Dysglycemia in young women attenuates the protective effect against fatty liver disease by Alejandra Pérez-Montes de Oca, Alejandra Pérez-Montes de Oca, María Teresa Julián, María Teresa Julián, Guillem Pera, Guillem Pera, Llorenç Caballería, Llorenç Caballería, Rosa Morillas, Rosa Morillas, Pere Torán, Pere Torán, Carmen Expósito, Carmen Expósito, Josep Franch-Nadal, Josep Franch-Nadal, Didac Mauricio, Didac Mauricio, Didac Mauricio, Nuria Alonso, Nuria Alonso, Nuria Alonso

“…Type 2 diabetes mellitus (T2D) significantly increases the risk and severity of NAFLD, but there is scarce information on whether T2D or altered glucose metabolism can modify the prevalence of NAFLD in men and women of reproductive age.PurposeTo investigate the relationship between age, sex and NAFLD in subjects with and without dysglycemia.Materials and methodsWe analyzed 2,790 patients. …”
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Dapagliflozin reduces pulmonary vascular damage and susceptibility to atrial fibrillation in right heart disease by Chang Dai, Bin Kong, Wei Shuai, Zheng Xiao, Tianyou Qin, Jin Fang, Yang Gong, Jun Zhu, Qi Liu, Hui Fu, Hong Meng, He Huang

“…Abstract Aims Sodium‐glucose cotransporter 2 inhibitors (SGLT2is) have made considerable progress in the field of heart failure, but their application in arrhythmia remains to be in‐depth. …”
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Efforts towards the synthesis of fully N-differentiated heparin-like glycosaminoglycans; and, Investigations into the mechanism of inactivation of RTPR by gemcitabine triphosphate by Lohman, Gregory J. S

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Serial histology and blockface images. Full mouse heart, 600 sections by Siedlecka, U, Jones, E, Gruscheski, L, Quinn, T, Kohl, P, Casero, R

“…Mouse hearts were excised after Schedule 1 culling according to the UK Home Office guidance on the Operation of Animals (Scientific Procedures) Act of 1986, washed swiftly in 37°C normal Tyrode solution (NaCl 140 mM; KCl 5.4 mM; MgCl2 1 mM; HEPES 5 mM; Glucose 10 mM; CaCl2 1.8 mM; pH 7.4, 300±10 mOsm) containing heparin (10u/ml) and then cannulated in cold Tyrode solution with heparin in order to perfuse the coronary vasculature from the aorta. …”

Production, characterization and scaling up of monoclonal antibodies against neuraminidase glycoprotein of avian influenza virus subtype H9N2 by Abdelaziz Fadul, Sana Awad

“…The addition of nutrient medium in fed batch process, maintained the continuous supply of nutrients specially glucose and glutamine and kept their by-products lactate and ammonia at low levels, which led to the enhancement of productivity in terms of antibodies concentration, cell density and cell viabilities. …”
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Pullulanase Type 1-Assisted Modification of Sago (Metroxylon sagu) Starch by Wong, Chen Wai

“…Starch is a mixture of two polysaccharides, the linear molecule of amylose, which consists of polymers of glucose, and amylopectin, a highly branched molecule. …”
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Effects of chitin and chitosan extracted from house cricket (Brachytrupes portentosus Lichtenstein) on performance and immune response of broiler chickens by Busayo, Ibitoye E.

“…In addition, relative mRNA expression of oligopeptide transporter (PepT1), excitatory amino acid transporters 3 (EAAT3), Na+-dependent glucose and galactose transporter (SGLT1) and Na+-independent fructose transporter (SGLT5) were determined from the jejunum by real-time PCR. …”
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Factors associated with frailty among postmenopausal Chinese women from selected senior citizen associations in Kuala Lumpur and Selangor, Malaysia by Chan, Kai Sze

“…A total of 5 ml fasting blood samples was drawn for analysis of fasting blood glucose (FBG) and lipid profile to ascertain the presence of metabolic syndrome (MS) among the respondents. …”
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Menstrual abnormalities effects on clinical features and in vitro fertilization pregnancy outcomes in women with polycystic ovarian syndromeAJOG Global Reports at a Glance by Haozhe Miao, MD, Huiming Yang, MD, Mengfei Yin, MD, Yixuan Wang, MD, Yuan Fang, MD, Min Yang, MD, Jialin Zou, MD, Wenwen Zhang, MD, Lingling Zhang, MD, Chendan Liu, MD, Yue Wang, MD, Ze Wang, MD, Yunhai Yu, MD, PhD, Daimin Wei, MD, PhD

“…RESULTS: Compared with the late group, the early group had more antral follicles (32.00 [range, 27.25–39.50] vs 28.00 [range, 24.00–36.00]; P<.001), an elevated level of antimüllerian hormone (7.02 ng/mL [range, 3.60–11.47] vs 5.66 ng/mL [range, 3.65–8.92]; P=.024), a higher level of baseline luteinizing hormone (10.01±5.93 vs 8.51±5.53 IU/l; P<.001) and luteinizing hormone–to–follicle-stimulating hormone ratio (1.51 [range, 1.00–2.32] vs 1.45 [range, 0.92–2.13]; P<.001), lower levels of fasting glucose (5.47 mmol/L [range, 5.11–5.73] vs 5.50 mmol/L [range, 5.17–5.76]; P<.001), and insulin at 2 hours after 75-g oral glucose tolerance test (56.85 µU/mL [range, 34.63–94.54] vs 59.82 µU/mL [range, 33.56–94.67]; P=.027), a higher level of high-density lipoprotein (1.26 mmol/L [range, 1.04–1.37] vs 1.21 mmol/L [range, 1.07–1.45]; P=.006). …”
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Association of acute toxic encephalopathy with litchi consumption in an outbreak in Muzaffarpur, India, 2014: a case-control study by Aakash Shrivastava, PhD, Anil Kumar, MD, Jerry D Thomas, MD, Kayla F Laserson, ScD, Gyan Bhushan, MD, Melissa D Carter, PhD, Mala Chhabra, MD, Veena Mittal, MD, Shashi Khare, MD, James J Sejvar, MD, Mayank Dwivedi, MD, Samantha L Isenberg, PhD, Rudolph Johnson, PhD, James L Pirkle, MD, Jon D Sharer, PhD, Patricia L Hall, PhD, Rajesh Yadav, MBBS, Anoop Velayudhan, MBBS, Mohan Papanna, MD, Pankaj Singh, D Somashekar, MD, Arghya Pradhan, MBBS, Kapil Goel, MD, Rajesh Pandey, MBBS, Mohan Kumar, MBBS, Satish Kumar, MD, Amit Chakrabarti, MD, P Sivaperumal, PhD, A Ramesh Kumar, PhD, Joshua G Schier, MD, Arthur Chang, MD, Leigh Ann Graham, PhD, Thomas P Mathews, PhD, Darryl Johnson, PhD, Liza Valentin, PhD, Kathleen L Caldwell, PhD, Jeffery M Jarrett, MS, Leslie A Harden, MS, Gary R Takeoka, PhD, Suxiang Tong, PhD, Krista Queen, PhD, Clinton Paden, PhD, Anne Whitney, PhD, Dana L Haberling, MSPH, Ram Singh, PhD, Ravi Shankar Singh, MD, Kenneth C Earhart, MD, A C Dhariwal, MD, L S Chauhan, DPH, S Venkatesh, MD, Padmini Srikantiah, DrMD

“…On admission, 204 (62%) of 327 had blood glucose concentration of 70 mg/dL or less. 104 cases were compared with 104 age-matched hospital controls. …”
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A missense variant in human perilipin 2 (PLIN2 Ser251Pro) reduces hepatic steatosis in mice by Eleonora Scorletti, Yedidya Saiman, Sookyoung Jeon, Carolin V. Schneider, Delfin G. Buyco, Chelsea Lin, Blanca E. Himes, Clementina A. Mesaros, Marijana Vujkovic, Kate Townsend Creasy, Emma E. Furth, Jeffrey T. Billheimer, Nicholas J. Hand, David E. Kaplan, Kyong-Mi Chang, Philip S. Tsao, Julie A. Lynch, Joseph L. Dempsey, Julia Harkin, Susovon Bayen, Donna Conlon, Marie Guerraty, Michael C. Phillips, Daniel J. Rader, Rotonya M. Carr

“…PLIN2-Pro251 attenuates liver triglycerides accumulation after a high-fat-high-glucose-diet. PLIN2-Pro251 may be a novel lipid droplet protein target for the treatment of liver steatosis.…”
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The Effect of Using Different Fat Sources in Close-Up Diets on the Feed Consumption, Blood Parameters, Body Measurements and Performance of Holstein Dairy Calves by Mahmoodreza Amini, Abbas Ali Naserian, Reza Valizadeh, Essa Dirandeh

“…Our results showed that blood factors such as glucose, cholesterol, triglycerides, blood urea nitrogen, ALT, AST, total antioxidant capacity, malondialdehyde, total protein, albumin, calcium, magnesium, phosphorus, and HDL did not differ between treatments. …”
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Evidence of a causal and modifiable relationship between kidney function and circulating trimethylamine N-oxide by Petros Andrikopoulos, Judith Aron-Wisnewsky, Rima Chakaroun, Antonis Myridakis, Sofia K. Forslund, Trine Nielsen, Solia Adriouch, Bridget Holmes, Julien Chilloux, Sara Vieira-Silva, Gwen Falony, Joe-Elie Salem, Fabrizio Andreelli, Eugeni Belda, Julius Kieswich, Kanta Chechi, Francesc Puig-Castellvi, Mickael Chevalier, Emmanuelle Le Chatelier, Michael T. Olanipekun, Lesley Hoyles, Renato Alves, Gerard Helft, Richard Isnard, Lars Køber, Luis Pedro Coelho, Christine Rouault, Dominique Gauguier, Jens Peter Gøtze, Edi Prifti, Philippe Froguel, The MetaCardis Consortium, Jean-Daniel Zucker, Fredrik Bäckhed, Henrik Vestergaard, Torben Hansen, Jean-Michel Oppert, Matthias Blüher, Jens Nielsen, Jeroen Raes, Peer Bork, Muhammad M. Yaqoob, Michael Stumvoll, Oluf Pedersen, S. Dusko Ehrlich, Karine Clément, Marc-Emmanuel Dumas

“…Consistent with our findings, patients receiving glucose-lowering drugs with reno-protective properties have significantly lower circulating TMAO when compared to propensity-score matched control individuals. …”
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Retrospective Analysis of Experimental and Clinical Studies of Flakozid in Viral Hepatitis by V. V. Karabaeva, L. V. Krepkova, A. N. Babenko, V. V. Bortnikova, T. V. Fateeva, P. G. Mizina, N. S. Mikheeva, O. N. Karabaeva

“…"Flakozid" was prescribed against the background of basic therapy: diet and detoxification therapy: 5 % glucose solution, 5 % ascorbic acid solution, "Hemodesi", at a daily dose of 0,3–0,8 g for up to 38 days. …”
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2335 by Alexa Kanwit Craig

“…Laboratory data points included serum creatinine level, serum glucose level, liver function tests (AST and ALT), platelet count, hematocrit level, PTT, INR, fibrinogen, white blood cell count and lactate. …”
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Study of Germination Characteristics of Fenugreek (Trigonella foenum-graecum L.) population under Salinity and Drought Stress by hassan Farhadi, majid Azizi, hossein Nemati

“…Introduction: Fenugreek (Trigonalla foenum-graecum L.), an annual herbaceous plant belonging to the Coleoidea (Fabaceae) family, has numerous medicinal properties such as decreasing blood glucose, laxative, appetizer, mucus, antipyretic and increasing the amount of milk during lactation . …”
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A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy by Feifei Guo, Olga Estévez-Vázquez, Raquel Benedé-Ubieto, Douglas Maya-Miles, Kang Zheng, Rocío Gallego-Durán, Ángela Rojas, Javier Ampuero, Manuel Romero-Gómez, Kaye Philip, Isioma U. Egbuniwe, Chaobo Chen, Jorge Simon, Teresa C. Delgado, María Luz Martínez-Chantar, Jie Sun, Johanna Reissing, Tony Bruns, Arantza Lamas-Paz, Manuel Gómez del Moral, Marius Maximilian Woitok, Javier Vaquero, José R. Regueiro, Christian Liedtke, Christian Trautwein, Rafael Bañares, Francisco Javier Cubero, Yulia A. Nevzorova

“…Results: Mild obesity, spontaneous hyperlipidaemia, glucose intolerance and insulin resistance were characteristic of 36-week-old alb-myc^tg mice. …”
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Global miRNA expression reveals novel nuclear and mitochondrial interactions in Type 1 diabetes mellitus by Rafaella Sousa Ferraz, Lucas Cauê Bezerra Santos, Rebecca Lais da-Silva-Cruz, Cintia Helena Braga-da-Silva, Leandro Magalhães, Arthur Ribeiro-dos-Santos, Amanda Vidal, Amanda Vidal, Tatiana Vinasco-Sandoval, Laís Reis-das-Mercês, Camille Sena-dos-Santos, Adenilson Leão Pereira, Lilian Souza D’Albuquerque Silva, Franciane T. Cunha de Melo, Ana Carolina C. Braga de Souza, Valéria S. Galvão Leal, Priscila B. Barbosa de Figueiredo, João F. Abrahão Neto, Lorena Vilhena de Moraes, Gabriela Nascimento de Lemos, Natércia Neves Marques de Queiroz, Karem Miléo Felício, Giovanna C. Cavalcante, Ândrea Ribeiro-dos-Santos, Ândrea Ribeiro-dos-Santos, João Soares Felício

“…BackgroundConsidering the potential role of miRNAs as biomarkers and their interaction with both nuclear and mitochondrial genes, we investigated the miRNA expression profile in type 1 diabetes (T1DM) patients, including the pathways in which they are involved considering both nuclear and mitochondrial functions.MethodsWe analyzed samples of T1DM patients and control individuals (normal glucose tolerance) by high throughput miRNA sequencing (miRNome). …”
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Evaluation of hepatic AMPK, mTORC1, and autophagy-lysosomal pathway in cows with mild or moderate fatty liver by Xiliang Du, Meng Chen, Zhiyuan Fang, Qi Shao, Hao Yu, Xue Hao, Xinxing Gao, Lingxue Ju, Chenxu Li, Yuting Yang, Yuxiang Song, Lin Lei, Guowen Liu, Xinwei Li

“…Blood concentrations of glucose were lower in moderate FL cows (3.03 ± 0.21 mM) than in healthy (3.71 ± 0.14 mM) and mild FL cows (3.76 ± 0.14 mM). …”
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Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations by Triana Espinosa-Jiménez, Triana Espinosa-Jiménez, Triana Espinosa-Jiménez, Oriol Busquets, Amanda Cano, Amanda Cano, Amanda Cano, Amanda Cano, Elena Sánchez-López, Elena Sánchez-López, Elena Sánchez-López, Elena Sánchez-López, Ester Verdaguer, Ester Verdaguer, Ester Verdaguer, Antoni Parcerisas, Jordi Olloquequi, Carme Auladell, Carme Auladell, Carme Auladell, Jaume Folch, Jaume Folch, Walter Wahli, Walter Wahli, Walter Wahli, Manuel Vázquez-Carrera, Manuel Vázquez-Carrera, Manuel Vázquez-Carrera, Antoni Camins, Antoni Camins, Antoni Camins, Miren Ettcheto, Miren Ettcheto, Miren Ettcheto

“…Before sacrifice, novel object recognition test (NORT) and glucose and insulin tolerance tests were performed. …”
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