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Homologous Recombination: A GRAS Yeast Genome Editing Tool
Published 2020-06-01Subjects: “…homologous recombination…”
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No observed effect of homologous recombination on influenza C virus evolution.
Published 2010“…The occurrence of homologous recombination in influenza viruses has been under some debate recently. …”
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Analysis of nucleotide synthesis and homologous recombination repair in Schizosaccharomyces pombe
Published 2014“…<p>Nucleotide synthesis is a conserved and highly regulated response to DNA damage, required for the efficient repair of DNA double strand breaks (DSB) by homologous recombination (HR). This is essential to prevent loss of heterozygosity (LOH) and maintain genome stability. …”
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Inference of homologous recombination in bacteria using whole-genome sequences.
Published 2010Journal article -
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SimBac: simulation of whole bacterial genomes with homologous recombination
Published 2015“…We present SimBac, a whole-genome bacterial evolution simulator that is roughly two orders of magnitude faster than previous software and includes a more general model of bacterial evolution, allowing both within- and between-species homologous recombination. Since methods modeling bacterial recombination generally focus on only one of these two modes of recombination, the possibility to simulate both allows for a general and fair benchmarking. …”
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Frequent homologous recombination deficiency in high-grade endometrial carcinomas
Published 2018“…We sought to assess the prevalence of homologous recombination deficiency (HRD) in EC and its association with histopathological and molecular characteristics.…”
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Guidelines for identifying homologous recombination events in influenza A virus
Published 2010“…Here, we review the necessary criteria related to laboratory procedures and sample handling, bioinformatic analysis, and the known ecology and evolution of influenza viruses that need to be met in order to confirm that a homologous recombination event occurred in the history of a set of sequences. …”
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Guidelines for identifying homologous recombination events in influenza A virus.
Published 2010“…We conclude that the presence of false positive signals in the non-IGSP data is more likely than false negatives in the IGSP data, and that given the evidence to date, homologous recombination seems to play little or no role in the evolution of influenza A viruses.…”
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Characteristics of homologous recombination repair pathway genes mutation in ovarian cancers
Published 2022-10-01Subjects: Get full text
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Unveiling novel RecO distant orthologues involved in homologous recombination.
Published 2008-08-01“…The generation of a RecA filament on single-stranded DNA is a critical step in homologous recombination. Two main pathways leading to the formation of the nucleofilament have been identified in bacteria, based on the protein complexes mediating RecA loading: RecBCD (AddAB) and RecFOR. …”
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Constructing founder sets under allelic and non-allelic homologous recombination
Published 2023-09-01Subjects: Get full text
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Study of the homologous recombination genetic system to improve genetic transformation of wheat
Published 2005-12-01Subjects: “…homologous recombination…”
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Homologous Recombination and Repair Functions Required for Mutagenicity during Yeast Meiosis
Published 2023-10-01Subjects: Get full text
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Prediction of homologous recombination deficiency from cancer gene expression data
Published 2022-11-01“…Objective Homologous recombination deficiency (HRD) is the main mechanism of tumorigenesis in some cancers. …”
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Race-Specific Genetic Profiles of Homologous Recombination Deficiency in Multiple Cancers
Published 2021-12-01Subjects: “…homologous recombination deficiency…”
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Fusing an exonuclease with Cas9 enhances homologous recombination in Pichia pastoris
Published 2022-09-01“…However, low homologous recombination (HR) efficiency hinders its precise and extensive genetic manipulation. …”
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Patient Assessment and Therapy Planning Based on Homologous Recombination Repair Deficiency
Published 2023-10-01Subjects: Get full text
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New RAD51 Inhibitors to Target Homologous Recombination in Human Cells
Published 2021-06-01Subjects: Get full text
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WIP1 Promotes Homologous Recombination and Modulates Sensitivity to PARP Inhibitors
Published 2019-10-01“…Here we show that WIP1 promotes DNA repair through homologous recombination. Loss or inhibition of WIP1 delayed disappearance of the ionizing radiation-induced 53BP1 foci in S/G2 cells and promoted cell death. …”
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PCNA Unloading Is Crucial for the Bypass of DNA Lesions Using Homologous Recombination
Published 2024-03-01“…In contrast, SUMOylation recruits the Srs2 helicase, which prevents local homologous recombination. The Elg1 RFC-like complex plays an important role in unloading PCNA from the chromatin. …”
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