Infection frequency of hepatitis C virus and IL28B haplotypes in Papua New Guinea, Fiji, and Kiribati by Harrison, G, Pryor, J, Malani, J, Supuri, M, Masta, A, Teriboriki, B, Toatu, T, Penny, D, Allain, J, Barnes, E, Pybus, O, Klenerman, P

“…WHO and the US Centres for Disease Control and Prevention report the prevalence of HCV in the South Pacific islands (countries within the WHO-WPR) to be high (5–10% and >2% respectively). However, since HCV is not tested for in many of these countries, there is sparse data available to support this assertion. …”

Influence of vocal and aerodynamics aspects on the voice-related quality of life of older adults by Larissa Thaís Donalonso SIQUEIRA, Kelly Cristina Alves SILVERIO, Giédre BERRETIN-FÉLIX, Kátia Flores GENARO, Ana Paula FUKUSHIRO, Alcione Ghedini BRASOLOTTO

“…Results older adults tend to present high V-RQOL scores. Among women, roughness, APQ, and HNR parameters were negatively correlated with V-RQOL, whereas F 0 was positively. …”
Get full text

The Response of the Human Umbilical Vein Endothelial Cell Transcriptome to Variation in Magnesium Concentration by Lujain A. Almousa, Andrew M. Salter, Marcos Castellanos, Sean T. May, Simon C. Langley-Evans

“…Whole genome transcription analysis was used to explore the acute (24 h) effects of magnesium on human umbilical vascular endothelial cells (HUVEC) cultured in low (0.1 mM) or high (5 mM) concentrations. With low magnesium 2728 transcripts were differentially expressed compared to the 1 mM control cultures and 3030 were differentially expressed with high magnesium. 615 transcripts were differentially expressed under both conditions, of which only 34 showed a concentration-dependent response. …”
Get full text

Characterization of pancreatic cancer with ultra-low tumor mutational burden by Taisuke Imamura, Ryo Ashida, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Katsuhisa Ohgi, Mihoko Yamada, Shimpei Otsuka, Keiichi Hatakeyama, Takeshi Nagashima, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi

“…The TMB was classified as High (≥ 5.0), Low (< 5.0, ≥ 1.0), or Ultra-low (< 1.0). …”
Get full text

Latency Trend Analysis as a Guide to Screening Malignancy Survivors for Second Primary Thyroid Cancer by Mohammad Hussein, Lauren Mueller, Peter P. Issa, Muhib Haidari, Lily Trinh, Eman Toraih, Emad Kandil

“…A latency trend analysis identified persistent high risk for development of SPTC after diagnosis of lymphoma, leukemia, soft tissue tumors, kidney, breast, and uterine cancer; elevated 10-year risk for most cancers such as salivary gland, melanoma, stomach, lung, colon, ovarian, pancreas, prostate, and bladder; and high 5-year risk after cancers such as larynx, oral, orbit, bone, small intestine, and liver. …”
Get full text

Controlling Nutritional Status (CONUT) Score as a Potential Prognostic Indicator of In-Hospital Mortality, Sepsis and Length of Stay in an Internal Medicine Department by Nicoletta Miano, Maurizio Di Marco, Salvatore Alaimo, Giuseppe Coppolino, Giuseppe L’Episcopo, Stefano Leggio, Roberto Scicali, Salvatore Piro, Francesco Purrello, Antonino Di Pino

“…This is a retrospective study analyzing data from 369 patients, divided into four groups based on the CONUT score: normal (0–1), mild–high (2–4), moderate–high (5–8), and marked high (9–12). In-hospital all-cause mortality increased from normal to marked high CONUT score group (2.2% vs. 3.6% vs. 13.4% vs. 15.3%, <i>p</i> < 0.009). …”
Get full text

The 30-year cardiovascular risk trajectories and their independently associated factors in participants of a Brazilian cohort (CUME Study) by Renata Soares Passinho, Josefina Bressan, Helen Hermana Miranda Hermsdorff, Fernando Luiz Pereira de Oliveira, Adriano Marçal Pimenta

“…Three CVR trajectories were identified: Low-Low (68.3%), Medium-Medium (26.2%), and High-High (5.5%). Male sex, living in a stable union, and having moderate and high intakes of ultra-processed foods were positively associated with the Medium-Medium and High-High CVR trajectories. …”
Get full text

The “Habitat Provision” Index for Assessing Floodplain Biodiversity and Restoration Potential as an Ecosystem Service—Method and Application by Christine Fischer, Christine Fischer, Christian Damm, Francis Foeckler, Marion Gelhaus, Lars Gerstner, Rebecca M. B. Harris, Rebecca M. B. Harris, Tim G. Hoffmann, Janette Iwanowski, Hans Kasperidus, Dietmar Mehl, Simone A. Podschun, Andrea Rumm, Barbara Stammel, Mathias Scholz

“…The index uses a five-step value to describe the importance of a floodplain area for typical species and habitats from “very high” (=5) to “very low” (=1). The aim of this “habitat provision index” is to provide a tool for planners and decision makers to compare and analyze the effects of past or future measures. …”
Get full text

Risk factors for major adverse cardiovascular events after the first acute coronary syndrome by Marjo Okkonen, Aki S. Havulinna, Olavi Ukkola, Heikki Huikuri, Arto Pietilä, Heli Koukkunen, Seppo Lehto, Juha Mustonen, Matti Ketonen, Juhani Airaksinen, Y. Antero Kesäniemi, Veikko Salomaa

“…Risk factor analyses showed that 23% of ACS survivors continued smoking and cholesterol levels were still high (>5mmol/l) in 24% although 86% of the patients were taking lipid lowering medication.Conclusion Diabetes, higher Charlson index and HF are the most important risk factors of MACE after the first ACS. …”
Get full text

Organic Hazes as a Source of Life’s Building Blocks to Warm Little Ponds on the Hadean Earth by Ben K. D. Pearce, Sarah M. Hörst, Joshua A. Sebree, Chao He

“…In this work, we produce organic hazes in the lab in atmospheres with high (5%) and low (0.5%) CH _4 abundances and analyze the solid particles for nucleobases, amino acids, and a few other organics using GC/MS/MS to obtain their concentrations. …”
Get full text

Synthesis and In Vitro Biological Evaluation of <i>p</i>-Carborane-Based Di-<i>tert</i>-butylphenol Analogs by Sebastian Braun, Sanja Jelača, Markus Laube, Sven George, Bettina Hofmann, Peter Lönnecke, Dieter Steinhilber, Jens Pietzsch, Sanja Mijatović, Danijela Maksimović-Ivanić, Evamarie Hey-Hawkins

“…The incorporation of <i>p</i>-carborane and further substitution of the <i>p</i>-position resulted in four carborane-based di-<i>tert</i>-butylphenol analogs that showed no or weak COX inhibition but high 5-LO inhibitory activities in vitro. Cell viability studies on five human cancer cell lines revealed that the <i>p</i>-carborane analogs <b>R-830-Cb</b>, <b>S-2474-Cb</b>, <b>KME-4-Cb</b>, and <b>E-5110-Cb</b> exhibited lower anticancer activity compared to the related di-<i>tert</i>-butylphenols. …”
Get full text

Melt-casted Li1.5Al0.3Mg0.1Ge1.6(PO4)3 glass ceramic electrolytes: A comparative study on the effect of different oxide doping by Sofia Saffirio, Hamideh Darjazi, Marco Etzi Coller Pascuzzi, Federico Smeacetto, Claudio Gerbaldi

“…A remarkable anodic oxidation stability up to 4.8 V vs Li+/Li is assessed by LAMGP-B system, which accounts for promising prospects for its use in combination with high-energy (high-V) cathodes.…”
Get full text

Design Space Approach for the Optimization of Green Fluidized Bed Granulation Process in the Granulation of a Poorly Water-Soluble Fenofibrate Using Design of Experiment by Mohamed H. Fayed, Ahmed Alalaiwe, Ziyad S. Almalki, Doaa A. Helal

“…It was found that X₁ and X₂ at high (5.69% <i>w</i>/<i>w</i>) and low (2 g/min) levels, respectively, demonstrated the optimum operating conditions. …”
Get full text

Reactivity of Basaltic Minerals for CO₂ Sequestration via In Situ Mineralization: A Review by Muhammad Hammad Rasool, Maqsood Ahmad

“…Based on this analysis, an <i>M.H. reactivity scale</i> was introduced, which establishes a relationship between the reactivity of dominant and reactive minerals in basalt and their potential for carbonation, ranging from low (1) to high (5). The study will help in choosing the most suitable type of basalt for the most promising CO₂ sequestration based on the percentage of reactive minerals. …”
Get full text

A study to compare ramosetron and ondansetron for prevention of post-operative nausea and vomiting in patients undergoing laparoscopic cholecystectomy under general anesthesia by Amit Dahiya, Rashmi, Vasudha Govil, Suraj Garg, Ruchika Singhmar, Radhika Malik

“…Background: The incidence of nausea and vomiting following laparoscopic cholecystectomy is very high. 5-hydroxytryptamine receptor antagonists are drug of choice for prevention of post-operative nausea and vomiting (PONV) because of their good efficacy and very few side effects in comparison to other antiemetics. …”
Get full text

Synthesis of Novel Triphenylamine-Based Organic Dyes with Dual Anchors for Efficient Dye-Sensitized Solar Cells by Samar E. Mahmoud, Ahmed A. Fadda, Ehab Abdel-Latif, Mohamed R. Elmorsy

“…The extinction coefficients of the organic dyes SM1-5 are high (5.36–9.54 104 M−1 cm−1), indicating a high aptitude for light harvesting. …”
Get full text

The quality of non-prescription medicine counselling in Finnish pharmacies – a simulated patient study by Niina Alastalo, Piia Siitonen, Johanna Jyrkkä, Katri Hämeen-Anttila

“…The quality of counselling was defined as poor (1–2 points), moderate (3–4 points), or high (5–6 points) based on developed scenario-based scoring criteria. …”
Get full text

Oxygenated right ventricular assist device as part of veno-venopulmonary extracorporeal membrane oxygenation to support the right ventricle and pulmonary vasculature by Asad Ali Usman, Marisa Cevasco, Marc O. Maybauer, Audrey Elizabeth Spelde, Salim Olia, Christian Bermudez, Michael Ibrahim, Wilson Szeto, William J. Vernick, Jacob T. Gutsche

“…Concurrently, due to infection, tachycardia, and refractory hypoxemia, high V-V ECMO flows to match high cardiac output are often necessary to maintain systemic oxygenation. …”
Get full text

Association between emotional intelligence and academic performance among students in Gandaki Medical College, Pokhara by Rami Shrestha, Nirmala Shrestha, Sapana Koju, Ratna Keshari Tako

“…Results: The mean level of emotional intelligence was high (5.055±0.798) among Nepalese medical students. …”
Get full text

HPV-related oropharyngeal cancer early detection in gay and bisexual men is an “orphan” practice: A qualitative analysis among healthcare providers by I. Niles Zoschke, Sarah L. Bennis, J. Michael Wilkerson, Cynthia L. Stull, Alan G. Nyitray, Alan G. Nyitray, Samir S. Khariwala, C. Mark Nichols, B. R. Simon Rosser, Charlene Flash, Charlene Flash, Charlene Flash, Michael W. Ross

“…If detected early, human papillomavirus (HPV)-16-associated oropharyngeal cancer has a high 5-year survival rate. Risk factors such as high numbers of oral sex partners, disparities in smoking and drinking, and low rates of HPV vaccination may put gay and bisexual men at even higher risk for oropharyngeal cancer.MethodsWe recruited 21 healthcare providers in Minneapolis-St. …”
Get full text