Genome-wide study of familial juvenile hyperuricaemic (gouty) nephropathy (FJHN) indicates a new locus, FJHN3, linked to chromosome 2p22.1-p21 by Piret, SE, Danoy, P, Dahan, K, Reed, A, Pryce, K, Wong, W, Torres, R, Puig, J, Müller, T, Kotanko, P, Lhotta, K, Devuyst, O, Brown, M, Thakker, R

“…FJHN3 is likely located within a ~5.5 Mbp interval on chromosome 2p22.1-p21, and identifying the genetic abnormality will help to further elucidate mechanisms predisposing to gout and renal failure. © 2010 Springer-Verlag.…”

Optimisation of solid-liquid extraction of bioactive compounds from Orthosiphon stamineus benth leaves by Abdul Razak, Mohd Farhan

“…O. stamineus leaves were used in plenty of applications related to the medicinal purposes and are believed to cure certain disease such as hypertension, gout and fever. However, very little research done with regards to ascertain optimum extraction process and quality extract of O. stamineus leaves. …”
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Molecular characterization and pathogenicity of novel Malaysian chicken astrovirus isolates by Abdullahi Raji, Abdullahi, Ideris, Aini, Bejo, Mohd Hair, Omar, Abdul Rahman

“…Chicken astrovirus (CAstV) has for over a decade been associated with runting stunting syndrome, severe kidney disease and visceral gout, and white chick syndrome. However, knowledge of the molecular characteristics and pathogenicity of the virus in day-old specific pathogen-free (SPF) chicks is scarce. …”

Epigenome-wide association study of serum urate reveals insights into urate co-regulation and the SLC2A9 locus by Tin, Adrienne, Schlosser, Pascal, Matias-Garcia, Pamela R., Thio, Chris H. L., Joehanes, Roby, Liu, Hongbo, Yu, Zhi, Weihs, Antoine, Hoppmann, Anselm, Grundner-Culemann, Franziska, Min, Josine L., Kuhns, Victoria L. Halperin, Adeyemo, Adebowale A., Agyemang, Charles, Ärnlöv, Johan, Aziz, Nasir A., Baccarelli, Andrea, Bochud, Murielle, Brenner, Hermann, Bressler, Jan, Breteler, Monique M. B., Carmeli, Cristian, Chaker, Layal, Coresh, Josef, Corre, Tanguy, Correa, Adolfo, Cox, Simon R., Delgado, Graciela E., Eckardt, Kai-Uwe, Ekici, Arif B., Endlich, Karlhans, Floyd, James S., Fraszczyk, Eliza, Gao, Xu, Gào, Xīn, Gelber, Allan C., Ghanbari, Mohsen, Ghasemi, Sahar, Gieger, Christian, Greenland, Philip, Grove, Megan L., Harris, Sarah E., Hemani, Gibran, Henneman, Peter, Herder, Christian, Horvath, Steve, Hou, Lifang, Hurme, Mikko A., Hwang, Shih-Jen, Kardia, Sharon L. R., Kasela, Silva, Kleber, Marcus E., Koenig, Wolfgang, Kooner, Jaspal S., Kronenberg, Florian, Kühnel, Brigitte, Ladd-Acosta, Christine, Lehtimäki, Terho, Lind, Lars, Liu, Dan, Lloyd-Jones, Donald M., Lorkowski, Stefan, Lu, Ake T., Marioni, Riccardo E., März, Winfried, McCartney, Daniel L., Meeks, Karlijn A. C., Milani, Lili, Mishra, Pashupati P., Nauck, Matthias, Nowak, Christoph, Peters, Annette, Prokisch, Holger, Psaty, Bruce M., Raitakari, Olli T., Ratliff, Scott M., Reiner, Alex P., Schöttker, Ben, Schwartz, Joel, Sedaghat, Sanaz, Smith, Jennifer A., Sotoodehnia, Nona, Stocker, Hannah R., Stringhini, Silvia, Sundström, Johan, Swenson, Brenton R., van Meurs, Joyce B. J., van Vliet-Ostaptchouk, Jana V., Venema, Andrea, Völker, Uwe, Winkelmann, Juliane, Wolffenbuttel, Bruce H. R., Zhao, Wei, Zheng, Yinan, Milani, Lili, Esko, Tõnu, Metspalu, Andres, Mägi, Reedik, Nelis, Mari, Min, Josine L., Hemani, Gibran, Loh, Marie, Snieder, Harold, Waldenberger, Melanie, Levy, Daniel, Akilesh, Shreeram, Woodward, Owen M., Susztak, Katalin, Teumer, Alexander, Köttgen, Anna

“…Elevated serum urate levels, a complex trait and major risk factor for incident gout, are correlated with cardiometabolic traits via incompletely understood mechanisms. …”
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Optimisation of Solid Liquid Extraction of Orthosiphon stamineus Leaves using Response Surface Methodology Technique by A. R., Mohd Farhan, K. Y., Pin, M. S., Zamree, Luqman Chuah, Abdullah, Nazira, Mahmud

“…stamineus leaves are used in numerous applications related to medicinal purposes and are believed to cure certain health conditions such as hypertension, gout and fever. The aim of this study was to investigate the effect of three parameters involved in extraction process including extraction temperature, extraction duration and solvent to solid ratio on extraction yield, antioxidant activity and referral markers of O. stamineus leaves. …”
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UV detection on artificial uric acid using UV-Vis spectrometer by Nor Mazlee, Norazmi, Zul Rasyied, Abdul Rasat, Mazuina, Mohamad, Hadi, Manap

“…These grits might be artificially assumed as crystallites which is common with Gout disease. Based on the medical perspective, crystallites normally inhibit the human joints which may cause intense pain to the human bones or tissues. …”
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Comparative Study of Allopurinol and Uralyt-4 in patients with Hyperuricemia in Diyala Governorate. by Zuhir M. Hussein, Areej A. Hussein, Qutaybaa G. Hussein

“…Conclusion: allopurinol was effective in reducing serum urate in hyperuricemic patients with gout but combination 0f Uralyt-4 (10 mg/d) allopurinol were more efficacious compared with allopurinol (300 mg/d). …”
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Melodías de América: variaciones de lo transnacional en las producciones Calderón by Silvana Flores

“…En este artículo analizaremos un corpus de films mexicanos en donde la música ocupa un rol destacado, que está compuesto por los siguientes títulos: Música, mujeres y amor (Chano Urueta, 1952), Aventura en Río (Alberto Gout, 1953) y Socios para la aventura (Miguel Morayta Martínez, 1958). …”
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Alleviation of Hyperuricemia by Strictinin in AML12 Mouse Hepatocytes Treated with Xanthine and in Mice Treated with Potassium Oxonate by Kuo-Ching Huang, Yu-Ting Chang, Rosita Pranata, Yung-Hsuan Cheng, Yu-Chi Chen, Ping-Chung Kuo, Yi-Hsuan Huang, Jason T. C. Tzen, Rong-Jane Chen

“…Hyperuricemia, an abnormally high level of blood uric acid, is a major risk factor for gout. Although xanthine oxidase inhibitors were clinically used to lower blood uric acid level, the concerned side effects restricted their utilization. …”
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Influence of Long-Term Fasting on Blood Redox Status in Humans by Françoise Wilhelmi de Toledo, Franziska Grundler, Nikolaos Goutzourelas, Fotios Tekos, Eleni Vassi, Robin Mesnage, Demetrios Kouretas

“…We observed that fasting decreased lipid peroxidation (TBARS) and increased total antioxidant capacity (TAC) in plasma, concomitant with a uric acid elevation, known to be associated with fasting and did not cause gout attacks. Reduced glutathione (GSH), glutathione reductase (GR), glutathione peroxidase (GPx) and catalase in erythrocytes did not show significant changes. …”
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Incidence of drug-treated chronic diseases using administrative pharmaceutical data by Shaun Purkiss, Tessa Keegel, Hassan Vally, Dennis Wollersheim

“…Mean percentage differences between PDI estimates varied greatly when compared to survey data (mean 33% (SD ±79%). Diabetes (-29%), gout (4%), glaucoma (69%) and tuberculosis (14%) showed closer associations. …”
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Higher Levels of Serum Uric Acid Have a Significant Association with Lower Incidence of Lower Urinary Tract Symptoms in Healthy Korean Men by Jiwon Hwang, Seungho Ryu, Joong Kyong Ahn

“…Gout has been correlated with the risk of incident benign prostatic hyperplasia. …”
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The genus Porana (Convolvulaceae) - A phytochemical and pharmacological review by Yu Peng, Yu Peng, Ye Li, Yuanyuan Yang, Yuanqing Gao, Hui Ren, Jing Hu, Xiaomin Cui, Wenjing Lu, Hongxun Tao, Zhiyong Chen

“…Pharmacological studies revealed that extracts from this genus and their bioactive components exhibit anti-inflammatory, analgesic, antioxidant, anti-gout, anti-cancer, and anti-diabetic effects. Although this genus is abundant, the development of its pharmacological applications remains limited. …”
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Normal and Pathological NRF2 Signalling in the Central Nervous System by Tony Heurtaux, David S. Bouvier, Alexandre Benani, Sergio Helgueta Romero, Katrin B. M. Frauenknecht, Michel Mittelbronn, Lasse Sinkkonen

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Altered Serum Uric Acid Levels in Kidney Disorders by Gheun-Ho Kim, Jae-Bum Jun

“…Autosomal dominant tubulointerstitial kidney disease (ADTKD) is an important hereditary kidney disease, mainly caused by mutations of uromodulin (UMOD) or mucin-1 (MUC-1). Hyperuricemia and gout are the major clinical manifestations of ADTKD-UMOD and ADTKD-MUC1. …”
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Anti-Hyperuricemic and Xanthine Oxidase Inhibitory Effects of Pogostemon cablin (Blanco) Benth. by Bui Thanh Tung*, Do Thi Hong Khanh, Nguyen Thi Thuy, Trinh Mai Phuong, Nguyen Thi Minh Anh

“…Background and objectives: Hyperuricemia is one of the major causes of gout and other oxidative stress-related diseases. …”
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The pan-liver network theory: From traditional chinese medicine to western medicine by Yaxing Zhang, Xian-Ming Fang

“…The organ interactions centered on the liver not only influence the homeostasis of these indicated organs or tissues, but also contribute to the pathogenesis of cardiometabolic diseases (including obesity, type 2 diabetes mellitus, metabolic [dysfunction]-associated fatty liver diseases, and cardio-cerebrovascular diseases), pulmonary diseases, hyperuricemia and gout, chronic kidney disease, and male and female sexual dysfunction. …”
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Prevalence of Endocrine Disorders Among 6078 Individuals With Down Syndrome in the United States by Anne Rivelli, Veronica Fitzpatrick, Danielle Wales, Laura Chicoine, Gengjie Jia, Andrey Rzhetsky, Brian Chicoine

“…Overall, individuals with DS experienced higher prevalence of adrenal insufficiency and Addison’s disease; thyroid disorders, including hypothyroidism, hyperthyroidism, Hashimoto’s disease, and Graves’ disease; prolactinoma/hyperprolactinemia; diabetes insipidus; type I diabetes mellitus; and gout. Conversely, those with DS had lower prevalence of polycystic ovary syndrome and type II diabetes mellitus. …”
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PENGARUH PEMBERIAN EKTRAK BIJI ANGGUR (Vitis vinifera) TERHADAP KADAR SERUM ASAM URAT PADA TIKUS PUTIH JANTAN (Rattusnorvegicus strain wistar) MODEL HIPERURISEMIA by Novi Puspita Sari, dr Isbandiah, Bambang Widiwanto

“…Hiperurisemia adalah salah satu faktor yang menyebabkan angka kejadian infalmasi gout arthtritis akut, dan beberapa penyakit lain. …”
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The Impact of Musculoskeletal Conditions on Assessed Levels of Care Required by Older Australians by Tiffany K Gill, Steve Wesselingh, Maria C Inacio

“…Introduction Musculoskeletal problems, including conditions such as back pain, neck pain, rheumatoid arthritis, gout and osteoarthritis are common in the population and significant contributors to global disease burden. …”
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