CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver by Oo, Y, Banz, V, Kavanagh, D, Liaskou, E, Withers, DR, Humphreys, E, Reynolds, G, Lee-Turner, L, Kalia, N, Hubscher, S, Klenerman, P, Eksteen, B, Adams, D

“…Methods: The phenotype and migratory behaviour of human liver-derived Th17 and Tc17 cells were investigated by flow cytometry and chemotaxis and flow-based adhesion assays. …”

CXCR3-dependent recruitment and CCR6-mediated positioning of Th-17 cells in the inflamed liver. by Oo, Y, Banz, V, Kavanagh, D, Liaskou, E, Withers, DR, Humphreys, E, Reynolds, G, Lee-Turner, L, Kalia, N, Hubscher, S, Klenerman, P, Eksteen, B, Adams, D

“…METHODS: The phenotype and migratory behaviour of human liver-derived Th17 and Tc17 cells were investigated by flow cytometry and chemotaxis and flow-based adhesion assays. …”

Structural biology of an organ by David W. Taylor

“…Su et al.1 use a build-and-retrieve approach to both identify and determine structures of ten macromolecular machines in the human liver. The authors’ method will launch researchers forward in understanding the structural biology of the cell (or organ).…”
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SYNTHESIS OF CYCLOPENTANE SPIROHYDANTOINS BY ALDOL CYCLIZATIONS - AN APPROACH TO HIGHLY SUBSTITUTED ALPHA-CYCLOPENTANE AMINO-ACIDS by Fairbanks, A, Elliott, R, Smith, C, Hui, A, Way, G, Storer, R, Taylor, H, Watkin, D, Winchester, B, Fleet, G

“…The effects of some of the compounds on human liver-glycosidases are described. © 1993.…”

Isolated Primary Hydatid Disease of Omentum; Report of a Case and Review of the Literature by Ali Ghafouri, Shirzad Nasiri, Abolfazl Shojaee Far, Mohammad Reza Mobayen, Mehdi Tahamtan, Mohammad Nazari, Zeinab Gharib Doost

“…Hydatid disease, most commonly caused by the larval stage ofEchinococcus granulosus, affects mainly human liver andlung, and rarely other parts of the body. …”
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How possible was Prometheus' punishment? by Ryan Robinson, Sarah Gent

“…A simple model is constructed that incorporates the eating habits of eagles – how much food they eat in a day – as well as the natural regeneration time of a human liver. Our calculations have shown that if Prometheus' liver was the only food source of the eagle (300g consumed per day), it would take approximately 2 days for complete regeneration. …”
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Trematodoses of the liver, bile ducts and pancreatic ducts (invasions caused by hepatic flukes) by S. B. Chuelov, A. L. Rossina

“…The paper summarizes the information currently available in the literature on the etiology, life cycles, epidemiology, pathogenesis, pathomorphology, clinical manifestations, diagnosis, etiotropic therapy, and prevention of human liver, bile ducts and pancreatic ducts trematodiases: fascioliasis, opisthorchiasis, clonorchiais, metorchiasis, pseudamphistomiasis, amphimeriasis, dicrocoeliasis, eurytremiasis.…”
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SYNTHESIS FROM D-MANNOSE OF 1,4-DIDEOXY-1,4-IMINO-L-RIBITOL AND OF THE ALPHA-MANNOSIDASE INHIBITOR 1,4-DIDEOXY-1,4-IMINO-D-TALITOL by Fleet, G, Son, J, Green, D, Dibello, I, Winchester, B

“…The syntheses of 1,4-dideoxy-l,4-imino-L-ribitol and of 1,4-dideoxy-l,4-imino-D-talitol from D-mannose are described. 1,4-Dideoxy-l,4-imino-D-talitol is a specific and competitive inhibitor of human liver α-mannosidase in vitro and also blocks the lysosomal catabolism of asparigine-linked glycans of glycoproteins in vivo. © 1988.…”

Identification of the effect of cisplatin on the transcriptome of human hepatocellular carcinoma cell lines by GUO Xin, JI Mengdie, WANG Qi, LI Xueyuan, CHEN Yang

“…Objective To investigate the effect of cisplatin treatment on the transcriptional level of human liver cancer cells by conducting transcriptome sequencing analysis after treating human liver cancer cell lines with different concentrations of cisplatin (CDDP). …”
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Extracellular Matrix Optimization for Enhanced Physiological Relevance in Hepatic Tissue-Chips by Abdul Rahim Chethikkattuveli Salih, Kinam Hyun, Arun Asif, Afaque Manzoor Soomro, Hafiz Muhammad Umer Farooqi, Young Su Kim, Kyung Hwan Kim, Jae Wook Lee, Dongeun Huh, Kyung Hyun Choi

“…The recent emergence of hepatic microphysiological systems (MPS) provide the basic physiological emulation of the human liver for drug screening. However, engineering microfluidic devices with standardized surface coatings of ECM may improve MPS-based organ-specific emulation for improved drug screening. …”
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Antibacterial and Antiproliferative Activities of <i>Azadirachta indica</i> Leaf Extract and Its Effect on Oil-in-Water Food Emulsion Stability by Manel Ouerfelli, Isidoro Metón, Idoia Codina-Torrella, María Pilar Almajano

“…The present study aims to identify and quantify the phenolic compounds of <i>Azadirachta indica</i> leaf extract using HPLC-MS and to evaluate the antioxidant, antibacterial (against different Gram-positive and negative bacteria) and in vitro anti-proliferative activities of this extract (against breast, human liver and cervix adenocarcinoma-derived cells). …”
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Machine vision-based Statistical texture analysis techniques for characterization of liver tissues using CT images by Mehrun Nisa, Saeed Ahmad Buzdar, Muhammad Arshad Javid, Muhamamd Saeed Ahmad, Ayesha Ikhlaq, Sadia Riaz

“… Objective: To characterize human liver tissues by demonstrating the ability of machine vision, and to propose a new auto-generated report based on texture analysis that may work with co-occurrence matrix statistics. …”
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The presence of Helicobacter pylori in the liver depends on the Th1, Th17 and Treg cytokine profile of the patient by Luciana Diniz Silva, Andreia Maria Camargos Rocha, Gifone Aguiar Rocha, Sílvia Beleza de Moura, Márcia Maria Negreiros Pinto Rocha, Renato Dani, Fabrício Freire de Melo, Juliana Becattini Guerra, Lúcia Porto Fonseca de Castro, Guilherme Santiago Mendes, Teresa Cristina de Abreu Ferrari, Agnaldo Soares Lima, Dulciene Maria Magalhães Queiroz

“…The hypothesis that Helicobactermight be a risk factor for human liver diseases has arisen after the detection of Helicobacter DNA in hepatic tissue of patients with hepatobiliary diseases. …”
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Contribution of Resident Stem Cells to Liver and Biliary Tree Regeneration in Human Diseases by Diletta Overi, Guido Carpino, Vincenzo Cardinale, Antonio Franchitto, Samira Safarikia, Paolo Onori, Domenico Alvaro, Eugenio Gaudio

“…The present review summarizes the contribution of stem/progenitor cell niches in human liver diseases, underlining mechanisms of activation and clinical implications, including fibrogenesis and disease progression.…”
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Nicotinamide Adenine Dinucleotide Metabolome Is Functionally Depressed in Patients Undergoing Liver Transplantation for Alcohol‐Related Liver Disease by Richard Parker, Mark S. Schmidt, Owen Cain, Bridget Gunson, Charles Brenner

“…NAD‐targeted quantitative metabolomic analysis of liver tissue was performed by liquid chromatography–tandem mass spectrometry. Seventy‐two human liver specimens were analyzed, including 43 with ArLD. …”
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Picomolar inhibitor of reverse transcriptase featuring significantly improved metabolic stability by Ya-Li Sang, Christophe Pannecouque, Erik De Clercq, Shuai Wang, Fen-Er Chen

“…Considering the undesirable metabolic stability of our recently identified NNRTI 5 (t1/2 = 96 min) in human liver microsomes, we directed our efforts to improve its metabolic stability by introducing a new favorable hydroxymethyl side chain to the C-5 position of pyrimidine. …”
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In Vitro Metabolic Fate of the Synthetic Cannabinoid Receptor Agonists QMPSB and QMPCB (SGT-11) Including Isozyme Mapping and Esterase Activity by Matthias J. Richter, Lea Wagmann, Tanja M. Gampfer, Simon D. Brandt, Markus R. Meyer

“…The presented study aimed to identify the in vitro phase I/II metabolites of QMPSB and QMPCB and to study the contribution of different monooxygenases and human carboxylesterases by using pooled human liver S9 fraction (pHLS9), recombinant human monooxygenases, three recombinant human carboxylesterases, and pooled human liver microsomes. …”
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Progesterone Metabolism by Human and Rat Hepatic and Intestinal Tissue by Zoe Coombes, Katie Plant, Cristina Freire, Abdul W. Basit, Philip Butler, R. Steven Conlan, Deyarina Gonzalez

“…The rate of progesterone depletion was found to be significantly reduced by AKR1C, 1D1 and 1B1 in human liver and by AKR1B1 in human intestine. The inhibition of AOX also caused a significant reduction in progesterone degradation in human liver, whereas no change was observed in the presence of an XAO inhibitor. …”
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Kallistatin, a new and reliable biomarker for the diagnosis of liver cirrhosis by Zhiyun Cheng, Yinghui Lv, Suqiu Pang, Ruyu Bai, Mingxi Wang, Shuyu Lin, Tianwen Xu, Duncan Spalding, Nagy Habib, Ruian Xu

“…However, its relationship to human liver disease remains unclear. The purpose of this study was to explore the relationship between serum kallistatin and clinical evidence of both cirrhosis and hepatocellular carcinoma (HCC), and to determine if serum kallistatin levels could be used as a diagnostic indicator of hepatic health status, especially human liver cirrhosis (LC). …”
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Feasibility of absolute quantification for 31P MRS at 7 T by Purvis, LAB, Valkovic, L, Robson, MD, Rodgers, CT

“…Using an 18‐mM phosphate phantom and simplified normalization, human liver phosphate metabolite concentrations were successfully quantified at 7 T.…”