Synthesis of M-Ag₃PO₄, (M = Se, Ag, Ta) Nanoparticles and Their Antibacterial and Cytotoxicity Study by Faiza Qureshi, Muhammad Nawaz, Mohammad Azam Ansari, Firdos Alam Khan, Mahmoud M. Berekaa, Samar A. Abubshait, Rayyanah Al-Mutairi, Alok K. Paul, Veeranoot Nissapatorn, Maria de Lourdes Pereira, Polrat Wilairatana

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Bufei Jianpi Formula Improves Mitochondrial Function and Suppresses Mitophagy in Skeletal Muscle via the Adenosine Monophosphate-Activated Protein Kinase Pathway in Chronic Obstruc... by Jing Mao, Jing Mao, Ya Li, Ya Li, Ya Li, Suxiang Feng, Suxiang Feng, Suxiang Feng, Xuefang Liu, Xuefang Liu, Yange Tian, Yange Tian, Qingqing Bian, Qingqing Bian, Qingqing Bian, Junzi Li, Junzi Li, Yuanyuan Hu, Yuanyuan Hu, Lanxi Zhang, Lanxi Zhang, Huige Ji, Huige Ji, Suyun Li, Suyun Li, Suyun Li

“…Bufei Jianpi formula (BJF), a traditional Chinese herbal formulation, has been shown to improve skeletal muscle tension and tolerance via inhibition of cellular apoptosis in COPD rat models. …”
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Integration of ion-mobility high-resolution liquid chromatography/mass spectrometry-based untargeted metabolomics and desorption electrospray ionization-mass spectrometry imaging t... by Yadan Zou, Mengxiang Ding, Huimin Wang, Humin Xie, Meiting Jiang, Yuying Zhao, Xiaoyan Xu, Ying Hu, Xiumei Gao, Hongda Wang, Wenzhi Yang

“…Conclusively, the established strategy is practical to unveil the holistic ginsenosides variation of ginseng induced by the processing, which is useful in the quality control of both the herbal medicines and foods.…”
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KDM3A and KDM4C Regulate Mesenchymal Stromal Cell Senescence and Bone Aging via Condensin-mediated Heterochromatin Reorganization by Biao Huang, Bin Wang, Wayne Yuk-Wai Lee, Kin Pong U, Kam Tong Leung, Xican Li, Zhenqing Liu, Rui Chen, Jia cheng Lin, Lai Ling Tsang, Baohua Liu, Ye chun Ruan, Hsiao Chang Chan, Gang Li, Xiaohua Jiang

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Research trends in the field of the gut-brain interaction: Functional dyspepsia in the spotlight – An integrated bibliometric and science mapping approach by Tai Zhang, Tai Zhang, Tai Zhang, Beihua Zhang, Beihua Zhang, Beihua Zhang, Xiangxue Ma, Xiangxue Ma, Xiangxue Ma, Jiaqi Zhang, Jiaqi Zhang, Jiaqi Zhang, Yuchen Wei, Yuchen Wei, Yuchen Wei, Fengyun Wang, Fengyun Wang, Fengyun Wang, Xudong Tang

“…Six thematic clusters emerged (Helicobacter pylori infection; pathophysiological mechanisms of FD; extraintestinal co-morbidities and overlap syndromes associated with FD; herbal medicine in FD; diabetic gastroparesis; and dietary factors in FD). …”
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An exploratory, open-label, randomized, multicenter trial of hachimijiogan for mild Alzheimer’s disease by Mosaburo Kainuma, Shinji Ouma, Shinobu Kawakatsu, Osamu Iritani, Ken-Ichiro Yamashita, Tomoyuki Ohara, Shigeki Hirano, Shiro Suda, Tadanori Hamano, Sotaro Hieda, Masaaki Yasui, Aoi Yoshiiwa, Seiji Shiota, Masaya Hironishi, Kenji Wada-Isoe, Daiki Sasabayashi, Sho Yamasaki, Masayuki Murata, Kouta Funakoshi, Kouji Hayashi, Norimichi Shirafuji, Hirohito Sasaki, Yoshinori Kajimoto, Yukiko Mori, Michio Suzuki, Hidefumi Ito, Kenjiro Ono, Kenjiro Ono, Yoshio Tsuboi

“…Novel treatments for mild AD are of utmost importance.Objective: To assess the effectiveness of hachimijiogan (HJG), a traditional Japanese herbal medicine (Kampo), in the treatment of mild AD.Methods: This exploratory, open-label, randomized, multicenter trial enrolled patients with mild AD whose score on the Mini Mental State Examination (MMSE) was over 21points. …”
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Therapeutic prospects of ceRNAs in COVID-19 by Lin Liu, Lin Liu, Lin Liu, Yao Zhang, Yao Zhang, Yao Zhang, Yu Chen, Yu Chen, Yu Chen, Yueshui Zhao, Yueshui Zhao, Yueshui Zhao, Jing Shen, Jing Shen, Jing Shen, Xu Wu, Xu Wu, Xu Wu, Mingxing Li, Mingxing Li, Mingxing Li, Meijuan Chen, Xiaobing Li, Yuhong Sun, Li Gu, Wanping Li, Fang Wang, Lei Yao, Zhuo Zhang, Zhangang Xiao, Zhangang Xiao, Zhangang Xiao, Zhangang Xiao, Fukuan Du, Fukuan Du, Fukuan Du

“…Currently, immunotherapy, cell therapy, antiviral therapy, and Chinese herbal medicine have been applied in the clinical treatment of the new coronavirus; however, more efficient and safe drugs to control the progress of the new coronavirus are needed. …”
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Therapeutic potential of the mitochondria-targeted antioxidant MitoQ in mitochondrial-ROS induced sensorineural hearing loss caused by Idh2 deficiency by Ye-Ri Kim, Jeong-In Baek, Sung Hwan Kim, Min-A Kim, Byeonghyeon Lee, Nari Ryu, Kyung-Hee Kim, Deok-Gyun Choi, Hye-Min Kim, Michael P. Murphy, Greg Macpherson, Yeon-Sik Choo, Jinwoong Bok, Kyu-Yup Lee, Jeen-Woo Park, Un-Kyung Kim

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Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3-β pathway by Zhifu Cui, Ningning Jin, Felix Kwame Amevor, Gang Shu, Xiaxia Du, Xincheng Kang, Zifan Ning, Xun Deng, Yaofu Tian, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang, Xiaoqi Wang, Xue Han, Jing Feng, Xiaoling Zhao

“…Salidroside (SDS) is an herbal drug which has shown numerous pharmacological activities, such as protecting mitochondrial function, attenuating cell apoptosis and inflammation, and promoting antioxidant defense system. …”
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Hepatotoxic metabolites in Polygoni Multiflori Radix— Comparative toxicology in mice by Shixiao Wang, Shixiao Wang, Xiang Kong, Xiang Kong, Ning Chen, Ning Chen, Pengwei Hu, Pengwei Hu, Hamza Boucetta, Hamza Boucetta, Zhaoliang Hu, Zhaoliang Hu, Xin Xu, Xin Xu, Pei Zhang, Pei Zhang, Xiang Zhan, Xiang Zhan, Ming Chang, Ming Chang, Rui Cheng, Rui Cheng, Wei Wu, Wei Wu, Min Song, Min Song, Yuting Lu, Yuting Lu, Taijun Hang, Taijun Hang

“…Nine groups of mice with 28 days of oral administration of these herbal extracts or 2,3,5,4′-tetrahydroxystilbene-2-O-β-D-glucoside (TSG, major and unique characteristic component in PM)-herb combinations were set as follows: Group-1, control; Group-2, PM ethanol-extract (PME); Group-3, PM praeparata ethanol-extract (PMPE); Group-4, Rhubarb ethanol-extract (RME); Group-5, Steamed rhubarb ethanol-extract (RMPE); Group-6, TSG; Group-7, PMPE-TSG combination; Group-8, RME-TSG combination; Group-9, RMPE-TSG combination. …”
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A national survey on how to improve traditional Chinese medicine learning internationally: Perceptions from both teachers and students by Yuhang Zhu, Yan Wu, Hao Zhang, Yanfei Zhao, Yule Ren, Wei Hu, Pan Li, Huiyi Wang, Ying Wang, Boda Zhang, Yujie Wang, Hongwen Yuan, Jiping Zhang, Wenqiang Li, Yufang Zhao, Jie Zhao, Yedong Shi, Yanye Shu, Xiao Zhang, Yan Sun, Sheng Yu, Ling Yang, Zhenbo Geng, Jiali Chen, Kun Lv, Weilin Wang, Wenjuan Xue, Yinger Gu, Fangfang Wang, Xiangrong Xu, Fan Qu

“…The top three interesting contents were acupuncture (75.5%), Chinese herbal medicine (63.8%), and massage (55.0%). Conclusion: To improve TCM learning among international undergraduates majoring in conventional medicine, integration of Chinese culture into TCM course, comparison of traditional medicine in different countries with TCM, application of the teaching method with case reports, and emphasization of clinical practice as well as modern research on TCM should be fully considered.…”
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Anti-allergic Hydroxy Fatty Acids from Typhonium blumei Explored through ChemGPS-NP by Michal Korinek, Michal Korinek, Yi-Hong Tsai, Mohamed El-Shazly, Mohamed El-Shazly, Kuei-Hung Lai, Kuei-Hung Lai, Anders Backlund, Shou-Fang Wu, Shou-Fang Wu, Wan-Chun Lai, Tung-Ying Wu, Shu-Li Chen, Yang-Chang Wu, Yang-Chang Wu, Yang-Chang Wu, Yuan-Bin Cheng, Yuan-Bin Cheng, Yuan-Bin Cheng, Tsong-Long Hwang, Tsong-Long Hwang, Tsong-Long Hwang, Bing-Hung Chen, Bing-Hung Chen, Bing-Hung Chen, Fang-Rong Chang, Fang-Rong Chang, Fang-Rong Chang, Fang-Rong Chang, Fang-Rong Chang

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Antidepressants for smoking cessation. by Hughes, JR, Stead, L, Hartmann-Boyce, J, Cahill, K, Lancaster, T

“…Significant effects were also not detected for monoamine oxidase inhibitors (RR 1.29, 95% CI 0.93 to 1.79, N = 827; 1 trial moclobemide, 5 selegiline), the atypical antidepressant venlafaxine (1 trial, N = 147, RR 1.22, 95% CI 0.64 to 2.32), the herbal therapy St John's wort (hypericum) (2 trials, N = 261, RR 0.81, 95% CI 0.26 to 2.53), or the dietary supplement SAMe (1 trial, N = 120, RR 0.70, 95% CI 0.24 to 2.07). …”

Antioxidant and flavonoid activities in different varieties of Ficus deltoidea jack (Mas Cotek) leaves by Mansor, Mohd Hakiman

“…Hence, the general objective of this study was to evaluate the antioxidant activity and flavonoid contents of three F. deltoidea varieties that are commonly used as herbal medicines in Malaysia. Specific objectives were to determine the total antioxidant capacity in leaf extracts of F. deltoidea using different solvent extractions, to analyse and identify the flavonoid content in leaf extracts of F. deltoidea, and to examine the flavonoid production in cell suspension culture of F. deltoidea. …”
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Predictive factors and clinical efficacy of Chinese medicine Shengji ointment in the treatment of diabetic foot ulcers in the elderly: a prospective study by Yang Zhao, Yang Zhao, Yang Zhao, Zheng-Hong Li, Song Sheng, Xin-Yue Dai, Qing-Na Li, Wei-Yi Cao, Rui Gao, Rui Gao, Rui Gao, Xing-Fang Liu, Hong-Yang Gao

“…The combined treatment of Chinese herbal Shengji ointment and bromelain positively influenced granulation tissue development. …”
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Effect of co-trimoxazole prophylaxis on morbidity and mortality of HIV-exposed, HIV-uninfected infants in South Africa: a randomised controlled, non-inferiority trial by Brodie Daniels, PhD, Anna Coutsoudis, ProfPhD, Eshia Moodley-Govender, PhD, Helen Mulol, PhD, Elizabeth Spooner, MBBCh, Photini Kiepiela, PhD, Shabashini Reddy, MSc, Linda Zako, MBChB, Nhan T Ho, PhD, Louise Kuhn, ProfPhD, Gita Ramjee, PhD

“…Infants were included in the study if they were breastfeeding at the screening and enrolment visits, and their mother was planning to breastfeed for at least 6 months; were a singleton birth and had a birthweight of 2 kg or more; had no clinically observed genetic disorders; and had no serious illnesses and had not received antibiotics or traditional medications (such as herbal remedies). Infants were randomly assigned (1:1) to receive co-trimoxazole or no co-trimoxazole. …”
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Retrospective Analysis of Experimental and Clinical Studies of Flakozid in Viral Hepatitis by V. V. Karabaeva, L. V. Krepkova, A. N. Babenko, V. V. Bortnikova, T. V. Fateeva, P. G. Mizina, N. S. Mikheeva, O. N. Karabaeva

“…Viral hepatitis (HV) by its socio-economic significance occupies one of the leading places in human infectious pathology, therefore, the development of fundamentally new methods of prevention, diagnosis and treatment, as well as the creation of new antiviral drugs remain relevant. An antiviral herbal drug "Flakozid" has been created in VILAR, which is presented in a dosage form – 0,1 g tablets for oral administration.Аim. …”
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Deciphering the active constituents of Dabushen decoction of ameliorating osteoarthritis via PPARγ preservation by targeting DNMT1 by Lu Qiu, Lu Qiu, Min Zhang, Min Zhang, Chenghao Li, Chenghao Li, Yehu Hou, Yehu Hou, Hao Liu, Hao Liu, Jia Lin, Jia Lin, Juan Yao, Juan Yao, Dong Zhu Duan, Yi Xi Zhang, Yi Xi Zhang, Mi Li, Mi Li, Ya Ling Li, Ya Ling Li, Peng Wang, Jin Tian Li, Xiao Jie Jin, Xiao Jie Jin, Xiao Jie Jin, Yong Qi Liu, Yong Qi Liu

“…In conclusion, this study elucidates that the active constituents of DD (alisol A, emodin, taxifolin, isoliquiritigenin, and schisandrin C) could ameliorate osteoarthritis via PPARγ preservation by targeting DNMT1.These findings facilitated clinical use of DD and provided a valuable strategy for developing natural epigenetic modulators from Chinese herbal formula.…”
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2,3,5,4′-Tetrahydroxystilbene-2-O-β-D-Glucoside improves female ovarian aging by Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Hung-Yun Lin, Yung-Ning Yang, Yung-Ning Yang, Yi-Fong Chen, Tung-Yung Huang, Dana R. Crawford, Hui-Yu Chuang, Hui-Yu Chuang, Yu-Tang Chin, Hung-Ru Chu, Hung-Ru Chu, Zi-Lin Li, Zi-Lin Li, Ya-Jung Shih, Ya-Jung Shih, Yi-Ru Chen, Yi-Ru Chen, Yu-Chen S. H. Yang, Yih Ho, Paul J. Davis, Paul J. Davis, Jacqueline Whang-Peng, Jacqueline Whang-Peng, Kuan Wang

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Chinese Law on Foods and Medicines by Anu Lähteenmäki-Uutela

“…In 2006, it was agreed for example that member states should support clinical studies of herbal medicines30, and seek efficient sanctions for false drug advertising, particularly internet advertising31. …”
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