Home and away- the evolutionary dynamics of homing endonucleases by Barzel Adi, Obolski Uri, Gogarten Johann, Kupiec Martin, Hadany Lilach

“…<p>Abstract</p> <p>Background</p> <p>Homing endonucleases (HEases) are a large and diverse group of site-specific DNAases. …”
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Structural Basis for the Propagation of Homing Endonuclease-Associated Inteins by Hannes M. Beyer, Hannes M. Beyer, Hideo Iwaï

“…We elucidated the crystal structures of two archaeal inteins associated with an active or inactive homing endonuclease domain. This analysis illustrated structural diversity in the accessory domains (ACDs) associated with the homing endonuclease domain. …”
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The design and mechanism of synthetic homing endonuclease gene drives by Verkuijl, S

Requirements for effective malaria control with homing endonuclease genes. by Deredec, A, Godfray, H, Burt, A

“…We have previously proposed that biological approaches to control the mosquito vector of disease could be developed using homing endonuclease genes (HEGs), a class of selfish or parasitic gene that exists naturally in many microbes. …”

The Challenges in Developing Efficient and Robust Synthetic Homing Endonuclease Gene Drives by Sebald A. N. Verkuijl, Sebald A. N. Verkuijl, Joshua X. D. Ang, Luke Alphey, Michael B. Bonsall, Michelle A. E. Anderson

“…We conclude by discussing the progress made in developing strategies to increase the efficiency of homing endonuclease gene drives and mitigate or prevent unintended outcomes.…”
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The population genetics of using homing endonuclease genes in vector and pest management. by Deredec, A, Burt, A, Godfray, H

“…Homing endonuclease genes (HEGs) encode proteins that in the heterozygous state cause double-strand breaks in the homologous chromosome at the precise position opposite the HEG. …”

The challenges in developing efficient and robust synthetic homing endonuclease gene drives by Verkuijl, S, Ang, J, Alphey, L, Bonsall, M, Anderson, M

“…We conclude by discussing the progress made in developing strategies to increase the efficiency of homing endonuclease gene drives and mitigate or prevent unintended outcomes.…”

HEHR: Homing Endonuclease-Mediated Homologous Recombination for Efficient Adenovirus Genome Engineering by Katrin Schröer, Fatima Arakrak, Annika Bremke, Anja Ehrhardt, Wenli Zhang

“…Based on our previously reported adenoviral genome modification streamline via linear–circular homologous recombination, we further develop an HEHR (combining Homing Endonucleases and Homologous Recombination) method to engineer adenoviral genomes more efficiently. …”
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Using Group II Introns for Attenuating the In Vitro and In Vivo Expression of a Homing Endonuclease. by Tuhin Kumar Guha, Georg Hausner

“…This arrangement offers the opportunity to examine if the nested group II intron could be utilized as a regulatory element for the expression of the homing endonuclease (HEase). Constructs were generated where the codon-optimized ORF was interrupted with either the native group IIA1 intron or a group IIB type intron. …”
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In vitro Inactivation of Latent HSV by Targeted Mutagenesis Using an HSV-specific Homing Endonuclease by Martine Aubert, Nicole M Boyle, Daniel Stone, Laurence Stensland, Meei-Li Huang, Amalia S Magaret, Roman Galetto, David J Rawlings, Andrew M Scharenberg, Keith R Jerome

“…We tested this approach in an in vitro HSV latency model using the engineered homing endonuclease (HE) HSV1m5, which recognizes a sequence in the HSV-1 gene UL19, encoding the virion protein VP5. …”
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iBrick: a new standard for iterative assembly of biological parts with homing endonucleases. by Jia-Kun Liu, Wei-Hua Chen, Shuang-Xi Ren, Guo-Ping Zhao, Jin Wang

“…Here, we introduce a new standard, namely iBrick, which uses two homing endonucleases of I-SceI and PI-PspI. Because both enzymes recognize long DNA sequences (>18 bps), their sites are extremely rare in natural DNA sources, thus providing additional convenience, especially in handling large pieces of DNA fragments. …”
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Editorial: The Significance of Mitogenomics in Mycology by Tomasz Kulik, Anne D. Van Diepeningen, Georg Hausner

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Genome-wide characterization of <it>vibrio</it> phage ϕpp2 with unique arrangements of the <it>mob</it>-like genes by Lin Ying-Rong, Lin Chan-Shing

Subjects: “…Homing endonuclease…”
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Inteins, introns, and homing endonucleases: recent revelations about the life cycle of parasitic genetic elements by Hilario Elena, Gogarten J Peter

“…<p>Abstract</p> <p>Self splicing introns and inteins that rely on a homing endonuclease for propagation are parasitic genetic elements. …”
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In vivo characterization of the homing endonuclease within the polB gene in the halophilic archaeon Haloferax volcanii. by Adit Naor, Rona Lazary, Adi Barzel, R Thane Papke, Uri Gophna

“…Many inteins contain a homing endonuclease (HEN) gene, and rely on its activity for horizontal propagation. …”
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Promising prospects of nanopore sequencing for algal hologenomics and structural variation discovery by Thomas Sauvage, William E. Schmidt, Hwan Su Yoon, Valerie J. Paul, Suzanne Fredericq

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Structural Organization of S516 Group I Introns in Myxomycetes by Betty M. N. Furulund, Bård O. Karlsen, Igor Babiak, Peik Haugen, Steinar D. Johansen

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F-CphI represents a new homing endonuclease family using the Endo VII catalytic motif by Xiaoting Fang, YongLiang Jiang, Kim Li, Qinglu Zeng

Subjects: “…Homing endonuclease…”
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Mobile group I introns at nuclear rDNA position L2066 harbor sense and antisense homing endonuclease genes intervened by spliceosomal introns by Kjersti Lian, Betty M. N. Furulund, Anders A. Tveita, Peik Haugen, Steinar D. Johansen

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Global Characterization of Fungal Mitogenomes: New Insights on Genomic Diversity and Dynamism of Coding Genes and Accessory Elements by Paula L. C. Fonseca, Paula L. C. Fonseca, Ruth B. De-Paula, Daniel S. Araújo, Luiz Marcelo Ribeiro Tomé, Thairine Mendes-Pereira, Wenderson Felipe Costa Rodrigues, Luiz-Eduardo Del-Bem, Luiz-Eduardo Del-Bem, Eric R. G. R. Aguiar, Aristóteles Góes-Neto, Aristóteles Góes-Neto

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