Skin fibroblasts of patients with geleophysic dysplasia due to FBN1 mutations have lysosomal inclusions and losartan improves their microfibril deposition defect by Pasquale Piccolo, Valeria Sabatino, Pratibha Mithbaokar, Elena Polishchuk, John Hicks, Roman Polishchuk, Carlos A. Bacino, Nicola Brunetti‐Pierri

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EFFECTS OF DRUG BETAMETHASONE ON HEMATOLOGICAL PARAMETERS OF RATTUS NORVEGICUS (BERKENHOUT 1769) IN VIVO CONDITIONS by Edhem Hasković, Safija Herenda, Amina Herenda, Denis Hasković, Ena Hasković, Amina Selimović

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HNF4α isoforms: the fraternal twin master regulators of liver function by Sarah H. Radi, Kiranmayi Vemuri, Kiranmayi Vemuri, Jose Martinez-Lomeli, Frances M. Sladek

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Generation of the human induced pluripotent stem cell line UKWNLi002-A from dermal fibroblasts of a woman with a heterozygous c.608 C>T (p.Thr203Met) mutation in exon 3 of the nerv... by Thomas Klein, Lisa Henkel, Katharina Klug, Chee Keong Kwok, Eva Klopocki, Nurcan Üçeyler

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Editorial: Chromosome structural variants: Epidemiology, identification and contribution to human diseases by Zirui Dong, Zirui Dong, Zirui Dong, Zirui Dong, Dezso David, Claudia Gonzaga-Jauregui, Cynthia C. Morton, Cynthia C. Morton, Cynthia C. Morton, Cynthia C. Morton, Cynthia C. Morton, Cinthya J. Zepeda-Mendoza

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Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk by Qin Qin Huang, Howard H. F. Tang, Shu Mei Teo, Danny Mok, Scott C. Ritchie, Artika P. Nath, Marta Brozynska, Agus Salim, Andrew Bakshi, Barbara J. Holt, Chiea Chuen Khor, Peter D. Sly, Patrick G. Holt, Kathryn E. Holt, Michael Inouye

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Hypodontia and WNT10A mutation: A case report by Živković-Sandić Marija, Stefanović Neda, Popović Branka, Glišić Branislav

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Generation of an hiPSC-1 knock-in line expressing TY1-tagged MNX1-protein together with mScarlet by Onur Temocin, Dominik Regele, Marc Sathianathan, Christa Überbacher, Markus Hartl, Frank Edenhofer, Dirk Meyer

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Rodent models for psychiatric disorders: problems and promises by Matthew Baker, Sa-Ik Hong, Seungwoo Kang, Doo-Sup Choi

“…Despite significant advancements, many challenges remain after unsuccessful drug development based on rodent models. Recent human genetics show the polygenetic nature of mental disorders, identifying hundreds of allelic variants that confer increased risk. …”
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Genetic Examination of Children Suffering from Cystic Fibrosis by Ediba Saračević, Amira Redžić

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Communication processes about predictive genetic testing within high-risk breast cancer families: a two-phase study design by Chiara L. Blomen, Aliaksandra Pott, Alexander E. Volk, Lars Budäus, Isabell Witzel

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CRISPR/Cas9-mediated editing of ACTB in induced pluripotent stem cells: A model for investigating human ACTB loss-of-function and genetic adaptive responses by Stephanie Binder, Haribaskar Ramachandran, Denise Haslinger, Barbara Hildebrandt, Jochen Dobner, Thomas Haarmann-Stemmann, Andreas Chiocchetti, Andrea Rossi

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The cerebellum contributes to generalized seizures by altering activity in the ventral posteromedial nucleus by Jaclyn Beckinghausen, Joshua Ortiz-Guzman, Tao Lin, Benjamin Bachman, Luis E. Salazar Leon, Yu Liu, Detlef H. Heck, Benjamin R. Arenkiel, Roy V. Sillitoe

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Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling by Mengchen Ye, Kathryn M Lehigh, David D Ginty

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Discriminating protein tags on a dsDNA construct using a Dual Nanopore Device by Swarnadeep Seth, Arthur Rand, Walter Reisner, William B. Dunbar, Robert Sladek, Aniket Bhattacharya

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Effects of Primary Mast Cell Disease on Hemostasis and Erythropoiesis by Holger Seidel, Hans-Jörg Hertfelder, Johannes Oldenburg, Johannes P. Kruppenbacher, Lawrence B. Afrin, Gerhard J. Molderings

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The Effect of Model Directionality on Cell-Type-Specific Differential DNA Methylation Analysis by Elior Rahmani, Brandon Jew, Eran Halperin, Eran Halperin, Eran Halperin, Eran Halperin

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HiCuT: An efficient and low input method to identify protein-directed chromatin interactions. by Satish Sati, Parker Jones, Hali S Kim, Linda A Zhou, Emmanuel Rapp-Reyes, Thomas H Leung

“…HiCuT broadens the capacity for genomic profiling in systems previously unmeasurable, including primary cells, human tissue samples, and rare cell populations, and may be a useful tool for all investigators studying human genetics and personalized epigenomics.…”
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The ambiguous role of mannose-binding lectin (MBL) in human immunity by Kalia Namarta, Singh Jatinder, Kaur Manpreet

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Role of PI3K/AKT pathway in squamous cell carcinoma with an especial focus on head and neck cancers by Soudeh Ghafouri-Fard, Ali Noie Alamdari, Yashar Noee Alamdari, Atefe Abak, Bashdar Mahmud Hussen, Mohammad Taheri, Elena Jamali

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