Association between pre-existing cardiovascular disease, mortality and cardiovascular outcomes in hospitalised patients with COVID-19 by Hari P. Sritharan, Hari P. Sritharan, Kunwardeep S. Bhatia, William van Gaal, William van Gaal, Leonard Kritharides, Leonard Kritharides, Clara K. Chow, Clara K. Chow, Ravinay Bhindi, Ravinay Bhindi

“…Apart from age, other cardiovascular risk factors such as diabetes, hypercholesterolemia and hypertension had no significant impact on mortality, clinical cardiovascular complications or myocardial injury.ConclusionsPre-existing cardiovascular disease is associated with significantly higher mortality in patients hospitalised with COVID-19. …”
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‘Saba’ banana (Musa acuminata x balbisiana BBB Group) peel pectin supplementation improves biomarkers of obesity and associated blood lipid disorders in obese hypercholesterolemic... by Paul Alteo A. Bagabaldo, Liezl M. Atienza, Katherine Ann T. Castillo-Israel, Maria Amelita C. Estacio, Prince Joseph V. Gaban, Jonna Rose C. Maniwang, Roxanne P. Gapasin, Abbie Glenn M. Estribillo, Rohani B. Cena-Navarro

“…ICR male mice were induced with obesity and hypercholesterolemia using 45% high fat diet (HFD) for three weeks. …”
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Longitudinal Trends in Severe Dyslipidemia in the Czech Population: The Czech MONICA and Czech Post-MONICA Study by Renata Cífková, Jan Bruthans, Peter Wohlfahrt, Alena Hrubeš Krajčoviechová, Pavel Šulc, Marie Jozífová, Lenka Eremiášová, Jan Pudil, Aleš Linhart, Jiří Widimský, Jan Filipovský, Otto Mayer, Rudolf Poledne, Petr Stávek, Věra Lánská, Larysa Strilchuk

“…<b>Background:</b> Severe hypercholesterolemia is associated with an increase in the risk of developing atherosclerotic cardiovascular disease. …”
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Correlation between Snoring and 10-year Risk of Atherosclerotic Cardiovascular Disease in Middle-aged and Elderly Population by LUO Yuanxin, PENG Derong, ZHANG Lin, LIU Haiying, TAN Jun

“…Further analysis of the relationship between snoring and ASCVD risk factors showed that severe snoring was a risk factor for hypertriglyceridemia, hypercholesterolemia, hyper-low-density lipoproteinemia and hypo-high-density lipoproteinemia, and moderate snoring was a risk factor for hyper-low-density lipoproteinemia and hypo-high-density lipoproteinemia compared with no snoring (P&lt;0.05) . …”
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Predictors of cardiovascular complications in patients with arterial hypertension and comorbid pathology by Ilkhom T. Murkamilov, Victor V. Fomin, Furkat A. Yusupov, Ibragim S. Sabirov

“…In patients with hypertension and comorbid pathology, the most common abnormalities were an increased level of LDL cholesterol (58%), a decreased level of HDL cholesterol (51.8%), hypercholesterolemia (54.3%), hypertriglyceridemia (43.8%) and tachycardia (40.7%). …”
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Characterization of Retinal Drusen in Subjects at High Genetic Risk of Developing Sporadic Alzheimer’s Disease: An Exploratory Analysis by Inés López-Cuenca, Elena Salobrar-García, Inés Gil-Salgado, Lidia Sánchez-Puebla, Lorena Elvira-Hurtado, José A. Fernández-Albarral, Federico Ramírez-Toraño, Ana Barabash, Jaisalmer de Frutos-Lucas, Juan J. Salazar, José M. Ramírez, Ana I. Ramírez, Rosa de Hoz

“…We analyzed and characterized retinal drusen by optical coherence tomography (OCT) in subjects, classifying them by their AD FH (FH- or FH+) and their allelic characterization of ApoE ɛ4 (ApoE ɛ4- or ApoE ɛ4+) and considering cardiovascular risk factors (hypercholesterolemia, hypertension, and diabetes mellitus). …”
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Cardiovascular therapy in patients hospitalized for elective large joint arthroplasty: real-world practice review by Elena A. Okisheva, Olga Iu. Mironova, Maria D. Madoyan, Svetlana E. Fidanyan, Aida I. Semenova, Alexandr S. Panferov, Andrey V. Strokov, Ivan N. Tarabarko, Andrey V. Garkavi, Alexey V. Lychagin, Victor V. Fomin

“…Most patients with hypercholesterolemia did not receive statins with no rationale for not prescribing this class of drugs. …”
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Outpatient Register of Patients with Acute Myocardial Infarction: Assessment of the Hypertension Impact on Long-term Prognosis by D. P. Sichinava, E. P. Kalaydzhyan, N. P. Kutishenko, S. Yu. Martsevich

“…There were no significant differences between the groups of patients with and without AH in the history of cerebral stroke, AMI, arrhythmia by AF type, diabetes mellitus and obesity, except for angina of tension (18.6% and 2.4%, respectively) and hypercholesterolemia (37.3% and 11.9%, respectively), p&lt;0.05 for both. …”
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Human Hepatocyte Nuclear Factors (HNF1 and LXRb) Regulate CYP7A1 in HIV-Infected Black South African Women with Gallstone Disease: A Preliminary Study by Suman Mewa Kinoo, Pragalathan Naidoo, Bhugwan Singh, Anil Chuturgoon, Savania Nagiah

“…HIV-infected patients on combination antiretroviral therapy (cART) are more prone to hypercholesterolemia. Bile acid synthesis is initiated by cholesterol 7-alpha hydroxylase (CYP7A1) and regulated by hepatocyte nuclear factors (HNF1α, HNF4α, and LXRb). …”
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Single and Combined Associations of Plasma and Urine Essential Trace Elements (Zn, Cu, Se, and Mn) with Cardiovascular Risk Factors in a Mediterranean Population by Rocío Barragán, Cristina Sánchez-González, Pilar Aranda, José V. Sorlí, Eva M. Asensio, Olga Portolés, Carolina Ortega-Azorín, Laura V. Villamil, Oscar Coltell, Juan Llopis, Lorenzo Rivas-García, Dolores Corella

“…Moreover, in the joint exposure analysis using quantile g-computation and TERS, the combined plasma levels of Zn, Cu, Se (directly), and Mn (inversely) were strongly associated with hypercholesterolemia (OR: 2.03; 95%CI: 1.37–2.99; <i>p</i> < 0.001 per quartile increase in the g-computation approach). …”
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Association of Cardiovascular Disease and Long-Term Exposure to Fine Particulate Matter (PM_2.5) in the Southeastern United States by R. Burciaga Valdez, Mohammad Z. Al-Hamdan, Mohammad Tabatabai, Darryl B. Hood, Wansoo Im, Derek Wilus, Amruta Nori-Sarma, Aramandla Ramesh, Macarius M. Donneyong, Michael A. Langston, Charles P. Mouton, Paul D. Juárez

“…The SCCS participants with medical histories of hypertension, hypercholesterolemia, and smoking had, overall, 385 percent higher odds of reported CVD than those without these clinical risk factors. …”
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Association of obesity with the development of end stage renal disease in IgA nephropathy patients by Siqing Wang, Siqing Wang, Aiya Qin, Aiya Qin, Lingqiu Dong, Lingqiu Dong, Jiaxing Tan, Jiaxing Tan, Xiaoyuan Zhou, Wei Qin, Wei Qin

“…In addition, patients with obesity tended to have higher risk of metabolic disorders, such as hyperuricemia (64.4% vs 37%, p&lt;0.001), hypertriglyceridemia (71.3% vs 32.5%, p&lt;0.001) and hypercholesterolemia (46.5% vs 35.6%, p=0.036). It was observed that obesity patients had higher rate of unhealthy behaviors, such as smoking (27.7% vs 16.4%, p=0.006) and alcohol drinking (29.7% vs 19.9%, p=0.027). …”
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Red Blood Cell Distribution Width: A Risk Factor for Prognosis in Patients with Ischemic Cardiomyopathy after Percutaneous Coronary Intervention by Biyang Zhang, Yinxiao Xu, Xin Huang, Tienan Sun, Meishi Ma, Zheng Chen, Yujie Zhou

“…Patients with hypercholesterolemia or without anemia also had a higher risk of MACE. …”
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A Rare Entity: Primary Pulmonary Meningioma by Aynur BAŞ, Elgün VALIYEV, Nur DILVIN ÖZKAN, İsmail TOMBUL, Selcen YONAT, Muhammet SAYAN, İsmail Cüneyt KURUL

“…His medical history included 30 pack-year smoking history, hypertension, arrhythmia, and hypercholesterolemia. In 2015, a well-circumscribed lesion 10 mm in diameter had been detected in the subpleural area of the left lower lobe with thorax CT. …”
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Association of diabetes and exposure to fine particulate matter (PM2.5) in the Southeastern United States by R. Burciaga Valdez, Mohammad Tabatabai, Mohammad Z. Al-Hamdan, Derek Wilus, Darryl B. Hood, Wansoo Im, Amruta Nori-Sarma, Aramandla Ramesh, Macarius M. Donneyong, Michael A. Langston, Charles P. Mouton, Paul D. Juárez

“…Participants with medical histories of hypertension, hypercholesterolemia, and smoking had an overall 384% higher odds of reported diabetes than those without these clinical risk factors. …”
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Influence of Demographic and Lifestyle Variables on Plasma Magnesium Concentrations and Their Associations with Cardiovascular Risk Factors in a Mediterranean Population by Rocío Barragán, Juan Llopis, Olga Portolés, Jose V. Sorlí, Oscar Coltell, Lorenzo Rivas-García, Eva M. Asensio, Carolina Ortega-Azorín, Dolores Corella, Cristina Sánchez-González

“…In conclusion, our results contribute to increasing the evidence gathered by numerous studies on the inverse association between hypomagnesemia and type-2 diabetes, as well as to the observation, previously reported in some studies, of a direct association with hypercholesterolemia. This paradoxical link should be deeply investigated in further studies.…”
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Drug Survival of Upadacitinib and Predicting Factors of Discontinuation in Adult Patients Affected by Moderate-to-Severe Atopic Dermatitis: An Italian Multicenter Analysis by Elena Pezzolo, Michela Ortoncelli, Silvia Mariel Ferrucci, Mario Bruno Guanti, Donatella Schena, Maddalena Napolitano, Mariateresa Rossi, Caterina Foti, Domenico D’Amico, Giuseppe Fabrizio Amoruso, Pietro Morrone, Simone Ribero, Francesca Barei, Matteo Biagi, Enrico Pascucci, Cataldo Patruno, Piergiacomo Calzavara Pinton, Paolo Romita, Luigi Gargiulo, Alessandra Narcisi, Luigi Naldi

“…The main reasons for drug discontinuation (25/325, 7.7%) were adverse events (4.9%), including cutaneous or infectious diseases (1.5%), such as acne and herpes zoster; blood test changes (1.2%), including hypercholesterolemia, creatine phosphokinase or liver enzyme elevation, and lymphopenia; urinary or respiratory infections (0.9%); deep venous thrombosis (0.3%); malignancies (0.3%); loss of consciousness (0.3%); and arthralgias (0.3%); followed by ineffectiveness (0.6%). …”
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Impact of SGLT-2 inhibitors on modifiable cardiovascular risk factors in Romanian patients with type 2 diabetes mellitus by Adriana Gherbon, Mirela Frandes, Darius Dîrpeş, Romulus Timar, Bogdan Timar

“…Abstract Background Modifiable cardiovascular risk factors are high blood pressure, smoking, diabetes, sedentary lifestyle, obesity, and hypercholesterolemia. Aim To investigate the impact of sodium-glucose 2 co-transporter inhibitors (SGLT-2i) on modifiable cardiovascular risk factors in Romanian patients diagnosed with type 2 diabetes mellitus (T2DM). …”
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Effect of colchicine, methotrexate, and hydroxychloroquine therapy on cardiovascular outcomes in patients with calcium pyrophosphate crystal deposition disease by M. S. Eliseev, E. V. Cheremushkina, O. V. Zhelyabina, M. N. Chikina, A. A. Kapitonova, A. A. Novikova, E. I. Markelova, A. M. Lila

“…Poor CVD outcomes in CPPD are associated with age, hypercholesterolemia, chronic kidney disease, and a history of CVD. …”
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A bibliometric analysis of PCSK9 inhibitors from 2007 to 2022 by Qin Luo, Qin Luo, Zhenchu Tang, Zhenchu Tang, Panyun Wu, Panyun Wu, Zhangling Chen, Zhangling Chen, Zhenfei Fang, Zhenfei Fang, Fei Luo, Fei Luo

“…According to keyword analysis, “low density lipoprotein”, “familial hypercholesterolemia”, “PCSK9 inhibitor”, “PCSK9”, and “efficacy” are the five keywords with the highest frequency of co-occurrence.ConclusionThe past 15 years have witnessed a rapid and fruitful development of PCSK9 inhibitors. …”
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