The Clinical Outcome Evaluation On The Atrial Fibrillation Patients Receiving Warfarin For Secondary Stroke Prevention In The Medication Therapy Adherence Clinic In Serdang And Ser... by Mochamad Djunaedi, Mochamad Djunaedi

“…Patients’ adherence to warfarin therapy as had been guided by Pharmacist was found to be a factor that contributed to the achievement of good quality of anticoagulation control (Odds ratio: 53.3 and 52.0 at p < 0.05 and CI = 95% for those in Serdang and Seremban Hospitals respectively). …”
Get full text

Characterisation of standardised fraction from clinacanthus nutans (SF1) and its anti tumor effects on in vitro and xenograft model by Zainuddin, Nik Aina Syazana Nik

“…Initially, optimization methods of bioassay-guided fractionation was carried out. All collected fractions of C. …”
Get full text

A study of urinary tract infection among housewives in a community setting by Yusoff, Wan Hasnimazmira Wan

“…It is used to help explain how changes and maintenance of health re lated behaviors guides health behavior interventions (Champion & Skinner. 2008). …”
Get full text

Caspase-dependent apoptotic mechanism of gallic acid and its derivatives isolated from quercus infectoria ethyl acetate extract against cervical cancer cells lines (hela) by Ismail, Illyana

“…Gallic acid (GA) and its derivative, methyl gallate (MG), were isolated by using a bioassay-guided isolation technique. The antiproliferative effect that characterised by inhibitory concentration at 50 % cell populations (IC50) of EAQI, GA and MG were determined by using the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] assay at various concentration ranging from 0.39 to 100 μg/ml at 72 hours of treatment in HeLa cell lines and the control serving non-cancerous Vero cell lines. …”
Get full text

Strategizing inclusivity in teaching diverse learners through community of practice in higher education by Awang Hashim, Rosna, Kaur, Amrita, Valdez, Nena P.

“…The research question that guided the study was: What strategies do higher education practitioners devise for their inclusive practices in response to the challenges through a CoP.Methodology - In this study, we adopted a qualitative research paradigm to understand how higher education practitioners perceive diversity and its related challenges in their classrooms and what inclusive strategies do they devise through a CoP. …”
Get full text

Aligning Preprofessional Student Experiences in Integrative Group Medical Visits with Integrative Medicine Core Competencies by Malik K. Tiedt, Bethany M. Kavalakatt, Aisha Chilcoat, Jessica L. Barnhill, Isabel J. Roth

“…Implementation mapping guided efforts to IGMV delivery,11 and the program was found to be feasible and acceptable to patients and providers.12?…”
Get full text

Severe traumatic brain injury: outcome in patients with diffuse brain injury without surgical lesion managed in Hospital Sultanah Aminah, Johor Bahru an observational study by Liew Boon, Seng

“…A total number of 16 patients were treated with ventilation support due to various reasons, which include cerebral resuscitation without ICP-CPP guided management. There were only 15 (20.8%) patients who were treated with standard ICP-CPP guided cerebral resuscitation. …”
Get full text

Etiopathogenesis of chronic kidney disease-associated pruritus: putting the pieces of the puzzle together by Pablo Molina, Raquel Ojeda, Ana Blanco, Guillermo Alcalde, Mario Prieto-Velasco, Nuria Aresté, Juan Manuel Buades, Vicent Esteve Simó, Marian Goicoechea, Rosa Elena Pérez-Morales, Emilio Sánchez-Álvarez, Rafael Sánchez-Villanueva, María Montesa, María Dolores Arenas

“…Other non-uremic causes of pruritus are also discussed, with the aim of guiding the physicians to apply an adequate aetiopathogenic approach to CKD-aP in their day-to-day clinical practice. …”
Get full text

Spatial disparities of ozone pollution in the Sichuan Basin spurred by extreme, hot weather by N. Wang, Y. Du, D. Chen, H. Meng, X. Chen, L. Zhou, G. Shi, Y. Zhan, M. Feng, W. Li, M. Chen, Z. Li, F. Yang

“…This comparison of the difference provides insights into the complex interplay of meteorology, natural emissions, and anthropogenic sources during heatwaves, guiding the necessity of targeted pollution control measures on regional scales.…”
Get full text

Outcomes in Patients with Intact and Resected Brain Metastasis Treated with 5-Fraction Stereotactic Radiosurgery by David J. Carpenter, MD, Andrew T. Fairchild, MD, Justus D. Adamson, PhD, Peter E. Fecci, MD, PhD, John H. Sampson, MD, PhD, James E. Herndon, II, PhD, Jordan A. Torok, MD, Trey C. Mullikin, MD, Grace J. Kim, MD, PhD, Zachary J. Reitman, MD, PhD, John P. Kirkpatrick, MD, PhD, Scott R. Floyd, MD, PhD

“…Linear accelerator-based image-guided HF-SRS consisted of 5 fractions at 5, 5.5, or 6 Gy per fraction. …”
Get full text

Longitudinal MRI-based fusion novel model predicts pathological complete response in breast cancer treated with neoadjuvant chemotherapy: a multicenter, retrospective studyResearch... by YuHong Huang, Teng Zhu, XiaoLing Zhang, Wei Li, XingXing Zheng, MinYi Cheng, Fei Ji, LiuLu Zhang, CiQiu Yang, ZhiYong Wu, GuoLin Ye, Ying Lin, Kun Wang

“…Summary: Background: Accurate identification of pCR to neoadjuvant chemotherapy (NAC) is essential for determining appropriate surgery strategy and guiding resection extent in breast cancer. However, a non-invasive tool to predict pCR accurately is lacking. …”
Get full text

Lymphatic pathway evaluation in congenital heart disease using 3D whole-heart balanced steady state free precession and T2-weighted cardiovascular magnetic resonance by Vasu D. Gooty, Surendranath R. Veeram Reddy, Joshua S. Greer, Zachary Blair, Riad Abou Zahr, Yousef Arar, Daniel A. Castellanos, Sheena Pimplawar, Gerald F. Greil, Jeanne Dillenbeck, Tarique Hussain

“…Together, these sequences can define abnormal lymphatic pathway following single ventricle palliative surgery, thus guiding lymphatic interventional procedures.…”
Get full text

CD4+ T cells are the major predictor of HCMV control in allogeneic stem cell transplant recipients on letermovir prophylaxis by Chris David Lauruschkat, Ihsan Muchsin, Alice Rein, Florian Erhard, Denise Grathwohl, Lars Dölken, Lars Dölken, Carolin Köchel, Christine Susanne Falk, Christine Susanne Falk, Christine Susanne Falk, Hermann Einsele, Sebastian Wurster, Götz Ulrich Grigoleit, Götz Ulrich Grigoleit, Sabrina Kraus

“…Recently, antiviral letermovir prophylaxis during the first 100 days after alloSCT replaced PCR-guided preemptive therapy as the primary standard of care for HCMV reactivations. …”
Get full text

Can Measuring the ‘Dual Anchors of Aorta’ Enhance the Success Rate of TAVR?—A Single-Center Experience by Yang Chen, Md Misbahul Ferdous, Lakshme Kottu, Jie Zhao, Hong-Liang Zhang, Mo-Yang Wang, Guan-Nan Niu, Qing-Rong Liu, Zheng Zhou, Zhen-Yan Zhao, Qian Zhang, De-Jing Feng, Bin Zhang, Zi-Ang Li, Daphne Merkus, Bin Lv, Hai-Yan Xu, Guang-Yuan Song, Yong-Jian Wu

“…Therefore, this study’s primary goal was to provide an initial summary of the medium- and short-term clinical effectiveness of transcatheter aortic valve replacement (TAVR) guided by accurate multi-detector computed tomography (MDCT) measurements in patients with severe and chronic AR, especially in elderly patients. …”
Get full text

Evaluation of Doses to Target Volume and Organs at Risk by Conventional versus RTOG Contouring Based 3D Conformal Plans in Breast Cancer: A Prospective Study by Prabha Verma, Madhup Rastogi, Ajeet Kumar Gandhi, Rohini Khurana, Anoop Kumar Srivastava, Avinav Bharati, Rahat Hadi, Niraj Agarwal

“…Aim: To evaluate the differences in dosimetric parameters to the Organs at Risk (OARs) and target volumes in patients treated with conventional plans vis-à-vis Radiation Therapy Oncology Group contour-guided treatment plans. Materials and Methods: A prospective interventional study was conducted in which 30 patients of histopathologically proven Infiltrating Ductal Carcinoma (IDC) breast, with age range of 18 to 80 years were enrolled. …”
Get full text

Strategies to recruit rural primary care providers to implement a medication for opioid use disorder (MOUD) focused integrated care model by Renee M. Cloutier, Evan S. Cole, Brianna L. McDonough, Daniel A. Lomauro, John P. Miller, Abigail L. Talbert, Todd M. Bear, Nora C. Bridges, Abigail L. Foulds, Rachel Taber, Adam J. Gordon, Gerald T. Cochran, Julie Kmiec, Julie M. Donohue, David Kelley, Ellen DiDomenico, Dale Adair, Janice L. Pringle

“…Once recruited, the Systems Transformation Framework guided planning and implementation activities. Recruitment and implementation activities were assessed with implementation trackers and evaluated by providers via key informant interviews (KIIs). …”
Get full text

Genome-wide association study and haplotype analysis reveal novel candidate genes for resistance to powdery mildew in soybean by Guoqiang Liu, Guoqiang Liu, Yuan Fang, Xueling Liu, Xueling Liu, Jiacan Jiang, Jiacan Jiang, Guangquan Ding, Guangquan Ding, Yongzhen Wang, Yongzhen Wang, Xueqian Zhao, Xueqian Zhao, Xiaomin Xu, Xiaomin Xu, Mengshi Liu, Mengshi Liu, Yingxiang Wang, Yingxiang Wang, Cunyi Yang, Cunyi Yang

“…The candidate genes identified above are all NLR family genes, and these discoveries deepen our understanding of the molecular basis of PMD resistance in soybeans and will be useful for guiding breeding strategies.…”
Get full text

GATEKEEPER’s Strategy for the Multinational Large-Scale Piloting of an eHealth Platform: Tutorial on How to Identify Relevant Settings and Use Cases by Jordi de Batlle, Ivan D Benítez, Anna Moncusí-Moix, Odysseas Androutsos, Rosana Angles Barbastro, Alessio Antonini, Eunate Arana, Maria Fernanda Cabrera-Umpierrez, Gloria Cea, George Ε Dafoulas, Frans Folkvord, Ane Fullaondo, Francesco Giuliani, Hsiao-Ling Huang, Pasquale F Innominato, Przemyslaw Kardas, Vivian W Q Lou, Yannis Manios, Maria Matsangidou, Franco Mercalli, Mounir Mokhtari, Silvio Pagliara, Julia Schellong, Lisa Stieler, Konstantinos Votis, Paula Currás, Maria Teresa Arredondo, Jorge Posada, Sergio Guillén, Leandro Pecchia, Ferran Barbé, Gerard Torres, Giuseppe Fico

“…MethodsThe selection of implementation sites and reference use cases (RUCs) was based on the adoption of a double stratification pyramid reflecting the overall health of target populations and the intensity of proposed interventions; the identification of a principles guiding implementation site selection; and the elaboration of guidelines for RUC selection, ensuring clinical relevance and scientific excellence while covering the whole spectrum of citizen complexities and intervention intensities. …”
Get full text

Identification and validation of a dysregulated TME-related gene signature for predicting prognosis, and immunological properties in bladder cancer by Chong Shen, Chong Shen, Wang Chai, Wang Chai, Jingwen Han, Jingwen Han, Zhe Zhang, Zhe Zhang, Xuejing Liu, Shaobo Yang, Shaobo Yang, Yinlei Wang, Yinlei Wang, Donghuai Wang, Donghuai Wang, Fangxin Wan, Zhenqian Fan, Hailong Hu, Hailong Hu

“…Lastly, we identified SERPINB3 as significantly promoting BC cells migration and invasion through differential expression validation and in vitro phenotypic experiments.ConclusionOur study developed a prognostic model based on nine TMRGs that accurately and stably predicted survival, guiding individual treatment for patients with BC, and providing new therapeutic strategies for the disease.…”
Get full text

Machine-learning-based prediction of the effectiveness of the delivered dose by exhale-gated radiotherapy for locally advanced lung cancer: The additional value of geometric over d... by Nika Guberina, Christoph Pöttgen, Alina Santiago, Sabine Levegrün, Sima Qamhiyeh, Toke Printz Ringbaek, Maja Guberina, Wolfgang Lübcke, Frank Indenkämpen, Martin Stuschke, Martin Stuschke

“…Dosimetric information, especially location and value of Dmin within the CTVi, are vital information for image-guided radiation treatment.…”
Get full text