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52021
From gut to liver: unveiling the differences of intestinal microbiota in NAFL and NASH patients
Published 2024-04-01“…Furthermore, KEGG pathway analysis highlighted significant disturbances in various types of glucose metabolism pathways in the NASH group compared to the NAFL group, as well as notably compromised flavonoid and flavonol biosynthesis functions. …”
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52022
The iHealth-T2D study, prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes: study protocol for a randomised controlled trial
Published 2021-12-01“…Secondary endpoints at 1 and 3 years are the following: (i) physical measures: waist circumference, weight and blood pressure; (ii) lifestyle measures: smoking status, alcohol intake, physical activity and dietary intake; (iii) biochemical measures: fasting glucose, insulin and lipids (total and HDL cholesterol, triglycerides); and (iv) treatment compliance. …”
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52023
Effects of Glucocorticoids on Postoperative Neurocognitive Disorders in Adult Patients: A Systematic Review and Meta-Analysis
Published 2022-06-01“…However, there were no significant differences between groups with regards to the incidence of postoperative infection (RR: 0.94, 95% CI: 0.84 to 1.06, P = 0.30, GRADE = moderate), blood glucose level (RR: 1.05, 95% CI: −0.09 to 2.19, P = 0.07, GRADE = low), duration of mechanical ventilation (RR: −2.44, 95% CI: −5.47 to 0.59, P = 0.14, GRADE = low), length of hospital stay (RR: −0.09, 95% CI: −0.27 to 0.09, P = 0.33, GRADE = moderate) and 30-day mortality (RR: 0.86, 95% CI: 0.70 to 1.06, P = 0.16, GRADE = moderate).ConclusionsThis meta-analysis suggests that perioperative administration of glucocorticoids may not reduce the incidence of PNDs after surgery. …”
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52024
Racial and Ethnic Differences in the Association Between Classical Cardiovascular Risk Factors and Common Carotid Intima‐Media Thickness: An Individual Participant Data Meta‐Analys...
Published 2022-08-01“…Smoking (beta coefficient, 0.39; 95% CI, 0.09–0.70), body mass index (beta coefficient, 0.05; 95% CI, 0.01–0.08) and glucose (beta coefficient, 0.13; 95% CI, 0.06–0.19) had the strongest positive association with CIMT in the Asian population when compared with all other racial and ethnic groups. …”
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52025
Apigetrin-enriched Pulmeria alba extract prevents assault of STZ on pancreatic β-cells and neuronal oxidative stress with concomitant attenuation of tissue damage and suppression o...
Published 2023-06-01“…Our in vitro studies revealed dose-dependent increased glucose uptake and inhibition of α-amylase (50% inhibitory concentration (IC50)= 217.19 µg/mL), antioxidant (DPPH, ferric-reducing activity of plasma (FRAP), and lipid peroxidation (LPO) [IC50 = 103.23, 58.72, and 114.16 µg/mL respectively]), and anti-inflammatory potential (stabilizes human red blood cell (HRBC) membranes, and inhibits proteinase and protein denaturation [IC50 = 143.73, 131.63, and 198.57 µg/mL]) by the PAm extract. …”
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52026
Associations and pathways between residential greenness and metabolic syndromes in Fujian Province
Published 2022-12-01“…MetS was defined as the presence of three or more of the five components: abdominal obesity, elevated triglyceride, reduced high-density lipoprotein cholesterol (HDL-C), high blood pressure, and elevated fasting glucose. The residential greenness exposure was measured as the 3-year mean values of the normalized difference vegetation index (NDVI) and enhanced vegetation index (EVI) within the 250, 500, and 1,000 meters (m) buffer zones around the residential address of each participant. …”
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52027
Obesity- and lipid-related indices as a predictor of obesity metabolic syndrome in a national cohort study
Published 2023-02-01“…A total of 13 obesity- and lipid-related indices, including body mass index (BMI), waist circumference (WC), waist-to-height ratio (WHtR), conicity index (CI), visceral adiposity index (VAI), Chinese visceral adiposity index (CVAI), lipid accumulation product (LAP), a body shape index (ABSI), body roundness index (BRI), and triglyceride glucose index (TyG-index) and its correlation index (TyG-BMI, TyG-WC, and TyG-WHtR), were recorded. …”
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52028
Clinical feasibility study of early 30-minute dynamic FDG-PET scanning protocol for patients with lung lesions
Published 2024-03-01“…Abstract Purpose This study aimed to evaluate the clinical feasibility of early 30-minute dynamic 2-deoxy-2-[18F]fluoro-D-glucose (18F-FDG) positron emission tomography (PET) scanning protocol for patients with lung lesions in comparison to the standard 65-minute dynamic FDG-PET scanning as a reference. …”
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52029
Setanaxib mitigates oxidative damage following retinal ischemia-reperfusion via NOX1 and NOX4 inhibition in retinal ganglion cells
Published 2024-01-01“…The model of retinal I/R induced by acute intraocular hypertension and the oxygen-glucose deprivation/reoxygenation (OGD/R) model of primary RGCs were established. …”
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52030
A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells
Published 2023-02-01“…Diminished LncTGM2 in human beta cells impairs glucose-stimulated insulin release.ConclusionsThese findings provide novel information on the molecular mechanisms by which T2D-associated SNPs in lncRNAs may contribute to disease, paving the way for the development of new therapies based on the modulation of lncRNAs.…”
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52031
Inhibiting G6PD by quercetin promotes degradation of EGFR T790M mutation
Published 2023-11-01“…In this study, we show that quercetin directly binds with glucose-6-phosphate dehydrogenase (G6PD) and inhibits its enzymatic activity through competitively abrogating NADP+ binding in the catalytic domain. …”
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52032
The prevalence of MAFLD and its association with atrial fibrillation in a nationwide health check-up population in China
Published 2022-09-01“…In addition, the coexistence of prediabetes or diabetes had the largest impact on subsequent AF.ConclusionOur findings suggested a high prevalence of MAFLD and a high prevalence of other metabolic diseases in the MAFLD population, particularly overweight and glucose dysregulation. Moreover, MAFLD was associated with a significantly higher risk for existing and subsequent subclinical AF in the Chinese population.…”
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52033
A specific gut microbiota signature is associated with an enhanced GLP-1 and GLP-2 secretion and improved metabolic control in patients with type 2 diabetes after metabolic Roux-en...
Published 2023-10-01“…Species belonging to Streptococaceae, Akkermansiacea, Rickenellaceae, Sutterellaceae, Enterobacteriaceae, Oscillospiraceae, Veillonellaceae, Enterobacterales_uc, and Fusobacteriaceae families increased after intervention and correlated positively with AUC of GLP-1 and GLP-2, and negatively with glucose, HbA1c, triglycerides and adiposity markers. …”
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52034
The iHealth-T2D study, prevention of type 2 diabetes amongst South Asians with central obesity and prediabetes: study protocol for a randomised controlled trial
Published 2022“…Secondary endpoints at 1 and 3 years are the following: (i) physical measures: waist circumference, weight and blood pressure; (ii) lifestyle measures: smoking status, alcohol intake, physical activity and dietary intake; (iii) biochemical measures: fasting glucose, insulin and lipids (total and HDL cholesterol, triglycerides); and (iv) treatment compliance. …”
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Journal Article -
52035
Role of cell-cell signaling, differentiation and fitness in multi-species biofilms
Published 2015“…The proportions and structures of the three bacterial species within the mixed species biofilms grown at the inlet end and outlet end of the continuous-culture flow cell also differed, most likely as a result of decreasing glucose concentration and associated changes in the specific growth rate for KP-1 along the channel. …”
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Thesis -
52036
Interactive telemedicine: effects on professional practice and health care outcomes
Published 2015“…Studies recruiting participants requiring mental health services and those requiring specialist consultation for a dermatological condition reported no differences between groups.The findings in our review indicate that the use of TM in the management of heart failure appears to lead to similar health outcomes as face-to-face or telephone delivery of care; there is evidence that TM can improve the control of blood glucose in those with diabetes. The cost to a health service, and acceptability by patients and healthcare professionals, is not clear due to limited data reported for these outcomes. …”
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52037
Effectiveness of practice guidelines nutritional care and basic nutritional care on anthropometric and metabolic outcomes in type 2 diabetes mellitus patients at Sultan Qaboos Univ...
Published 2013“…Anthropometric (weight, height, BMI and waist circumference), biochemical (fasting blood glucose, HbA1c, triglycerides, cholesterol, LDL cholesterol and HDL cholesterol), dietary intake (total energy, carbohydrate, fat, cholesterol, saturated fatty acids, monounsaturated fatty acids and polyunsaturated fatty acids) and physical activity (total physical activity MET-minutes/week, walking MET-minutes/week,moderate MET-minutes/week and vigorous MET-minutes/week) variables were measured at three time points (0, 3, 6 months). …”
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Thesis -
52038
Evaluation of diabetic wound healing properties of moringa oleifera lam using in vitro and in vivo wound models
Published 2015“…Following induction of diabetes by STZ-NAD in Wistar rats, hyperglycemia was maintained for 21 days and the reading of blood glucose level was more significant in diabetic groups compared to normal control group (p < 0.05). …”
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Thesis -
52039
Chemical profiling of Cosmos caudatus Kunth possessing antioxidant and α-glucosidase inhibitory activity
Published 2017“…It’s showed that the flavonoids glycosides were the responsible compounds that contribute to the free radical scavenging and lowering the glucose effects of C. caudatus leaves. Interestingly, in the present study, quercetin 3-O-xyloside in C. caudatus extracts was reported for the first time. …”
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Thesis -
52040
Proximate composition, starch properties and functionality in selected aquatic macrophytes
Published 2019“…Non-starch components like protein was high in most starches (3.06-26.47%) as well as lipid contents (0.24-5.57%) affected the starch purities, whereas phosphorus contents (0.02-0.43%) association with starch increased the starch functionality. Glucose was present in all of the samples range between 0.19 g 100 g-1 - 0.25 g 100 g-1. …”
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Thesis