ANTIHIPERURESEMIA FLAVONOID DARI EKSTRAK ETANOL PELEPAH DAUN NIPAH (Nypa fruticans.Wurmb) by Danang Raharjo, Anita Dwi S, Bagas Ardiyantoro

“… Hiperuresimia atau asam urat pada stadium lanjut menyebabkan kerusakan sendi (gout), batu ginjal dan kerusakan ginjal. Flavonoid sebagai antioksidan dapat menghambat aktivitas enzim xantin oksidase yang menyebabkan asam urat tidak terbentuk. …”
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Chronic Disease Prevalence. A perspective using Administrative Data from Australia by Shaun Purkiss, Tessa Keegal, Dennis Wollersheim, Hassan Vally

“…PBS prevalence estimates of diabetes, gout and asthma showed respective correlations of 0.999, 0.8385 and 0.58 to 0.82 with community surveys. …”
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Nonapnea Sleep Disorders in Patients Younger than 65 Years Are Significantly Associated with CKD: A Nationwide Population-Based Study. by Hugo You-Hsien Lin, Chi-Chih Hung, Yu-Han Chang, Ming-Yen Lin, Ming-Yu Yang, Shih-Shin Liang, Wangta Liu, Hung-Chun Chen, Shang-Jyh Hwang

“…Men, older age, type 2 diabetes mellitus, and gout were significant factors associated with the increased risk of CKD (p< 0.001). …”
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Interleukin-1, inflammasomes, autoinflammation and the skin by Emmanuel Contassot, Hans-Dietmar Beer, Lars E. French

“…The inflammasomes, recently identified innate immune complexes that sense intracellular danger- (e.g. uric acid, ATP, cytoplasmic DNA) or pathogen-associated molecular patterns (e.g. muramyl dipeptide, flagellin, anthrax lethal toxin), are now known to be responsible for triggering inflammation in response to several molecular patterns, including, for example, uric acid, a danger-associated molecular pattern and trigger of gout. Dysregulation of inflammasome function is however also the cause of a family of genetic autoinflammatory diseases known as cryopyrin-associated periodic syndromes (CAPS) characterised by recurrent episodes of fever, urticarial-like skin lesions, systemic inflammation and arthritis. …”
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Notes sur « la charpente secrète » et sur la thématique de L’Automne du patriarche de G. García Márquez by Richard Renaud

“…Les trois autres s’articulent autour de la bassesse du protagoniste, mise en évidence par sa duplicité – qu’exprime le thème du double ou du miroir (chapitre I) ; par sa corruption (chapitre III) ; et par un goût infantile du pouvoir qui le pousse à vendre les eaux territoriales afin d’éviter une nouvelle occupation du pays par une puissance étrangère dominatrice (chapitre VI).…”
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The Artificial Intelligence System for the Generation of Sports Education Guidance Model and Physical Fitness Evaluation Under Deep Learning by Yuanqing Li, Yuanqing Li, Xiangliang Li

“…The highest incidence of female gynecological diseases was gout (23.0%) and hyperlipidemia (20.6%). After exercise therapy, the scores were excellent and good. …”
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A rare presentation of late diagnosis of tuberculosis tenosynovitis of flexor tendons of the hand: Case report by Vikramaditya Rai, Sachin Mahendrakumar Chaudhary, Suraj Arungiri Gosai

“…It imitates several different clinical illnesses, including ganglion, De Quervan's disease, carpal tunnel syndrome, granulomatous gout, neurofibroma, and haemangioma. Case report: We present case of a 27-year-old female patient with three years of right hand pain, swelling, and limited finger movement. …”
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Risk factors for intrahepatic and extrahepatic cholangiocarcinoma in the United States: A population-based study in SEER-Medicare. by Jessica L Petrick, Baiyu Yang, Sean F Altekruse, Alison L Van Dyke, Jill Koshiol, Barry I Graubard, Katherine A McGlynn

“…Several autoimmune/inflammatory conditions, including type 1 diabetes and gout, were associated with increased risks of ICC/ECC. …”
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EFFECT OF PRESSURE LIQUID EXTRACTION AND ULTRASONIC IRRADIATION FREQUENCY ON INULIN, PHENOLIC CONTENT AND ANTIOXIDANT ACTIVITY IN BURDOCK (Arctium lappa L.)... by Nadezhda Petkova, Ivan Ivanov, Dasha Mihaylova, Anna Lante

“… Burdock (Arctium lappa L.) roots are traditionally used in folk medicine as diuretic and curing rheumatism, gastritis, gout, throat pain, arthritis and rashes. These pharmacological properties are due to many bioactive compounds such as flavonoids and fructooligosaccharides. …”
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The regulatory role and therapeutic application of pyroptosis in musculoskeletal diseases by Siyu Wang, Hua Wang, Chengyao Feng, Chenbei Li, Zhihong Li, Jieyu He, Chao Tu

“…Next, we elaborated on the role of pyroptosis in some MSDs, including osteoarthritis, rheumatoid arthritis, osteoporosis, gout arthritis, ankylosing spondylitis, intervertebral disc degeneration, and several muscle disorders. …”
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La ponctuation dans quelques imprimés de Galliot du Pré by Huei-Chen LI

“…Comme nous le savons bien, la ponctuation a pour principale fonction de rendre le texte plus intelligible et d’aider le lecteur à repérer le sens des phrases et la structure du texte : cette fonction de rendre le texte clair répond parfaitement au goût des humanistes. Pourtant, face à l’anarchie et à la variabilité de la ponctuation médiévale, la pratique de la ponctuation renaissante, avec l’avènement de l’imprimerie, est-elle plus stable que celle du Moyen Âge ? …”
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Screening and identification of purine degrading Lactobacillus fermentum 9-4 from Chinese fermented rice-flour noodles by Lianghua Lu, Tiantian Liu, Xiaoling Liu, Chenghua Wang

“…The aim of this study was to isolate a new purine-degrading potential probiotic strain from Chinese fermented rice-flour noodles and investigate its potential application in purine-degrading food development for promising anti-gout therapy. A new lactic acid bacteria strain designated as Lactobacillus fermentum 9-4 was screened out from 10 Shengzhamifen samples by a comprehensive method integrating agar plate selection, in vitro purine-metabolizing enzymatic activities of xanthine oxidase and urate oxidase, 16S rRNA gene sequencing and identification. …”
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Phytochemical Analysis and Anti-Inflammatory Activity of The Combination of Trigona apicalis propolis Extract and Honey by Paula Mariana Kustiawan, Chaerul Fadly Mochtar Luthfi M, Sinta Ratna Dewi, Jati Pratiwi, Novia Misnawati Aisyiyah, Alfin Syahrian Dwi Nugraha, Irfan Muris Setiawan

“… Chronic inflammation is common in infectious diseases, rheumatoid arthritis, gout, and autoimmune diseases. However, using non-steroidal anti-inflammatory drugs (NSAIDs) is accompanied by dangerous side effects. …”
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Antihyperuricemic activity and inhibition mechanism of xanthine oxidase inhibitory peptides derived from whey protein by virtual screening by Yaru Xu, Han Gong, Yang Zou, Xueying Mao

“…ABSTRACT: Xanthine oxidase (XO), a rate-limiting enzyme in uric acid production, is the pivotal therapeutic target for gout and hyperuricemia. In this study, 57 peptides from α-lactalbumin and β-lactoglobulin were obtained via virtual enzymatic hydrolysis, and 10 XO inhibitory peptides were virtually screened using molecular docking. …”
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Uric acid and metabolic syndrome: Findings from national health and nutrition examination survey by Rodney G. Bowden, Kathleen A. Richardson, Luke T. Richardson

“…IntroductionHyperuricemia commonly associated with Gout has been proposed as an independent risk factor for Metabolic Syndrome (MetS).ObjectiveThe purpose of the study was to determine if there is a relationship between hyperuricemia and MetS.MethodsAn analysis of cross-sectional data was conducted using the 2013–2018 National Health and Nutrition Examination Survey (NHANES) datasets. …”
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Anti-inflammatory effect of Dieffenbachia standleyi Croat extract on lipopolysaccharide-stimulated murine macrophages by Hyunjun Jang, Wan-Hoon Kim, Bo Kyeong Kim, Ki-Uk Kim, Jisu Kim, Kang Bin Dan, Eunsu Lim, Indiana Maria Coronado, Dong-Keun Yi, Hyeyoung Min

“…Dieffenbachia was used as a folk remedy to prevent inflammation and treat gout, erectile dysfunction, and coldness. Thus, this study investigates the pharmacological function of Dieffenbachia standleyi Croat's methanol extract (DSE). …”
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Bioactive Compounds in Garlic (<i>Allium sativum</i>) and Black Garlic as Antigout Agents, Using Computer Simulation by Ayu Rahmania Lestari, Irmanida Batubara, Setyanto Tri Wahyudi, Auliya Ilmiawati, Suminar Setiati Achmadi

“…Uric acid, which causes gout, is the end product of purine catabolism, synthesized by xanthine oxidase, guanine deaminase, adenine deaminase, purine nucleoside phosphorylase, and 5-nucleotidase II. …”
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<it>Arctium lappa</it> ameliorates endothelial dysfunction in rats fed with high fat/cholesterol diets by Lee Yun, Choi Deok, Cho Guk, Kim Jin, Kang Dae, Lee Ho

“…(Asteraceae), burdock, is a medicinal plant that is popularly used for treating hypertension, gout, hepatitis, and other inflammatory disorders. …”
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Giovanni Niccolò Servandoni: his early education among Florence, Rome and London by Francesco Guidoboni

“…Thanks to this research, Servandoni's complete work - so vaguely interpreted as an anticipation of the “goût à la grecque” and the revival of classicism of the late eighteenth century - is reinterpreted as the result of his training in Italy and England. …”
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Revisiting the inhibitory potential of protein kinase inhibitors against NEK7 protein via comprehensive computational investigations by Syeda Abida Ejaz, Mubashir Aziz, Zeenat Zafar, Naveed Akhtar, Hanan A. Ogaly

“…The aberrant expression of NEK7 has been implicated to the growth of metastasis and severe inflammatory conditions like rheumatoid arthritis, liver cirrhosis, and gout. An emergent target for the development of anti-cancer drugs is NEK7. …”
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