Manipulating Conjugation in electronic polymers and graphitic materials: chemosensors, precursor routes, and self-assembly by Weis, Jonathan G. (Jonathan Garrett)

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Topographic Guidance in Melt-Electrowritten Tubular Scaffolds Enhances Engineered Kidney Tubule Performance by Anne Metje van Genderen, Katja Jansen, Marleen Kristen, Marleen Kristen, Joost van Duijn, Joost van Duijn, Yang Li, Yang Li, Carl C. L. Schuurmans, Carl C. L. Schuurmans, Jos Malda, Jos Malda, Jos Malda, Tina Vermonden, Tina Vermonden, Jitske Jansen, Rosalinde Masereeuw, Rosalinde Masereeuw, Miguel Castilho, Miguel Castilho, Miguel Castilho

“…Introduction: To date, tubular tissue engineering relies on large, non-porous tubular scaffolds (Ø > 2 mm) for mechanical self-support, or smaller (Ø 150–500 μm) tubes within bulk hydrogels for studying renal transport phenomena. To advance the engineering of kidney tubules for future implantation, constructs should be both self-supportive and yet small-sized and highly porous. …”
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Application of Fibrin Associated with Photobiomodulation as a Promising Strategy to Improve Regeneration in Tissue Engineering: A Systematic Review by Carlos Henrique Bertoni Reis, Daniela Vieira Buchaim, Adriana de Cássia Ortiz, Simone Ortiz Moura Fideles, Jefferson Aparecido Dias, Maria Angelica Miglino, Daniel de Bortoli Teixeira, Eliana de Souza Bastos Mazuqueli Pereira, Marcelo Rodrigues da Cunha, Rogerio Leone Buchaim

“…In its diversity of forms of application and constitution, there are platelet-rich fibrin (PRF), Leukocyte- and platelet-rich fibrin (L-PRF), fibrin glue or fibrin sealant, and hydrogels. In order to increase fibrin properties, adjuvant therapies can be combined to favor tissue repair, such as photobiomodulation (PBM), by low-level laser therapy (LLLT) or LEDs (Light Emitting Diode). …”
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Polydatin attenuates tubulointerstitial fibrosis in diabetic kidney disease by inhibiting YAP expression and nuclear translocation by Manlin He, Lan Feng, Yang Chen, Bin Gao, Yiwei Du, Lu Zhou, Fei Li, Fei Li, Hongbao Liu

“…Therefore, this study intends to solve the following two problems: 1) To construct an in vitro system of polyacrylamide hydrogels (PA gels) based on the true stiffness of kidneys in healthy and DKD rats, and observe the effect of PD on pathological matrix stiffness-induced YAP expression in renal fibroblasts; 2) Compared with verteporfin (VP), a pharmacological inhibitor of YAP, to explore whether the therapeutic effect of PD on DKD in vivo model is related to the regulation of YAP. …”
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Recombinant Laminin-511 Fragment (iMatrix-511) Coating Supports Maintenance of Human Nucleus Pulposus Progenitor Cells In Vitro by Hazuki Soma, Daisuke Sakai, Yoshihiko Nakamura, Shota Tamagawa, Takayuki Warita, Jordy Schol, Erika Matsushita, Mitsuru Naiki, Masato Sato, Masahiko Watanabe

“…To gauge their regenerative potential, we examined their extracellular matrix (ECM) production capacity (intracellular type II collagen (Col2) and proteoglycans (PG)) and their ability to form spherical colonies within methylcellulose hydrogels. Lami-coat significantly enhanced cell proliferation rates and increased Tie2 expression, resulting in a 7.9-fold increase in Tie2-expressing cell yields. …”
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An Overview of Biopolymeric Electrospun Nanofibers Based on Polysaccharides for Wound Healing Management by Andreea-Teodora Iacob, Maria Drăgan, Oana-Maria Ionescu, Lenuța Profire, Anton Ficai, Ecaterina Andronescu, Luminița Georgeta Confederat, Dan Lupașcu

“…Over the past several years, various types of wound dressings including hydrogels, hydrocolloids, films, foams, sponges, and micro/nanofibers have been formulated, and among them, the electrospun nanofibrous mats received an increased interest from researchers due to the numerous advantages and their intrinsic properties. …”
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Mechanosensation mediates volume adaptation of cardiac cells and spheroids in 3D by Ian L. Chin, Sebastian E. Amos, Ji Hoon Jeong, Livia Hool, Yongsung Hwang, Yu Suk Choi

“…In this study, H9C2 cardiac-derived myoblasts were encapsulated as individual cells and as cell spheroids within stiffness gradient gelatin methacryloyl (GelMA) hydrogels to investigate individual and collective cardiac cell mechanosensation in 3D. …”
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Functional differences in human aortic valve interstitial cells from patients with varying calcific aortic valve disease by Robin Tuscher, Alex Khang, Toni M. West, Chiara Camillo, Giovanni Ferrari, Michael S. Sacks

“…To accomplish this, we characterized AVIC basal tonus behaviors from diseased human AV tissues embedded in 3D hydrogels. Established methods were utilized to track AVIC-induced gel displacements and shape changes after the application of Cytochalasin D (an actin polymerization inhibitor) to depolymerize the AVIC stress fibers. …”
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Toward a Physiologically Relevant 3D Helicoidal-Oriented Cardiac Model: Simultaneous Application of Mechanical Stimulation and Surface Topography by Fatemeh Navaee, Philippe Renaud, Niccolò Piacentini, Mathilde Durand, Dara Zaman Bayat, Diane Ledroit, Sarah Heub, Stephanie Boder-Pasche, Alexander Kleger, Thomas Braschler, Gilles Weder

“…For this purpose, uniaxial mechanical stretching of dECM-fibrin hydrogels was performed on pre-aligned 3D cultures of cardiac cells. …”
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Imiquimod-Loaded Chitosan-Decorated Di-Block and Tri-Block Polymeric Nanoparticles Loaded In Situ Gel for the Management of Cervical Cancer by Aliyah Almomen, Mohamed Badran, Adel Ali Alhowyan, Musaed Alkholief, Aws Alshamsan

“…The NPs were then incorporated into poloxamer hydrogels. The NPs’ size and morphology, encapsulation efficiency (EE), in vitro drug release, gel characterization, ex vivo drug permeation, and in vitro safety and efficacy were characterized. …”
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Visualizing the bibliometrics of the inflammatory mechanisms in intervertebral disc degeneration by Nan Wang, Weihao Rong, Yimin Xie, Shuang Chen, Zhipeng Xi, Rongrong Deng

“…In terms of treatment, alongside traditional monomer, drug, and compound therapies for IVDD, research is increasingly concentrating on stem cell therapy, exosomes, hydrogels, and scaffolds. Conclusion: This bibliometric analysis of research on inflammatory mechanisms in IVDD provides insights into the current status, hotspots, and potential future trends. …”
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Bioinspired squid peptides─a tale of curiosity-driven research leading to unforeseen biomedical applications by Sun, Yue, Hiew, Shu Hui, Miserez, Ali

“…One example includes short peptide hydrogels that self-assemble entirely under aqueous conditions and simultaneously encapsulate large macromolecules during the gelation process. …”
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Development of a novel and economical agar-based non-adherent three-dimensional culture method for enrichment of cancer stem-like cells by Weijie Gao, Dinglan Wu, Yuliang Wang, Zhu Wang, Chang Zou, Yong Dai, Chi-Fai Ng, Jeremy Yuen-Chun Teoh, Franky Leung Chan

“…Different non-adhesive coating agents, such as poly-2-hydroxyethyl methacrylate (poly-HEMA) and synthetic hydrogels, have been used in this non-adherent 3D culture. …”
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Gelatin Nanoparticles-HPMC Hybrid System for Effective Ocular Topical Administration of Antihypertensive Agents by Sergio Esteban-Pérez, Vanessa Andrés-Guerrero, José Javier López-Cano, Irene Molina-Martínez, Rocio Herrero-Vanrell, Irene Bravo-Osuna

“…For several years, different strategies based on nanotechnology, hydrogels or implants have been evaluated. Nowadays, the tolerance of ophthalmic preparations has become a critical issue and it is essential to the use of well tolerated excipients. …”
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Stable Isotope-Resolved Metabolomics Shows Metabolic Resistance to Anti-Cancer Selenite in 3D Spheroids versus 2D Cell Cultures by Teresa W.-M. Fan, Salim S. El-Amouri, Jessica K. A. Macedo, Qing Jun Wang, Huan Song, Teresa Cassel, Andrew N. Lane

“…There are several three-dimensional (3D) cell culture systems such as Matrigel, hydrogels, micropatterned plates, and hanging drop that overcome these drawbacks but they suffer from technical challenges including long spheroid formation times, difficult handling for high throughput assays, and/or matrix contamination for metabolic studies. …”
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Cell-Seeded Biomaterial Scaffolds: The Urgent Need for Unanswered Accelerated Angiogenesis by Shokrani H, Shokrani A, Sajadi SM, Seidi F, Mashhadzadeh AH, Rabiee N, Saeb MR, Aminabhavi T, Webster TJ

“…To address the aforementioned need, this review article summarizes a variety of natural and synthetic scaffolds including hydrogels that support angiogenesis. Furthermore, we review a variety of cell sources utilized for cell seeding and influential factors used for angiogenesis with a concentrated focus on biomechanical factors, with unique stimulatory factors. …”
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Eliminating Heavy Metals from Water with NanoSheet Minerals as Adsorbents by Shaoxian Song

“…Nano-sheet minerals are used as adsorbents in the form of three-dimension hydrogels. They are featured by the huge specific surface area and high adsorption efficiency. …”
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Eliminating Heavy Metals from Water with Nano-Sheet Minerals as Adsorbents by Shaoxian Song

“…<br />Nano-sheet minerals are used as adsorbents in the form of three-dimension hydrogels. They are featured by the huge specific surface area and high adsorption efficiency. …”
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Improved cartilage regeneration by implantation of acellular biomaterials after bone marrow stimulation: a systematic review and meta-analysis of animal studies by Michiel W. Pot, Veronica K. Gonzales, Pieter Buma, Joanna IntHout, Toin H. van Kuppevelt, Rob B.M. de Vries, Willeke F. Daamen

“…No significant differences were found between biomaterials from natural or synthetic origin or between scaffolds, hydrogels and blends. No noticeable differences were found in outcome between animal models. …”
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Chemomechanics at the cell-material interface : measurements and implications of forced molecular unbinding by Lee, Sunyoung, Ph. D. Massachusetts Institute of Technology

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