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51701
Salvianolic acid A improve mitochondrial respiration and cardiac function via inhibiting apoptosis pathway through CRYAB in diabetic cardiomyopathy
Published 2023-04-01“…Treatment with SAA improved cardiac function, glucose, and lipid levels, mitochondrial respiration, and suppressed myocardial inflammation and apoptosis. …”
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51702
Calcium Biofortification of Rocha Pear Fruits: Implications on Mineral Elements, Sugars and Fatty Acids Accumulation in Tissues
Published 2022-09-01“…At harvest, the Ca treatments did not affect the levels of sucrose, glucose, fructose and sorbitol and, after storage, their concentrations remained higher in Ca-treated fruits. …”
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51703
Alterations of hepatic energy metabolism in murine models of obesity, diabetes and fatty liver diseasesResearch in context
Published 2023-08-01“…Mitochondrial respiration was measured by high-resolution respirometry and insulin-sensitive glucose metabolism by hyperinsulinemic-euglycemic clamps with stable isotope dilution. …”
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51704
Exploring the impact of short daily haemodialysis on muscle strength and bone health in end‐stage kidney disease patients
Published 2024-04-01“…SDH patients had lower levels of the uremic toxin asymmetric dimethyl‐l‐arginine (ADMA) (1.8 vs. 2.07 μM, P = 0.002) and fasting blood glucose (132.6 vs. 141.7 mg/dL, P < 0.02) than CHD group. …”
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51705
Community pharmacists’ perspectives on cardiovascular disease pharmaceutical care in the United Arab Emirates: a questionnaire survey-based analysis
Published 2023-09-01“…However, they showed low levels of involvement in other healthcare services, specifically in screening and measuring patients’ weight, glucose levels, and blood pressure, monitoring treatment responses, maintaining medical records, and reviewing medication refill histories. …”
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51706
Etiología de las infecciones urinarias adquiridas en la comunidad. Un estudio de 9 años
Published 2000-12-01“…Other microorganisms present were: Klebsiella pneumoniae (7,29%), Proteus mirabilis (6,33%), other Enterobacteriaceae (5,00%), Pseudomonas aeruginosa and other Gram-negative glucose non-fermenting rods (4,00%), Streptococcus Group B and others Streptococcus (2,00%), Enterococcus (2,00%), Staphylococcus aureus (1,00%), Aeromonas sp. (0,30%), Haemophilus influenzae (0,10%) and Candida sp. (1,00%). …”
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51707
Efficacy of empagliflozin in heart failure with preserved ejection fraction according to frailty status in EMPEROR‐Preserved
Published 2024-02-01“…The impact of frailty on HFpEF patients and any impact on the clinical benefits of sodium glucose co‐transporter 2 (SGLT2) inhibition in HFpEF have been described in only a limited number of trials. …”
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51708
P14 Criblage phytochimique, toxicité aiguë et évaluation de l'activité antidiabétique de l'écorce du tronc de Cylicodiscus gabunensis (Fabaceae)
Published 2023-12-01“…Une hyperglycémie significative a été observée 30 minutes après l’administration du D-glucose chez tous les animaux. Le témoin positif a présenté une baisse significative de la glycémie (70 mg/dL) dès la soixantième minute. …”
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51709
Inadequate diabetes knowledge is associated with poor glycemia control in patients with type 2 diabetes
Published 2023-05-01“…Main measurements: Glycated hemoglobin (HbA1c), glucose, and lipid profile levels were measured from fasting venous blood samples. …”
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51710
One-Year Changes in Urinary Microbial Phenolic Metabolites and the Risk of Type 2 Diabetes—A Case-Control Study
Published 2022-08-01“…However, when additionally adjusting for fasting plasma glucose, the statistical significance was lost. Changes in the dietary pattern can increase the concentrations of this compound, derived from many (poly)phenol-rich foods, and might be changing the gut microbial population as well, promoting the production of the metabolite.…”
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51711
The advanced lung cancer inflammation index is the optimal inflammatory biomarker of overall survival in patients with lung cancer
Published 2022-10-01“…However, the modified Glasgow prognostic score was superior to the other indicators in non‐small cell lung cancer patients (C‐index, 0.639) or patients aged ≥65 years (C‐index, 0.610), and the glucose‐to‐lymphocyte ratio performed better prognostic ability in patients with small cell lung cancer (C‐index, 0.601). …”
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51712
Effects of Cardiovascular Risk Factors on the Progression of Carotid Intima-media Thickening
Published 2023-05-01“…And 12 factors potentially associated with CIMT were identified by adaptive Lasso linear regression analysis, i.e., internal diameter of the common carotid artery, SBP, TC, physical activity level, ACR, smoking, alcohol consumption, CRP, LPA, ApoA/ApoB ratio, fasting plasma glucose, and family history of diabetes mellitus. …”
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51713
DJ-1 Proteoforms in Breast Cancer Cells: The Escape of Metabolic Epigenetic Misregulation
Published 2020-08-01“…In cancer cells, the high glycolytic flux induces carbonyl stress, a damaging condition in which the increase of reactive carbonyl species makes DNA, proteins, and lipids more susceptible to glycation. Together with glucose, methylglyoxal (MGO), a byproduct of glycolysis, is considered the main glycating agent. …”
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51714
Metabolomic‐based noninvasive serum test to diagnose nonalcoholic steatohepatitis: Results from discovery and validation cohorts
Published 2018-07-01“…When the analysis was performed excluding patients with glucose levels >136 mg/dL, the area under the receiver operating characteristic curve for the discrimination between NASH and NAFL increased to 0.81 ± 0.04 with sensitivity and specificity of 0.73 and 0.80, respectively. …”
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51715
Baseline Testosterone Predicts Body Composition and Metabolic Response to Testosterone Therapy
Published 2022-07-01“…Men with T ≥ 264 ng/dl showed significant decreases in HbA1c at 12 months (−3.1 ± 9.2 vs. 3.2 ± 13.9%; p = 0.005), fasting glucose at 18 months (−4.2 ± 31.9 vs. 13.0 ± 57.3%; p = 0.040), LDL at 6 months (−6.4 ± 27.5 vs. 12.8 ± 44.1%; p = 0.034), and leptin at 18 months (−40.2 ± 35.1 vs. −27.6 ± 31.0%; p = 0.034) compared to those with T < 264 ng/dl. …”
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51716
Treatment effect modification due to comorbidity: Individual participant data meta-analyses of 120 randomised controlled trials
Published 2023-06-01“…Although all were null, estimates of treatment effect modification were more precise in some cases (e.g., sodium-glucose co-transporter-2 (SGLT2) inhibitors for type 2 diabetes—interaction term for comorbidity count 0.004, 95% CI −0.01 to 0.02) while for others credible intervals were wide (e.g., corticosteroids for asthma—interaction term −0.22, 95% CI −1.07 to 0.54). …”
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51717
Biosynthetic pathway of prescription bergenin from Bergenia purpurascens and Ardisia japonica
Published 2024-01-01“…BpOMT1 and AjOMT1 facilitate the methylation reaction at the 4-OH position of GA, resulting in the formation of 4-O-methyl gallic acid (4-O-Me-GA). AjCGT1 transfers a glucose moiety to C-2 to generate 2-Glucosyl-4-O-methyl gallic acid (2-Glucosyl-4-O-Me-GA). …”
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51718
Phthalate exposure and childhood overweight and obesity: Urinary metabolomic evidence
Published 2018-12-01“…Meanwhile, increased MnBP concentration was also significantly correlated with decreased levels of lactate, glucose 6-phosphate, d-fructose 6-phosphate, palmitic acid, 4-acetamidobutyric acid, l-glutamic acid, n-acetyl-l-phenylalanine, iminodiacetic acid, hydroxyproline, pipecolinic acid, l-ornithine, n-acetyl-l-glutamic acid, guanosine, cytosin, and (s)-mandelic acid in the normal weight subjects. …”
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51719
Hypoglycemic Activity of Aqueous Extract of Latex from <i>Hancornia speciosa</i> Gomes: A Study in Zebrafish and In Silico
Published 2021-08-01“…We then tested treatments with LxHs (500, 1000, and 1500 mg/kg) by assessing blood glucose levels in alloxan-induced diabetic animals, and metformin was used as a control. …”
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51720
E96V Mutation in the <i>Kdelr3</i> Gene Is Associated with Type 2 Diabetes Susceptibility in Obese NZO Mice
Published 2023-01-01“…A linkage study performed in this population led to the identification of the novel T2D-associated quantitative trait locus (QTL) <i>Nbg15</i> (NZO blood glucose on chromosome 15, Logarithm of odds (LOD) 6.6). …”
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