S100A1 is released from ischemic cardiomyocytes and signals myocardial damage via Toll‐like receptor 4 by David Rohde, Christoph Schön, Melanie Boerries, Ieva Didrihsone, Julia Ritterhoff, Katharina F Kubatzky, Mirko Völkers, Nicole Herzog, Mona Mähler, James N Tsoporis, Thomas G Parker, Björn Linke, Evangelos Giannitsis, Erhe Gao, Karsten Peppel, Hugo A Katus, Patrick Most

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Combined Immune Defect in B-Cell Lymphoproliferative Disorders Is Associated with Severe Infection and Cancer Progression by Juliana Ochoa-Grullón, Kissy Guevara-Hoyer, Cristina Pérez López, Rebeca Pérez de Diego, Ascensión Peña Cortijo, Marta Polo, Marta Mateo Morales, Eduardo Anguita Mandley, Carlos Jiménez García, Estefanía Bolaños, Belén Íñigo, Fiorella Medina, Antonia Rodríguez de la Peña, Carmen Izquierdo Delgado, Eduardo de la Fuente Muñoz, Elsa Mayol, Miguel Fernández-Arquero, Ataúlfo González-Fernández, Celina Benavente Cuesta, Silvia Sánchez-Ramón

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Comparison of the safety and immunogenicity of the BNT-162b2 vaccine and the ChAdOx1 vaccine for solid organ transplant recipients: a prospective study by Aziza A. Ajlan, Tariq Ali, Hassan Aleid, Khalid Almeshari, Edward DeVol, Morad Ahmed Alkaff, Layal Fajji, Ali Alali, Dani Halabi, Sahar Althuwaidi, Saad Alghamdi, Asad Ullah, Abdulrahman Alrajhi, Khalid Bzeizi, Reem Almaghrabi, Kris Ann Hervera Marquez, Bilal Elmikkaoui, Eid Albogumi, Haifa Aldakhil, Moheeb Al-Awwami, Dieter C. Broering

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Genetic Associations and Differential mRNA Expression Levels of Host Genes Suggest a Viral Trigger for Endemic Pemphigus Foliaceus by Valéria Bumiller-Bini Hoch, Ana Flávia Kohler, Danillo G. Augusto, Sara Cristina Lobo-Alves, Danielle Malheiros, Gabriel Adelman Cipolla, Angelica Beate Winter Boldt, Karin Braun-Prado, Michael Wittig, Andre Franke, Claudia Pföhler, Margitta Worm, Nina van Beek, Matthias Goebeler, Miklós Sárdy, Saleh Ibrahim, Hauke Busch, Enno Schmidt, Jennifer Elisabeth Hundt, Patrícia Savio de Araujo-Souza, Maria Luiza Petzl-Erler

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Proteogenomics Reveals Orthologous Alternatively Spliced Proteoforms in the Same Human and Mouse Brain Regions with Differential Abundance in an Alzheimer’s Disease Mouse Model by Esdras Matheus Gomes da Silva, Letícia Graziela Costa Santos, Flávia Santiago de Oliveira, Flávia Cristina de Paula Freitas, Vinícius da Silva Coutinho Parreira, Hellen Geremias dos Santos, Raphael Tavares, Paulo Costa Carvalho, Ana Gisele da Costa Neves-Ferreira, Andrea Siqueira Haibara, Patrícia Savio de Araujo-Souza, Adriana Abalen Martins Dias, Fabio Passetti

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Analysis of the Origin of Emiratis as Inferred from a Family Study Based on <i>HLA-A</i>, <i>-C</i>, <i>-B</i>, -<i>DRB1</i>, and <i>-DQB1</i> Genes by Zain Al Yafei, Abdelhafidh Hajjej, Marion Alvares, Ayeda Al Mahri, Amre Nasr, Rajaa Mirghani, Ali Al Obaidli, Mohamed Al Seiari, Steven J. Mack, Medhat Askar, Hisham A. Edinur, Wassim Y. Almawi, Gehad ElGhazali

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Immunotherapy with 4-1BBL-Expressing iPS Cell‐Derived Myeloid Lines Amplifies Antigen-Specific T Cell Infiltration in Advanced Melanoma by Haruka Kuriyama, Satoshi Fukushima, Toshihiro Kimura, Hisashi Kanemaru, Azusa Miyashita, Etsuko Okada, Yosuke Kubo, Satoshi Nakahara, Aki Tokuzumi, Yuki Nishimura, Ikko Kajihara, Katsunari Makino, Jun Aoi, Shinichi Masuguchi, Hirotake Tsukamoto, Takashi Inozume, Rong Zhang, Tetsuya Nakatsura, Yasushi Uemura, Satoru Senju, Hironobu Ihn

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Race/ethnicity-stratified fine-mapping of the MHC locus reveals genetic variants associated with late-onset asthma by Eunice Y. Lee, Wonson Choi, Adam B. Burkholder, Lalith Perera, Jasmine A. Mack, Jasmine A. Mack, Frederick W. Miller, Michael B. Fessler, Donald N. Cook, Donald N. Cook, Peer W. F. Karmaus, Hideki Nakano, Stavros Garantziotis, Jennifer H. Madenspacher, John S. House, Farida S. Akhtari, Farida S. Akhtari, Charles S. Schmitt, David C. Fargo, Janet E. Hall, Alison A. Motsinger-Reif

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Immunoglobulin G genetic variation can confound assessment of antibody levels via altered binding to detection reagents by Ruth A Purcell, L Carissa Aurelia, Robyn Esterbauer, Lilith F Allen, Katherine A Bond, Deborah A Williamson, Janine M Trevillyan, Jason A Trubiano, Jennifer J Juno, Adam K Wheatley, Miles P Davenport, Thi HO Nguyen, Katherine Kedzierska, Stephen J Kent, Kevin John Selva, Amy W Chung

“…Validation of anti‐Ig clones should include evaluation of binding to relevant antibody variants, particularly as the role of immunogenetics upon humoral immunity is increasingly explored in diverse populations.…”
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Axial spondyloarthritis patients have altered mucosal IgA response to oral and fecal microbiota by Tejpal Gill, Patrick Stauffer, Mark Asquith, Ted Laderas, Tammy M. Martin, Tammy M. Martin, Sean Davin, Matthew Schleisman, Claire Ramirez, Kimberly Ogle, Ingrid Lindquist, Ingrid Lindquist, Justine Nguyen, Stephen R. Planck, Carley Shaut, Sarah Diamond, James T. Rosenbaum, James T. Rosenbaum, James T. Rosenbaum, James T. Rosenbaum, Lisa Karstens, Lisa Karstens

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Ruxolitinib does not completely abrogate the functional capabilities of TLR4/9 ligand-activated NK cells by Carmen Mestre-Durán, Carla Martín-Cortázar, Blanca García-Solís, Alicia Pernas, Lidia Pertíñez, Víctor Galán, Luisa Sisinni, Laura Clares-Villa, Alfonso Navarro-Zapata, Karima Al-Akioui, Adela Escudero, Adela Escudero, Cristina Ferreras, Antonio Pérez-Martínez, Antonio Pérez-Martínez, Antonio Pérez-Martínez

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Curation and expansion of the Human Phenotype Ontology for systemic autoinflammatory diseases improves phenotype-driven disease-matching by Willem Maassen, Geertje Legger, Ovgu Kul Cinar, Paul van Daele, Paul van Daele, Marco Gattorno, Brigitte Bader-Meunier, Brigitte Bader-Meunier, Carine Wouters, Tracy Briggs, Tracy Briggs, Lennart Johansson, Joeri van der Velde, Morris Swertz, Ebun Omoyinmi, Esther Hoppenreijs, Alexandre Belot, Alexandre Belot, Despina Eleftheriou, Roberta Caorsi, Florence Aeschlimann, Florence Aeschlimann, Guilaine Boursier, Paul Brogan, Matthias Haimel, Marielle van Gijn

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Role of ABO Blood Group in SARS-CoV-2 Infection in Households by Ales Janda, Corinna Engel, Jonathan Remppis, Sigrid Enkel, Andreas Peter, Sebastian Hörber, Tina Ganzenmueller, Sarah Schober, Christof Weinstock, Christof Weinstock, Christof Weinstock, Eva-Maria Jacobsen, Dorit Fabricius, Maria Zernickel, Thomas Stamminger, Andrea Dietz, Hans-Jürgen Groß, Sebastian F. N. Bode, Anneke D. M. Haddad, Roland Elling, Roland Elling, Maximilian Stich, Burkhard Tönshoff, Philipp Henneke, Philipp Henneke, Klaus-Michael Debatin, Axel R. Franz, Axel R. Franz, Hanna Renk

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Identification of Adult Patients With Classical Dyskeratosis Congenita or Cryptic Telomere Biology Disorder by Telomere Length Screening Using Age-modified Criteria by Mareike Tometten, Martin Kirschner, Robert Meyer, Matthias Begemann, Insa Halfmeyer, Margherita Vieri, Kim Kricheldorf, Angela Maurer, Uwe Platzbecker, Markus Radsak, Philippe Schafhausen, Selim Corbacioglu, Britta Höchsmann, C. Matthias Wilk, Claas Hinze, Jörg Chromik, Michael Heuser, Michael Kreuter, Steffen Koschmieder, Jens Panse, Susanne Isfort, Ingo Kurth, Tim H. Brümmendorf, Fabian Beier

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Exploring gastric cancer genetics: A turning point in common variable immunodeficiency by Silvia Sánchez-Ramón, MD, PhD, Jesús Fuentes-Antrás, MD, Nicholas L. Rider, MD, Pedro Pérez-Segura, MD, PhD, Eduardo de la Fuente-Muñoz, MD, Miguel Fernández-Arquero, PhD, Esmeralda Neves, MD, Rebeca Pérez de Diego, PhD, Alberto Ocaña, MD, PhD, Kissy Guevara-Hoyer, MD, PhD

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Something about Genetics in Psychiatry by Bakir Mehić

“…Genetics in psychiatry is based on the application of the achievements and methods of population’s genetics, immunogenetics, cytogenetics, molecular genetics and pharmacogenetics. …”
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Clinical and Immunological Profile of Anti-factor H Antibody Associated Atypical Hemolytic Uremic Syndrome: A Nationwide Database by Mamta Puraswani, Priyanka Khandelwal, Himanshi Saini, Savita Saini, Bahadur Singh Gurjar, Aditi Sinha, Rajashri Pramod Shende, Tushar Kanti Maiti, Abhishek Kumar Singh, Uma Kanga, Uma Ali, Indira Agarwal, Kanav Anand, Narayan Prasad, Padmaraj Rajendran, Rajiv Sinha, Anil Vasudevan, Anita Saxena, Sanjay Agarwal, Pankaj Hari, Arvind Sahu, Satyajit Rath, Satyajit Rath, Arvind Bagga

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TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells by Beatrice Claudia Cianciotti, Zulma Irene Magnani, Alessia Ugolini, Barbara Camisa, Barbara Camisa, Ivan Merelli, Valentina Vavassori, Alessia Potenza, Antonio Imparato, Francesco Manfredi, Danilo Abbati, Laura Perani, Antonello Spinelli, Eric Shifrut, Eric Shifrut, Eric Shifrut, Fabio Ciceri, Fabio Ciceri, Luca Vago, Luca Vago, Raffaella Di Micco, Luigi Naldini, Luigi Naldini, Pietro Genovese, Pietro Genovese, Eliana Ruggiero, Chiara Bonini, Chiara Bonini

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Effect of donor HSD17B13 genotype on patient survival after liver transplant: a retrospective cohort studyResearch in context by Julia Kozlitina, Naomi M. Cohen, Drew Sturtevant, Jonathan C. Cohen, Cathi Murphey-Half, Jerome G. Saltarrelli, Peter Jindra, Medhat Askar, Christine S. Hwang, Parsia A. Vagefi, Chantale Lacelle, Helen H. Hobbs, Malcolm P. MacConmara

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New drug-like small molecule antagonizes phosphatidylinositol (3,4,5)-trisphosphate (PIP3) in patients with conotruncal heart defects by Alaaeldin G. Fayez, PhD, Nora N. Esmaiel, PhD, Engy A. Ashaat, MD, Miral M. Refeat, PhD, Randa S. Lotfy, PhD, Haiam Abdel Raouf, PhD, Mona O. El Ruby, MD

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