-
421
Low dose PFDA induces DNA damage and DNA repair inhibition by promoting nuclear cGAS accumulation in ovarian epithelial cells
Published 2023-10-01Subjects: Get full text
Article -
422
-
423
Involvement of POLA2 in Double Strand Break Repair and Genotoxic Stress
Published 2020-06-01Subjects: Get full text
Article -
424
USP14 Regulates DNA Damage Response and Is a Target for Radiosensitization in Non-Small Cell Lung Cancer
Published 2020-09-01Subjects: Get full text
Article -
425
Establishment, optimization, and application of genetic technology in Aspergillus spp.
Published 2023-03-01Subjects: Get full text
Article -
426
What role do biocontrol agents with Mg2+ play in the fate of antibiotic resistome and pathogenic bacteria in the phyllosphere?
Published 2024-04-01Subjects: Get full text
Article -
427
The Landscape and Therapeutic Targeting of <i>BRCA1</i>, <i>BRCA2</i> and Other DNA Damage Response Genes in Pancreatic Cancer
Published 2023-03-01Subjects: Get full text
Article -
428
WNT inhibition creates a BRCA‐like state in Wnt‐addicted cancer
Published 2021-04-01Subjects: Get full text
Article -
429
Plasticity of repetitive sequences demonstrated by the complete mitochondrial genome of Eucalyptus camaldulensis
Published 2024-03-01Subjects: Get full text
Article -
430
Application of long single-stranded DNA donors in genome editing: generation and validation of mouse mutants
Published 2018-06-01Subjects: Get full text
Article -
431
Horizontal Gene Transfer, Dispersal and Haloarchaeal Speciation
Published 2015-05-01Subjects: Get full text
Article -
432
Older age should not be a barrier to testing for somatic variants in homologous recombination DNA repair-related genes in patients with high-grade serous ovarian carcinoma
Published 2023-05-01“…Background: Somatic pathogenic variants (PVs) in homologous recombination DNA repair (HR)-related genes found in high-grade serous ovarian carcinomas (HGSC) are not well-characterised in older patients (≥70 years). …”
Get full text
Article -
433
ATR-binding lncRNA ScaRNA2 promotes cancer resistance through facilitating efficient DNA end resection during homologous recombination repair
Published 2023-09-01“…Results ScaRNA2 was identified as the most enriched ATR-binding lncRNA and was found to be essential for homologous recombination (HR) mediated DNA damage repair. Furthermore, scaRNA2 knockdown abrogated the recruitment of ATR and its substrates in response to DNA damage. …”
Get full text
Article -
434
-
435
A Novel Non-Allelic Homologous Recombination Event in a Parent with an 11;22 Reciprocal Translocation Leading to 22q11.2 Deletion Syndrome
Published 2022-09-01“…Most individuals with 22q11.2 deletion syndrome (22q11.2DS) carry a de novo, hemizygous deletion approximately 3 Mbp in size occurring by non-allelic homologous recombination (NAHR) mediated by the LCR22s. The ability to fully delineate an individual’s 22q11.2 regional structure will likely be important for studies designed to assess an unaffected individual’s risk for generating rearrangements in germ cells, potentially leading to offspring with 22q11.2DS. …”
Get full text
Article -
436
-
437
-
438
A Homologous Recombination System to Generate Epitope-Tagged Target Genes in <i>Chaetomium thermophilum</i>: A Genetic Approach to Investigate Native Thermostable Proteins
Published 2022-03-01Subjects: “…homologous recombination (HR)…”
Get full text
Article -
439
The Largest Chinese Cohort Study Indicates Homologous Recombination Pathway Gene Mutations as Another Major Genetic Risk Factor for Colorectal Cancer with Heterogeneous Clinical Phenotypes
Published 2023-01-01“…Mismatch repair gene mutation was identified in 9.1% of patients, most prevalent across all high-risk groups. Homologous recombination (HR) gene mutations were detected in 6.5% of cases, penetrated in early-onset and extra-colonic cancer risk groups. …”
Get full text
Article -
440
Functional Homologous Recombination (HR) Screening Shows the Majority of <i>BRCA1/2</i>-Mutant Breast and Ovarian Cancer Cell Lines Are HR-Proficient
Published 2024-02-01Subjects: “…homologous recombination repair…”
Get full text
Article