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14961
Synergies of Human Umbilical Vein Endothelial Cell-Laden Calcium Silicate-Activated Gelatin Methacrylate for Accelerating 3D Human Dental Pulp Stem Cell Differentiation for Endodon...
Published 2021-09-01“…In this study, we fabricated cell blocks with human dental pulp stem cells (hDPSCs)-laden alginate/fish gelatin hydrogels (Alg/FGel) at the center of the cell block and human umbilical vascular endothelial cells (HUVEC)-laden Si ion-infused fish gelatin methacrylate (FGelMa) at the periphery of the cell block. …”
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Article -
14962
Platelet lysate for expansion or osteogenic differentiation of bone marrow mesenchymal stem cells for 3D tissue constructs
Published 2023-12-01“…Differentiation capacity of the BMSCs expanded in the presence of the different supplements was evaluated in 3D type I collagen hydrogels. Furthermore, the effects of the supplements on the process of differentiation were analyzed by using qPCR and histological staining. …”
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Article -
14963
Optimization of Mechanosensitive Cross-Talk between Matrix Stiffness and Protein Density: Independent Matrix Properties Regulate Spreading Dynamics of Myocytes
Published 2022-07-01“…For this, C2C12 myocytes were monitored on L-DOPA functionalized hydrogels of 22 different elasticity and fibronectin density compositions. …”
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Article -
14964
Effect of Local Basic Fibroblast Growth Factor and Vascular Endothelial Growth Factor on Subcutaneously Allotransplanted Ovarian Tissue in Ovariectomized Mice.
Published 2015-01-01“…Ovarian tissues encapsulated by fibrin hydrogels were transplanted subcutaneously into recipient mice, in which ovarian hormonal cyclicity was absent. …”
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Article -
14965
A review on drought stress in plants: Implications, mitigation and the role of plant growth promoting rhizobacteria
Published 2021-09-01“…Employment of nanoparticles, film farming, use of drought resistant plant varieties, super-absorbent hydrogels, and biochar are some techniques used to ameliorate drought stress. …”
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Article -
14966
Treatment of Peripheral Artery Disease Using Injectable Biomaterials and Drug-Coated Balloons: Safety and Efficacy Perspective
Published 2023-06-01“…We conducted a thorough review of the literature on the use and efficacy of biomaterials (BMs) and drug-coated balloons (DCBs). These BMs included hydrogels, collagen scaffolds, and nanoparticles. These BMs could be used alone or in combination with growth factors, stem cells, or gene therapy. …”
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Article -
14967
Exploiting three-dimensional human hepatic constructs to investigate the impact of rs174537 on fatty acid metabolism.
Published 2022-01-01“…Primary human hepatocytes cultured in 3D hydrogels were characterized for their capacity to represent basic lipid processing functions, including lipid esterification, de novo lipogenesis, and cholesterol efflux. …”
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Article -
14968
Natural Polymeric Scaffolds in Bone Regeneration
Published 2020-05-01“…Their assembly and further engineering give rise to a wide plethora of advanced supporting materials, accounting for systems based on hydrogels or scaffolds with either fibrous or porous architecture. …”
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Article -
14969
Mechanoregulation of MSC spheroid immunomodulation
Published 2024-03-01“…We exposed MSC spheroids, entrapped in alginate hydrogels, to three cyclic compressive regimes with varying stress (L) magnitudes (i.e., 5 and 10 kPa) and hold (H) durations (i.e., 30 and 250 s) L5H30, L10H30, and L10H250. …”
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Article -
14970
Controlled drug delivery systems for oral cancer treatment--current status and future perspectives
Published 2020“…This review confers current knowledge on the diverse drug delivery methods, potential carriers (e.g., polymeric, inorganic, and combinational nanoparticles; nanolipids; hydrogels; exosomes) and anticancer targeted approaches for oral squamous cell carcinoma treatment, with an emphasis on their clinical relevance in the era of precision medicine, circadian chronobiology and patient-centred health care. ©2019 Keywords: oral, head and neck squamous cell carcinoma; targeted therapies; drug delivery systems; nanoparticles; controlled drug delivery; circadian clock; chronotherapy; precision medicine…”
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Article -
14971
Fracture mechanics in the semigrand canonical ensemble
Published 2022“…While counter-intuitive on first sight, this soft-tough paradigm can explain a number of experimental observations, including toughening of brittle solids by deformable polymers or organics, such as gas shale, nacre, stress-induced transformational toughening mechanisms in ceramics, and toughening of sparse elastic networks in hydrogels, to name a few.…”
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Thesis -
14972
Computational Investigation of the Catalytic and Structural Roles of Metals in Metalloenzymes
Published 2022“…In this thesis, we also provide computational evidence for the mechanical interlocking of proteins in hydrogels, a phenomenon that is difficult to visualize experimentally. …”
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Thesis -
14973
Property determinants of dextran:polyethylene glycol adhesive sealants
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Thesis -
14974
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14975
Second-order theory of the shearing of soft beams
Published 2020“…In the era of new advanced technologies, highly artificial compliant devices that are made of soft materials are continually being invented and manufactured by these soft materials are generally consists of silicone rubber, hydrogels and other soft biological materials. However, these soft materials have the possibility of undergoing infinite deformation because they have the unique properties of texture softness and the characteristics of flexibility and adaptability regardless of how small the item is being manufactured. …”
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Final Year Project (FYP) -
14976
Extraction of collagen from bullfrog skin
Published 2020“…The extracted collagen can be used to fabricate films, scaffolds or hydrogels where its mechanical properties can be tuned for its required applications such as wound healing and tissue engineering. …”
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Final Year Project (FYP) -
14977
Extrusion-based 3D bioprinting of the cornea using decellularized extracellular matrix
Published 2024“…Additionally, the establishment of an effective crosslinking method is explored to ensure the durability of the resulting hydrogels. Unlike traditional treatments such as corneal transplants or Keratoprosthesis, 3D bioprinted corneas have the potential to trigger the full recovery of the diseased cornea, offering a comprehensive solution for patients. …”
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Final Year Project (FYP) -
14978
Simulation of the tensile loading of a cylindrical gel
Published 2013“…Prior to that, a physically possible range for the elastic constants were obtained as hydrogels have no evidence of undergoing negative strain and hence a negative Poisson’s ratio. …”
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Final Year Project (FYP) -
14979
A 3D microtumour system that faithfully represents ovarian cancer minimal residual disease
Published 2023“…</p> <p><strong>Methods</strong> A microfluidic technique was implemented to construct 3D microtumours, in which tumour cells, either by themselves or with fibroblasts, were encapsulated in viscous hydrogels. The 3D microtumours were analysed for their response to first-line chemotherapeutics and characterised through RNA-Seq, by comparing them to both 2D cultures and clinical samples.…”
Internet publication -
14980
Impact of large, periodic deformations on flow and transport in soft porous media
Published 2023“…Soft porous media, such as soils, hydrogels, or soft biological tissues, are characterised by a strong coupling between deformation and fluid flow due to complex rearrangements of the pore space. …”
Thesis