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101
Nucleoporin 54 contributes to Homologous recombination repair and post-replicative DNA integrity
Published 2018“…Interestingly, we found that Nup54 is epistatic with the Homologous Recombination (HR) factor Rad51. Moreover, using specific DNA damage repair reporters, we observed a decreased HR repair activity upon Nup54 knockdown. …”
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102
Roles for APRIN (PDS5B) in homologous recombination and in ovarian cancer prediction
Published 2016“…APRIN is a new homologous recombination (HR) mediator as it counteracts the RPA inhibitory effect on RAD51 loading to ssDNA. …”
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103
The involvement of Srs2 in post-replication repair and homologous recombination in fission yeast.
Published 2004“…Homologous recombination is important for the repair of double-strand breaks and daughter strand gaps, and also helps restart stalled and collapsed replication forks. …”
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104
Screening for inhibitors of and novel proteins within the homologous recombination DNA repair pathway
Published 2012“…The homologous recombination (HR) pathway of DNA repair is essential for the faithful repair of double-stranded DNA breaks (DSBs) in all organisms and as such helps maintain genomic stability. …”
Thesis -
105
Determination of BRCAness Phenotype in Breast Tumors for the Appointment of Neoadjuvant Chemotherapy Based on Platinum and Taxanes
Published 2022-12-01Subjects: Get full text
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106
Moderate-Risk Genes for Hereditary Ovarian Cancers Involved in the Homologous Recombination Repair Pathway
Published 2022-10-01Subjects: Get full text
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107
Copy number alteration features in pan-cancer homologous recombination deficiency prediction and biology
Published 2023-05-01“…Abstract Homologous recombination deficiency (HRD) renders cancer cells vulnerable to unrepaired double-strand breaks and is an important therapeutic target as exemplified by the clinical efficacy of poly ADP-ribose polymerase (PARP) inhibitors as well as the platinum chemotherapy drugs applied to HRD patients. …”
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108
The Homologous Recombination Deficiency Scar in Advanced Cancer: Agnostic Targeting of Damaged DNA Repair
Published 2022-06-01Subjects: “…homologous recombination deficiency…”
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109
Combination of FACS and homologous recombination for the generation of stable and high-expression engineered cell lines.
Published 2014-01-01“…Here, we have designed a new strategy for the generation of stable and high-expression cell lines by combining homologous recombination (HR) and fluorescence-activated cell sorting (FACS). …”
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110
Homologous recombination repair rathway and RAD54L in early-stage lung adenocarcinoma
Published 2021-02-01Subjects: Get full text
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111
Homologous Recombination Repair Gene Alterations Are Associated with Tumor Mutational Burden and Survival of Immunotherapy
Published 2023-11-01Subjects: “…homologous recombination repair gene…”
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112
Competitive repair by naturally dispersed repetitive DNA during non-allelic homologous recombination.
Published 2010-12-01“…Genome rearrangements often result from non-allelic homologous recombination (NAHR) between repetitive DNA elements dispersed throughout the genome. …”
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113
Essential role of the BRCA2B gene in somatic homologous recombination in Arabidopsis thaliana
Published 2023-12-01Subjects: Get full text
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114
Prevalent role of homologous recombination in the repair of specific double-strand breaks in Rhizobium etli
Published 2024-02-01“…Repair of a DSB may be achieved through homologous recombination (either between adjacent or distant repeats) or NHEJ. …”
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115
Mutations in Homologous Recombination Genes and Loss of Heterozygosity Status in Advanced-Stage Breast Carcinoma
Published 2023-04-01Subjects: Get full text
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116
Loss of CENP-I Impairs Homologous Recombination and Sensitizes Cells to PARP1 Inhibition
Published 2021-06-01Subjects: Get full text
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117
First Isolation and Identification of Homologous Recombination Events of Porcine Adenovirus from Wild Boar
Published 2022-10-01Subjects: Get full text
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118
Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors
Published 2020-06-01“…Here, we show that homologous recombination‐defective (HRD) cancers rely on oxidative metabolism to supply NAD+ and ATP for poly(ADP‐ribose) polymerase (PARP)‐dependent DNA repair mechanisms. …”
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119
Homologous recombination deficiency signatures in gastrointestinal and thoracic cancers correlate with platinum therapy duration
Published 2023-03-01“…Abstract There is emerging evidence about the predictive role of homologous recombination deficiency (HRD), but this is less defined in gastrointestinal (GI) and thoracic malignancies. …”
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120
Parental histone distribution and location of the replication obstacle at nascent strands control homologous recombination
Published 2023-03-01“…Therefore, parental histone distribution and location of the replication obstacle at the lagging or leading strand regulate homologous recombination.…”
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Article