Available methods to enhance regenerative potential of plastic materials for bone defects replacement in orthopedics. Part 3. Use of autologous human red bone marrow by A. M. Fain, A. Yu. Vaza, S. F. Gnetetskiy, K. I. Skuratovskaya, V. B. Bondarev, Yu. A. Bogolyubskiy, R. S. Titov, A. Yu. Sergeev

“…The results of treatment for delayed consolidation of bone fractures are also described. Hematopoietic stem cells give rise to all cellular components of the circulating blood, such as red blood cells, lymphocytes, neutrophils, and platelets. …”
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New insights of growth hormone (GH) actions from tissue-specific GH receptor knockouts in mice by Edward O. List, Darlene E. Berryman, Elizabeth A. Jensen, Prateek Kulkarni, Savannah McKenna, John J. Kopchick

“…Targeted tissues include liver, muscle, fat, brain, bone, heart, intestine, macrophage, pancreatic beta cells, hematopoietic stem cells, and multi-tissue “global”. In this review, we provide a brief history and description of the 21 tissue-specific GHR knockout mouse lines. …”
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Lymphoid Genes Expression in Mouse Embryonic Stem Cells with Differentiation on Feeder Free Condition by Majid Mossahebimohammadi, Saeid Kaviani, Mina Soufizomorrod, Masoud Soleimani, Saeid Abroun, Gholamreza Khamisipour, Najmaldin Saki

“…Lymphocytes generated from hematopoietic stem cells. We designed a feeder free culture condition to generate lymphoid lineage cells from ESCs. …”
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A Case of Chronic Myeloid Leukemia Presenting with Osteoid Osteoma: A Diagnostic Dilemma by Mannavi Suman, Anis Bandyopadhyay, Arnab Kumar Ghosh, Sk Rahamatulla, Alakananda Choudhury

“…Chronic myeloid leukemia is a hematological malignancy resulting from a clonal proliferation of hematopoietic stem cells of the myeloid series. It is developed by chromosomal translocation. …”
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A quiet space during rush hour: Quiescence in primordial germ cells by Nathalie Oulhen, Gary Wessel

“…Quiescent stem cells are found in many adult human tissues, the hematopoietic stem cells are paradigmatic, and more recently it appears that stem cell of the germ line in many animals display quiescence characters. …”
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Gene Transcription as a Therapeutic Target in Leukemia by Alvina I. Khamidullina, Ekaterina A. Varlamova, Nour Alhuda Hammoud, Margarita A. Yastrebova, Alexandra V. Bruter

“…Blood malignancies often arise from undifferentiated hematopoietic stem cells or partially differentiated stem-like cells. …”
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The molecular basis of α-thalassemia: a model for understanding human molecular genetics. by Higgs, D, Gibbons, R

“…In particular the authors describe how the α genes are normally switched on during erythropoiesis and switched off as hematopoietic stem cells commit to nonerythroid lineages. In addition, the principles by which α-globin expression may be perturbed by natural mutations that cause α-thalassemia are reviewed.…”

Can mobilization of bone marrow stem cells be an alternative regenerative therapy to stem cell injection in a rat model of chronic kidney disease? by Shereen Morsy, Mona F. Mansour, Mohamed Abdo, Yasser El‐Wazir

“…Granulocyte colony‐stimulating factor (G‐CSF) is known to mobilize hematopoietic stem cells from bone marrow to the peripheral circulation. …”
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Bicistronic CAR-T cells targeting CD123 and CLL1 for AML to reduce the risk of antigen escape by Danni Xie, Xin Jin, Rui Sun, Meng Zhang, Wenyi Lu, Xinping Cao, Ruiting Guo, Yi Zhang, Mingfeng Zhao

“…CD123 and CLL1 are expressed in most AML blasts and leukemia stem cells, and their low expression in normal hematopoietic stem cells makes them ideal targets for CAR-T. …”
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Modeling of genetic regulatory networks in the differentiation of neural crest stem cells to sensory neurons by means of boolean networks by Jorge Marcelo Aráus Patiño, Helena Groot Restrepo, Andrés Fernando González Barrios

“…Surprisingly, these motifs take place in similar stages during the development of erythrocytes from hematopoietic stem cells. Regarding the complexity of the GRN found, we then used Random Boolean Networks (RBN) for this purpose, which showed key components as well as the dynamics of the process through changes in initial conditions. …”
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Existence and asymptotics of traveling wave fronts for a coupled nonlocal diffusion and difference system with delay by Abdennasser Chekroun

“…In this paper, we consider a general study of a recent proposed hematopoietic stem cells model. This model is a combination of nonlocal diffusion equation and difference equation with delay. …”
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The Mesenchymal Stem Cells From The Veterinary Sciences Perspective by Nancy B. Riaño G., Victor J. Vera A., Luis Carlos Villamil J.

“…The source of the somatic stem cells is the bone marrow, in which the hematopoietic stem cells and the mesenchymals (MSCs) are found. …”
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Distinct origins of adult and embryonic blood in Xenopus. by Ciau-Uitz, A, Walmsley, M, Patient, R

“…The first adult hematopoietic stem cells (HSCs) are thought to form in association with the floor of the dorsal aorta, and we have detected such aortic clusters in Xenopus using hematopoietic markers. …”

Humanized mouse models for organ-specific autoimmune diseases. by Friese, M, Jensen, LT, Willcox, N, Fugger, L

“…The latest development - humanizing most of the immune system by transplanting human hematopoietic stem cells into severely immunodeficient mice - should lead to even better modeling.…”

Clonal Hematopoiesis of Indeterminate Potential: New Insights from Recent Studies by Adrian Schmidt

“…Clonal hematopoiesis of indeterminate potential (CHIP) is a condition characterized by accumulation of one or several somatic mutations in hematopoietic stem cells in the bone marrow. Recent studies have provided new data on the prevalence of CHIP mutations, which are relatively common in both cancer patients and the general population, and especially in older adults. …”
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Modeling of genetic regulatory networks in the differentiation of neural crest stem cells to sensory neurons by means of boolean networks by Jorge Marcelo Aráus Patiño, Helena Groot Restrepo, Andrés Fernando González Barrios

“…Surprisingly, these motifs take place in similar stages during the development of erythrocytes from hematopoietic stem cells. Regarding the complexity of the GRN found, we then used Random Boolean Networks (RBN) for this purpose, which showed key components as well as the dynamics of the process through changes in initial conditions. …”
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Sex differences in normal and malignant hematopoiesis by Xiaojing Cui, Xinghui Zhao, Ying Liang

“…Hematopoiesis is a continuous and well-regulated process requiring both the capacity for self-renewal and the potential for differentiation of hematopoietic stem cells. Multiple studies indicate that sex hormones exert significant effects on not only hematopoietic stem and progenitor cells, but also the development of hematopoietic lineages, resulting in sexual dimorphisms in normal hematopoiesis. …”
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Epitranscriptomics in Normal and Malignant Hematopoiesis by Crescenzio Francesco Minervini, Elisa Parciante, Luciana Impera, Luisa Anelli, Antonella Zagaria, Giorgina Specchia, Pellegrino Musto, Francesco Albano

“…In physiological conditions, hematopoiesis is a tightly regulated process that produces differentiated blood cells starting from hematopoietic stem cells. Alteration of this process can occur at different levels in the pathway that leads from the genetic information to the phenotypic manifestation producing malignant hematopoiesis. …”
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Single-Cell Approaches to Deconvolute the Development of HSCs by Yang Xiang, Ryohichi Sugimura

“…Hematopoietic stem cells (HSCs) play a core role in blood development. …”
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Designing Lentiviral Vectors for Gene Therapy of Genetic Diseases by Valentina Poletti, Fulvio Mavilio

“…Examples are hematopoietic stem cells used in gene therapy for hematological or neurometabolic diseases or T cells for immunotherapy of cancer. …”
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