Showing 1 - 20 results of 67 for search '"hereditary diffuse gastric cancer"', query time: 0.28s Refine Results
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    EARLY DIAGNOSTICS AND TOTAL GASTRECTOMY OF HEREDITARY DIFFUSE GASTRIC CANCER by L. N. Lyubchenko, M. G. Filippova, O. A. Anurova, P. B. Nazliev, I. S. Stilidi, M. M. Davydov

    Published 2017-12-01
    “…The case report describes a rare case of hereditary diffuse gastric cancer, associated with a CDH1 gene mutation and reported in the Russian population for the fist time. …”
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    Article
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    HEREDITARY DIFFUSE GASTRIC CANCER: GENETIC ASPECTS AND PROPHYLACTIC TOTAL GASTRECTOMY by L. N. Lyubchenko, M. G. Filippova, O. A. Anurova, P. B. Nazliev, I. S. Stilidi

    Published 2018-09-01
    “…The case report describes a rare case of hereditary diffuse gastric cancer (HDGC)  associated with CDH1 gene mutation, which is reported in the Russian population for the first  time. …”
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    Article
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    Hereditary diffuse gastric cancer therapeutic roadmap: current and novel approaches in a nutshell by Fadi E. El Rami, Hampartsoum B. Barsoumian, Gebran W. Khneizer

    Published 2020-10-01
    “…Hereditary diffuse gastric cancer (HDGC) is a rare malignancy characterized by autosomal dominant inheritance of pathological variants of the CDH1 gene encoding E-cadherin, which is involved in cell–cell adhesion, maintenance of epithelial architecture, tumor suppression, and regulation of intracellular signaling pathways. …”
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    Article
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    New Variants in the CDH1 Gene in Iranian Families with Hereditary Diffuse Gastric Cancer by Majid Kheirollahi, Maryam Saneipour, Mohammad Amin Tabatabaiefar, Mehrdad Zeinalian, Mohammad Minakari, Abbas Moridnia

    Published 2020-10-01
    “…<strong>Background:</strong> Hereditary diffuse gastric cancer (HDGC) is a hereditable form of diffuse gastric cancer with very aggressive tumors, poor prognosis, and delayed clinical signs. …”
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    Article
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    Hereditary Diffuse Gastric Cancer: A Comparative Cohort Study According to Pathogenic Variant Status by Tim Marwitz, Robert Hüneburg, Isabel Spier, Jan-Frederic Lau, Glen Kristiansen, Philipp Lingohr, Jörg C. Kalff, Stefan Aretz, Jacob Nattermann, Christian P. Strassburg

    Published 2020-12-01
    “…Hereditary diffuse gastric cancer (HDGC) is an inherited cancer susceptibility syndrome characterized by an elevated risk for diffuse gastric cancer (DGC) and lobular breast cancer (LBC). …”
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    Article
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    Attitudes toward preimplantation genetic testing and quality of life among individuals with hereditary diffuse gastric cancer syndrome by Ibrahim H. Shah, Erin E. Salo-Mullen, Kimberly A. Amoroso, David Kelsen, Zsofia K. Stadler, Jada G. Hamilton

    Published 2022-09-01
    “…Abstract Background Hereditary Diffuse Gastric Cancer (HDGC) syndrome is an autosomal dominant hereditary cancer predisposition associated with germline pathogenic/likely pathogenic variants in the CDH1 gene. …”
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    Article
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    CDH1 Gene and Hereditary Diffuse Gastric Cancer Syndrome: Molecular and Histological Alterations and Implications for Diagnosis And Treatment by Wenyi Luo, Faysal Fedda, Patrick Lynch, Dongfeng Tan

    Published 2018-12-01
    “…Mutations of CDH1, the gene encoding E-cadherin, are the most common germline mutations detected in gastric cancer and underlie hereditary diffuse gastric cancer (HDGC) syndrome. All reported HDGCs are the pure diffuse type by Lauren classification and are associated with dismal prognosis once the tumor invades the submucosa. …”
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    Article
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    The psychosocial impact of undergoing prophylactic total gastrectomy (PTG) to manage the risk of Hereditary Diffuse Gastric Cancer (HDGC) by Hallowell, N, Lawton, J, Badger, S, Richardson, S, Hardwick, R, Caldas, C, Fitzgerald, R

    Published 2016
    “…Individuals identified as at high risk of developing Hereditary Diffuse Gastric Cancer (HDGC) are advised to undergo prophylactic surgery - have their stomach removed - in their early twenties. …”
    Journal article