Jingwei Li, Wencheng Zhu, Junshan Zhou, Wenwei Yun, Xiaobo Li, Qiaochu Guan, Weiping Lv, Yue Cheng, Huanyu Ni, Ziyi Xie, Mengyun Li, Lu Zhang, Yun Xu, Yun Xu, Yun Xu, Yun Xu, Yun Xu, Qingxiu Zhang, Qingxiu Zhang, Qingxiu Zhang, Qingxiu Zhang, Qingxiu Zhang

“…Furthermore, the top 5 variables suggesting unfavorable outcomes were namely admitting blood glucose levels, age, onset to EVT time, onset to hospital time, and National Institutes of Health Stroke Scale (NIHSS) scores (importance = 130.9, 102.6, 96.5, 89.5 and 84.4, respectively). …”
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From Bench to Bedside in Precision Medicine: Diabetes Mellitus and Peri-Implantitis Clinical Indices with a Short-Term Follow-Up: A Systematic Review and Meta-Analysis by Mario Dioguardi, Stefania Cantore, Salvatore Scacco, Cristian Quarta, Diego Sovereto, Francesca Spirito, Mario Alovisi, Giuseppe Troiano, Riccardo Aiuto, Daniele Garcovich, Vito Crincoli, Luigi Laino, Michele Covelli, Annarita Malcangi, Lorenzo Lo Muzio, Andrea Ballini, Michele Di Cosola

“…<i>Background and objective</i>: Diabetes mellitus (DM) refers to a group of metabolic disorders characterized by hyperglycemia resulting from impaired secretion or action of insulin. The high levels of glucose in the blood can negatively affect the healing processes through alterations in vascularization, bone remodeling, and with increased susceptibility to infections. …”
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3110 The association between components of the Life’s Simple Seven and incident end stage renal disease in the Southern Community Cohort Study by Mindy Pike, Cassianne Robinson-Cohen, Jennifer Morse, Thomas G. Stewart, William J. Blot, T. Alp Ikizler, Loren Lipworth

“…Modified definitions were used for consuming a healthy diet [Healthy Eating Index (HEI10) score>70] and for blood pressure, fasting plasma glucose, and total cholesterol, based on self-reported no history of diagnosis of hypertension, diabetes, and hypercholesterolemia, respectively. …”
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Serum/plasma biomarkers and the progression of cardiometabolic multimorbidity: a systematic review and meta-analysis by Yichen Jin, Yichen Jin, Ziyuan Xu, Ziyuan Xu, Yuting Zhang, Yuting Zhang, Yue Zhang, Yue Zhang, Danyang Wang, Danyang Wang, Yangyang Cheng, Yangyang Cheng, Yaguan Zhou, Yaguan Zhou, Muhammad Fawad, Muhammad Fawad, Xiaolin Xu, Xiaolin Xu, Xiaolin Xu

“…Lipid metabolism biomarkers were most reported to associate with CMM, including TC, TGs, HDL-C, LDL-C, and Lp(a). Fasting plasma glucose was also reported by several studies, and it was particularly associated with coexisting T2DM with vascular diseases. …”
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The association of apolipoprotein B with chronic kidney disease in the Chinese population by Yu Xu, Yu Xu, Yu Xu, Bo Liu, Lijin Lin, Lijin Lin, Fang Lei, Fang Lei, Tao Sun, Tao Sun, Xingyuan Zhang, Xingyuan Zhang, Xiaohui Song, Xiaohui Song, Xuewei Huang, Qiang Zeng, Jingjing Cai, Jingjing Cai, Zhifang Wang, Hongliang Li, Hongliang Li, Hongliang Li, Hongliang Li

“…Compared to the non-CKD group, the CKD group has higher levels of lipid profile and fasting glucose as well as the proportion of hypertension and hyperuricemia. …”
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Light-activated NIR-II imaging-guided tumor therapy with enhanced HPTT/starvation cycle by Gui-long Wu, Senyou Tan, Juan Wu, Feirong Wang, Xiaofeng Tan, Guodong Chen, Qinglai Yang

“…After the enhanced permeability and retention (EPR) effect causes IFT@PEG-GOX NPs to accumulate in tumors, glucose oxidase (GOx)-mediated tumor starvation may obstruct the production of adenosine triphosphate (ATP) and downregulation heat shock proteins (HSPs), thereby reducing the thermotolerance of cells. …”
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Adipokines Profile and Inflammation Biomarkers in Prepubertal Population with Obesity and Healthy Metabolic State by Lidia Cobos-Palacios, Mónica Muñoz-Úbeda, Cristina Gallardo-Escribano, María Isabel Ruiz-Moreno, Alberto Vilches-Pérez, Antonio Vargas-Candela, Isabel Leiva-Gea, Francisco J. Tinahones, Ricardo Gómez-Huelgas, María Rosa Bernal-López

“…Our aim was to evaluate the impact that lifestyle modifications, following a Mediterranean Diet (MedDiet) program and physical activity (PA) training, would have on inflammatory biomarkers in a metabolically healthy prepubertal population with obesity (MHOPp) from Malaga (Andalusia, Spain). (2) Methods: 144 MHOPp subjects (aged 5–9 years) were included in this study as they met ≤1 of the following criteria: waist circumference and blood pressure ≥ 90 percentile, triglycerides > 90 mg/dL, high-density lipoprotein cholesterol (HDL-c) < 40 mg/dL, or impaired fasting glucose (≥100 md/dL). Selected subjects followed a personalized intensive lifestyle modification. …”
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Dietary replacement of soybean meal with heat-treated soybean meal or high-protein corn distillers grains on nutrient digestibility and milk composition in mid-lactation cows by Rodrigo G. Chesini, Caio S. Takiya, Mauro S.S. Dias, Tássia B.P. Silva, Alanne T. Nunes, Nathalia T.S. Grigoletto, Guilherme G. da Silva, Paulo Cesar Vittorazzi, Jr., Luciana N. Rennó, Francisco P. Rennó

“…No differences were detected in milk fat yield and concentration, milk urea nitrogen, feed efficiency, or serum concentrations of urea and glucose. Overall, increasing dietary RUP by feeding HTSBM or FP improved intake of nutrients and milk yield without affecting feed efficiency. …”
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