Correlation between sperm DNA methylation level and semen quality among 73 college students in Chongqing, China by WANG Lihong, WANG Lihong, HE Shijun, CHEN Qing, LING Xi, SUN Lei

“…Meanwhile, there were no significant differences in the percentages of different grade of sperm (grade A~D) in the high 5mC group than the low 5mC group (P>0.05). Conclusion Elevated sperm DNA methylation level may be a biomarker for the decrease of sperm density and total sperm count, while is not correlated with indicators of sperm chromatin integrity. …”
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Structural, Electronic and Magnetic Properties of Mn₂Co_1-xV_xZ (Z = Ga, Al) Heusler Alloys: An Insight from DFT Study by Fatima Abuova, Talgat Inerbaev, Aisulu Abuova, Nurpeis Merali, Nurgul Soltanbek, Gulbanu Kaptagay, Marina Seredina, Vladimir Khovaylo

“…It was found that the XA structure is more stable at low V concentrations, while the <i>L</i>2₁ structure is energetically favorable at high V concentrations. A transition from <i>L</i>2₁ to XA ordering occurs near x = 0.5, which qualitatively agrees with the experimental results. …”
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Thoracoscore: Predicting risk of in-hospital mortality for patients undergoing pulmonary resection by Đurić Dejan, Mališanović Gorica, Gvozdenović Ljiljana

“…Thoracoscore was divided into 4 risk groups: low (0–3), moderate (3.1–5), high (5.1–8) and very high (> 8). The correlation between observed and expected mortality was 0.99, by category of risk. …”
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Definitive locoregional therapy (LRT) versus bridging LRT and liver transplantation with wait-and-not-treat approach for very early stage hepatocellular carcinoma by Peiman Habibollahi, Stephen Hunt, Therese Bitterman, Terence P. Gade, Michael C. Soulen, Gregory Nadolski

“…Survival rate at the end of 5 years was significantly better for the wait-and-not-treat group (P = 0.013).CONCLUSION:Based on the findings of current retrospective study, treating veHCC (UNOS T1 stage) patients listed for LT with bridging LRT after disease progression to T2 stage appears to be safe and effective with high 5-year survival rates.…”
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CLINICAL AND GENETIC CHARACTERISTICS OF MUCOLIPIDOSIS II AND IIIA TYPES IN CHILDREN by A. N. Semyachkina, E. Yu. Voskoboeva, Т. M. Bukina, A. M. Bukina, E. A. Nikolaeva, I. S. Dantsev, M. N. Kharabadze, Yu. I. Davydova

“…The clinical diagnosis was confirmed by the results of laboratory methods of investigation: normal parameters of renal excretion of glycosiminoglycans (GAG), high (5-15 times higher than normal) activity of lysosomal hydrolases in blood plasma and detection of mutations in the GNPTAB gene.35 probands are completely genotyped. …”
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4316 Preoperative Goal-setting by Patients is Correlated with Baseline and Not 6-week Outcomes following Total Knee Arthroplasty (TKA) by Vesta Nwankwo, Janet Bettger, Cindy L. Green, Thomas Risoli

“…Patients were categorized by pre-surgical (baseline) goal rating: low = 0-2, intermediate = 3-4, and high = 5-10. Outcomes including gait speed and the KOOS were assessed within 10 days prior to surgery and 6-weeks post-surgery. …”
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Discontinuation of government subsidized HIV pre‐exposure prophylaxis in Australia: a whole‐of‐population analysis of dispensing records by Nicholas Andrew Medland, Doug Fraser, Benjamin R. Bavinton, Fengyi Jin, Andrew E. Grulich, Heath Paynter, Rebecca Guy, Hamish McManus

“…Large variations were observed, particularly according to prescriber characteristics: discontinuation was higher among people prescribed PrEP by low caseload (≤10 patients) prescribers (61.2%) than by high caseload (>100 patients) prescribers (31.1%, p<0.001), and by prescribers practising in areas with low estimated prevalence (<1.0%) of gay men (64.1%) than high (>5%) prevalence (36.7%, p<0.001). Women and younger people were more likely to discontinue, while patients receiving a higher level of government subsidy were less likely. …”
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Digestive tolerability and acceptability of Fibersol-2 in healthy and diarrheal children 1–3 years old at a rural facility, Bangladesh: Results from a four arm exploratory study by Abu Sadat Mohammad Sayeem Bin Shahid, Shahnawaz Ahmed, Tanzina Tazul Renesa, Anindita Tasnim Onni, Sampa Dash, Yuka Kishimoto, Sumiko Kanahori, Tahmeed Ahmed, Abu Syed Golam Faruque, Mohammod Jobayer Chisti

“…Two presumptive doses, low (2.5g) and high (5g), twice daily with 50 ml drinking water for seven days were the interventions. …”
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Assessment of cardiovascular risk factors among HIV-infected patients aged 50 years and older in Cameroon by Henri Olivier Tatsilong Pambou, Amandine Gagneux-Brunon, Bertrand Tatsinkou Fossi, Frederic Roche, Jessica Guyot, Elisabeth Botelho-Nevers, Caroline Dupre, Bienvenu Bongue, Celine Nguefeu Nkenfou

“…The 10-year CVD risk score was calculated using two tools: the validated Framingham risk score (FRS) (low < 10%, moderate 10–20% and high ≥ 20%) and SCORE score (SSC) (low < 3%, moderate 3–4% and high ≥ 5%). Multiple logistic regression models were constructed to examine the respective relationships between the binary dependent variable high CVD risk (FRS ≥ 20%) and the population group, alcohol consumption (more than 10 glasses of beer per week, or more than 35.7 cl/day) and hypertriglyceridemia (independent variables). …”
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Assessment of Tumour Budding in Colorectal Carcinoma and its Correlation with Pathological Staging among Patients undergoing Resection at a Tertiary Care Hospital in Kerala, India by Neha Mohan, KV Kalaranjini, Limi Mohandas

“…Tumour budding was categorised as low (0-1 bud), intermediate (2-4 buds), or high (5 or more buds). Immunohistochemistry (IHC) analysis with Pancytokeratin was carried out when assessment with H&E slides alone was difficult. …”
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Predictors of Toxicity in a Randomized Study of Consolidation Chemoradiation Versus Observation After First Line Chemotherapy in Advanced Gall Bladder Cancers by Sushma Agrawal, MD, Anshika Gupta, MD, Vishwas Kapoor, PhD, Rahul Rahul, MCH, Ashish Singh, MCH, Prabhakar Mishra, PhD, Rajan Saxena, MS

“…Duodenum V45 >45% (P = .02) predicted grade 3 anemia. Numerically high V15 duodenum (98%, P = .11), large PTV2 volume >484 cc (P = .06) and prior stenting had predilection for gastrointestinal bleed. …”
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Combining prognostic nutritional index (PNI) and controlling nutritional status (CONUT) score as a valuable prognostic factor for overall survival in patients with stage I–III colo... by Harin Kim, Dong-Min Shin, Jae-Hoon Lee, Eun-Suk Cho, Hye Sun Lee, Su-Jin Shin, Eun Jung Park, Seung Hyuk Baik, Kang Young Lee, Jeonghyun Kang

“…The controlling nutritional status scores were classified as low (0–1), intermediate (2–4), and high (5–12) scores. The cut-off values for prognostic nutritional index and inflammatory markers were calculated using the X-tile program. …”
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Radiation-induced lung injury after breast cancer treatment: incidence in the CANTO-RT cohort and associated clinical and dosimetric risk factors by Anna Gueiderikh, Thomas Sarrade, Youlia Kirova, Youlia Kirova, Brigitte De La Lande, Florent De Vathaire, Florent De Vathaire, Florent De Vathaire, Guillaume Auzac, Anne Laure Martin, Sibille Everhard, Nicolas Meillan, Nicolas Meillan, Nicolas Meillan, Celine Bourgier, Celine Bourgier, Celine Bourgier, Ahmed Benyoucef, Thomas Lacornerie, David Pasquier, David Pasquier, Séverine Racadot, Alexandra Moignier, François Paris, François Paris, Fabrice André, Fabrice André, Eric Deutsch, Eric Deutsch, Boris Duchemann, Rodrigue Setcheou Allodji, Rodrigue Setcheou Allodji, Rodrigue Setcheou Allodji, Sofia Rivera, Sofia Rivera

“…In the multivariable analysis adjusted for chemotherapy use and nodal involvement, pulmonary medical history (OR=3.05, p&lt;0.01) and high V30 Gy (OR=1.06, p=0.04) remained statistically significant risk factors for RILI occurrence. …”
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Neuromuscular Fatigue and Metabolic Stress during the 15 Minutes of Rest after Carrying Out a Bench Press Exercise Protocol by Juan Hernández-Lougedo, Juan Ramón Heredia-Elvar, Luis Maicas-Pérez, Ana María Cañuelo-Márquez, Manuel Rozalén-Bustín, Fernando de Jesús Franco, Manuel Vicente Garnacho-Castaño, Pablo García-Fernández, José Luis Maté-Muñoz

“…However, the blood lactate levels are still high (>5 mmol·L⁻¹). Therefore, although there seem to be certain conditions to reach a similar maximum MPV peak, the residual fatigue at the neuromuscular level and the non-recovery of metabolic homeostasis would hinder the reproduction of these protocols, both at the level of applied stimulus and from a methodological perspective, since a long recovery time would be required between sets and exercises.…”
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Integrated MRI–Immune–Genomic Features Enclose a Risk Stratification Model in Patients Affected by Glioblastoma by Giulia Mazzaschi, Alessandro Olivari, Antonio Pavarani, Costanza Anna Maria Lagrasta, Caterina Frati, Denise Madeddu, Bruno Lorusso, Silvia Dallasta, Chiara Tommasi, Antonino Musolino, Marcello Tiseo, Maria Michiara, Federico Quaini, Pellegrino Crafa

“…Conversely, the density of vascular-associated (V) CD4+ lymphocytes emerged as the most significant prognostic factor (median OS = 23 months in V-CD4^high vs. 13 months in V-CD4^low, <i>p</i> = 0.015). High V-CD4+TILs also characterized TIME of MGMT^meth GB, while p53^mut appeared to condition a desert immune background. …”
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Cardiovascular Health in India – a Report Card from Three Urban and Rural Surveys of 22,144 Adults by Roopa Shivashankar, Kalpana Singh, Dimple Kondal, Ruby Gupta, Pablo Perel, Deksha Kapoor, Devraj Jindal, Sailesh Mohan, Rajendra Pradeepa, Prashant Jarhyan, Nikhil Srinivasapura Venkateshmurthy, Nikhil Tandon, Viswanathan Mohan, K. M. Venkat Narayan, Dorairaj Prabhakaran, Mohammed K. Ali

“…Adjusted prevalence of good, moderate, and poor CVH, varied across settings: metropolitan (3.9%, 41.0%, and 55.1%), smaller cities (7.8%, 49.2%, and 43%), and rural (10.4%, 60.9%, and 28.7%) and across asset tertiles: Low (11.0%, 55.9%, 33.1%), Middle (6.3%, 52.2%, 41.5%), and High (5.0%, 46.4%, 48.7%), respectively. Conclusion: Achievement of ideal CVH varied, with higher prevalence in rural and lower asset tertiles. …”
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Africa Digest : Trends and issues in macro environment Vol. 7 by Burger, Johan

“…The UN’s Sustainable Development Goals, the AU’s Agenda 2063 and the African Development Banks’ High 5 Priorities all connect with this challenge in one way or another. …”
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Formulasi Strategi Bersaing PT. Mitsubishi Jaya Elevator dan Escalator by , Eva Suryaman, , Dr. Hani Handoko, MBA

“…Analysis of industrial environments of PT Mitsubishi Jaya Elevator and Escalator are: (1) the threat of new entrants is low, (2) the intensity of high industry competition, (3) threat of substitute products is very low, (4) bargaining power of suppliers is very high, (5) bargaining power of buyers is low. Analysis of internal environment of PT Mitsubishi Jaya Elevator and Escalator are: (1) production of raw material quality, (2) Quality control is very tight from Melina Japan, (3) technicians are competent, (4) the production process is monitored closely by Melina, (5) quality production equipment and machinery according to the standard from MC, (6) experienced workforce, (7) has 8 branch offices throughout Indonesia, which facilitate the installation of aftermarket products and services, (8) has many loyal customers, (9) installation and after sales service is fast and reliable by experienced technicians, (10) companies have good management system and coordinated, (11) brand name and strong corporate image, (12) Good human resource development, (13) advanced technology, (14 ) research and development, (15) is the sole distributor. …”

Metal hyperaccumulation in plants: mechanisms of defence against insect herbivores by Behmer, S, Lloyd, C, Raubenheimer, D, Stewart-Clark, J, Knight, J, Leighton, R, Harper, F, Smith, J

“…In choice experiments, locusts preferred T. caerulescens plants containing low foliar Zn concentrations (mean value 0.42 mg g-1 dry biomass) compared with intermediate (1.50 mg g-1) or high (5.77 mg g-1) Zn concentrations. In no-choice experiments, there was no difference in the duration of the first meal, suggesting that locusts could not taste Zn directly, but total time spent feeding, amount of foliage eaten, and locust growth rate all decreased as foliar Zn concentration increased. 3. …”

Primaquine radical cure of Plasmodium vivax: a critical review of the literature. by John, G, Douglas, N, von Seidlein, L, Nosten, F, Baird, J, White, N, Price, R

“…Primaquine regimens were categorized according to the total dose administered: very low (≤2.5 mg/kg), low (&gt;2.5 mg/kg- &lt; 5.0 mg/kg) and high (≥ 5.0 mg/kg). The risk of recurrent infection were summarized across geographical regions and the odds ratios between treatment regimens calculated after stratifying by total treatment dose and duration of study follow up. …”