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52181
Functional and structural analysis of double and triple mutants reveals the contribution of protein instability to clinical manifestations of G6PD variants
Published 2020“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common polymorphism and enzymopathy in humans, affecting approximately 400 million people worldwide. …”
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52182
Validation of the quantitative point-of-care CareStart biosensor for assessment of G6PD activity in venous blood
Published 2018“…Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymopathy in the human population affecting an estimated 8% of the world population, especially those living in areas of past and present malaria endemicity. …”
Journal article -
52183
Modelling incremental benefits on complications rates when targeting lower HbA1c levels in people with Type 2 diabetes and cardiovascular disease
Published 2017“…Glucose-lowering interventions in Type 2 diabetes mellitus have demonstrated reductions in microvascular complications and modest reductions in macrovascular complications. …”
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52184
The Effect of the Enteral Correction Program on Oxidative Stress Parameters in Patients with Poisoning with Psychopharmacological Agents or Corrosive Substances
Published 2022-04-01“…The ECP included making intestinal lavage on admission, the introduction of glucosed saline enteral solution in the following days; and for patients with PCS the treatment also included enteral nutrition and Pektovit.The comparison groups included 56 people (34 with PCS and 22 with PPPA) comparable to the patients of the study groups by sex, age, the type and severity of poisoning poisoning treated with standard therapy The severity of OS was assessed by the KMDA/TAA index which was calculated by means of measuring the concentration of malonic dialdehyde (as an LPO parameter) and total antioxidant activity in the blood plasma of the patients. …”
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