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The histone modification reader ZCWPW1 links histone methylation to PRDM9-induced double-strand break repair
Published 2020-05-01Subjects: Get full text
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584
A new insight into RecA filament regulation by RecX from the analysis of conformation-specific interactions
Published 2022-06-01Subjects: Get full text
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585
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586
Homologous Recombination Deficiency (HRD) Scoring, by Means of Two Different Shallow Whole-Genome Sequencing Pipelines (sWGS), in Ovarian Cancer Patients: A Comparison with Myriad MyChoice Assay
Published 2023-12-01“…High-grade serous ovarian cancer (HGSOC) patients carrying the <i>BRCA1/2</i> mutation or deficient in the homologous recombination repair system (HRD) generally benefit from treatment with PARP inhibitors. …”
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587
Multi-Gene Next-Generation Sequencing Panel for Analysis of <i>BRCA1</i>/<i>BRCA2</i> and Homologous Recombination Repair Genes Alterations Metastatic Castration-Resistant Prostate Cancer
Published 2023-05-01“…Mutations in homologous recombination repair (HRR) genes are frequent in mCRPC, and tumors harboring these mutations are known to be sensitive to PARP inhibitors. …”
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588
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Genomic Instability Is Defined by Specific Tumor Microenvironment in Ovarian Cancer: A Subgroup Analysis of AGO OVAR 12 Trial
Published 2022-02-01Subjects: Get full text
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590
A novel G3BP1-GFP reporter human lung cell system enabling real-time monitoring of stress granule dynamics for in vitro lung toxicity assessment
Published 2024-01-01Subjects: Get full text
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591
Taking a Bad Turn: Compromised DNA Damage Response in Leukemia
Published 2017-05-01Subjects: Get full text
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592
Generation and Characterization of a Replication-Competent Human Adenovirus Type 55 Encoding EGFP
Published 2023-05-01Subjects: Get full text
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593
Interactions between miRNAs and Double-Strand Breaks DNA Repair Genes, Pursuing a Fine-Tuning of Repair
Published 2022-03-01Subjects: Get full text
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594
Clinical Landscape of PARP Inhibitors in Ovarian Cancer: Molecular Mechanisms and Clues to Overcome Resistance
Published 2022-05-01Subjects: Get full text
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595
HRD Testing of Ovarian Cancer in Routine Practice: What Are We Dealing With?
Published 2023-06-01Subjects: “…homologous recombination deficiency…”
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596
The Versatile Attributes of MGMT: Its Repair Mechanism, Crosstalk with Other DNA Repair Pathways, and Its Role in Cancer
Published 2024-01-01Subjects: Get full text
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597
DNA Damage Response in Multiple Myeloma: The Role of the Tumor Microenvironment
Published 2021-01-01Subjects: Get full text
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598
DNA double-strand break genetic variants in patients with premature ovarian insufficiency
Published 2023-07-01Subjects: Get full text
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599
Concurrent loss of MLH1, PMS2 and MSH6 immunoexpression in digestive system cancers indicating a widespread dysregulation in DNA repair processes
Published 2022-10-01Subjects: Get full text
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600
PARP Inhibitors in Patients With Newly Diagnosed Advanced Ovarian Cancer: A Meta-Analysis of Randomized Clinical Trials
Published 2020-08-01Subjects: Get full text
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