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51561
4.6 Effects of Combined Therapy of Empagliflozin and Linagliptin Versus Metformin and Insulin Glargine on Blood Pressure and Vascular Function in Patients with Type 2 Diabetes
Published 2020-02-01“…Methods: In this study 101 patients with T2DM were randomized to receive either empagliflozin 10 mg and linagliptin 5 mg (E+L group) orally or metformin and insulin glargine (M+I group, with dose adjustments according to glucose levels), for 3 months. Patients underwent BP and vascular examination at baseline and after 12 weeks of treatment, including measurement of office and ambulatory BP and vascular function under clinical and ambulatory conditions by validated systems. …”
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51562
Mitochondria-associated membrane protein PACS2 maintains right cardiac function in hypobaric hypoxia
Published 2023-04-01“…Metabolomics analysis indicated suppression of glucose and fatty acids aerobic oxidation in HH conditions. …”
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51563
2,4‐Dihydroxybenzoic Acid, a Novel SA Derivative, Controls Plant Immunity via UGT95B17‐Mediated Glucosylation: A Case Study in Camellia Sinensis
Published 2024-02-01“…The exogenous application of 2,4‐DHBA and 2,5‐DHBA, as well as the accumulation of DHBA and plant resistance comparison, indicate that 2,4‐DHBA functions as a potentially bioactive molecule and is stored mainly as a glucose conjugate in tea plants, differs from the mechanism described in Arabidopsis. …”
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51564
Identification of Myocardial Insulin Resistance by Using Liver Tests: A Simple Approach for Clinical Practice
Published 2022-08-01“…In addition, we found that patients with mIR presented a reduced glucose uptake by the liver in comparison with patients with mIS. …”
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51565
Cardamom (<i>Elettaria cardamomum</i> (L.) Maton) Seeds Intake Increases Energy Expenditure and Reduces Fat Mass in Mice by Modulating Neural Circuits That Regulate Adipose Tissue...
Published 2023-02-01“…Accordingly, fasting and postprandial oxygen consumption, as well as fasting fat oxidation and postprandial glucose utilization were higher in mice fed with EC than in control. …”
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51566
Zootechnical Performance and Some Physiological Indices of Tambaqui, <i>Colossoma macropomum</i> Juveniles during Biofloc Maturation and in Different Feed Regimes
Published 2022-07-01“…FCR (1.90 ± 0.21), weight gain (9.81 ± 1.08 g), and SGR (1.26 ± 0.12%) were highest at 30 days of phase 1. The glucose level (118.23 ± 26.30 mg dL<sup>−</sup><sup>1</sup>) was highest on the 30th day. …”
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51567
Bone remodeling in experimental diabetes mellitus and surgical menopause in Wistar rats
Published 2023-11-01“…A weak negative correlation (r= -0.5, p<0,05) was found between glucose and osteocalcin levels (p=0.03). RANKL level was significantly lower in the «OE+DM» group (278,1 [273.1; 289.7] pg/mL) compared to the «OE» group (400.6 [394.5; 415.1] pg/mL), besides the OPG/RANKL ratio was higher in this group (0.03 [0.02; 0.035] and 0.01 [0.004; 0.014], respectively), p=0.05. …”
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51568
Sex-Dependent Role of Adipose Tissue HDAC9 in Diet-Induced Obesity and Metabolic Dysfunction
Published 2022-08-01“…Interestingly, female, but not male, adipocyte-specific <i>HDAC9</i> KO mice on HFD exhibited reduced body weight and visceral adipose tissue mass, adipocyte hypertrophy, and improved insulin sensitivity, glucose tolerance and adipogenic differentiation gene expression. …”
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51569
The Impact of LEP rs7799039 Polymorphism and Obesity on the Severity of Coronavirus Disease-19
Published 2023-02-01“…Also, obesity commonly provokes the severity of respiratory diseases so the correlation of LEP rs7799039 Polymorphism in corpulent patients with COVID-19 infection was clearly investigated in the current study.Methods: A total of 232 patients were recruited, 116 patients were obese with COVID-19 infection, and 116 patients were non obese COVID-19. Fasting blood glucose test (FBG), hemoglobin A1C (HbA1C), complete blood count (CBC), international normalized ratio (INR), urea, alanine transaminase (ALT), aspartate aminotransferase (AST), D dimer and C-reactive protein (CRP) were estimated. …”
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51570
Adiponectin preserves metabolic fitness during aging
Published 2021-04-01“…We directly assessed the effects of circulating adiponectin on the aging process and found that adiponectin null mice display exacerbated age-related glucose and lipid metabolism disorders. Moreover, adiponectin null mice have a significantly shortened lifespan on both chow and high-fat diet. …”
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51571
Ginsenoside Rd promotes omentin secretion in adipose through TBK1-AMPK to improve mitochondrial biogenesis via WNT5A/Ca2+ pathways in heart failure
Published 2023-04-01“…Consistently, exogenous omentin reduced mtROS levels and restored ΔψM to improve oxygen and glucose deprivation (OGD)-induced cardiomyocytes injury. …”
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51572
Exploring Synergistic Combinations in Extended and Pan-Drug Resistant (XDR and PDR) Whole Genome Sequenced <i>Acinetobacter baumannii</i>
Published 2023-05-01“…<b>Methods:</b> Non-replicate whole genome sequenced (illumina next-generation sequencing platform, Clevergene, India), <i>A. baumanii</i> (7 XDR, 1PDR) were subjected to in vitro synergy testing by checkerboard (CB) and time kill assay (TKA) after MIC determination, with glucose-6-phosphate being incorporated in all runs. …”
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51573
Fat mass and obesity-associated gene (FTO) hypermethylation induced by decabromodiphenyl ethane causing cardiac dysfunction via glucolipid metabolism disorder
Published 2022-06-01“…Furthermore, DBDPE could increase the serum levels of glucose and low-density lipoprotein but decrease the content of high-density lipoprotein. …”
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51574
Concurrent training and interindividual response in women with a high number of metabolic syndrome risk factors
Published 2022-09-01“…The main outcomes were waist circumference (WC), fasting plasma glucose (FPG), high-density lipids (HDL-c), triglycerides (Tg), and systolic (SBP) and diastolic (DBP) blood pressure, and secondary outcomes were body composition, anthropometric and physical fitness, determined before and after 20 weeks of concurrent training. …”
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51575
Inhibition of calpain9 attenuates peritoneal dialysis-related peritoneal fibrosis
Published 2022-12-01“…Next we inhibited Calpain activity or reduced Calpain9 expression, and then assessed changes in extracellular matrix and β-catenin.Results: Inhibition of calpain activity attenuated chlorhexidine glucose and peritoneal dialysis-induced peritoneal thickening and β-catenin expression in mice. …”
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51576
“How we do it”: A qualitative study of strategies for adopting an exercise routine while living with type 1 diabetes
Published 2023-01-01“…IntroductionFor people living with type 1 diabetes (T1D) the challenge of increasing daily physical activity (PA) is compounded by the increased risks of hypoglycemia and glucose variability. Little information exists on the lived experience of overcoming these barriers and adopting and maintaining an active lifestyle while living with T1D.Research Design and MethodsWe conducted a patient-led qualitative study consisting of semi-structured interviews or focus groups with 22 individuals at least 16 years old living with T1D. …”
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51577
Effect of arginine supplementation on the production of milk fat in dairy cows
Published 2022-10-01“…On the last day of each experimental period, blood was sampled to measure insulin, nitric oxide, glucose, and nonesterified fatty acid, and the liver and mammary gland were biopsied to measure the expression of genes. …”
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51578
Activated B cells suppress T-cell function through metabolic competition
Published 2022-12-01“…Moreover, activated B cells deprived T cells of glucose and produced lactic acid through their high glycolytic activity. …”
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51579
Efficacy and safety of one anastomosis gastric bypass versus Roux-en-Y gastric bypass for type 2 diabetes remission (ORDER): protocol of a multicentre, randomised controlled, open-...
Published 2022-09-01“…The primary endpoint is the complete diabetes remission rate defined as HbA1c≤6.0% and fasting plasma glucose≤5.6 mmol/L without any antidiabetic medications at 1 year after surgery. …”
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51580
CD300f immune receptor contributes to healthy aging by regulating inflammaging, metabolism, and cognitive decline
Published 2023-10-01“…This was associated with systemic inflammaging, increased cognitive decline, reduced brain glucose uptake observed by 18FDG PET scans, enrichment in microglial aging/neurodegeneration phenotypes, proteostasis alterations, senescence, increased frailty, and sex-dependent systemic metabolic changes. …”
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