Intravenously administered interleukin-7 to reverse lymphopenia in patients with septic shock: a double-blind, randomized, placebo-controlled trial by Thomas Daix, Armelle Mathonnet, Scott Brakenridge, Pierre-François Dequin, Jean-Paul Mira, Frederique Berbille, Michel Morre, Robin Jeannet, Teresa Blood, Jacqueline Unsinger, Jane Blood, Andrew Walton, Lyle L. Moldawer, Richard Hotchkiss, Bruno François

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Bispecific Antibodies in Cancer Immunotherapy: A Novel Response to an Old Question by Camila Ordóñez-Reyes, Juan Esteban Garcia-Robledo, Diego F. Chamorro, Andrés Mosquera, Liliana Sussmann, Alejandro Ruiz-Patiño, Oscar Arrieta, Lucia Zatarain-Barrón, Leonardo Rojas, Alessandro Russo, Diego de Miguel-Perez, Christian Rolfo, Andrés F. Cardona

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HLA-mismatched allogeneic adoptive immune therapy in patients with severely immunosuppressed AIDS: a multicenter, open-label, controlled, phase 2a study by Tao Yang, Zhiman Xie, Zhe Xu, Bo Tu, Huan Lu, Huihuang Huang, Lei Huang, Chao Zhang, Liying Gao, Lei Jin, Ping Ma, Jun Zou, Limin Liu, Cheng Zhen, Chunbao Zhou, Sirun Meng, Yuan-Yuan Li, Jin-Wen Song, Shixiong Yang, Hui-Sheng Ai, Yanmei Jiao, Ming Shi, Ruonan Xu, Fu-Sheng Wang

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Management Issues in Myasthenia Gravis Patients Living With HIV: A Case Series and Literature Review by Jeannine M. Heckmann, Jeannine M. Heckmann, Suzaan Marais, Suzaan Marais

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A Dual‐domain Engineered Antibody for Efficient HBV Suppression and Immune Responses Restoration by Yichao Jiang, Xiaoqing Chen, Xinya Ye, Can Wen, Tao Xu, Chao Yu, Wenjing Ning, Guosong Wang, Xinchu Xiang, Xiaomin Liu, Yalin Wang, Yuanzhi Chen, Xue Liu, Changrong Shi, Chao Liu, Quan Yuan, Yixin Chen, Tianying Zhang, Wenxin Luo, Ningshao Xia

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Serial Analysis of the T-Cell Receptor β-Chain Repertoire in People Living With HIV Reveals Incomplete Recovery After Long-Term Antiretroviral Therapy by Andrea M. H. Towlerton, Shashidhar Ravishankar, David G. Coffey, David G. Coffey, David G. Coffey, Camille E. Puronen, Camille E. Puronen, Edus H. Warren, Edus H. Warren

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Editorial: Challenges and solutions for the incomplete immune restoration in HIV-infected patients under antiretroviral therapy by Yi-Qun Kuang, Caijun Sun, Daniel R. Ram, Christiane Moog, Bin Su

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Progressive multifocal leukoencephalopathy in the clinical practice of a neurologist. Case report by Yuliana A. Belova, Sergey V. Kotov

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Cirrhosis Hampers Early and Rapid Normalization of Natural Killer Cell Phenotype and Function in Hepatitis C Patients Undergoing Interferon-Free Therapy by Elena Perpiñán, Elena Perpiñán, Sofía Pérez-Del-Pulgar, Sofía Pérez-Del-Pulgar, María-Carlota Londoño, María-Carlota Londoño, Zoe Mariño, Zoe Mariño, Concepción Bartres, Concepción Bartres, Patricia González, Patricia González, Mireia García-López, Mireia García-López, Elisa Pose, Sabela Lens, Sabela Lens, Mala K. Maini, Xavier Forns, Xavier Forns, George Koutsoudakis, George Koutsoudakis

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Immune restoration in HIV-1-infected patients after 12 years of antiretroviral therapy: a real-world observational study by Jiaye Liu, Lifeng Wang, Yuying Hou, Yan Zhao, Zhihui Dou, Ye Ma, Dawei Zhang, Yasong Wu, Decai Zhao, Zhongfu Liu, Fujie Zhang, Lei Jin, Ji-Yuan Zhang, Ruonan Xu, Ming Shi, Lei Huang, Zunyou Wu, Mengjie Han, George F. Gao, Fu-Sheng Wang

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Immune Restoration Disease in HIV Patient by Neil E. Jenkins, Mike B.J. Beadsworth, James J. Anson, Fred J. Nye, Vanessa J. Martlew, Nick J. Beeching

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HIV immunological non-responders are characterized by extensive immunosenescence and impaired lymphocyte cytokine production capacity by Wilhelm A. J. W. Vos, Wilhelm A. J. W. Vos, Adriana Navas, Elise M. G. Meeder, Elise M. G. Meeder, Marc J. T. Blaauw, Marc J. T. Blaauw, Albert L. Groenendijk, Albert L. Groenendijk, Albert L. Groenendijk, Louise E. van Eekeren, Twan Otten, Twan Otten, Nadira Vadaq, Vasiliki Matzaraki, Bram van Cranenbroek, Kees Brinkman, Jan van Lunzen, Leo A. B. Joosten, Leo A. B. Joosten, Mihai G. Netea, Mihai G. Netea, Willem L. Blok, Andre J. A. M. van der Ven, Hans J. P. M. Koenen, Janneke E. Stalenhoef

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When the Damage Is Done: Injury and Repair in Thymus Function by Sinéad Kinsella, Jarrod A. Dudakov, Jarrod A. Dudakov, Jarrod A. Dudakov

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CD4/CD8 ratio normalization rates and low ratio as prognostic marker for non-AIDS defining events among long-term virologically suppressed people living with HIV by Win Min Han, Tanakorn Apornpong, Stephen J. Kerr, Akarin Hiransuthikul, Sivaporn Gatechompol, Tanya Do, Kiat Ruxrungtham, Anchalee Avihingsanon

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Restoration of HCV-Specific Immune Responses with Antiviral Therapy: A Case for DAA Treatment in Acute HCV Infection by Julia L. Casey, Jordan J. Feld, Sonya A. MacParland

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Recovery of Innate Immune Cells and Persisting Alterations in Adaptive Immunity in the Peripheral Blood of Convalescent Plasma Donors at Eight Months Post SARS-CoV-2 Infection by Ioannis V. Kostopoulos, Nikolaos Orologas-Stavrou, Pantelis Rousakis, Chrysanthi Panteli, Ioannis Ntanasis-Stathopoulos, Ioanna Charitaki, Eleni Korompoki, Maria Gavriatopoulou, Efstathios Kastritis, Ioannis P. Trougakos, Meletios-Athanasios Dimopoulos, Ourania E. Tsitsilonis, Evangelos Terpos

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Immunomodulation by extracellular vesicle-like nanoparticles from marine macroalgae Sargassum fusiforme: Enhancing Type 1 T helper and cytotoxic T lymphocyte-mediated immune respon... by Hyeon Jin Lee, Ki-Won Shin, Seo Jun Lee, Ji Young Park, In Chul Lee, Hyung-Jun Kwon, Hyung Jae Jeong, Jae-Min Yuk, Young-Bae Ryu, Woo Sik Kim

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Editorial: Immunological non-responders in HIV infection by Evgeniya Saidakova, Evgeniya Saidakova, Konstantin Shmagel, Scott Sieg, Peter Hunt

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Hippo pathway-manipulating neutrophil-mimic hybrid nanoparticles for cardiac ischemic injury via modulation of local immunity and cardiac regeneration by Qiaozi Wang, Yanan Song, Jinfeng Gao, Qiyu Li, Jing Chen, Yifang Xie, Zhengmin Wang, Haipeng Tan, Hongbo Yang, Ning Zhang, Juying Qian, Zhiqing Pang, Zheyong Huang, Junbo Ge

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