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<i>RAD52</i> Functions in Homologous Recombination and Its Importance on Genomic Integrity Maintenance and Cancer Therapy
Published 2019-10-01Subjects: Get full text
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222
Regulation of DNA Damage Response and Homologous Recombination Repair by microRNA in Human Cells Exposed to Ionizing Radiation
Published 2020-07-01“…As an important element of this, homologous recombination repair is a crucial pathway for the error-free repair of DNA lesions. …”
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An expanded toolkit for Drosophila gene tagging using synthesized homology donor constructs for CRISPR-mediated homologous recombination
Published 2022-06-01Subjects: Get full text
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225
Rapid generation of long tandem DNA repeat arrays by homologous recombination in yeast to study their function in mammalian genomes
Published 2011-10-01“…This method includes rolling-circle phi29 amplification (RCA) of the sequence <it>in vitro </it>and assembly of the RCA products <it>in vivo </it>by homologous recombination in the yeast <it>Saccharomyces cerevisiae</it>. …”
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226
1,6-Hexanediol Is Inducing Homologous Recombination by Releasing BLM from Assemblysomes in <i>Drosophila melanogaster</i>
Published 2024-01-01Subjects: Get full text
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227
Impact of homologous recombination deficiency biomarkers on outcomes in patients with early breast cancer: a systematic review protocol
Published 2022-08-01“…Introduction Patients with breast cancer with homologous recombination deficiency (HRD) such as germline BRCA1/2 mutations would respond to DNA-damaging drugs. …”
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228
MED1, a novel binding partner of BRCA1, regulates homologous recombination and R-loop processing
Published 2022-10-01“…Abstract Homologous recombination (HR) is a major repair pathway of DNA double-strand breaks and is closely related to carcinogenesis. …”
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229
Cascade-Cas3 facilitates high-accuracy genome engineering in Pseudomonas using phage-encoded homologous recombination
Published 2022-12-01Subjects: “…Phage-encoded homologous recombination…”
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Using single loxP sites to enhance homologous recombination: ts mutants in Sec1 of Dictyostelium discoideum.
Published 2007-08-01“…The success of this approach depended on the high level of homologous recombination prevailing at this locus: approximately 95% of selected clones were homologous recombinants. …”
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232
Division of Labor by the HELQ, BLM, and FANCM Helicases during Homologous Recombination Repair in <i>Drosophila melanogaster</i>
Published 2022-03-01“…Repair of DNA double-strand breaks by homologous recombination (HR) requires a carefully orchestrated sequence of events involving many proteins. …”
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Uncovering the role of Rad51 in homologous recombination-mediated antigenic diversification in the human malaria parasite Plasmodium falciparum
Published 2023-08-01“…The most prominent molecular determinant of antigenic variation in this parasite includes the members of the var multigene family. Homologous recombination (HR)-mediated genomic rearrangements have been implicated to play a major role in var gene diversification. …”
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Large chromosomal deletions and impaired homologous recombination repairing in HEK293T cells exposed to polychlorinated biphenyl 153
Published 2021-07-01Subjects: Get full text
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236
HRD-MILN: Accurately estimate tumor homologous recombination deficiency status from targeted panel sequencing data
Published 2022-09-01Subjects: “…homologous recombination deficiency…”
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237
Classification of High-Grade Serous Ovarian Carcinoma by Epithelial-to-Mesenchymal Transition Signature and Homologous Recombination Repair Genes
Published 2021-07-01Subjects: Get full text
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238
Protocol for Efficient CRISPR/Cas9/AAV-Mediated Homologous Recombination in Mouse Hematopoietic Stem and Progenitor Cells
Published 2020-06-01“…To model such disorders in mice, we developed a CRISPR/Cas9/adeno-associated virus (AAV)-based system to knock in and repair genes by homologous recombination in mouse HSPCs. Here, we provide a step-by-step protocol to achieve high efficiency of gene knockin in mouse HSPCs, while maintaining engraftment capacity. …”
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Homologous Recombination-Enhancing Factors Identified by Comparative Transcriptomic Analyses of Pluripotent Stem Cell of Human and Common Marmoset
Published 2022-01-01Subjects: Get full text
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Construction of A High-efficiency Homologous Recombination and Uridine/Uracil Auxotroph Strain of Aspergillus oryzae RIB40
Published 2023-01-01“…Objective: An auxotrophic strain with high efficiency of homologous recombination was developed in Aspergillus oryzae RIB40. …”
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