Emagrecimento e desempenho cardíaco Weight loss and cardiac performance by Antonio Carlos Valezi, Vitor Hugo Soares Machado

“…The weight loss determine blood pressure decrease and improvement in parameters of lipid and glucose levels. Weight loss and maintenance reduce the risk factors for cardiovascular disease, making reversible cardiac changes resulting from obesity. …”
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Cyclo-(Phe-Tyr) as a novel cyclic dipeptide compound alleviates ischemic/reperfusion brain injury via JUNB/JNK/NF-κB and SOX5/PI3K/AKT pathways by Jiale Cai, Jiayin Liang, Yutong Zhang, Lin Shen, Huiting Lin, Tao Hu, Sikai Zhan, Meixia Xie, Shengwang Liang, Minghua Xian, Shumei Wang

“…To investigate the mechanism, we established an in vitro BV2 cell oxygen-glucose deprivation/reperfusion (OGD/R) model and used siRNA as well as an inhibitor. …”
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Hypothalamic Pomc expression restricted to GABAergic neurons suppresses Npy overexpression and restores food intake in obese mice by Milagros Trotta, Estefanía Pilar Bello, Ramiro Alsina, María Belén Tavella, José Luis Ferrán, Marcelo Rubinstein, Viviana Florencia Bumaschny

“…Objective: Hypothalamic arcuate proopiomelanocortin (Arc-POMC) neurons are involved in different physiological processes such as the regulation of energy balance, glucose homeostasis, and stress-induced analgesia. …”
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Effect of Antiepileptic Drugs on Serum Lipid Profile among Children with Epilepsy at a Tertiary Care Hospital, Chennai, India by Pon Divya, R Suresh Kumar, Velmurugan Lakshmi, Sivasambo Kalpana

“…A blood sample (3 mL) was drawn after an overnight fast for serum glucose, liver enzymes, Total Cholesterol (TC), High Density Lipoprotein-Cholesterol (HDL-C), Low Density Lipoprotein-Cholesterol (LDL-C), Very Low Density Lipoprotein-Cholesterol (VLDL-C) and Triglycerides (TG) measurement. …”
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Effect of Codonopsis Radix and Polygonati Rhizoma on the regulation of the IRS1/PI3K/AKT signaling pathway in type 2 diabetic mice by Yong-po Mao, Yong-po Mao, Yi-ming Song, Sheng-wang Pan, Ning Li, Ning Li, Ning Li, Wen-xiang Wang, Wen-xiang Wang, Wen-xiang Wang, Bin-bin Feng, Bin-bin Feng, Bin-bin Feng, Jian-hai Zhang, Jian-hai Zhang, Jian-hai Zhang

“…Body weight and fasting blood glucose (FBG) were measured on a weekly basis. Enzyme-linked immunosorbent assay (ELISAs) were used to evaluate the serum and liver samples. …”
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Peripheral modulation of antidepressant targets MAO-B and GABAAR by harmol induces mitohormesis and delays aging in preclinical models by Luis Filipe Costa-Machado, Esther Garcia-Dominguez, Rebecca L. McIntyre, Jose Luis Lopez-Aceituno, Álvaro Ballesteros-Gonzalez, Andrea Tapia-Gonzalez, David Fabregat-Safont, Tobias Eisenberg, Jesús Gomez, Adrian Plaza, Aranzazu Sierra-Ramirez, Manuel Perez, David Villanueva-Bermejo, Tiziana Fornari, María Isabel Loza, Gonzalo Herradon, Sebastian J. Hofer, Christoph Magnes, Frank Madeo, Janet S. Duerr, Oscar J. Pozo, Maximo-Ibo Galindo, Isabel del Pino, Riekelt H. Houtkooper, Diego Megias, Jose Viña, Mari Carmen Gomez-Cabrera, Pablo J. Fernandez-Marcos

“…Diet-induced pre-diabetic male mice improve their glucose tolerance, liver steatosis and insulin sensitivity after treatment with harmol. …”
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急性冠状动脉综合征患者应激性高血糖率与长期预后:一项多中心全国性研究 by Guyu Zeng, Ying Song, Zheng Zhang, Jingjing Xu, Zhenyu Liu, Xiaofang Tang, XiaoZeng Wang, Yan Chen, Yongzhen Zhang, Pei Zhu, Xiaogang Guo, Lin Jiang, Zhifang Wang, Ru Liu, Qingsheng Wang, Yi Yao, Yingqing Feng, Yaling Han, Jinqing Yuan

“…SHR was calculated by the following formula: SHR = admission glucose (mmol/L)/(1.59 × HbA1c [%]−2.59). The primary end point was a major adverse cardiovascular event (MACE) during follow‐up, a composite of all‐cause death, myocardial infarction, and unplanned revascularization. …”
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Cross Talk between Adipose Tissue and Placenta in Obese and Gestational Diabetes Mellitus Pregnancies via Exosomes by Nanthini Jayabalan, Soumyalekshmi Nair, Zarin Nuzhat, Gregory E. Rice, Gregory E. Rice, Felipe A. Zuñiga, Luis Sobrevia, Luis Sobrevia, Luis Sobrevia, Andrea Leiva, Carlos Sanhueza, Jaime Agustín Gutiérrez, Jaime Agustín Gutiérrez, Martha Lappas, Martha Lappas, Dilys Jane Freeman, Carlos Salomon, Carlos Salomon, Carlos Salomon, Carlos Salomon

“…The adipose tissue is an endocrine organ, secreting various adipokines, enzymes, growth factors, and hormones that take part in glucose and lipid metabolism. In obesity, the greater portion of the adipose tissue comprises fat, and there is increased pro-inflammatory cytokine secretion, macrophage infiltration, and reduced insulin sensitivity. …”
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Empagliflozin Attenuates Non-Alcoholic Fatty Liver Disease (NAFLD) in High Fat Diet Fed ApoE^(-/-) Mice by Activating Autophagy and Reducing ER Stress and Apoptosis by Narjes Nasiri-Ansari, Chrysa Nikolopoulou, Katerina Papoutsi, Ioannis Kyrou, Christos S. Mantzoros, Georgios Kyriakopoulos, Antonios Chatzigeorgiou, Vassiliki Kalotychou, Manpal S. Randeva, Kamaljit Chatha, Konstantinos Kontzoglou, Gregory Kaltsas, Athanasios G. Papavassiliou, Harpal S. Randeva, Eva Kassi

“…Results: Empagliflozin-treated mice exhibited reduced fasting glucose, total cholesterol and triglyceride serum levels, as well as decreased NAFLD activity score, decreased expression of lipogenic enzymes (<i>Fasn</i>, <i>Screbp-1c</i> and <i>Pck-1</i>) and inflammatory molecules (<i>Mcp-1</i> and <i>F4/80</i>), compared to the Control group. …”
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Perfil de prescripción de nutrición parenteral en recién nacidos de muy bajo peso al nacer: período 2006 a 2010 Profile of parenteral nutrition prescription in very low birth weigh... by P. Gomis Muñoz, G. Bustos Lozano, J. Becerril Morancos, C. M. Fernández-Llamazares, C. R. Pallás Alonso

“…Materials and methods: Amino acids, glucose, lipids (g/ kg/day) and calories (kcal/kg/day) prescribed in the PN of the first week of life were collected. …”
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SIRT1-dependent deacetylation of Txnip H3K9ac is critical for exenatide-improved diabetic kidney disease by Mei-jun Wang, Xiang Cai, Ri-ying Liang, En-ming Zhang, Xiao-qi Liang, Hua Liang, Chang Fu, An-dong Zhou, Yi Shi, Fen Xu, Meng-yin Cai

“…The downregulation of Txnip expression by exendin-4 in high-glucose-treated SV40 MES13 cells was hampered during Sirt1 knockdown. …”
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Connectedness between Intensive and Extensive Ruminant Production Systems: Using Dairy Cow Feed Leftovers to Generate Out-of-Season Bio-Economic Indices in Goats by Cesar A. Meza-Herrera, Maria G. Machado-Ramos, Angeles De Santiago-Miramontes, Miguel Mellado, Cayetano Navarrete-Molina, Maria de los Ángeles Sariñana-Navarrete, José R. Arévalo, Oscar Angel-García, Alan S. Alvarado-Espino, Rafael Rodriguez-Venegas

“…The last result occurred despite no differences (<i>p</i> > 0.05) regarding BW, BCS, and serum glucose concentrations between experimental groups. …”
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Effects of different n-6/n-3 polyunsaturated fatty acids ratios on lipid metabolism in patients with hyperlipidemia: a randomized controlled clinical trial by Yiwei Yang, Yiwei Yang, Yiwei Yang, Yanping Xia, Yanping Xia, Yanping Xia, Baixi Zhang, Dan Li, Dan Li, Dan Li, Jiai Yan, Jiai Yan, Jiai Yan, Ju Yang, Ju Yang, Ju Yang, Jing Sun, Jing Sun, Jing Sun, Hong Cao, Hong Cao, Hong Cao, Yingyu Wang, Yingyu Wang, Yingyu Wang, Feng Zhang, Feng Zhang, Feng Zhang, Feng Zhang

“…Anthropometric, lipid and blood glucose parameters and quality of life were assessed at baseline and 60 days after intervention.ResultAfter 60 days, high-density lipoprotein cholesterol (HDL-c) level was increased (p = 0.029) and Total cholesterol (TC) level was decreased (p = 0.003) in the MP group. …”
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The hemoglobin glycation index predicts the risk of adverse cardiovascular events in coronary heart disease patients with type 2 diabetes mellitus by Shuai Xu, Shuai Xu, Shuai Xu, Zhen Qin, Zhen Qin, Zhen Qin, Ruixia Yuan, Xiaolin Cui, Xiaolin Cui, Li Zhang, Li Zhang, Li Zhang, Jing Bai, Jing Bai, Jing Bai, Gangqiong Liu, Gangqiong Liu, Gangqiong Liu, Zeyu Wang, Zeyu Wang, Zeyu Wang, Fengyi Yu, Fengyi Yu, Fengyi Yu, Yan Lv, Yan Lv, Yan Lv, Jinying Zhang, Jinying Zhang, Jinying Zhang, Junnan Tang, Junnan Tang, Junnan Tang

“…Data including fasting blood glucose (FPG/FBG) and glycated hemoglobin A1c (HbA1c) were collected. …”
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Effects of dietary supplementation of natural Spirulina on growth performance, hemato-biochemical indices, gut health, and disease resistance to Aeromonas hydrophila of Stinging ca... by Mobasshsirin Rahman, Md. Abdullah Al Mamun, Sanjay Singh Rathore, Shishir Kumar Nandi, Zulhisyam Abdul Kari, Lee Seong Wei, Albaris B. Tahiluddin, Md. Moshiur Rahman, Nesara Kadadakatte Manjappa, Arman Hossain, Shamima Nasren, M.M. Mahbub Alam, Walter G. Bottje, Guillermo Téllez-Isaías, Muhammad Anamul Kabir

“…The basal diet-fed fish had lower (p < 0.05) total protein, globulin, and albumin levels and higher glucose, cholesterol, and triglyceride levels than those fed with other test diets. …”
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Role of Dietary Inclusion of Phytobiotics and Mineral Adsorbent Combination on Dairy Cows′ Milk Production, Nutrient Digestibility, Nitrogen Utilization, and Biochemical Parameters... by Nikolai P. Buryakov, Larisa V. Sycheva, Vladimir I. Trukhachev, Anastasiya S. Zaikina, Maria A. Buryakova, Ilia N. Nikonov, Alexander S. Petrov, Andrey V. Kravchenko, Mohamed M. Fathala, Ivan K. Medvedev, Dmitrii E. Aleshin

“…There was an increase (<i>p</i> < 0.05) in the concentration of rumen ammonia in the control group compared to the other groups. The glucose content of those cows that received FG and TMS + FG combination increased (<i>p</i> < 0.05) by 0.76 mmol/L and 0.90 mmol/l in relation to the control group. …”
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A multi-center study on the association between serum magnesium levels and allostatic load in hemodialysis patients by Yingxin Zhang, Zhengling Yang, Huan Yang, Xiuyong Li, Zhi Liu, Youwei Bai, Guangrong Qian, Han Wu, Ji Li, Yuwen Guo, Shanfei Yang, Lei Chen, Jian Yang, Jiuhuai Han, Shengyin Ma, Jing Yang, Linfei Yu, Runzhi Shui, Xiping Jin, Hongyu Wang, Fan Zhang, Tianhao Chen, Xinke Li, Xiaoying Zong, Li Liu, Jihui Fan, Wei Wang, Yong Zhang, Guangcai Shi, Deguang Wang, Shuman Tao

“…Serum Mg2+ was negatively correlated with body mass index, fasting blood glucose (Glu), and C-reactive protein and positively correlated with high-density lipoprotein, low-density lipoprotein, total cholesterol, diastolic blood pressure (DBP), and serum phosphorus. …”
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Increased adipose tissue lipolysis in dairy cows with fatty liver is associated with enhanced autophagy activity by Jihong Dong, Kaiming Yue, Juan J. Loor, Ahmad Aboragah, Guojin Li, Linfang Chen, Yuxiang Song, Xiliang Du, Guowen Liu, Zhe Wang, Xiaobing Li, Xinwei Li

“…Serum concentrations of free fatty acids and β-hydroxybutyrate were greater and glucose concentration was lower in cows with fatty liver, which we determined by using commercially-available kits. …”
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Activity tracker-based metrics as digital markers of cardiometabolic health in working adults : cross-sectional study by Rykov, Yuri, Thach, Thuan-Quoc, Dunleavy, Gerard, Roberts, Adam Charles, Christopoulos, George I., Soh, Chee-Kiong, Car, Josip

“…The following clinical biomarkers were collected: BMI, waist circumference, waist-to-hip ratio, blood pressure, triglycerides (TGs), high-density lipoprotein (HDL) and low-density lipoprotein cholesterol, and blood glucose. We used a range of wearable-derived metrics based on steps, heart rate (HR), and energy expenditure, including measures of stability of circadian activity rhythms, sedentary time, and time spent at various intensities of physical activity. …”
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Quantitative microvascular analysis with wide-field optical coherence tomography angiography in eyes with diabetic retinopathy by Tan, Bingyao, Chua, Jacqueline, Lin, Emily, Cheng, Joyce, Gan, Alfred, Yao, Xinwen, Wong, Damon W. K., Sabanayagam, Charumathi, Wong, Doric, Chan, Choi Mun, Wong, Tien Yin, Schmetterer, Leopold, Tan, Gavin S.

“…Case patients were those with type 2 diabetes for more than 5 years and bilateral DR diagnosed by fundus imaging; control participants included those with no self-reported history of diabetes, a fasting glucose level within the normal range in the past year, and no ocular pathologic findings. …”
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