Desfecho de pacientes com câncer internados em unidades de terapia intensiva brasileiras com lesão renal aguda Outcomes of cancer patients admitted to Brazilian intensive care unit... by Márcio Soares, Suzana Margarete Ajeje Lobo, André Peretti Torelly, Patricia Veiga de Carvalho Mello, Ulisses Silva, José Mário Meira Teles, Eliézer Silva, Pedro Caruso, Gilberto Friedman, Paulo César Pereira de Souza, Álvaro Réa-Neto, Arthur Oswaldo Vianna, José Raimundo Azevedo, Érico Vale, Leila Rezegue, Michele Godoy, Marcelo Oliveira Maia, Jorge Ibrain Figueira Salluh

“…Kidney injury developed more frequently in patients with hematological malignancies than in patients with solid tumors (26% vs. 11%, P=0.003). …”
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Oxigenação por membrana extracorporal na falência circulatória e respiratória – experiência de um centro by Marisa Passos Silva, Daniel Caeiro, Paula Fernandes, Cláudio Guerreiro, Eduardo Vilela, Marta Ponte, Adelaide Dias, Fernando Alves, Jorge Morais, Andreza Mello, Lino Santos, Paula Castelões, Vasco Gama

“…Access site bleeding and hematologic dysfunction were the most prevalent complication and organ dysfunction, respectively. …”
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Analysis of the efficacy of drilling decompression autologous bone marrow and allogeneic bone grafting in the treatment of HIV-positive patients with early osteonecrosis of the fem... by Shengtao Li, Jie Wang, Rui Ma, Changsong Zhao, Zhengrong Gao, Xuemin Quan, Qiang Zhang

“…General information including ARCO stage, Harris score, VAS score, hematological indexes including CD4+ T lymphocyte count, and HIV viral load was recorded for all patients before surgery. …”
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Efficacy and Safety of Masitinib in Corticosteroid-Dependent Severe Asthma: A Randomized Placebo-Controlled Trial by Davidescu L, Ursol G, Korzh O, Deshmukh V, Kuryk L, Nortje MM, Godlevska O, Devouassoux G, Khodosh E, Israel E, Moussy A, Mansfield CD, Hermine O, Chanez P

“…Yanovsky of National Academy of Medical Sciences of Ukraine, Kyiv, Ukraine; 6Moriana Clinical Research, Brandfort, South Africa; 7Department of Pulmonology, Hôpital de la Croix Rousse, GHN, HCL and Université Claude Bernard Lyon 1, Lyon, France; 8Department of Pulmonology, Municipal Nonprofit Enterprise, City Clinical Hospital #13, Kharkiv, Ukraine; 9Harvard Medical School, Boston, MA, USA; 10Division of Pulmonary and Critical Care Medicine and Allergy and Immunology, Brigham and Women’s Hospital, Boston, MA, USA; 11AB Science, Paris, France; 12Imagine Institute, INSERM UMR 1163 and CNRS ERL 8254, Laboratory of Cellular and Molecular Mechanisms of Hematological Disorders and Therapeutic Implication, Hôpital Necker, Paris, France; 13Université Paris Descartes, Sorbonne Paris Cité, Paris, France; 14Clinique des Bronches, Allergie et Sommeil, APHM Hôpital Nord, C2VN Center INSERM INRAE UMR1062, Aix-Marseille Université, Marseille, FranceCorrespondence: Pascal Chanez, Clinique des Bronches, Allergie et Sommeil, APHM Hôpital Nord, C2VN Center INSERM INRAE UMR1062, Aix-Marseille Université, Marseille, France, Tel +33 6 50 71 07 05, Email Pascal.CHANEZ@univ-amu.frBackground: Masitinib is an oral tyrosine kinase inhibitor that selectively targets mast cell activity and platelet-derived growth factor receptor (PDGFR) signaling, both of which are implicated in various mechanisms of asthma pathogenesis.Objective: Assessment of masitinib as an add-on to standard maintenance therapy as compared with placebo in the treatment of oral corticosteroid-dependent severe asthma.Methods: We conducted a randomized (2:1), placebo-controlled study of masitinib (6 mg/kg/d) in adults with severe asthma uncontrolled by high dose inhaled corticosteroids and long-acting beta-adrenoreceptor agonists plus oral corticosteroids (OCS) (≥ 7.5 mg/d). …”
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Comparison of clinicopathological features and treatment outcomes in aggressive primary intestinal B- and T/NK-cell lymphomas by Wei-Li Ma, Kun-Huei Yeh, Ming Yao, Jih-Luh Tang, Chung-Wu Lin, Yu-Ting Wang, Yi-Chun Yeh, Hsiu-Po Wang, Ann-Lii Cheng, Sung-Hsin Kuo

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COMPARATIVE CHARACTERISTICS OF QUALITY OF LIFE INDICATORS IN PATIENTS WITH CHRONIC HEART FAILURE WITH REDUCED LEFT VENTRICULAR EJECTION FRACTION DEPENDING ON IRON DEFICIENCY TYPE by V. P. Іvanov, M. O. Kolesnyk

“…In addition, a number of significant relations between QoL indicators according to MLHFQ, PH and MH scale SF-36 and hematological parameters and a number of iron metabolism indicators were detected during the study. …”
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Acompanhamento farmacoterapêutico dos pacientes com leucemia mieloide crônica em uso de mesilato de imatinibe na Universidade Federal do Ceará The pharmacotherapeutic follow- up of... by Sterfen S. Aquino, Romélia P. Gonçalves, Lilianne B. Silva

“…The cases in the chronic phase had previous intolerance to interferon alpha (IFN- α). Complete hematological responses were observed in 7 patients: 5 in the chronic phase, 1 in the accelerated phase and 1 in blast crisis. …”
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Noninvasive predictors of cardiac arrhythmias in bodybuilders by Kadir Uğur Mert, Serdar İlgüy, Gurbet Özge Mert, Muhammet Dural, Kemal Iskenderov

“…A detailed cardiovascular and systemic examination was performed at the beginning of the study to collect demographic data and anthropometric measures. Biochemical and hematologic, echocardiographic, 24-h Holter, and ECG measurements were obtained from all participants. …”
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Human seminal plasma stimulates the migration of CD11c+ mononuclear phagocytes to the apical side of the colonic epithelium without altering the junctional complexes in an ex vivo... by Marco Baratella, Valeria Iannone, Mariangela Cavarelli, Chiara Foglieni, Paola Viganò, Christiane Moog, Ugo Elmore, Ugo Elmore, Silvia Nozza, Massimo Alfano, Andrea Salonia, Andrea Salonia, Stefania Dispinseri, Gabriella Scarlatti

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Should ascitis volume and anthropometric measurements be estimated in hospitalized alcoholic cirrotics? ¿Es conveniente estimar el volumen ascítico y las medidas antropométricas en... by E. M. Silva, L. C. S. L. Moráis, J. E. M. Medeiros Filho, L. S. R. Asciutti, H. A. C. Rocha, M.ª J. C. Costa, M.ª C. R. Gonçalves, J. Faintuch

“…Measurements included ultrasonographically estimated ascitis volume, dry body mass index/BMI , upper arm anthropometrics, hematologic counts and liver function tests. Results: Population (age 48.3 ± 11.3 years, BMI 21.1± 3.5 kg/m², serum albumin 2.5 ± 0.8 g/dL) was mostly in the Child-Pugh C category (77.8%) but clinically stable. …”
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Genetic Study of SARS-CoV-2 Non Structural Protein 12 in COVID-19 Patients Non Responders to Remdesivir by Marta Santos Bravo, Rodrigo Alonso, Dafne Soria, Sonsoles Sánchez Palomino, Ángela Sanzo Machuca, Cristina Rodríguez, José Alcamí, Francisco Díez-Fuertes, Àlvar Simarro Redon, Juan Carlos Hurtado, Francesc Fernández Avilés, Marta Bodro, Elisa Rubio, Jose Luis Villanueva, Andrea Vergara, Pedro Castro, Montserrat Tuset, Genoveva Cuesta, Pedro Puerta, Carolina García, María del Mar Mosquera Gutiérrez, Miguel J. Martínez, Jordi Vila, Alex Soriano, María Ángeles Marcos

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Púrpura trombocitopênica imunológica como manifestação inicial de lúpus eritematoso sistêmico juvenil Idiopathic thrombocytopenic purpura as initial manifestation of juvenile syste... by Josefina Aparecida Pellegrini Braga, Mary Hokazono, Maria Teresa R. A. Terreri, Maria Odete E. Hilário

“…The Systemic Lupus Erythematosus classification criteria were (in decreasing frequency): malar erythema and positivity of ANA in 5 patients; arthritis, hematological (thrombocytopenia) and immunological alterations (positivity of anti-DNA) in 4 patients; photosensitivity and positivity of anti-cardiolipin in 3 patients. …”
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The role of the IRS1 gene (rs2943640) in the comorbid course of type 2 diabetes mellitus, obesity and arterial hypertension by I. Vivsiana, H. Habor, M. Marushchak

“…Exclusion criteria from the study: signs of clinically significant neurological, mental, renal, hepatic, immune, gastrointestinal, urogenital disorder; injuries of the musculoskeletal system, skin, sense organs, endocrine system (except T2DM); or uncontrolled hematologic diseases; acute pancreatitis, unstable or life-threatening heart disease; patients with malignant neoplasms who have not been in complete remission for at least 5 years, medication (drug) dependence, and alcohol dependence. …”
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Spray-dried plasma in the recovery of light piglets at weaning: production performance, blood profile, diarrhea frequency and economic viability<br>Plasma sanguíneo desidratado na... by Débora Barbosa Braz, Álvaro Henrique de Sousa Altmann, Marina Avena Tarsitano, Roberta Abrami Monteiro da Silva, Eduardo Raele de Oliveira, David Fernandes Gavioli, Ana Maria Bridi, Caio Abércio da Silva, Danyel Bueno Dalto, Renata Katsuko Takayama Kobayashi, Emerson José Venâncio

“…The aim of this research was to evaluate the effects of spray-dried plasma (SDP) on the performance, hematological profile, diarrhea frequency and economic viability of this ingredient in diets for light piglets at weaning, with 21 days of age. …”
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Perinatal effects of basuco consumption during pregnancy Repercusión perinatal del consumo de basuco durante la gestación by Olga Atehortua, Luz E. Gómez, Amanda Mejía, Carlos Benavides, Fanny Cuesta González, José E. Caicedo R., Rafael J. Manotas Cabarcas, Ofelia Miranda

“…Despite significantly higher blood-lead levels in the exposed mothers and infants no evidence could be found of liver, kidney or hematological alterations; lead-poisoning signs were absent. …”
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Analysis of mortality metrics associated with a comprehensive range of disorders in Denmark, 2000 to 2018: A population-based cohort study by Oleguer Plana-Ripoll, Julie W. Dreier, Natalie C. Momen, Anders Prior, Nanna Weye, Preben Bo Mortensen, Carsten B. Pedersen, Kim Moesgaard Iburg, Maria Klitgaard Christensen, Thomas Munk Laursen, Esben Agerbo, Marianne G. Pedersen, Jørgen Brandt, Lise Marie Frohn, Camilla Geels, Jesper H. Christensen, John J. McGrath

“…We focus on 39 general medical conditions to simplify the presentation of results, which cover 10 broad categories: circulatory, endocrine, pulmonary, gastrointestinal, urogenital, musculoskeletal, hematologic, mental, and neurologic conditions and cancer. …”
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Rare antibody-associated hemolytic transfusion reaction and transfusion-related acute lung injury: a case report by Tim N. Beck, Natalee G. Young, Michelle L. Erickson, Ignacio Prats

“…Hemorrhage is one of the most common surgical complications and the risk of bleeding is particularly acute in patients with hematologic deficiencies. Management of surgical bleeding can be divided into two phases. …”
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Experiência clínica inicial na desmineralização química da valva aórtica: potencial aplicação como procedimento minimamente invasivo Chemical demineralization of the aortic valve:... by Ricardo Carvalho Lima, Gerhard Wimmer-Greinecker, Mário Gesteira Costa, Mozart Augusto Soares de Escobar, Roberto Diniz, Antônio Césio, Frederico Vasconcelos, Alexandre Menezes, Robert Poser, Jerry Riebman

“…Likewise, no neurologic, systemic, metabolic or hematologic events were seen. The postoperative transvalvular gradient identified by echocardiography showed an improvement in the systolic gradient and in the mean gradient. …”
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Intervención nutricional en niños y adolescentes con fibrosis quística: Relación con la función pulmonar Nutritional intervention in children and adolescents with cystic fibrosis:... by C. Martínez-Costa, A. Escribano, F. Núñez Gómez, L. García-Maset, J. Luján, L. Martínez-Rodríguez

“…Concurrently, respiratory secretions culture and spiro-metry were obtained; and annually, biochemistry, hematologic and feces determinations. Nutritional intervention included: dietary recommendations, oral or invasive enteral nutrition (EN) and pharmacologic treatment with pancreatic enzymes, fat-soluble vitamins, minerals and oligoelements. …”
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Body Mass Index as a Major Prognostic Contributing Factor in COVID-19: A Multicentral Egyptian Study by Mohammed HAEM, Hassan MH, Abdalla H, Mahmoud MA, Maher A, Malak M, Tag-Adeen M, Izzaldin MR, Adel S, Ali WE, Abo-Rahma A, Abd Elnabi MGM, Abdalla IAM, Morsy MFM, Sayed MAFM, Abdelaal UM

“…Adult respiratory distress syndrome (ARDS), cardiac, neurological, and hematological complications, and incidence of myalgia and bed sores were most frequent among obese and overweight patients. …”
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