DNA methylation profiles differ in responders versus non-responders to anti-PD-1 immune checkpoint inhibitors in patients with advanced and metastatic head and neck squamous cell c... by Matthias Preusser, Anna Sophie Berghoff, Thorsten Fuereder, Leonhard Müllauer, Gerwin Heller, Angelika Martina Starzer, Katharina Feldmann, Erwin Tomasich, Teresa Hatziioannou, Stefan Traint, Thomas Melchardt, Christoph Minichsdorfer, Ursula Schwarz-Nemec, Maja Nackenhorst

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Comparative effectiveness of multiple different treatment regimens for nonalcoholic fatty liver disease with type 2 diabetes mellitus: a systematic review and Bayesian network meta... by Manjun Deng, Yonghao Wen, JingXin Yan, Yichen Fan, Zhixin Wang, Ruixia Zhang, Li Ren, Yinggui Ba, Haijiu Wang, Qian Lu, Haining Fan

“…Conclusions The high confidence mandates the confident application of these findings as guides for clinical practice. Dapagliflozin and pioglitazone are used for glycaemic control in patients with NAFLD combined with T2DM, and liraglutide is used for weight loss therapy in patients with abdominal obesity. …”
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Early results of transcatheter electrosurgical aortic septotomy for endovascular repair of chronic dissecting aortoiliac aneurysms by Mira T. Tanenbaum, MD, Andres V. Figueroa, MD, K. Benjamin Lee, MD, Jose Eduardo Costa Filho, MD, Marilisa Soto Gonzalez, MD, Mirza S. Baig, MD, Carlos H. Timaran, MD

“…Conclusions: The use of IVUS and fusion-guided TEAS offers a promising technique to facilitate TL expansion and false lumen exclusion in chronic dissecting aortic aneurysms before repair. …”
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In Vitro and In Silico Studies of Neolignans from <i>Magnolia grandiflora</i> L. Seeds against Human Cannabinoids and Opioid Receptors by Pankaj Pandey, Mallika Kumarihamy, Krishna Chaturvedi, Mohamed A. M. Ibrahim, Janet A. Lambert, Murrell Godfrey, Robert J. Doerksen, Ilias Muhammad

“…Radioligand binding assays of <i>n</i>-hexane seeds extract showed displacement of radioligand for cannabinoid (CB1 and CB2) and opioid δ (delta), κ (kappa), and µ (mu) receptors. Bioactivity-guided fractionation afforded 4-<i>O</i>-methylhonokiol (<b>1</b>), magnolol (<b>2</b>), and honokiol (<b>3</b>), which showed higher binding to cannabinoid rather than opioid receptors in radioligand binding assays. …”
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中国城镇居民人均食用植物油消费量的 趋势预测与影响因素分析Trend prediction and influencing factors analysis of per capita edible vegetable oil consumption of urban residents in China... by 严茂林1，葛玮玮 2，张洋2，杨丽1 YAN Maolin 1, GE Weiwei 2, ZHANG Yang 2, YANG Li1

“…Therefore, policy recommendations was proposed, such as guiding the adjustment of oil consumption structure, strengthening quality and safety supervision of edible oil, improving the efficiency of edible oil utilization and eliminating waste.…”
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Landscape Strategies in Architecture by Daniel Jauslin

“…Though this project has not been realised, this thesis makes it possible to describe the building in a guided walk-through. This visualisation of the design as it could have looked if built is also the specific analytical method chosen for this example. …”
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AULOS AND CROTALS IN GRAECO-ROMAN EGYPT by Marwa Elkady

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PUBLICATION ETHICS: GLOBAL ISSUE, REGIONAL CHALLENGES by Behrooz Astaneh, Muhammad Irfan, Sarah Masoumi

“…Publication ethics is an umbrella term encompassing all ethical issues related to scientific publication, ranging from research misconducts such as duplicate publication and guest authorship to research frauds such as data fabrication and plagiarism.1-3 Contrary to the common notion, it is not only the duty of the authors to abide by the guiding principles of publication ethics but responsibility also lies with the authors; editors; reviewers; and publishers, for the appropriate handling of scientific data and should adhere to ethical guidelines of academic research.4 Since ethics is a decision making tool for any course of action and is thus the requirement for human life, it is also a fundamental aspect of research and publication because ignoring it affects the integrity of research, wastes funds and resources, and harms the research community by damaging the reputation of researchers, editors, and institutions.5,6 Moreover, the participants, the general public and the policy makers may be harmed by fraudulent published to address ethical challenges that are faced by the whole research community. 10,19,20 For authors, the organization of courses for improvement in the proficiency in English writing can be useful since the authors from non-English speaking countries often complain of their shortcomings in appropriately phrasing their expression without crossing the boundaries of publication ethics.21 Professional medical writers can also play their role to help such authors but a careful look at the conduct may be required and the internationally made guidelines need to be pragmatically implemented in this region.22-24 For Editors, there can be some solutions to the ethical dilemmas, they face.25 Train the Trainer programs, investing in editors to disseminate the knowledge related to publications and related ethical issues have been useful.26,27 A two year diploma course in Medical Journalism, running in Shiraz University of Medical Sciences is another unique and successful example of promoting awareness of Publication Ethics.28 Another opening for editors to improve their skills in all aspects of their job as an editor including their knowledge and practice of dealing with publication ethics is to create prospects of internship with reputed national and international journals.29,30 All these methods have been successfully used in the past and can be used regularly. …”
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PENGEMBANGAN LEMBAR KERJA PESERTA DIDIK BERWAWASAN AL-QUR’AN DAN BUDAYA MINANGKABAU DALAM PEMBELAJARAN MATEMATIKA KELAS X by Rozi Fitriza, Mezi Szah Putra, Duski Samad

“…The research instruments used were: interview guides with students and educators (at the define and develop stage), concept/task analysis sheets, validation sheets, observation sheets, and student and educator response questionnaires. …”
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Theory and technology of partial backfill non-pillar mining in longwall faces of steeply dipping coal seam by Yongping WU, Jingyu HUANGFU, Hongwei WANG, Bosheng HU, Shenghu LUO

“…It is of great scientific significance for guiding the green, safe, and efficient mining in the steeply dipping coal seam.…”
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A Suicide Prevention Intervention for Emerging Adult Sexual and Gender Minority Groups: Protocol for a Pilot Hybrid Effectiveness Randomized Controlled Trial by Lily A Brown, Jessica L Webster, Jennifer T Tran, James R Wolfe, Jesse Golinkoff, Esha Patel, Amanda C Arcomano, Jennifer Ben Nathan, Alexander Azat O'Connor, Yiqin Zhu, Maria Oquendo, Gregory K Brown, David Mandell, Danielle Mowery, José A Bauermeister

“…EA-SGM groups will be randomized to receive either SPI alone or STARS and will be assessed for 6 months. MethodsGuided by the RE-AIM (reach, efficacy, adoption, implementation, and maintenance) framework, we will recruit and enroll a racially and ethnically diverse sample of 60 EA-SGM individuals reporting past-month suicidal ideation. …”
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Targeted Radiotherapy Using Contact X-ray Brachytherapy 50 kV by Jean-Pierre Gerard, Arthur Sun Myint, Nicolas Barbet, Catherine Dejean, Brice Thamphya, Jocelyn Gal, Lucile Montagne, Te Vuong

“…Targeted radiotherapy aiming at high precision 3D radiotherapy uses stereotactic image-guided external beam radiotherapy machines. To further safely increase the tumor dose, endocavitary brachytherapy (ECB) is an original approach. …”
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Positive effects of low-dose S-ketamine on preventing myocardial injury after thoracoscopic lobectomy in patients aged 70 to 85 by Ziqiang Bi, Lijuan Kong, Jiahui Zhao, Dongdong Song, Fengmei Duan

“…In group S, a low dose of S-ketamine (0.2 mg/kg) was given 1 min before intubation, and the maintenance dose was 0.12 mg·kg−1·h−1. Fluid therapy, guided by cardiac index (CI), changes in stroke volume (△SV), and other dynamic indicators, was used for rehydration during the operation. …”
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The PTSD Family Coach App in Veteran Family Members: Pilot Randomized Controlled Trial by Katherine van Stolk-Cooke, Joseph Wielgosz, Haijing Wu Hallenbeck, Andrew Chang, Craig Rosen, Jason Owen, Eric Kuhn

“…MethodsA total of 200 participants with an average age of 39 (SD 8.44) years, primarily female (193/200, 97%), and White (160/200, 80%) were randomized to self-guided use of either PTSD Family Coach 1.0 (n=104) or a psychoeducation-only app (n=96) for 4 weeks. …”
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Computational Modeling Insights into Extreme Heterogeneity in COVID-19 Nasal Swab Data by Leyi Zhang, Han Cao, Karen Medlin, Jason Pearson, Andreas C. Aristotelous, Alexander Chen, Timothy Wessler, M. Gregory Forest

“…The “virtual population” and the statistical distribution of outcomes over the population are defined by collecting clinically and experimentally guided ranges for the full set of model parameters (1) and (2). …”
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Beliefs of people with salt intake-related heart failure [Crenças de pessoas com insuficiência cardíaca relacionadas à ingesta de sal] [Creencias de las personas con insuficiencia... by Mailson Marques de Sousa, Bernadete de Lourdes André Gouveia, Taciana da Costa Farias Almeida, Maria Eliane Moreira Freire, Simone Helena dos Santos Oliveira

“…Method: this quantitative and qualitative study, guided by the Theory of Planned Behavior, was conducted from January to February 2018, through individual interviews of 26 people with HF in outpatient follow-up in the city of João Pessoa. …”
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Remote Follow-up of Self-isolating Patients With COVID-19 Using a Patient Portal: Protocol for a Mixed Methods Pilot Study (Opal-COVID Study) by David Lessard, Kim Engler, Yuanchao Ma, Adriana Rodriguez Cruz, Serge Vicente, Nadine Kronfli, Sapha Barkati, Marie-Josée Brouillette, Joseph Cox, John Kildea, Tarek Hijal, Marie-Pascale Pomey, Susan J Bartlett, Jamil Asselah, Bertrand Lebouché

“…As for the qualitative analyses, for objective 2 (influences on implementation), semistructured qualitative interviews will be conducted with 4 groups of stakeholders (ie, patient participants, health care professionals, technology developers, and study administrators) and submitted for content analysis, guided by the Consolidated Framework for Implementation Research to help identify barriers to and facilitators of implementation. …”
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Prácticas de Evaluación utilizadas por el Tutor Universitario en el Practicum de la Formación de Maestros by Flor Jiménez, Teresa Mauri

“…The theoretical perspective guiding the study is the sociocultural and situated constructivist perspective. …”
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Authorities of Conduct in Islamic Mysticism and Its Manifestation in Two Paintings of “Dance of Sufis” and “Worldly and Otherworldly Drunkenness” by golnar alibabaei, Khashayar Ghazizadeh

“…These aspects appear in various forms such as vulgarity, greed, and so on, and the seeker, to get rid of their chains and straps, guided by the great teachers and high mystics, relies on the invocations that break him free of the world of evil, and lead him to the kingdom of God. …”
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Significant advancement in geological theories and new discoveries of natural gas in China since the 11th Five-Year Plan by Guoqi Wei, Jian Li, Wei Yang, Zengye Xie, Caiyuan Dong, Yuanqi She, Wei Ma

“…The accumulation theory of ultra-deep reef reservoirs has guided the exploration of Yuanba gas field, the deepest-buried reef gas field in China. …”
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