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The Regulation of Homologous Recombination by Helicases
Published 2020-05-01“…Homologous recombination is essential for DNA repair, replication and the exchange of genetic material between parental chromosomes during meiosis. …”
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2
Chromosome architecture and homologous recombination in meiosis
Published 2023-01-01Get full text
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3
Biomarkers for Homologous Recombination Deficiency in Cancer
Published 2021-06-01Subjects: Get full text
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4
Homologous Recombination Deficiencies and Hereditary Tumors
Published 2021-12-01Subjects: “…homologous recombination deficiency (HRD)…”
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5
Selective targeting of homologous recombination deficiency
Published 2014“…<p>Homologous recombination (HR) is a key DNA repair pathway essential for cell viability. …”
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ASYNAPSIS 1 ensures crossover fidelity in polyploid wheat by promoting homologous recombination and suppressing non-homologous recombination
Published 2023-05-01“…During meiosis, the chromosome axes and synaptonemal complex mediate chromosome pairing and homologous recombination to maintain genomic stability and accurate chromosome segregation. …”
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Targeting homologous recombination deficiency in uterine leiomyosarcoma
Published 2023-05-01Subjects: Get full text
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8
Determinants of Homologous Recombination Deficiency in Pancreatic Cancer
Published 2021-09-01Subjects: “…homologous recombination deficiency…”
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Leveraging homologous recombination repair deficiency in sarcoma
Published 2023-04-01“…Many cancers are deficient in high‐fidelity DNA repair pathways that maintain genomic stability, such as homologous recombination (HR). Such cancers are highly sensitive to targeted therapies that induce DNA damage or inhibit DNA repair pathways. …”
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Homologous Recombination Deficiency (HRD) in Cutaneous Oncology
Published 2023-06-01Subjects: Get full text
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The analysis of homologous recombination pathways in Saccharomyces Cerevisiae
Published 2010“…<p>Homologous recombination (HR) is essential for the repair of DNA doublestrand breaks (DSBs) and damaged replication forks. …”
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Investigating the role of homologous recombination at human centromeres
Published 2022“…</p> <p>Secondly, building on a growing body of evidence suggesting that centromeres are unusually prone to spontaneous recombination, I examined the role of the repair pathway homologous recombination (HR) at human centromeres. I demonstrate that the central mammalian recombinase RAD51 suppresses DNA break accumulation in a manner dependent on its recombination activity, providing molecular evidence for the recombination processes proposed to occur at human centromeres.…”
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How homologous recombination maintains telomere integrity
Published 2015“…In addition to providing a pathway for genome-wide DNA repair, homologous recombination (HR) plays a key role in telomere replication and capping. …”
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An Improved Homologous Recombination Method for Rapid Cloning of the Antibody Heavy Chain Gene and Its Comparison with the Homologous Recombination and Traditional Cloning Methods
Published 2015-10-01Subjects: “…Homologous recombination, Gene cloning, Heat , pcDNA3.1, IgG1…”
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Assembly and dynamics of the bacteriophage T4 homologous recombination machinery
Published 2010-12-01“…<p>Abstract</p> <p>Homologous recombination (HR), a process involving the physical exchange of strands between homologous or nearly homologous DNA molecules, is critical for maintaining the genetic diversity and genome stability of species. …”
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Mouse Models for Deciphering the Impact of Homologous Recombination on Tumorigenesis
Published 2021-04-01Subjects: “…homologous recombination…”
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Heterogeneity in the frequency and characteristics of homologous recombination in pneumococcal evolution.
Published 2014-05-01“…The pneumococcus is also known for undergoing extensive homologous recombination via transformation with exogenous DNA. …”
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How homologous recombination generates a mutable genome
Published 2005-09-01Subjects: “…homologous recombination…”
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Modeling the Homologous Recombination Process: Methods, Successes and Challenges
Published 2023-10-01Subjects: Get full text
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Homologous recombination risk in baculovirus expression vector system
Published 2022-11-01Subjects: Get full text
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