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DNA repair synthesis and histone deposition partner during homologous recombination
Published 2018-09-01Subjects: Get full text
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62
The Hop2-Mnd1 Complex and Its Regulation of Homologous Recombination
Published 2023-04-01Subjects: Get full text
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63
STAG2 Regulates Homologous Recombination Repair and Sensitivity to ATM Inhibition
Published 2023-12-01Subjects: Get full text
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64
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Fast multiple gene fragment ligation method based on homologous recombination
Published 2010“…BBF RFC 62 is developed aimed at completing the ligation of multiple fragments quickly and efficiently based on homologous recombination.…”
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Technical Report -
66
Harnessing mutagenic homologous recombination for targeted mutagenesis in vivo by TaGTEAM
Published 2013“…We provide evidence that TaGTEAM generated point mutations occur through error-prone homologous recombination (HR) and depend on resectioning and the error-prone polymerase Pol ζ. …”
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P53 gene targeting by homologous recombination in fish ES cells
Published 2013“…We have previously established ES cell lines and procedures for gene transfer and selection for homologous recombination (HR) events in the fish medaka (Oryzias latipes). …”
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Journal Article -
69
Identification of the MMS22L-TONSL complex that promotes homologous recombination.
Published 2010“…Budding yeast Mms22 is required for homologous recombination (HR)-mediated repair of stalled or broken DNA replication forks. …”
Journal article -
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Interplay between Fanconi anemia and homologous recombination pathways in genome integrity
Published 2016“…The Fanconi anemia (FA) pathway plays a central role in the repair of DNA interstrand crosslinks (ICLs) and regulates cellular responses to replication stress. Homologous recombination (HR), the error-free pathway for double-strand break (DSB) repair, is required during physiological cell cycle progression for the repair of replication-associated DNA damage and protection of stalled replication forks. …”
Journal article -
71
Pathways for Holliday junction processing during homologous recombination in Saccharomyces cerevisiae.
Published 2011“…Following a transient exposure to methyl methanesulfonate, rmi1-1 mutants accumulate unprocessed homologous recombination repair (HRR) intermediates. These intermediates are slowly resolved at the restrictive temperature, revealing a redundant resolution activity when Rmi1 is impaired. …”
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EXD2 promotes homologous recombination by facilitating DNA end resection
Published 2016“…Repair of DNA double-strand breaks (DSBs) by homologous recombination (HR) is critical for survival and genome stability of individual cells and organisms, but also contributes to the genetic diversity of species. …”
Journal article -
73
Homologous Recombination Is Very Rare or Absent in Human Influenza A Virus
Published 2008Journal article -
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[Regulation of homologous recombination: old and new roles of cyclin-dependent kinases].
Published 2009Journal article -
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Poly(ADP-ribose) polymerase is hyperactivated in homologous recombination-defective cells.
Published 2010“…Inhibitors of PARP efficiently kill breast, ovarian, or prostate tumors in patients carrying hereditary mutations in the homologous recombination (HR) genes BRCA1 or BRCA2 through synthetic lethality. …”
Journal article -
76
Homologous Recombination Deficiency Score Determined by Genomic Instability in a Romanian Cohort
Published 2023-05-01Subjects: “…homologous recombination deficiency…”
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77
Optimized detection of homologous recombination deficiency improves the prediction of clinical outcomes in cancer
Published 2022-12-01“…Abstract Homologous recombination DNA-repair deficiency (HRD) is a common driver of genomic instability and confers a therapeutic vulnerability in cancer. …”
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Genomic and molecular landscape of homologous recombination deficiency across multiple cancer types
Published 2023-06-01“…Abstract Homologous recombination deficiency (HRD) causes faulty double-strand break repair and is a prevalent cause of tumorigenesis. …”
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79
Exploiting the Prevalence of Homologous Recombination Deficiencies in High-Grade Serous Ovarian Cancer
Published 2020-05-01Get full text
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80
RBM14 promotes DNA end resection during homologous recombination repair
Published 2023-08-01Subjects: Get full text
Article