Metabolic syndrome and level of lipopolysaccharide binding protein: proportionate, associated factors and the effectiveness study of probiotics supplementation among population... by Harfeel, Sondos Abd-Erraheem Jameel

“…Anthropometric measurements, body composition analysis (BCA), and biochemical assays (fasting glucose, lipid profile, insulin, hs-CRP, IL-6, TNF-, and LBP) were performed. …”
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Enzymatic conversion strategies of starch to maltooligosaccharides by maltogenic amylase and cyclodextrin glucanotransferase by Ahmad, Rabi’atul Adawiyah

“…This is followed by hydrolysis of CDs by intracellular maltogenic amylase (MAG1) into glucose, maltose and maltooligosaccharides (MOS). …”
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毛柳苷在脑缺血再灌注后抑制神经元自噬及神经保护作用研究 Neuroprotective Effect and Mechanism of Salidroside in Cerebral Ischemia-reperfusion Injury in Mouse Model... by 温少红，刘宽，赵顺英，董雯，陈青芳，陈文涛，叶维贞，姜鸣钰，刘向荣

“…原代大鼠神经元培养10 d后进行氧糖剥夺（oxygen glucose deprivation，OGD），将细胞分为以下6组：对照（control，CON）组、OGD 1 h后复氧1 h（OGD 1 h）组、OGD 1 h后复氧4 h（OGD 4 h）组、SAL组、OGD 1 h后复氧1 h/全程SAL治疗（OGD+SAL 1 h）组、OGD 1 h后复氧4 h/全程SAL治疗（OGD+SAL 4 h）组，CON组和SAL组不进行OGD，SAL剂量50 μmol/L。…”
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Effects of diurnal temperature fluctuations on growth performance, energy metabolism, stress response, and gut microbes of juvenile mud crab Scylla paramamosain by Jiahao Liu, Jiahao Liu, Jiahao Liu, Jiahao Liu, Shujian Chen, Shujian Chen, Shujian Chen, Zhiming Ren, Zhiming Ren, Zhiming Ren, Yangfang Ye, Yangfang Ye, Yangfang Ye, Chunlin Wang, Chunlin Wang, Chunlin Wang, Changkao Mu, Changkao Mu, Changkao Mu, Qingyang Wu, Qingyang Wu, Qingyang Wu, Ce Shi, Ce Shi, Ce Shi, Ce Shi

“…The crab in SF and MF had a shorter, but LF had a longer molt interval compared with the crab in the CT group. Cortisol, blood glucose (GLU), total cholesterol (T-CHO) and triglyceride (TG) levels peaked in the LF group. …”
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PSGL-1 attenuates early TCR signaling to suppress CD8+ T cell progenitor differentiation and elicit terminal CD8+ T cell exhaustion by Jennifer L. Hope, Dennis C. Otero, Eun-Ah Bae, Christopher J. Stairiker, Ashley B. Palete, Hannah A. Faso, Michelle Lin, Monique L. Henriquez, Sreeja Roy, Hyungseok Seo, Xue Lei, Eric S. Wang, Savio Chow, Roberto Tinoco, Gregory A. Daniels, Kevin Yip, Alexandre Rosa Campos, Jun Yin, Peter D. Adams, Anjana Rao, Linda M. Bradley

“…PSGL-1 deficiency empowers CD8+ T cells to respond to low-affinity TCR ligands and inhibit growth of PD-1-blockade-resistant melanoma by enabling tumor-infiltrating T cells to sustain an elevated metabolic gene signature supportive of increased glycolysis and glucose uptake to promote effector function. This outcome is coupled to an increased abundance of CD8+ T cell stem cell-like progenitors that maintain effector functions. …”
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Efficacy and safety of umbilical cord-derived mesenchymal stem cells in Chinese adults with type 2 diabetes: a single-center, double-blinded, randomized, placebo-controlled phase I... by Li Zang, Yijun Li, Haojie Hao, Jiejie Liu, Yu Cheng, Bing Li, Yaqi Yin, Qian Zhang, Fei Gao, Haibin Wang, Shi Gu, Jia Li, Fengxiang Lin, Yingfei Zhu, Guanglei Tian, Yulong Chen, Weijun Gu, Jin Du, Kang Chen, Qinghua Guo, Guoqing Yang, Yu Pei, Wenhua Yan, Xianling Wang, Junhua Meng, Saichun Zhang, Jianming Ba, Zhaohui Lyu, Jingtao Dou, Weidong Han, Yiming Mu

“…The levels of HbA1c decreased 1.31% (9.02 ± 1.27% to 7.52 ± 1.07%, p < 0.01) in the UC-MSCs group, and only 0.63% in the placebo group (8.89 ± 1.11% to 8.19 ± 1.02%, p˃0.05; p = 0.0081 between both groups). The glucose infusion rate (GIR) increased significantly in the UC-MSCs group (from 3.12 to 4.76 mg/min/kg, p < 0.01), whereas no significant change was observed in the placebo group (from 3.26 to 3.60 mg/min/kg, p ˃ 0.05; p < 0.01 between both groups). …”
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National Essential Public Health Services Programs over the Past Decade Research Report Two：Progress and Achievements of the Implementation of National Essential Public Health Serv... by Lili YOU, Jinhong ZHAO, Xinyue CHEN, Linghe YANG, Meicen LIU, Yuting PAN, Siqi ZHANG, Yuanli LIU

“…The blood pressure / blood glucose control rate in the population managed for hypertension / diabetes has increased by 16.84% and 24.69% respectively in the past decade, with an average annual growth rate of 3.28% and 5.56% respectively. …”
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Methylprednisolone therapy induces differential metabolic trajectories in severe COVID-19 patients by Victor I. Mwangi, Rebeca L. A. Netto, Mayla G. S. Borba, Gabriel F. Santos, Gesiane S. Lima, Lucas S. Machado, Michael N. Yakubu, Fernando F. A. Val, Vanderson S. Sampaio, Marco A. Sartim, Hector H. F. Koolen, Allyson G. Costa, Maria C. M. Toméi, Tiago P. Guimarães, Andrea R. Chaves, Boniek G. Vaz, Marcus V. G. Lacerda, Wuelton M. Monteiro, Luiz G. Gardinassi, Gisely C. Melo

“…The metabolic pathways differing between the two groups over time included galactose metabolism, glucose and gluconeogenesis, N-glycan metabolism, and prostaglandin formation from arachidonate. …”
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Influencia del volumen peritoneal residual en los resultados de la prueba de equilibrio peritoneal. Estudio prospectivo by Luis Falcao, Leticia García Gago, Daniela Astudillo, Catuxa Rodríguez Magariños, Marta Blanco Pardo, Ana Rodríguez-Carmona, Miguel Pérez Fontán

“…Method: Following a prospective design, we calculated Vrpre and Vrpost in 116 patients, incident or prevalent on DP, who underwent one or two (n = 27) PET with 3.86/4.25% glucose-based PD solutions and complete drainage at 60 min. …”
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Outdoor artificial light at night exposure and gestational diabetes mellitus: a case–control study by Qi Sun, Qi Sun, Fang Ye, Jing Liu, Jing Liu, Yang Yang, Qin Hui, Yuanmei Chen, Die Liu, Jianning Guo, Chao Wang, Chao Wang, Di Lv, Di Lv, Lijuan Tang, Lijuan Tang, Qi Zhang, Qi Zhang

“…GDM was diagnosed through oral glucose tolerance tests. Conditional logistic regression models were used to evaluate the association between ALAN exposure and GDM risk. …”
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Activation of Systemic Inflammation and Oxidative Stress in Adolescent Girls with Polycystic Ovary Syndrome in Combination with Metabolic Disorders and Excessive Body Weight by Elena Khashchenko, Mikhail Vysokikh, Elena Uvarova, Lyubov Krechetova, Valentina Vtorushina, Tatyana Ivanets, Maria Volodina, Nadezhda Tarasova, Iuliia Sukhanova, Gennady Sukhikh

“…Patients with PCOS were divided into groups according to the presence of metabolic disorders (MD) (impaired glucose tolerance and/or over insulin resistance) and normal weight or excessive weight (NW or OW). …”
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Role of nerve signal transduction and neuroimmune crosstalk in mediating the analgesic effects of acupuncture for neuropathic pain by Yong Chen, Yong Chen, Dan Li, Dan Li, Ningcen Li, PeiYong Loh, Yi Guo, Yi Guo, Yi Guo, Xiyou Hu, Xiyou Hu, Jingyu Zhang, Jingyu Zhang, Baomin Dou, Baomin Dou, Lifen Wang, Lifen Wang, Chaobo Yang, Chaobo Yang, Tao Guo, Tao Guo, Shuangli Chen, Shuangli Chen, Zhen Liu, Zhen Liu, Bo Chen, Bo Chen, Bo Chen, Zelin Chen, Zelin Chen, Zelin Chen

“…Acupuncture also inhibits neuronal glucose metabolism by downregulating mPFC's GLUT-3 and promotes metabolic alterations of the brain, thus exerting an analgesic effect. …”
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Trehalose Attenuates Oxidative Stress and Endoplasmic Reticulum Stress-Mediated Apoptosis in IPEC-J2 Cells Subjected to Heat Stress by Fan Mo, Xu Zhou, Mengting Yang, Leyi Chen, Zhining Tang, Chong Wang, Yanjun Cui

“…The HS-induced ERS response was evidenced by the increased protein expressions of glucose-regulated protein 78 (GRP78) (<i>p</i> < 0.01), eukaryotic translation initiation factor 2α (p-eif2α) (<i>p</i> < 0.01), transcription activator 4 (ATF4) (<i>p</i> < 0.01), and the protein expression of C/EBP homologous protein (CHOP) (<i>p</i> < 0.01), which were the four hallmarks of ERS. …”
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Efficacy and safety of anti-androgens in the management of polycystic ovary syndrome: a systematic review and meta-analysis of randomised controlled trialsResearch in context by Simon Alesi, Maria Forslund, Johanna Melin, Daniela Romualdi, Alexia Peña, Chau Thien Tay, Selma Feldman Witchel, Helena Teede, Aya Mousa

“…In meta-analysis, anti-androgens + lifestyle were superior to metformin + lifestyle for hirsutism (weighted mean difference [WMD] [95% CI]: −1.59 [−3.06, −0.12], p = 0.03; I2 = 74%), SHBG (7.70 nmol/l [0.75, 14.66], p = 0.03; I2 = 0%), fasting insulin and fasting insulin: glucose ratio (−2.11 μU/ml [−3.97, −0.26], p = 0.03; I2 = 0% and −1.12 [−1.44, −0.79], p < 0.0001, I2 = 0%, respectively), but were not superior to placebo + lifestyle for hirsutism (−0.93, [−3.37, 1.51], p = 0.45; I2 = 76%) or SHBG (9.72 nmol/l [−0.71, 20.14], p = 0.07; I2 = 31%). …”
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Oral 24-week probiotics supplementation did not decrease cardiovascular risk markers in patients with biopsy proven NASH: A double-blind placebo-controlled randomized study by Samantha Thifani Alrutz Barcelos, Amanda Souza Silva-Sperb, Helena Abadie Moraes, Larisse Longo, Bruna Concheski de Moura, Matheus Truccolo Michalczuk, Carolina Uribe-Cruz, Carlos Thadeu Schmidt Cerski, Themis Reverbel da Silveira, Valesca Dall'Alba, Mário Reis Álvares-da-Silva

“…Treatment did not promote any clinically significant changes in body mass index or laboratory, including lipid and glucose profile. High CVR patients through atherogenic indexes decreased from baseline in both groups, as well as PAI-1 and miR-122 levels, although there was no difference between probiotics and placebo. …”
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Remission of type 2 diabetes and improved diastolic function by combining structured exercise with meal replacement and food reintroduction among young adults: the RESET for REMISS... by Melanie J Davies, Thomas Yates, Elham Rahme, Gerry P McCann, Joseph Henson, Kaberi Dasgupta, Deborah Chan, Isabel Fortier, Deborah Da Costa, Edward Gregg, Stéphanie Chevalier, Matthew McCarthy, Mark Sherman, Emma Redman, Matthias G Friedrich, Carla M Prado, Richard B Thompson, Michelle Hadjiconstantinou, Abhishek Dattani, Normand Boulé, Julia Champagne, Frank Arsenyadis, Jordan Rees, Roseanne Yeung

“…The primary outcome is T2DM remission, (haemoglobin A1c of less than 6.5% at 24 weeks, without use of glucose-lowering medications during maintenance). …”
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Association between breast nodules, anxiety, depression and metabolic risk factors in a Chinese cohort by Yan Long, Yan Long, Wei Zhang, Wei Zhang, Maolan Zheng, Maolan Zheng, Qian Xie, Qian Xie, He Liu, He Liu, Xiaotong Hu, Xiaotong Hu, Xuelan Zhang, Xuelan Zhang, Wei Huang, Wei Huang, Xia Gao, Xia Gao, Chunmao Jiang, Chunmao Jiang, Can Jiang, Dong Gao, Juan Deng, Juan Deng

“…Serum samples were used to measure fasting blood glucose, uric acid, triglycerides, total cholesterol, urea nitrogen, alanine transaminase, aspartate transaminase, albumin, high-density lipoprotein, low-density lipoprotein. …”
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Predicting depressive symptom by cardiometabolic indicators in mid-aged and older adults in China: a population-based cross-sectional study by Ying Wang, Xiaoyun Zhang, Yuqing Li, Jiaofeng Gui, Yujin Mei, Xue Yang, Haiyang Liu, Lei-lei Guo, Jinlong Li, Yunxiao Lei, Xiaoping Li, Lu Sun, Liu Yang, Ting Yuan, Congzhi Wang, Dongmei Zhang, Jing Li, Mingming Liu, Ying Hua, Lin Zhang

“…The study evaluated the relationship between cardiometabolic indicators and depression by measuring 13 indicators, including body mass index (BMI), waist circumference, waist-height ratio (WHtR), conicity index, visceral adiposity index (VAI), Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), a body shape index (ABSI), body roundness index (BRI), triglyceride glucose index (TyG-index) and its correlation index (TyG-BMI, TyG-waist circumference, TyG-WHtR). …”
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The association between stress hyperglycemia and unfavorable outcomes in patients with anterior circulation stroke after mechanical thrombectomy by Junrun Zhang, Junrun Zhang, Dawei Dong, Dawei Dong, You Zeng, Bing Yang, Bing Yang, Fangze Li, Fangze Li, Xuefang Chen, Xuefang Chen, Jingchong Lu, Jingchong Lu, Min Guan, Min Guan, Niu He, Niu He, Hongyu Qiao, Hongyu Qiao, Keshen Li, Keshen Li, Anding Xu, Anding Xu, Li’an Huang, Li’an Huang, Huili Zhu, Huili Zhu

“…The stress hyperglycemia ratio (SHR) was calculated as fasting plasma glucose (mmol/L) divided by glycosylated hemoglobin (%). …”
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Muscle wasting in patients with end‐stage renal disease or early‐stage lung cancer: common mechanisms at work by Julien Aniort, Alexandre Stella, Carole Philipponnet, Anais Poyet, Cécile Polge, Agnès Claustre, Lydie Combaret, Daniel Béchet, Didier Attaix, Stéphane Boisgard, Marc Filaire, Eugénio Rosset, Odile Burlet‐Schiltz, Anne‐Elisabeth Heng, Daniel Taillandier

“…Functional analysis revealed up to 238 proteins belonging to nine metabolic processes (inflammatory response, proteolysis, cytoskeleton organization, glucose metabolism, muscle contraction, oxidant detoxification, energy metabolism, fatty acid metabolism, and extracellular matrix) involved in and/or altered by the atrophying programme in both LC and HD patients. …”
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