A Population Genomics Approach to Assessing the Genetic Basis of Within-Host Microevolution Underlying Recurrent Cryptococcal Meningitis Infection by Johanna Rhodes, Mathew A. Beale, Mathieu Vanhove, Joseph N. Jarvis, Shichina Kannambath, John A. Simpson, Anthea Ryan, Graeme Meintjes, Thomas S. Harrison, Matthew C. Fisher, Tihana Bicanic

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Case report: Temozolomide induced hypermutation indicates an unfavorable response to immunotherapy in patient with gliomas by Jiapeng Liu, Shuli Hu, Haihui Jiang, Yong Cui, Yong Cui

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Realization of immune response features by dynamical system models by Mika Yoshida, Kinji Fuchikami, Tatsuya Uezu

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Prevalence of hypermutator isolates of Achromobacter spp. from cystic fibrosis patients by Winnie Ridderberg, Kurt Jensen Handberg, Niels Nørskov-Lauritsen

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Systematic evaluation of intratumoral and peripheral BCR repertoires in three cancers by Sofia V Krasik, Ekaterina A Bryushkova, George V Sharonov, Daria S Myalik, Elizaveta V Shurganova, Dmitry V Komarov, Irina A Shagina, Polina S Shpudeiko, Maria A Turchaninova, Maria T Vakhitova, Igor V Samoylenko, Dimitr T Marinov, Lev V Demidov, Vladimir E Zagaynov, Dmitriy M Chudakov, Ekaterina O Serebrovskaya

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The Many Facets of Therapy Resistance and Tumor Recurrence in Glioblastoma by Anshika Goenka, Deanna Tiek, Xiao Song, Tianzhi Huang, Bo Hu, Shi-Yuan Cheng

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Biased Immunoglobulin Genes Rearrangement in Mantle Cell Lymphoma: Hints to Identify the Normal B-cell Counterpart by Francesco Bertoni, Sergio B. Cogliatti, Daniela Capello, Xi-shan Hao, Hua-qing Wang, Hui-lai Zhang, Franco Cavalli

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Parallel evolution of linezolid-resistant Staphylococcus aureus in patients with cystic fibrosis by Nicholas J. Pitcher, Andries Feder, Nicholas Bolden, Christian F. Zirbes, Anthony J. Pamatmat, Linda Boyken, Jared J. Hill, Alyssa R. Bartels, Andrew L. Thurman, Valerie C. Reeb, Harry S. Porterfield, Ahmed M. Moustafa, Paul J. Planet, Anthony J. Fischer

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Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data by Daniel Gadala-Maria, Moriah Gidoni, Susanna Marquez, Jason A. Vander Heiden, Justin T. Kos, Corey T. Watson, Kevin C. O'Connor, Kevin C. O'Connor, Gur Yaari, Steven H. Kleinstein, Steven H. Kleinstein, Steven H. Kleinstein

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Activation-induced cytidine deaminase causes recurrent splicing mutations in diffuse large B-cell lymphoma by Maria S. Benitez-Cantos, Carlos Cano, Marta Cuadros, Pedro P. Medina

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Adaptive tuning of mutation rates allows fast response to lethal stress in Escherichia coli by Toon Swings, Bram Van den Bergh, Sander Wuyts, Eline Oeyen, Karin Voordeckers, Kevin J Verstrepen, Maarten Fauvart, Natalie Verstraeten, Jan Michiels

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Use of V H, D and J H immunoglobulin gene segments in Brazilian patients with chronic lymphocytic leukaemia (CLL) by Beatriz Jatobá Pimentel, Cláudio Gustavo Stefanoff, Aline Santos Moreira, Héctor N. Seuánez, Ilana Renault Zalcberg

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Overview and clinical significance of multiple mutations in individual genes in hepatocellular carcinoma by Taisuke Imamura, Yukiyasu Okamura, Keiichi Ohshima, Katsuhiko Uesaka, Teiichi Sugiura, Takaaki Ito, Yusuke Yamamoto, Ryo Ashida, Katsuhisa Ohgi, Shimpei Otsuka, Sumiko Ohnami, Takeshi Nagashima, Keiichi Hatakeyama, Takashi Sugino, Kenichi Urakami, Yasuto Akiyama, Ken Yamaguchi

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The Double Engines and Single Checkpoint Theory of Endometriosis by Che-Fang Hsu, Aye Aye Khine, Hsuan-Shun Huang, Tang-Yuan Chu

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A novel 4-gene prognostic signature for hypermutated colorectal cancer by Ge W, Cai W, Bai R, Hu W, Wu D, Zheng S, Hu H

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Evaluation of Somatic Hypermutation Status in Chronic Lymphocytic Leukemia (CLL) in the Era of Next Generation Sequencing by Sanjeev Kumar Gupta, David S. Viswanatha, Keyur P. Patel

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Somatic hypermutation of T cell receptor α chain contributes to selection in nurse shark thymus by Jeannine A Ott, Caitlin D Castro, Thaddeus C Deiss, Yuko Ohta, Martin F Flajnik, Michael F Criscitiello

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AID/APOBEC cytosine deaminase induces genome-wide kataegis by Lada Artem G, Dhar Alok, Boissy Robert J, Hirano Masayuki, Rubel Aleksandr A, Rogozin Igor B, Pavlov Youri I

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Different Somatic Hypermutation Levels among Antibody Subclasses Disclosed by a New Next-Generation Sequencing-Based Antibody Repertoire Analysis by Kazutaka Kitaura, Hiroshi Yamashita, Hitomi Ayabe, Tadasu Shini, Tadasu Shini, Takaji Matsutani, Ryuji Suzuki, Ryuji Suzuki

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Clinicopathological and mutational analyses of colorectal cancer with mutations in the POLE gene by Hitoshi Hino, Akio Shiomi, Masatoshi Kusuhara, Hiroyasu Kagawa, Yushi Yamakawa, Keiichi Hatakeyama, Takanori Kawabata, Takuma Oishi, Kenichi Urakami, Takeshi Nagashima, Yusuke Kinugasa, Ken Yamaguchi

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