-
51881
Metabolic syndrome and level of lipopolysaccharide binding protein: proportionate, associated factors and the effectiveness study of probiotics supplementation among population...
Published 2022“…Anthropometric measurements, body composition analysis (BCA), and biochemical assays (fasting glucose, lipid profile, insulin, hs-CRP, IL-6, TNF-, and LBP) were performed. …”
Get full text
Thesis -
51882
Enzymatic conversion strategies of starch to maltooligosaccharides by maltogenic amylase and cyclodextrin glucanotransferase
Published 2020“…This is followed by hydrolysis of CDs by intracellular maltogenic amylase (MAG1) into glucose, maltose and maltooligosaccharides (MOS). …”
Get full text
Thesis -
51883
毛柳苷在脑缺血再灌注后抑制神经元自噬及神经保护作用研究 Neuroprotective Effect and Mechanism of Salidroside in Cerebral Ischemia-reperfusion Injury in Mouse Model...
Published 2022-09-01“…原代大鼠神经元培养10 d后进行氧糖剥夺(oxygen glucose deprivation,OGD),将细胞分为以下6组:对照(control,CON)组、OGD 1 h后复氧1 h(OGD 1 h)组、OGD 1 h后复氧4 h(OGD 4 h)组、SAL组、OGD 1 h后复氧1 h/全程SAL治疗(OGD+SAL 1 h)组、OGD 1 h后复氧4 h/全程SAL治疗(OGD+SAL 4 h)组,CON组和SAL组不进行OGD,SAL剂量50 μmol/L。…”
Get full text
Article -
51884
Effects of diurnal temperature fluctuations on growth performance, energy metabolism, stress response, and gut microbes of juvenile mud crab Scylla paramamosain
Published 2022-11-01“…The crab in SF and MF had a shorter, but LF had a longer molt interval compared with the crab in the CT group. Cortisol, blood glucose (GLU), total cholesterol (T-CHO) and triglyceride (TG) levels peaked in the LF group. …”
Get full text
Article -
51885
PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion
Published 2023-05-01“…PSGL-1 deficiency empowers CD8+ T cells to respond to low-affinity TCR ligands and inhibit growth of PD-1-blockade-resistant melanoma by enabling tumor-infiltrating T cells to sustain an elevated metabolic gene signature supportive of increased glycolysis and glucose uptake to promote effector function. This outcome is coupled to an increased abundance of CD8+ T cell stem cell-like progenitors that maintain effector functions. …”
Get full text
Article -
51886
Efficacy and safety of umbilical cord-derived mesenchymal stem cells in Chinese adults with type 2 diabetes: a single-center, double-blinded, randomized, placebo-controlled phase I...
Published 2022-05-01“…The levels of HbA1c decreased 1.31% (9.02 ± 1.27% to 7.52 ± 1.07%, p < 0.01) in the UC-MSCs group, and only 0.63% in the placebo group (8.89 ± 1.11% to 8.19 ± 1.02%, p˃0.05; p = 0.0081 between both groups). The glucose infusion rate (GIR) increased significantly in the UC-MSCs group (from 3.12 to 4.76 mg/min/kg, p < 0.01), whereas no significant change was observed in the placebo group (from 3.26 to 3.60 mg/min/kg, p ˃ 0.05; p < 0.01 between both groups). …”
Get full text
Article -
51887
National Essential Public Health Services Programs over the Past Decade Research Report Two:Progress and Achievements of the Implementation of National Essential Public Health Serv...
Published 2022-09-01“…The blood pressure / blood glucose control rate in the population managed for hypertension / diabetes has increased by 16.84% and 24.69% respectively in the past decade, with an average annual growth rate of 3.28% and 5.56% respectively. …”
Get full text
Article -
51888
Methylprednisolone therapy induces differential metabolic trajectories in severe COVID-19 patients
Published 2023-12-01“…The metabolic pathways differing between the two groups over time included galactose metabolism, glucose and gluconeogenesis, N-glycan metabolism, and prostaglandin formation from arachidonate. …”
Get full text
Article -
51889
Influencia del volumen peritoneal residual en los resultados de la prueba de equilibrio peritoneal. Estudio prospectivo
Published 2023-03-01“…Method: Following a prospective design, we calculated Vrpre and Vrpost in 116 patients, incident or prevalent on DP, who underwent one or two (n = 27) PET with 3.86/4.25% glucose-based PD solutions and complete drainage at 60 min. …”
Get full text
Article -
51890
Outdoor artificial light at night exposure and gestational diabetes mellitus: a case–control study
Published 2024-04-01“…GDM was diagnosed through oral glucose tolerance tests. Conditional logistic regression models were used to evaluate the association between ALAN exposure and GDM risk. …”
Get full text
Article -
51891
Activation of Systemic Inflammation and Oxidative Stress in Adolescent Girls with Polycystic Ovary Syndrome in Combination with Metabolic Disorders and Excessive Body Weight
Published 2020-05-01“…Patients with PCOS were divided into groups according to the presence of metabolic disorders (MD) (impaired glucose tolerance and/or over insulin resistance) and normal weight or excessive weight (NW or OW). …”
Get full text
Article -
51892
Role of nerve signal transduction and neuroimmune crosstalk in mediating the analgesic effects of acupuncture for neuropathic pain
Published 2023-01-01“…Acupuncture also inhibits neuronal glucose metabolism by downregulating mPFC's GLUT-3 and promotes metabolic alterations of the brain, thus exerting an analgesic effect. …”
Get full text
Article -
51893
Trehalose Attenuates Oxidative Stress and Endoplasmic Reticulum Stress-Mediated Apoptosis in IPEC-J2 Cells Subjected to Heat Stress
Published 2022-08-01“…The HS-induced ERS response was evidenced by the increased protein expressions of glucose-regulated protein 78 (GRP78) (<i>p</i> < 0.01), eukaryotic translation initiation factor 2α (p-eif2α) (<i>p</i> < 0.01), transcription activator 4 (ATF4) (<i>p</i> < 0.01), and the protein expression of C/EBP homologous protein (CHOP) (<i>p</i> < 0.01), which were the four hallmarks of ERS. …”
Get full text
Article -
51894
Efficacy and safety of anti-androgens in the management of polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trialsResearch in context
Published 2023-09-01“…In meta-analysis, anti-androgens + lifestyle were superior to metformin + lifestyle for hirsutism (weighted mean difference [WMD] [95% CI]: −1.59 [−3.06, −0.12], p = 0.03; I2 = 74%), SHBG (7.70 nmol/l [0.75, 14.66], p = 0.03; I2 = 0%), fasting insulin and fasting insulin: glucose ratio (−2.11 μU/ml [−3.97, −0.26], p = 0.03; I2 = 0% and −1.12 [−1.44, −0.79], p < 0.0001, I2 = 0%, respectively), but were not superior to placebo + lifestyle for hirsutism (−0.93, [−3.37, 1.51], p = 0.45; I2 = 76%) or SHBG (9.72 nmol/l [−0.71, 20.14], p = 0.07; I2 = 31%). …”
Get full text
Article -
51895
Oral 24-week probiotics supplementation did not decrease cardiovascular risk markers in patients with biopsy proven NASH: A double-blind placebo-controlled randomized study
Published 2023-01-01“…Treatment did not promote any clinically significant changes in body mass index or laboratory, including lipid and glucose profile. High CVR patients through atherogenic indexes decreased from baseline in both groups, as well as PAI-1 and miR-122 levels, although there was no difference between probiotics and placebo. …”
Get full text
Article -
51896
Remission of type 2 diabetes and improved diastolic function by combining structured exercise with meal replacement and food reintroduction among young adults: the RESET for REMISS...
Published 2022-09-01“…The primary outcome is T2DM remission, (haemoglobin A1c of less than 6.5% at 24 weeks, without use of glucose-lowering medications during maintenance). …”
Get full text
Article -
51897
Association between breast nodules, anxiety, depression and metabolic risk factors in a Chinese cohort
Published 2023-05-01“…Serum samples were used to measure fasting blood glucose, uric acid, triglycerides, total cholesterol, urea nitrogen, alanine transaminase, aspartate transaminase, albumin, high-density lipoprotein, low-density lipoprotein. …”
Get full text
Article -
51898
Predicting depressive symptom by cardiometabolic indicators in mid-aged and older adults in China: a population-based cross-sectional study
Published 2023-06-01“…The study evaluated the relationship between cardiometabolic indicators and depression by measuring 13 indicators, including body mass index (BMI), waist circumference, waist-height ratio (WHtR), conicity index, visceral adiposity index (VAI), Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), a body shape index (ABSI), body roundness index (BRI), triglyceride glucose index (TyG-index) and its correlation index (TyG-BMI, TyG-waist circumference, TyG-WHtR). …”
Get full text
Article -
51899
The association between stress hyperglycemia and unfavorable outcomes in patients with anterior circulation stroke after mechanical thrombectomy
Published 2023-01-01“…The stress hyperglycemia ratio (SHR) was calculated as fasting plasma glucose (mmol/L) divided by glycosylated hemoglobin (%). …”
Get full text
Article -
51900
Muscle wasting in patients with end‐stage renal disease or early‐stage lung cancer: common mechanisms at work
Published 2019-04-01“…Functional analysis revealed up to 238 proteins belonging to nine metabolic processes (inflammatory response, proteolysis, cytoskeleton organization, glucose metabolism, muscle contraction, oxidant detoxification, energy metabolism, fatty acid metabolism, and extracellular matrix) involved in and/or altered by the atrophying programme in both LC and HD patients. …”
Get full text
Article