Endolyn (CD164) modulates the CXCL12-mediated migration of umbilical cord blood CD133+ cells. by Forde, S, Tye, B, Newey, S, Roubelakis, M, Smythe, J, McGuckin, C, Pettengell, R, Watt, S

“…Hematopoietic stem cell/hematopoietic progenitor cell (HSC/HPC) homing to specific microenvironmental niches involves interactions between multiple receptor ligand pairs. …”

Dissecting BMP signaling input into the gene regulatory networks driving specification of the blood stem cell lineage by Kirmizitas, A, Meiklejohn, S, Ciau-Uitz, A, Stephenson, R, Patient, R

“…Hematopoietic stem cells (HSCs) that sustain lifelong blood production are created during embryogenesis. …”

The in Vitro Assessment of Biochemical Factors in Hepatocyte like Cells Derived from Umbilical Cord Blood Stem Cells by A KHoramroodi, S Nasri, I Amiri

“…Introduction & Objective: Umbilical cord blood (UCB) is a source of Hematopoietic Stem Cells (HSC) and progenitor cells that can reconstitute the hematopoietic system in patients with malignant and nonmalignant disorders. …”
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The features of experimental allergic encephalomyelitis after stem cells transplantation by Leonid D. Pichkur, Vira M. Semenova, Svitlana A. Verbovska, Natalia P. Oleksenko, Samuel T. Akinola

“…To study the course of experimental allergic encephalomyelitis (EAE) after intravenous administration of hematopoietic stem cells (HSC) and suboccipital transplantation of fetal neurocells (FNC), and treatment impact on intensity of neural tissue renewing in rats with EAE.Materials and methods. …”
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Relation between FMS-like tyrosine kinase 3 factor and hematological parameter in acute lymphoblastic leukemia patients by flow cytometry by Zainab Samir Al-Ali, Bassam Mohammed

“…The main expression of FLT3 on bone marrow (BM) cells especially CD34+ hematopoietic stem cells, early progenitor cells, dendritic progenitor cells, and other cells of organs (brain, placenta, and testis). …”
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KINOME EXPRESSION PROFILING FOR RISK STRATIFICATION OF MYELODYSPLASTIC SYNDROMES by C.-Y. Yao, C.-C. Lin, Y.-H. Wang, C.-J. Kao, C.-H. Tsai, H.-A. Hou, H.-F. Tien, C.-L. Hsu, W.-C. Chou

“…Introduction: Myelodysplastic syndrome (MDS) is a heterogeneous constellation of myeloid neoplasms originating from the clonal proliferation of aberrant hematopoietic stem cells (HSC). The human kinome, which comprises over five hundred kinases, plays a critical role in regulating numerous cellular functions. …”
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The humanized DRAGA mouse (HLA-A2. HLA-DR4. RAG1 KO. IL-2R g c KO. NOD) establishes inducible and transmissible models for influenza type A infections by Mirian Mendoza, Devi Gunasekera, Kathleen P. Pratt, Qi Qiu, Sofia Casares, Teodor-D. Brumeanu

“…NOD) in which the murine immune system has been replaced by a long-term, functional HIS via infusion of CD34+ hematopoietic stem cells (HSC) from cord blood. Herein, we report that the DRAGA mice can sustain inducible and transmissible H1N1 and H3N2 influenza A viral (IAV) infections. …”
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Bioinformatic Description of Immunotherapy Targets for Pediatric T-Cell Leukemia and the Impact of Normal Gene Sets Used for Comparison by Rimas J Orentas, Jessica eNordlund, Jianbin eHe, Sivasish eSindiri, Crystal eMackall, Terry J Fry, Javed eKhan

“…To find new targets for T-ALL immunotherapy, we employed a bioinformatic comparison to broad normal tissue arrays, hematopoietic stem cells (HSC), and mature lymphocytes, then filtered the results for transcripts encoding plasma membrane proteins. …”
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PD-1/PD-L1 Checkpoints and Resveratrol: A Controversial New Way for a Therapeutic Strategy by Dominique Delmas, François Hermetet, Virginie Aires

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A study of the correlation between the serum Latexin levels and the mTORC subunits Raptor and Rictor in the molecular pathogenesis of chronic lymphocytic leukemia by Gokhan Pektas, Volkan Karakus, Deniz Cetin, Tuba Dogan Edgunlu

“…Hematopoietic stem cells (HSCs) ensure the lifelong production of blood cells throughout a lifetime. …”
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Two-Pore Channels Regulate Inter-Organellar Ca²⁺ Homeostasis in Immune Cells by Philip Steiner, Elisabeth Arlt, Ingrid Boekhoff, Thomas Gudermann, Susanna Zierler

“…Here, we focus on the function of these unique ion channels in mast cells, which are leukocytes that mature from myeloid hematopoietic stem cells. The cytoplasm of these innate immune cells contains a large number of granules that comprise messenger substances, such as histamine and heparin. …”
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Cellular and Molecular Mechanisms of Environmental Pollutants on Hematopoiesis by Pablo Scharf, Milena Fronza Broering, Gustavo Henrique Oliveira da Rocha, Sandra Helena Poliselli Farsky

“…It is orchestrated mostly by hematopoietic progenitor cells (hematopoietic stem cells (HSCs)) that are capable of self-renewal and differentiation. …”
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Alpha fetoprotein (AFP) participates in the build up of hematopoietic cells in the early embryonic stage: an abortion case observation by Jianhong An, Yufeng Zhang, Jiao Luo, Hong Shen

“…The cells in the center of the blood islands further develop into primitive blood cells, such as hematopoietic stem cells. The blood island in the yolk sac further develops into the extramedullary hematopoietic tissue in 1 week at the 3rd to 4th week. …”
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Loss of Pcgf5 Affects Global H2A Monoubiquitination but Not the Function of Hematopoietic Stem and Progenitor Cells. by Sha Si, Yaeko Nakajima-Takagi, Kazumasa Aoyama, Motohiko Oshima, Atsunori Saraya, Hiroki Sugishita, Manabu Nakayama, Tomoyuki Ishikura, Haruhiko Koseki, Atsushi Iwama

“…Pcgf5 is expressed preferentially in hematopoietic stem cells (HSCs) and multipotent progenitors (MPPs) compared with committed myeloid progenitors and differentiated cells. …”
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M6A-BERT-Stacking: A Tissue-Specific Predictor for Identifying RNA N6-Methyladenosine Sites Based on BERT and Stacking Strategy by Qianyue Li, Xin Cheng, Chen Song, Taigang Liu

“…As the most abundant RNA methylation modification, N6-methyladenosine (m6A) could regulate asymmetric and symmetric division of hematopoietic stem cells and play an important role in various diseases. …”
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Complement dependent TNFα production in neutrophil-like HL60 cells by Hiroyuki Tabata, Hiroyuki Morita, Kenichi Kouyama, Yumi Tohyama

“…Neutrophils develop in the bone marrow (BM) from hematopoietic stem cells (HSCs) through a series of progenitor cells and mature neutrophils play a critical role in the human immune system. …”
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Scaling Pharmacodynamics from Rats to Humans to Support Erythropoietin and Romiplostim Combination Therapy to Treat Erythropoietin-Resistant Anemia by Xiaoqing Fan, Wojciech Krzyzanski, Dongyang Liu, Raymond S. M. Wong, Xiaoyu Yan

“…We further found that the combination of EPO with romiplostim, a thrombopoietin receptor agonist that can stimulate the expansion of hematopoietic stem cells, can treat EPO-resistance. In this study, we performed interspecies pharmacodynamic (PD) scaling of this combination therapy for human dose prediction. …”
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Evaluation of CD96 and CD123 in CD34+ leukemic stem cells in acute myeloid leukemia patients and their relation to response to induction therapy by Haidar H Al-Fatlawi, Raad Jaber Musa

“…Background: Leukemic stem cells (LSCs) are thought to originate either from normal hematopoietic stem cells or from more differentiated progenitor cells. …”
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The Role of Cell and Gene Therapies in the Treatment of Infertility in Patients with Thyroid Autoimmunity by Sanja Medenica, Dzihan Abazovic, Aleksandar Ljubić, Jovana Vukovic, Aleksa Begovic, Gaspare Cucinella, Simona Zaami, Giuseppe Gullo

“…Mesenchymal Stem Cells (MSCs) represent a heterogeneous fraction of self-renewal, multipotent non-hematopoietic stem cells that display profound immunomodulatory and immunosuppressive features and promising therapeutic effects. …”
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Jagged-1 Signaling in the Bone Marrow Microenvironment Promotes Endothelial Progenitor Cell Expansion and Commitment of CD133+ Human Cord Blood Cells for Postnatal Vasculogenesis. by Mika Ishige-Wada, Sang-Mo Kwon, Masamichi Eguchi, Katsuto Hozumi, Hideki Iwaguro, Taro Matsumoto, Noboru Fukuda, Hideo Mugishima, Haruchika Masuda, Takayuki Asahara

“…To investigate the close relationship between hematopoietic stem cells and human endothelial progenitor cells (EPCs) in the bone marrow niche, we examined the effects of Notch signals [Jagged-1 and Delta-like ligand (Dll)-1] on the proliferation and differentiation of human CD133+ cell-derived EPCs. …”
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