A modular transcriptome map of mature B cell lymphomas by Henry Loeffler-Wirth, Markus Kreuz, Lydia Hopp, Arsen Arakelyan, Andrea Haake, Sergio B. Cogliatti, Alfred C. Feller, Martin-Leo Hansmann, Dido Lenze, Peter Möller, Hans Konrad Müller-Hermelink, Erik Fortenbacher, Edith Willscher, German Ott, Andreas Rosenwald, Christiane Pott, Carsten Schwaenen, Heiko Trautmann, Swen Wessendorf, Harald Stein, Monika Szczepanowski, Lorenz Trümper, Michael Hummel, Wolfram Klapper, Reiner Siebert, Markus Loeffler, Hans Binder, for the German Cancer Aid consortium Molecular Mechanisms for Malignant Lymphoma

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Clinical Phenotype of <i>PDE6B</i>-Associated Retinitis Pigmentosa by Laura Kuehlewein, Ditta Zobor, Katarina Stingl, Melanie Kempf, Fadi Nasser, Antje Bernd, Saskia Biskup, Frans P.M. Cremers, Muhammad Imran Khan, Pascale Mazzola, Karin Schäferhoff, Tilman Heinrich, Tobias B. Haack, Bernd Wissinger, Eberhart Zrenner, Nicole Weisschuh, Susanne Kohl

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The functional O-mannose glycan on α-dystroglycan contains a phospho-ribitol primed for matriglycan addition by Jeremy L Praissman, Tobias Willer, M Osman Sheikh, Ants Toi, David Chitayat, Yung-Yao Lin, Hane Lee, Stephanie H Stalnaker, Shuo Wang, Pradeep Kumar Prabhakar, Stanley F Nelson, Derek L Stemple, Steven A Moore, Kelley W Moremen, Kevin P Campbell, Lance Wells

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The gut microbiota instructs the hepatic endothelial cell transcriptome by Henning Formes, Joana P. Bernardes, Amrit Mann, Franziska Bayer, Giulia Pontarollo, Klytaimnistra Kiouptsi, Katrin Schäfer, Sebastian Attig, Teodora Nikolova, Thomas G. Hofmann, Jörn M. Schattenberg, Hristo Todorov, Susanne Gerber, Philip Rosenstiel, Tobias Bopp, Felix Sommer, Christoph Reinhardt

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Development of multi-level standards of care recommendations for sickle cell disease: Experience from SickleInAfrica by Vivian Paintsil, Vivian Paintsil, Mwashungi Ally, Hezekiah Isa, Kofi A. Anie, Josephine Mgaya, Malula Nkanyemka, Victoria Nembaware, Yaa Gyamfua Oppong-Mensah, Flora Ndobho, Lulu Chirande, Abel Makubi, Obiageli Nnodu, Ambroise Wonkam, Julie Makani, Kwaku Ohene-Frempong

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Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA by Johannes Kettunen, Ayşe Demirkan, Peter Würtz, Harmen H.M. Draisma, Toomas Haller, Rajesh Rawal, Anika Vaarhorst, Antti J. Kangas, Leo-Pekka Lyytikäinen, Matti Pirinen, René Pool, Antti-Pekka Sarin, Pasi Soininen, Taru Tukiainen, Qin Wang, Mika Tiainen, Tuulia Tynkkynen, Najaf Amin, Tanja Zeller, Marian Beekman, Joris Deelen, Ko Willems van Dijk, Tõnu Esko, Jouke-Jan Hottenga, Elisabeth M van Leeuwen, Terho Lehtimäki, Evelin Mihailov, Richard J. Rose, Anton J.M. de Craen, Christian Gieger, Mika Kähönen, Markus Perola, Stefan Blankenberg, Markku J. Savolainen, Aswin Verhoeven, Jorma Viikari, Gonneke Willemsen, Dorret I. Boomsma, Cornelia M. van Duijn, Johan Eriksson, Antti Jula, Marjo-Riitta Järvelin, Jaakko Kaprio, Andres Metspalu, Olli Raitakari, Veikko Salomaa, P. Eline Slagboom, Melanie Waldenberger, Samuli Ripatti, Mika Ala-Korpela

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Regulation of Mitochondrial Respiratory Chain Complex Levels, Organization, and Function by Arginyltransferase 1 by Chunhua Jiang, Balaji T. Moorthy, Devang M. Patel, Akhilesh Kumar, William M. Morgan, Belkis Alfonso, Jingyu Huang, Theodore J. Lampidis, Theodore J. Lampidis, Daniel G. Isom, Daniel G. Isom, Daniel G. Isom, Antoni Barrientos, Antoni Barrientos, Flavia Fontanesi, Fangliang Zhang, Fangliang Zhang

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Evaluation of the Cytotoxic, Anti-Inflammatory, and Immunomodulatory Effects of Withaferin A (WA) against Lipopolysaccharide (LPS)-Induced Inflammation in Immune Cells Derived from... by Abdullah M. Alnuqaydan, Abdulmajeed Almutary, Gh Rasool Bhat, Tanveer Ahmad Mir, Shadil Ibrahim Wani, Mohd Younis Rather, Shabir Ahmad Mir, Bader Alshehri, Sulaiman Alnasser, Faten M. Ali Zainy, Bilal Rah

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Reduced Staphylococcus Abundance Characterizes the Lesional Microbiome of Actinic Keratosis Patients after Field-Directed Therapies by Jan Kehrmann, Fiona Koch, Skrollan Zumdick, Anna Höwner, Lara Best, Lars Masshöfer, Sarah Scharfenberg, Michael Zeschnigk, Jürgen C. Becker, Dirk Schadendorf, Jan Buer, Alexander Roesch

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Whole genome sequencing identifies associations for nonsyndromic sagittal craniosynostosis with the intergenic region of BMP2 and noncoding RNA gene LINC01428 by Anthony M. Musolf, Cristina M. Justice, Zeynep Erdogan-Yildirim, Seppe Goovaerts, Araceli Cuellar, John R. Shaffer, Mary L. Marazita, Peter Claes, Seth M. Weinberg, Jae Li, Craig Senders, Marike Zwienenberg, Emil Simeonov, Radka Kaneva, Tony Roscioli, Lorena Di Pietro, Marta Barba, Wanda Lattanzi, Michael L. Cunningham, Paul A. Romitti, Simeon A. Boyadjiev

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Hypoxia Attenuates Pressure Overload‐Induced Heart Failure by Natali Froese, Malgorzata Szaroszyk, Paolo Galuppo, Joseph R. Visker, Christopher Werlein, Mortimer Korf‐Klingebiel, Dominik Berliner, Marc R. Reboll, Rana Hamouche, Simona Gegel, Yong Wang, Winfried Hofmann, Ming Tang, Robert Geffers, Adam R. Wende, Mark P. Kühnel, Danny D. Jonigk, Georg Hansmann, Kai C. Wollert, E. Dale Abel, Stavros G. Drakos, Johann Bauersachs, Christian Riehle

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Adherence to Opioid Patient Prescriber Agreements at a Safety Net Hospital by Soraira Pacheco, Linh M. T. Nguyen, John M. Halphen, Nikitha N. Samy, Nathaniel R. Wilson, Gregory Sattler, Shane E. Wing, Christine Feng, Rex A. D. Paulino, Pulin Shah, Supriyanka Addimulam, Riddhi Patel, Curtis J. Wray, Joseph A. Arthur, David Hui

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Targeting epigenetic features in clear cell sarcomas based on patient-derived cell lines by Christina Karner, Ines Anders, Djenana Vejzovic, Joanna Szkandera, Susanne Scheipl, Alexander J. A. Deutsch, Larissa Weiss, Klemens Vierlinger, Dagmar Kolb, Stefan Kühberger, Ellen Heitzer, Hansjörg Habisch, Fangrong Zhang, Tobias Madl, Birgit Reininger-Gutmann, Bernadette Liegl-Atzwanger, Beate Rinner

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Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21 by Bhavani S. Sahu, Pedro Rodriguez, Megin E. Nguyen, Ruijun Han, Cheryl Cero, Maria Razzoli, Paolo Piaggi, Lauren J. Laskowski, Mihaela Pavlicev, Louis Muglia, Sushil K. Mahata, Scott O’Grady, John D. McCorvy, Leslie J. Baier, Yuk Y. Sham, Alessandro Bartolomucci

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Extracellular Vesicle Associated miRNAs Regulate Signaling Pathways Involved in COVID-19 Pneumonia and the Progression to Severe Acute Respiratory Corona Virus-2 Syndrome by Agnes S. Meidert, Stefanie Hermann, Florian Brandes, Benedikt Kirchner, Dominik Buschmann, Dominik Buschmann, Jean-Noël Billaud, Matthias Klein, Anja Lindemann, Elisa Aue, Gustav Schelling, Michael W. Pfaffl, Marlene Reithmair

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A missense mutation in Ehd1 associated with defective spermatogenesis and male infertility by Katrin Meindl, Naomi Issler, Naomi Issler, Sara Afonso, Sara Afonso, Alberto Cebrian-Serrano, Alberto Cebrian-Serrano, Alberto Cebrian-Serrano, Karin Müller, Christina Sterner, Helga Othmen, Helga Othmen, Ines Tegtmeier, Ralph Witzgall, Enriko Klootwijk, Benjamin Davies, Benjamin Davies, Robert Kleta, Richard Warth

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Genetic analysis of blood molecular phenotypes reveals common properties in the regulatory networks affecting complex traits by Andrew A. Brown, Juan J. Fernandez-Tajes, Mun-gwan Hong, Caroline A. Brorsson, Robert W. Koivula, David Davtian, Théo Dupuis, Ambra Sartori, Theodora-Dafni Michalettou, Ian M. Forgie, Jonathan Adam, Kristine H. Allin, Robert Caiazzo, Henna Cederberg, Federico De Masi, Petra J. M. Elders, Giuseppe N. Giordano, Mark Haid, Torben Hansen, Tue H. Hansen, Andrew T. Hattersley, Alison J. Heggie, Cédric Howald, Angus G. Jones, Tarja Kokkola, Markku Laakso, Anubha Mahajan, Andrea Mari, Timothy J. McDonald, Donna McEvoy, Miranda Mourby, Petra B. Musholt, Birgitte Nilsson, Francois Pattou, Deborah Penet, Violeta Raverdy, Martin Ridderstråle, Luciana Romano, Femke Rutters, Sapna Sharma, Harriet Teare, Leen ‘t Hart, Konstantinos D. Tsirigos, Jagadish Vangipurapu, Henrik Vestergaard, Søren Brunak, Paul W. Franks, Gary Frost, Harald Grallert, Bernd Jablonka, Mark I. McCarthy, Imre Pavo, Oluf Pedersen, Hartmut Ruetten, Mark Walker, The DIRECT Consortium, Jerzy Adamski, Jochen M. Schwenk, Ewan R. Pearson, Emmanouil T. Dermitzakis, Ana Viñuela

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Expanding the mutation and phenotype spectrum of MYH3-associated skeletal disorders by Sen Zhao, Yuanqiang Zhang, Sigrun Hallgrimsdottir, Yuzhi Zuo, Xiaoxin Li, Dominyka Batkovskyte, Sen Liu, Hillevi Lindelöf, Shengru Wang, Anna Hammarsjö, Yang Yang, Yongyu Ye, Lianlei Wang, Zihui Yan, Jiachen Lin, Chenxi Yu, Zefu Chen, Yuchen Niu, Huizi Wang, Zhi Zhao, Pengfei Liu, Guixing Qiu, Jennifer E. Posey, Zhihong Wu, James R. Lupski, Ieva Micule, Britt-Marie Anderlid, Ulrika Voss, Dennis Sulander, Ekaterina Kuchinskaya, Ann Nordgren, Ola Nilsson, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study, Terry Jianguo Zhang, Giedre Grigelioniene, Nan Wu

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GAA-FGF14 disease: defining its frequency, molecular basis, and 4-aminopyridine response in a large downbeat nystagmus cohortResearch in context by David Pellerin, Felix Heindl, Carlo Wilke, Matt C. Danzi, Andreas Traschütz, Catherine Ashton, Marie-Josée Dicaire, Alexanne Cuillerier, Giulia Del Gobbo, Kym M. Boycott, Jens Claassen, Dan Rujescu, Annette M. Hartmann, Stephan Zuchner, Bernard Brais, Michael Strupp, Matthis Synofzik

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BinomiRare: A robust test for association of a rare genetic variant with a binary outcome for mixed models and any case-control proportion by Tamar Sofer, Jiwon Lee, Nuzulul Kurniansyah, Deepti Jain, Cecelia A. Laurie, Stephanie M. Gogarten, Matthew P. Conomos, Ben Heavner, Yao Hu, Charles Kooperberg, Jeffrey Haessler, Ramachandran S. Vasan, L. Adrienne Cupples, Brandon J. Coombes, Amanda Seyerle, Sina A. Gharib, Han Chen, Jeffrey R. O’Connell, Man Zhang, Daniel J. Gottlieb, Bruce M. Psaty, W.T. Longstreth, Jr., Jerome I. Rotter, Kent D. Taylor, Stephen S. Rich, Xiuqing Guo, Eric Boerwinkle, Alanna C. Morrison, James S. Pankow, Andrew D. Johnson, Nathan Pankratz, Alex P. Reiner, Susan Redline, Nicholas L. Smith, Kenneth M. Rice, Elizabeth D. Schifano

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