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BswR controls bacterial motility and biofilm formation in Pseudomonas aeruginosa through modulation of the small RNA RsmZ
Published 2014“…In addition to the contacts between the parallel helices α5 of two monomers, the two helical extensions (α6 and α7) intertwine together to form a homodimer, which is the biological function unit. …”
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Journal Article -
22
The stalks of the motor A1A0 ATP synthase come into the focus : structural insight into subunits E, F and H
Published 2010“…The -helix includes a kink that would bring the two helices of the C-terminus into the coiled-coil arrangement. …”
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Thesis -
23
Stapled BH3 Peptides against MCL-1 : mechanism and design using atomistic simulations
Published 2013“…Affinity is also modulated by the ability of the staples to pre-organize the peptides as helices. Molecular dynamics simulations of these stapled BH3 peptides were carried out followed by determination of the energies of interactions using MM/GBSA methods. …”
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Journal Article -
24
Fabrication and characterization of protein-based tissue scaffold
Published 2011“…And the spectra recorded from the structural analysis indicated the presence of secondary structures (α-helices and β-sheets) in amide I, II, III regions of protein. …”
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Final Year Project (FYP) -
25
Secondary structure predictor
Published 2015“…This means predicting the likelihood of sequences that will form secondary structures such as alpha helices, beta strands and coiled coils. There are two different methods in secondary structure prediction. …”
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Final Year Project (FYP) -
26
Pick one, but be quick : 5' splice sites and the problems of too many choices
Published 2014“…We also discuss recent work demonstrating that U1 snRNA:5′ss helices can accommodate noncanonical registers such as bulged duplexes. …”
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Journal Article -
27
De novo-designed β-sheet heme proteins
Published 2021“…In nature, heme is found to occur predominantly in α-helical structures over β-sheets, which has resulted in significant designs of heme-proteins utilizing coiled coil helices. …”
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Journal Article -
28
Characteristic vibration patterns of odor compounds from bread-baking volatiles upon protein binding : density functional and ONIOM study and principal component analysis
Published 2013“…To gain insight into odorant molecules from bread baking, binding energies and vibration spectra in the gas phase and in the protein environment [7-transmembrane helices (7TMHs) of rhodopsin] were calculated using density functional theory [B3LYP/6-311++G(d,p)] and ONIOM [B3LYP/6-311++G(d,p):PM3] methods. …”
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Journal Article -
29
Assessing the odd secondary structural properties of nuclear small subunit ribosomal RNA sequences (18S) of the twisted-wing parasites (Insecta: Strepsiptera)
Published 2005“…The majority of the base pairings in this structural model map on to the SSU rRNA secondary and tertiary helices that were previously predicted with comparative analysis. …”
Journal article -
30
Structure of a fully assembled γδ T-cell antigen receptor
Published 2024“…The arrangement of CD3 subunits in γδ and αβ TCRs is conserved and, although the transmembrane α-helices of the TCR-γδ and -αβ subunits differ markedly in sequence, the packing of the eight transmembrane-helix bundles is similar<sup>6</sup>. …”
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31
Development of an ultra-stretchable double-network hydrogel for flexible strain sensors
Published 2021“…The hydrogen-bond crosslinked double helices of agar and ionic-coordination interactions of AAC–Fe3+ serve as sacrificial bonds during large deformation to dissipate the energy while the reversible AAC–Fe3+ interactions can be regenerated after stress relief, which greatly increases the toughness of the DN hydrogel. …”
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Journal Article -
32
Structure of the C-terminal domain of the multifunctional ICP27 protein from herpes simplex virus 1
Published 2015“…The structure reveals the C-terminal half of ICP27 to have a novel fold consisting of -helices and long loops, along with a unique CHCC-type of zinc-binding motif. …”
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Journal Article -
33
Design, synthesis and activity studies of antifreeze peptide derived from type I shorthorn sculpin
Published 2015“…All designed peptides show moderate helical content (24-37%) concordant with FTIR results due to the presence of amide I at 1650 – 1658 cm-1 and amide II at 1545 cm-1, which are referred to be the characteristic of α- helices. …”
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Thesis -
34
Understanding Dengue Virus Capsid Protein Interaction with Key Biological Targets
Published 2016“…Interestingly, APOE α-helical N-terminal sequence and structure superimposes with DENV C α-helices α1 and α2. …”
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Journal Article -
35
Phosphatidylinositol 4,5-Bisphosphate Is an HCV NS5A Ligand and Mediates Replication of the Viral Genome
Published 2016“…A similar motif was found to be conserved across all HCV isolates, as well as amphipathic helices of many pathogens and apolipoproteins. Conclusions: PI(4,5)P2 binds to HCV NS5A to promote replication of the viral RNA genome in hepatocytes. …”
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Journal Article -
36
Structural and mechanistic studies of herpes virus proteins
Published 2015“…The structure reveals the C-terminal half of ICP27 to be a bundle of α-helices along with a unique zinc-fingerlike motif. …”
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Thesis -
37
SARS-CoV-2 accessory protein 7b forms homotetramers in detergent
Published 2023“…Addition of p7b to model membranes produced occasional membrane permeabilization, but this was not consistent with bona fide ion channels made of a tetrameric assembly of α-helices.…”
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Journal Article -
38
Skyrmion qubits: challenges for future quantum computing applications
Published 2024“…Magnetic nano-skyrmions develop quantized helicity excitations, and the quantum tunneling between nano-skyrmions possessing distinct helicities is indicative of the quantum nature of these particles. …”
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Journal Article -
39
PC-based software for thermal design of helixchanger heat exchangers
Published 2015“…However, due to its proprietary nature, Shell-and-Tube Heat Exchangers with Helical Baffles also called Helixchanger Heat Exchangers is rarely reported in the open literature. …”
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Final Year Project (FYP) -
40
Expanding heme-protein folding space using designed multi-heme β-sheet mini-proteins
Published 2019“…Nature has primarily exploited helical proteins, over β-sheets, for heme/multi-heme coordination. …”
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Journal Article